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2-trans-6-cis-dodecadienal
Notes:
Used as a food additive [EAFUS]
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Bedoukian Research, Inc. Perfecting the Art of Chemistry Working closely with our customers to meet their requirements. Dr. Paul Bedoukian founded the company in 1972 to fill a niche as a supplier of high quality specialty aroma molecules. Today, we offer more than 350 high impact aroma chemicals, while providing custom manufacturing services to the pharmaceutical, agrochemical, and specialty chemical industries. US Email: Customer Service US Email: Customer Service US Voice: 1-203-830-4000 US Fax: 1-203-830-4010 Instagram Linkedin Recent News Products List: View Product(s): 341 e,z-2,6-DODECADIEN-1-AL ≥90.0% (trans,cis), Kosher SDS Powerful. Blends well with citrus and florals to add freshness and watery notes.
Has application in watermelon, parsley and mushroom flavors.
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 21662-13-5 (E,Z)-2,6-DODECADIENAL 95.0% (sum of isomers)
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M&U International LLC Steady supply & demand Meeting customers increasing demands at home as well as abroad. M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers. Email: Sales US Email: Sales Voice: +86-21-32515501 60762991 60762992 Fax: +86-21-32515502 64204960 US Voice: 908-359-9000 US Fax: 908-359-9002 News Product(s): A0614 E,Z-2,6-Dodecadien-1-al
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 04-87400 TRANS-2-CIS-6-DODECADIENAL
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| CAS Number: | 21662-13-5 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 244-515-0 | |
| FDA UNII: | 6CPL2532NR | |
| Beilstein Number: | 4374899 | |
| XlogP3-AA: | 3.80 (est) | |
| Molecular Weight: | 180.29060000 | |
| Formula: | C12 H20 O | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
| EFSA/JECFA Comments: | The chemical name in the UL should be changed to Dodeca-(2E,6Z)-dienal, in accordance with the CAS nr and the most recent speci?cations on stereoisomeric composition (Documentation provided to EFSA nr.10) | |
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 1197 2-trans-6-cis-dodecadienal |
| DG SANTE Food Flavourings: | 05.120 (E,Z)-2,6-dodecadienal |
| FEMA Number: | 3637 (E,Z)-2,6-dodecadienal |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 21662-13-5 ; 2-TRANS-6-CIS-DODECADIENAL |
Physical Properties:
| Appearance: | yellow clear liquid (est) |
| Assay: | 97.50 to 100.00 % sum of isomers |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.98700 to 0.99300 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 8.213 to 8.263 |
| Refractive Index: | 1.42500 to 1.43100 @ 20.00 °C. |
| Boiling Point: | 130.00 to 131.00 °C. @ 5.00 mm Hg |
| Boiling Point: | 115.00 °C. @ 0.10 mm Hg |
| Acid Value: | 1.50 max. KOH/g |
| Vapor Pressure: | 0.008000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 210.00 °F. TCC ( 98.89 °C. ) |
| logP (o/w): | 4.327 (est) |
| Shelf Life: | 36.00 month(s) or longer if stored properly. |
| Soluble in: | |
| alcohol | |
| water, 11.33 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor Type: fatty | |
| Odor Strength: | low , recommend smelling in a 10.00 % solution or less |
| citrus mandarin orange melon | |
| Odor Description: at 10.00 % in dipropylene glycol. | deep citrus mandarin orange melon |
| fatty green aldehydic spicy melon | |
| Odor Description: | Fatty, green, aldehydic with a spice and melon nuance Mosciano, Gerard P&F 18, No. 3, 53, (1993) |
| Flavor Type: green | |
| green herbal waxy aldehydic | |
| Taste Description: at 20.00 ppm. | Green, herbal, waxy and aldehydic Mosciano, Gerard P&F 18, No. 3, 53, (1993) |
| Odor and/or flavor descriptions from others (if found). | |
| Bedoukian Research | |
| e,z-2,6-DODECADIEN-1-AL ≥90.0% (trans,cis), Kosher | |
| Odor Description: | A fatty, green, aldehydic character with spice, melon undertones Powerful. Blends well with citrus and florals to add freshness and watery notes. |
| Taste Description: | green Has application in watermelon, parsley and mushroom flavors. |
Cosmetic Information:
| None found |
Suppliers:
| Bedoukian Research |
| e,z-2,6-DODECADIEN-1-AL
≥90.0% (trans,cis), Kosher Odor: A fatty, green, aldehydic character with spice, melon undertones Use: Powerful. Blends well with citrus and florals to add freshness and watery notes. Flavor: green Has application in watermelon, parsley and mushroom flavors. |
| BOC Sciences |
| For experimental / research use only. |
| (E,Z)-2,6-DODECADIENAL 95.0% (sum of isomers) |
| M&U International |
| E,Z-2,6-Dodecadien-1-al |
| Parchem |
| (E,Z)-2,6-dodecadien-1-al |
| Penta International |
| TRANS-2-CIS-6-DODECADIENAL |
Safety Information:
| European information : | |
| Most important hazard(s): | |
| None - None found. | |
|
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavor and fragrance agents | ||
| RIFM Fragrance Material Safety Assessment: Search | |||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| Recommendation for (E,Z)-2,6-dodecadienal usage levels up to: | |||
| 0.5000 % in the fragrance concentrate. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.012 (μg/capita/day) | ||
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.009 (μg/capita/day) | ||
| Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 1800 (μg/person/day) | ||
| Threshold of Concern: | 1800 (μg/person/day) | ||
| Structure Class: | I | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 12 | |||
| Click here to view publication 12 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | - | - | |
| beverages(nonalcoholic): | - | 2.00000 | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | - | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | 0.02000 | |
| fish products: | - | - | |
| frozen dairy: | - | - | |
| fruit ices: | - | - | |
| gelatins / puddings: | - | 2.00000 | |
| granulated sugar: | - | - | |
| gravies: | - | 5.00000 | |
| hard candy: | - | - | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | 0.02000 | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | 0.01000 | |
| snack foods: | - | 0.01000 | |
| soft candy: | - | 2.00000 | |
| soups: | - | 0.01000 | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
| Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). | |||
| Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. | |||
| average usage mg/kg | maximum usage mg/kg | ||
| Dairy products, excluding products of category 02.0 (01.0): | 5.70000 | 12.00000 | |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0): | 1.50000 | 14.25000 | |
| Edible ices, including sherbet and sorbet (03.0): | 0.90000 | 2.98000 | |
| Processed fruit (04.1): | - | - | |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | 5.00000 | 5.03000 | |
| Confectionery (05.0): | - | - | |
| Chewing gum (05.0): | - | - | |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 4.80000 | 11.55000 | |
| Bakery wares (07.0): | 8.00000 | 19.07000 | |
| Meat and meat products, including poultry and game (08.0): | - | - | |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | 0.90000 | 2.98000 | |
| Eggs and egg products (10.0): | 0.90000 | 2.98000 | |
| Sweeteners, including honey (11.0): | 0.90000 | 2.98000 | |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | 2.00000 | 5.00000 | |
| Foodstuffs intended for particular nutritional uses (13.0): | - | - | |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | 2.00000 | 4.43000 | |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | 1.00000 | 2.00000 | |
| Ready-to-eat savouries (15.0): | 2.50000 | 4.50000 | |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 0.90000 | 2.98000 | |
Safety References:
| Flavor & Extract Manufacturers Association (FEMA) reference(s): | |
| The FEMA GRAS assessment of alpha,beta-unsaturated aldehydes and related substances used as flavor ingredients. View pdf | |
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 200, Revision 1 (FGE.200 Rev.1): 74 a,ß-unsaturated aliphatic aldehydes and precursors from chemical subgroup 1.1.1 of FGE.19 View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 70, Revision 1 (FGE.70Rev1): consideration of aliphatic, linear, a,ß-unsaturated, di- and trienals and related alcohols, acids and esters evaluated by JECFA (61st-68th-69th meeting) View page or View pdf | |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 21662-13-5 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 6430759 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| (2E,6Z)-dodeca-2,6-dienal | |
| Chemidplus: | 0021662135 |
References:
| (2E,6Z)-dodeca-2,6-dienal | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 21662-13-5 |
| Pubchem (cid): | 6430759 |
| Pubchem (sid): | 135263324 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| HMDB (The Human Metabolome Database): | HMDB32531 |
| FooDB: | FDB010401 |
| Export Tariff Code: | 2912.19.9000 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
Potential Blenders and core components note
Potential Uses:
| aldehydic | FR | |
| citrus | FR | |
| fat | FL | |
| fungus | FR | |
| green | FR | |
| mandarin | FR | |
| melon | FR | |
| parsley leaf | FL/FR | |
| reseda | FR | |
| spice | FR | |
| waxy |
Occurrence (nature, food, other): note
| orange peel oil Search Trop Picture |
Synonyms:
| (2E,6Z)- | dodeca-2,6-dienal |
| (2trans,6cis)- | dodeca-2,6-dienal |
| (E,Z)-2,6- | dodecadien-1-al |
| (E)-2,(Z)-6- | dodecadien-1-al |
| 2-trans-6-cis- | dodecadien-1-al |
| 2,6- | dodecadien-1-al |
| E,Z-2,6- | dodecadien-1-al |
| trans-2,cis-6- | dodecadien-1-al |
| trans,cis-2,6- | dodecadien-1-al |
| 2-trans-6-cis- | dodecadienal |
| trans-2-cis-6- | dodecadienal |
| trans,cis-2,6- | dodecadienal |
| 2,6- | dodecadienal, (2E,6Z)- |