Articles:
| Info: | epoxides |
(1S,4R,6S)-1-methyl-4-(prop-1-en-2-yl)-7-oxabicyclo[4.1.0]heptan-2-one
Notes:
None found
| CAS Number: | 18383-49-8 |  3D/inchi
|
| FDA UNII: | TV5341W478 | |
| Nikkaji Web: | J1.028.092C | |
| CoE Number: | 10501 | |
| XlogP3-AA: | 1.60 (est) | |
| Molecular Weight: | 166.21998000 | |
| Formula: | C10 H14 O2 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 1572 trans-carvone-5,6-oxide |
| FEMA Number: | 4084 trans-carvone-5,6-oxide |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 18383-49-8 ; CIS-CARVONE OXIDE |
| FDA Regulation: | |
| FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart F--Flavoring Agents and Related Substances Sec. 172.515 Synthetic flavoring substances and adjuvants. | |
Physical Properties:
| Appearance: | colorless clear liquid (est) |
| Assay: | 96.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.02700 to 1.03300 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 8.546 to 8.596 |
| Refractive Index: | 1.48100 to 1.48700 @ 20.00 °C. |
| Boiling Point: | 105.00 °C. @ 5.00 mm Hg |
| Acid Value: | 1.00 max. KOH/g |
| Vapor Pressure: | 0.016000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 225.00 °F. TCC ( 107.22 °C. ) |
| logP (o/w): | 1.110 |
| Soluble in: | |
| alcohol | |
| water, 221.1 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor Type: minty | |
| Odor Strength: | medium |
| Substantivity: | 20 hour(s) at 100.00 % |
| sweet caraway minty spearmint spicy | |
| Odor Description: at 100.00 %. | sweet caraway mint spearmint spicy Luebke, William tgsc, (1985) |
| Flavor Type: minty | |
| minty spicy spearmint carvone peppery | |
| Taste Description: | sweet minty spicy spearmint carvone peppery Luebke, William tgsc, (1985) |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Axsyn |
| For experimental / research use only. |
| 7-Oxabicyclo[4.1.0]heptan-2-one,1-methyl-4-(1-methylethenyl)-, (1S,4R,6S)- |
| Parchem |
| cis-carvone-5,6-oxide |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavor and fragrance agents | ||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| Recommendation for cis-carvone-5,6-oxide usage levels up to: | |||
| 5.0000 % in the fragrance concentrate. | |||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 22 | |||
| Click here to view publication 22 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | 3.00000 | 15.00000 | |
| beverages(nonalcoholic): | - | - | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | 2.00000 | 10.00000 | |
| cheese: | 2.00000 | 10.00000 | |
| chewing gum: | - | - | |
| condiments / relishes: | 5.00000 | 25.00000 | |
| confectionery froastings: | - | - | |
| egg products: | 2.00000 | 10.00000 | |
| fats / oils: | 2.00000 | 10.00000 | |
| fish products: | 3.00000 | 15.00000 | |
| frozen dairy: | 5.00000 | 25.00000 | |
| fruit ices: | 1.00000 | 5.00000 | |
| gelatins / puddings: | - | - | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | - | - | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | - | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | 3.00000 | 15.00000 | |
| poultry: | - | - | |
| processed fruits: | 1.00000 | 5.00000 | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | 2.00000 | 10.00000 | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 442462 |
| National Institute of Allergy and Infectious Diseases: | Data |
| (1S,4R,6S)-1-methyl-4-(prop-1-en-2-yl)-7-oxabicyclo[4.1.0]heptan-2-one | |
| Chemidplus: | 0018383498 |
References:
| (1S,4R,6S)-1-methyl-4-(prop-1-en-2-yl)-7-oxabicyclo[4.1.0]heptan-2-one | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 442462 |
| Pubchem (sid): | 135299874 |
| Pherobase: | View |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| KEGG (GenomeNet): | C09841 |
| HMDB (The Human Metabolome Database): | Search |
| FooDB: | FDB015988 |
| Typical G.C. | |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
Potential Blenders and core components note
Potential Uses:
| clean | ||
| herbal | FR | |
| mint | FR | |
| spice | FR |
Occurrence (nature, food, other): note
| dalechampia magnoliifolia Search Trop Picture | |
| spearmint oil Search Trop Picture | |
| valerian root oil CO2 extract china @ 0.14% Data GC Search Trop Picture |
Synonyms:
| 7-oxa | bicyclo[4.1.0]heptan-2-one, 1-methyl-4- (1-methylethenyl)-, (1a,4a,6a)-(+)- |
| cis- | carvone oxide |
| (1S,4R,6S)-1,6- | epoxy-p-menth-8-en-2-one |
| 5,6- | epoxy-p-menth-8-en-2-one |
| (1S,4R,6S)-1,6- | epoxy-para-menth-8-en-2-one |
| 5,6- | epoxy-para-menth-8-en-2-one |
| p- | menth-8-en-2-one, 1,6-epoxy-, (1R,4R,6R)-(-)- |
| (1S-(1alpha,4beta,6alpha))-1- | methyl-4-(1-methyl ethenyl)-7-oxabicyclo(4.1.0)heptan-2-one |
| (1S-(1alpha,4beta,6alpha))-1- | methyl-4-(1-methylethenyl)-7-oxabicyclo(4.1.0)heptan-2-one |
| (1a,4a,6a)-(+)-1- | methyl-4-(1-methylvinyl)-7-oxabicyclo[4.1.0]heptan-2-one |
| (1S,4R,6S)-1- | methyl-4-(prop-1-en-2-yl)-7-oxabicyclo[4.1.0]heptan-2-one |