Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless to pale yellow clear liquid (est) |
Assay: | 95.00 to 100.00 %
|
Food Chemicals Codex Listed: | No |
Specific Gravity: | 0.99250 to 1.00250 @ 25.00 °C.
|
Pounds per Gallon - (est).: | 8.259 to 8.342
|
Refractive Index: | 1.48900 to 1.49700 @ 20.00 °C.
|
Boiling Point: | 214.00 to 215.00 °C. @ 760.00 mm Hg
|
Vapor Pressure: | 0.273000 mmHg @ 25.00 °C. (est) |
Vapor Density: | 5.7 ( Air = 1 ) |
Flash Point: | 176.00 °F. TCC ( 80.00 °C. )
|
logP (o/w): | 2.547 (est) |
Shelf Life: | 24.00 month(s) or longer if stored properly. |
Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
Soluble in: |
| alcohol | | water, 229.6 mg/L @ 25 °C (est) |
Stability: |
| stable in most media |
Organoleptic Properties:
|
Odor Type: green |
|
| pea green pea pepper bell pepper green galbanum |
Odor Description: at 0.10 % in dipropylene glycol. | green pea green bell pepper green pea galbanum |
|
|
Flavor Type: green |
|
| green pepper bell pepper pea green pea galbanum |
Taste Description:
| green bell pepper green pea galbanum |
|
Odor and/or flavor descriptions from others (if found). |
|
R C Treatt & Co Ltd |
2-IsoButyl-3-methoxypyrazine Halal, Kosher |
Odor Description: | Green pea, green bell-pepper-like |
Taste Description: | Green pea, green bell-pepper-like Used at very low levels in green vegetable flavours: 0.0005-0.05ppm, and in galbanum substitutes. |
|
Moellhausen |
2-METHOXY-3-ISOBUTYL PYRAZINE |
Odor Description: | green, pepper |
Taste Description: | strong green note |
|
Indukern F&F |
2-METHOXY-3(6)-ISOBUTYL PYRAZINE |
Odor Description: | GREEN PAPRIKA, EARTHY, GALBANUM |
|
Pell Wall Perfumes |
Galbanum Pyrazine |
Odor Description: | bell-pepper, peas, galbanum, natural, nutty, roasted As with all pyrazines this is used in tiny traces – Galbanum Pyrazine at 0.1% in DPG is is deceptively nutty, but further dilution will reveal the strong green aspects of bell peppers, peas and galbanum.
This material is present in the scent of coffee as well as parsnip, green beans and spinach as well as peppers, so it’s surprisingly versatile.
Even at this dilution this is a very strong material that can enhance or contribute to green notes, give great diffusion and a very natural effect. |
|
Perfumery Laboratory |
Galbanum pyrazin 0.1% in DPG Ventós (GALBANUM PYRAZINE Ventós) |
Odor Description: | Bright, fresh, natural, sweet aroma of juicy fruits bell peppers with light notes of galbanum |
Taste Description: | green bell pepper green pea galbanum |
|
|
Cosmetic Information:
Suppliers:
Advanced Biotech |
2 METHOXY 3 ISO BUTYL PYRAZINE
|
Ambles Nature et Chimie |
2-METHOXY-3-ISOBUTYL PYRAZINE
|
Anhui Haibei |
2-isoButyl-3-methoxy Pyrazine
|
Anhui Haibei |
2-isobutyl-3(5/6) methoxy pyrazine
Odor: Green bell pepper green pea galbanum |
Augustus Oils |
2 Iso Butyl 3-6 Methoxy Pyrazine
|
Services |
Beijing Lys Chemicals |
2-isobutyl-3-methoxypyrazine
|
BOC Sciences |
For experimental / research use only. |
2-isoButyl-3-methoxypyrazine 95%
|
Citrus and Allied Essences |
2-isoButyl-3-Methoxy Pyrazine
|
Market Report |
DeLong Chemicals America |
2-Isobutyl-3-methoxypyrazine
|
Diffusions Aromatiques |
2-isoBUTYL-3-METHOXYPYRAZINE
|
Endeavour Specialty Chemicals |
2-Isobutyl-3-methoxypyrazine
|
Speciality Chemical Product Groups |
Ernesto Ventós |
2-isoBUTYL-3-METHOXYPYRAZINE
Odor: PEPPER,GREEN,PEA,EARTH,PUNGENT |
FCI SAS |
2-METHOXY-3-ISOBUTYL PYRAZINE
Odor: Coffee, pepper, earthy |
Fleurchem |
2-methoxy 3-isobutyl pyrazine
|
Frutarom |
2-METHOXY-(3 OR 6)-ISOBUTYLPYRAZINE
KOSHER Flavor: Green, Pea, Pepper, Galbanum |
CBD Offering |
Frutarom |
2-METHOXY-3-ISOBUTYLPYRAZINE
KOSHER Flavor: Pea, Green, Peppery, Galbanum |
IFF |
2-METHOXY-3-ISOBUTYLPYRAZINE
KOSHER Flavor: Pea, Green, Peppery, Galbanum |
IFF |
2-METHOXY-3-ISOBUTYLPYRAZINE
KOSHER Flavor: Pea, Green, Peppery, Galbanum |
Indukern F&F |
2-METHOXY-3(6)-ISOBUTYL PYRAZINE
Odor: GREEN PAPRIKA, EARTHY, GALBANUM |
Jiangyin Healthway |
2-Methoxy-3-isobutyl pyrazine
|
New functional food ingredients |
Jinan Enlighten Chemical Technology(Wutong Aroma ) |
2-Methoxy-3-isobutyl pyrazine, Kosherk
|
Kingchem Laboratories |
2 METHOXY 3 ISOBUTYLPYRAZINE (2-Isobutyl-3-methoxypyrazine)
Odor: Coffee, green pepper |
Lluch Essence |
PYRAZINE 2-METHOXY-3-ISOBUTYL
|
Lluch Essence |
PYRAZINE 2-METHOXY-3-ISOBUTYL
|
Lluch Essence |
PYRAZINE 2-METHOXY-3(6)-ISOBUTYL
|
M&U International |
2-METHOXY-3-ISOBUTYL PYRAZINE, Kosher
|
Moellhausen |
2-METHOXY-3-ISOBUTYL PYRAZINE 1% DPG
|
Moellhausen |
2-METHOXY-3-ISOBUTYL PYRAZINE
Odor: green, pepper Flavor: strong green note |
Pearlchem Corporation |
2-Methoxy-3-isobutyl Pyrazine
|
Pell Wall Perfumes |
Galbanum Pyrazine
Odor: bell-pepper, peas, galbanum, natural, nutty, roasted Use: As with all pyrazines this is used in tiny traces – Galbanum Pyrazine at 0.1% in DPG is is deceptively nutty, but further dilution will reveal the strong green aspects of bell peppers, peas and galbanum.
This material is present in the scent of coffee as well as parsnip, green beans and spinach as well as peppers, so it’s surprisingly versatile.
Even at this dilution this is a very strong material that can enhance or contribute to green notes, give great diffusion and a very natural effect. |
Penta International |
2-METHOXY-3-ISOBUTYLPYRAZINE
|
Perfumery Laboratory |
Galbanum pyrazin 0.1% in DPG Ventós (GALBANUM PYRAZINE Ventós)
Odor: Bright, fresh, natural, sweet aroma of juicy fruits bell peppers with light notes of galbanum |
Phoenix Aromas & Essential Oils |
Pyrazine, 2-Methoxy-3-Isobutyl
|
R C Treatt & Co Ltd |
2-IsoButyl-3-methoxypyrazine
Halal, Kosher Odor: Green pea, green bell-pepper-like Flavor: Green pea, green bell-pepper-like Used at very low levels in green vegetable flavours: 0.0005-0.05ppm, and in galbanum substitutes. |
Reincke & Fichtner |
2-isoButyl-3-methoxypyrazine
|
Robinson Brothers |
2-isobutyl-3-methoxypyrazine F&F
|
https://www.robinsonbrothers.uk/chemistry-competences |
Santa Cruz Biotechnology |
For experimental / research use only. |
2-isoButyl-3-methoxypyrazine ≥97%
|
Sigma-Aldrich |
2-Isobutyl-3-methoxypyrazine, ≥99%, FG
Odor: green; vegetable; pepper |
Certified Food Grade Products |
SRS Aromatics |
2-ISOBUTYL-3-METHOXY PYRAZINE
|
Sunaux International |
2-Methoxy-3-isobutyl Pyrazine
|
Synerzine |
2-Methoxy-3-Isobutylpyrazine
also named commonly as 2-Isobutyl-3-Methoxypyrazine |
Taytonn ASCC |
2-Isobutyl-3(5/6)-Methoxypyrazine
Odor: Earthy, Galbanum, Green, Peppery |
TCI AMERICA |
For experimental / research use only. |
2-isoButyl-3-methoxypyrazine >97.0%(GC)(T)
|
Tengzhou Jitian Aroma Chemiclal |
2-Methoxy -3 - isobutyl pyrazine
|
Tengzhou Xiang Yuan Aroma Chemicals |
2-Methoxy-3-Isobutyl Pyrazine
|
Tianjin Danjun International |
2-Isobutyl-3-methoxypyrazine
|
United International |
2-Methoxy-3-Isobutyl Pyrazine
|
Vigon International |
isoButyl-2 Methoxy-3 Pyrazine
|
WholeChem |
2-Methoxy-3-isobutyl pyrazine
|
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xi - Irritant |
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
|
|
Hazards identification |
|
Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
|
Pictogram | |
|
Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
gavage-mouse LD50 2000 mg/kg (Quest International, 1983a)
gavage-rat LD50 > 4000 mg/kg (Roure Inc., 1974)
|
Dermal Toxicity: |
Not determined
|
Inhalation Toxicity: |
Not determined
|
Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for 2-isobutyl-3-methoxypyrazine usage levels up to: | | 0.1000 % in the fragrance concentrate.
|
|
Maximised Survey-derived Daily Intakes (MSDI-EU): | 1.60 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 1.00 (μg/capita/day) |
Structure Class: | II |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 4 |
Click here to view publication 4 |
| average usual ppm | average maximum ppm |
baked goods: | - | 0.05000 |
beverages(nonalcoholic): | - | 0.05000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | 0.05000 |
cheese: | - | - |
chewing gum: | - | 0.05000 |
condiments / relishes: | - | 0.05000 |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 0.05000 |
fruit ices: | - | 0.05000 |
gelatins / puddings: | - | 0.05000 |
granulated sugar: | - | - |
gravies: | - | 0.05000 |
hard candy: | - | 0.05000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | 0.05000 |
milk products: | - | 0.05000 |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | 0.05000 |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s): |
The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. View pdf |
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf |
Flavouring Group Evaluation 50 (FGE.50): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) [1] View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 50, Revision 1 (FGE.50Rev1): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17Rev2 (2010) View page or View pdf |
Safety and efficacy of pyrazine derivatives including saturated ones belonging to chemical group 24 when used as flavourings for all animal species View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 24683-00-9 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 32594 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 3 |
| 2-methoxy-3-(2-methylpropyl)pyrazine |
Chemidplus: | 0024683009 |
References:
Other Information:
Potential Blenders and core components note
|
For Odor |
aldehydic |
| citrus carbaldehyde | FR |
| decanal (aldehyde C-10) | FL/FR |
| dodecanal (aldehyde C-12 lauric) | FL/FR |
amber |
| ambroxan | FL/FR |
animal |
| animal carbolactone | FR |
| costus valerolactone | FR |
para- | cresyl caprylate | FL/FR |
anise |
| anise seed oil colombia | FL/FR |
anisic |
| ocimum basilicum herb oil | FL/FR |
balsamic |
iso | amyl benzoate | FL/FR |
| amyris wood oil | FL/FR |
siam | benzoin resinoid | FL/FR |
| benzyl benzoate | FL/FR |
| benzyl salicylate | FL/FR |
| cinnamyl alcohol | FL/FR |
| clover nitrile | FR |
| cotinus coggygria branch/leaf oil | FL/FR |
| fir balsam absolute | FR |
| fir needle oil siberia | FL/FR |
3- | phenyl propyl alcohol | FL/FR |
berry |
| raspberry ketone methyl ether | FL/FR |
camphoreous |
| camphor tree bark oil | FL/FR |
caramellic |
| strawberry furanone | FL/FR |
citrus |
| dihydromyrcenol | FL/FR |
| grapefruit pentanol | FR |
(E)-2- | tetradecenal | FL/FR |
earthy |
| bean pyrazine | FL/FR |
2- | ethyl-3-methoxypyrazine | FL/FR |
floral |
| benzyl alcohol | FL/FR |
| bois de rose oil brazil | FL/FR |
| citronellyl acetate | FL/FR |
| cyclamen aldehyde | FL/FR |
| cyclohexyl ethyl alcohol | FL/FR |
| floral pyranol | FR |
| geranyl acetate | FL/FR |
(E)- | geranyl acetone | FL/FR |
| geranyl isobutyrate | FL/FR |
| heliotropyl diethyl acetal | FR |
(Z)-3- | hexen-1-yl salicylate | FL/FR |
| hexyl 2-furoate | FL/FR |
alpha- | hexyl cinnamaldehyde | FL/FR |
| hyacinth ether | FR |
| leerall | FR |
laevo- | linalool | FL/FR |
| linalool oxide | FL/FR |
| methyl dihydrojasmonate | FL/FR |
| mimosa absolute france | FL/FR |
| muguet carboxaldehyde | FR |
| muguet octadienol | FR |
| neryl acetate | FL/FR |
| ocean propanal | FL/FR |
| orris pyridine 25% IPM | FR |
| phenethyl acetate | FL/FR |
| phenethyl salicylate | FL/FR |
| reseda acetal | FR |
| violet methyl carbonate | FR |
fruity |
| allyl amyl glycolate | FR |
iso | butyl hexanoate | FL/FR |
| butyl isovalerate | FL/FR |
gamma- | decalactone | FL/FR |
| ethyl 2-cyclohexyl propionate | FR |
| fleuramone (IFF) | FR |
| green acetate | FR |
| propyl 2,4-decadienoate | FL/FR |
| rhubarb undecane | FR |
gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
green |
| acetaldehyde butyl phenethyl acetal | FL/FR |
| acetaldehyde ethyl phenethyl acetal | FL/FR |
S-sec- | butyl thioisovalerate | FL/FR |
2-sec- | butyl-3-methoxypyrazine | FL/FR |
| cortex pyridine | FL/FR |
para- | dimethyl hydroquinone | FL/FR |
| galbanum decatriene | FL/FR |
| galbanum oil terpeneless | FL/FR |
| galbanum oleoresin | FL/FR |
| galbanum oxyacetate | FR |
| galbanum resinoid | FL/FR |
| galbascone (IFF) | FR |
2- | heptyl tetrahydrofuran | FR |
(Z)-3- | hexen-1-yl benzoate | FL/FR |
(Z)-3- | hexen-1-yl propionate | FL/FR |
| hexyl 2-methyl butyrate | FL/FR |
| hexyl tiglate | FL/FR |
2,4- | ivy carbaldehyde | FL/FR |
(Z)- | leaf acetal | FL/FR |
| leafy oxime | FR |
| melon nonenoate | FL/FR |
| methyl heptine carbonate | FL/FR |
| methyl octine carbonate | FL/FR |
| narcissus flower absolute | FR |
(E,Z)-2,6- | nonadien-1-ol | FL/FR |
(E,Z)-3,6- | nonadien-1-ol | FL/FR |
(E,Z)-2,6- | nonadienal | FL/FR |
| phenyl acetaldehyde | FL/FR |
| phenyl acetaldehyde dimethyl acetal | FL/FR |
3- | phenyl propionaldehyde | FL/FR |
| pineapple heptadienone 10% | FR |
iso | propyl 3-methyl thiocrotonate | FL/FR |
iso | propyl thioisovalerate | FL/FR |
| sorbyl isobutyrate | FL/FR |
| styralyl acetate | FL/FR |
| violet dienyne | FR |
herbal |
| carum carvi fruit oil | FL/FR |
| clary sage oil france | FL/FR |
| daucus carota fruit oil | FL/FR |
| lavender absolute bulgaria | FL/FR |
honey |
| phenyl acetic acid | FL/FR |
marine |
green | algae absolute | FL/FR |
| marine hexane | FR |
melon |
| melon heptenal | FL/FR |
| watermelon ketone | FR |
mossy |
| oakmoss absolute | FL/FR |
| veramoss (IFF) | FR |
nutty |
| shoyu pyrazine | FL/FR |
powdery |
para- | anisyl alcohol | FL/FR |
spicy |
| cubeb oil | FL/FR |
| cumin seed oil | FL/FR |
| cuminaldehyde | FL/FR |
| levisticum officinale root oil | FL/FR |
black | pepper oil | FL/FR |
| pimenta acris leaf oil | FL/FR |
terpenic |
| frankincense oil | FL/FR |
| juniperus communis fruit oil | FL/FR |
alpha- | terpineol | FL/FR |
tonka |
| flouve absolute | FR |
| tonka bean absolute | FR |
tropical |
| ethyl (Z)-3-hexenoate | FL/FR |
cis- | galbanum oxathiane | FL/FR |
2- | tropical oxathiane | FL/FR |
waxy |
| decyl acetate | FL/FR |
1- | dodecanol | FL/FR |
| ethyl laurate | FL/FR |
1- | undecanol | FL/FR |
woody |
| cistus twig/leaf oil | FL/FR |
| myrtenyl isobutyrate | |
| patchouli ethanone | FR |
| santall | FR |
| spruce needle oil canada | FL/FR |
| thuja occidentalis leaf oil | FL/FR |
| tobacarol (IFF) | FR |
| vetiver oil haiti | FL/FR |
| woody acetate | FR |
(Z)- | woody amylene | FR |
| woody propanol | FR |
|
For Flavor |
|
No flavor group found for these |
green | algae absolute | FL/FR |
| bean pyrazine | FL/FR |
S-sec- | butyl thioisovalerate | FL/FR |
| cotinus coggygria branch/leaf oil | FL/FR |
| ethyl (Z)-3-hexenoate | FL/FR |
2- | ethyl-3-methoxypyrazine | FL/FR |
| green pea pyrazine | FL |
2- | methoxy-3-propyl pyrazine | FL |
| myrtenyl isobutyrate | |
2- | pentyl pyridine | FL |
iso | propyl 3-methyl thiocrotonate | FL/FR |
iso | propyl thioisovalerate | FL/FR |
|
| sorbyl isobutyrate | FL/FR |
aldehydic |
1- | undecanol | FL/FR |
animal |
para- | cresyl caprylate | FL/FR |
anise |
| anise seed oil colombia | FL/FR |
apple |
(E,Z)-2,6- | nonadien-1-ol | FL/FR |
balsamic |
siam | benzoin resinoid | FL/FR |
| benzyl benzoate | FL/FR |
| benzyl salicylate | FL/FR |
| fir needle oil siberia | FL/FR |
berry |
| raspberry ketone methyl ether | FL/FR |
camphoreous |
| camphor tree bark oil | FL/FR |
caramellic |
| strawberry furanone | FL/FR |
citrus |
laevo- | linalool | FL/FR |
alpha- | terpineol | FL/FR |
creamy |
gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
fatty |
(Z)-3- | hexen-1-yl benzoate | FL/FR |
floral |
| bois de rose oil brazil | FL/FR |
| citronellyl acetate | FL/FR |
(E)- | geranyl acetone | FL/FR |
| geranyl isobutyrate | FL/FR |
| methyl dihydrojasmonate | FL/FR |
| neryl acetate | FL/FR |
| ocean propanal | FL/FR |
| phenyl acetic acid | FL/FR |
fruity |
iso | amyl benzoate | FL/FR |
para- | anisyl alcohol | FL/FR |
| benzyl alcohol | FL/FR |
iso | butyl hexanoate | FL/FR |
| butyl isovalerate | FL/FR |
gamma- | decalactone | FL/FR |
| styralyl acetate | FL/FR |
green |
| acetaldehyde butyl phenethyl acetal | FL/FR |
| acetaldehyde ethyl phenethyl acetal | FL/FR |
| cinnamyl alcohol | FL/FR |
| cortex pyridine | FL/FR |
| cyclamen aldehyde | FL/FR |
| cyclohexyl ethyl alcohol | FL/FR |
| dihydromyrcenol | FL/FR |
para- | dimethyl hydroquinone | FL/FR |
| galbanum decatriene | FL/FR |
| galbanum oil terpeneless | FL/FR |
| galbanum oleoresin | FL/FR |
cis- | galbanum oxathiane | FL/FR |
| galbanum resinoid | FL/FR |
| geranyl acetate | FL/FR |
(Z)-3- | hexen-1-yl propionate | FL/FR |
(Z)-3- | hexen-1-yl salicylate | FL/FR |
| hexyl 2-furoate | FL/FR |
| hexyl 2-methyl butyrate | FL/FR |
| hexyl tiglate | FL/FR |
2,4- | ivy carbaldehyde | FL/FR |
(Z)- | leaf acetal | FL/FR |
| linalool oxide | FL/FR |
| melon heptenal | FL/FR |
| melon nonenoate | FL/FR |
| methyl heptine carbonate | FL/FR |
| methyl octine carbonate | FL/FR |
(E,Z)-3,6- | nonadien-1-ol | FL/FR |
(E,Z)-2,6- | nonadienal | FL/FR |
| oakmoss absolute | FL/FR |
| phenyl acetaldehyde dimethyl acetal | FL/FR |
3- | phenyl propionaldehyde | FL/FR |
herbal |
| carum carvi fruit oil | FL/FR |
| clary sage oil france | FL/FR |
| daucus carota fruit oil | FL/FR |
| lavender absolute bulgaria | FL/FR |
| ocimum basilicum herb oil | FL/FR |
honey |
| phenethyl acetate | FL/FR |
| phenyl acetaldehyde | FL/FR |
medicinal, |
| phenethyl salicylate | FL/FR |
melon |
| propyl 2,4-decadienoate | FL/FR |
musty |
| shoyu pyrazine | FL/FR |
orris |
| costus root oil | FL |
soapy |
| dodecanal (aldehyde C-12 lauric) | FL/FR |
1- | dodecanol | FL/FR |
spicy |
| cubeb oil | FL/FR |
| cumin seed oil | FL/FR |
| cuminaldehyde | FL/FR |
| levisticum officinale root oil | FL/FR |
black | pepper oil | FL/FR |
3- | phenyl propyl alcohol | FL/FR |
| pimenta acris leaf oil | FL/FR |
terpenic |
| juniperus communis fruit oil | FL/FR |
tropical |
2- | tropical oxathiane | FL/FR |
vegetable |
2-sec- | butyl-3-methoxypyrazine | FL/FR |
waxy |
| decanal (aldehyde C-10) | FL/FR |
| decyl acetate | FL/FR |
| ethyl laurate | FL/FR |
alpha- | hexyl cinnamaldehyde | FL/FR |
| mimosa absolute france | FL/FR |
(E)-2- | tetradecenal | FL/FR |
woody |
| ambroxan | FL/FR |
| amyris wood oil | FL/FR |
| cistus twig/leaf oil | FL/FR |
| frankincense oil | FL/FR |
| spruce needle oil canada | FL/FR |
| thuja occidentalis leaf oil | FL/FR |
| vetiver oil haiti | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
iso | butyl methoxypyrazine | 2-iso | butyl-2-methoxypyrazine | 3-iso | butyl-2-methoxypyrazine | 2-iso | butyl-3-methoxy pyrazine | | galbanum pyrazine | 2- | methoxy 3 iso butyl pyrazine | 2 | methoxy 3 isobutylpyrazine (2-isobutyl-3-methoxypyrazine) | 2- | methoxy 3-isobutyl pyrazine | 3- | methoxy-2-isobutylpyrazine | 2- | methoxy-3-(2-methyl propyl) pyrazine | 2- | methoxy-3-(2-methylpropyl)pyrazine | 2- | methoxy-3-isobutyl pyrazine | 2- | methoxy-3-isobutyl pyrazine 1% DPG | 2- | methoxy-3-isobutylpyrazine | 2- | methoxy-3(6)-isobutyl pyrazine | 2-2- | methyl propyl-3-methoxypyrazine | | pyrazine, 2-isobutyl-3-methoxy- | | pyrazine, 2-methoxy-3-(2-methylpropyl)- | | pyrazine, 2-methoxy-3-isobutyl |
Articles:
PubMed: | Key aroma compounds in roasted in-shell peanuts. |
PubMed: | Comparison of the key aroma compounds in organically grown, raw West-African peanuts (Arachis hypogaea) and in ground, pan-roasted meal produced thereof. |
PubMed: | Growth behavior of off-flavor-forming microorganisms in apple juice. |
PubMed: | Odor thresholds of microbially induced off-flavor compounds in apple juice. |
PubMed: | Effect of cultivar and storage time on the volatile flavor components of baked potato. |
PubMed: | Characteristic aroma components of British Farmhouse Cheddar cheese. |
PubMed: | Solid-phase microextraction method development for headspace analysis of volatile flavor compounds. |
PubMed: | Electrochemical detection of the 2-isobutyl-3-methoxypyrazine model odorant based on odorant-binding proteins: The proof of concept. |
PubMed: | Dynamics of odorant binding to thin aqueous films of rat-OBP3. |
PubMed: | Identification of a specific olfactory receptor for 2-isobutyl-3-methoxypyrazine. |
PubMed: | Selectable one-dimensional or two-dimensional gas chromatography-olfactometry/mass spectrometry with preparative fraction collection for analysis of ultra-trace amounts of odor compounds. |
PubMed: | A systematic study on spatial and seasonal patterns of eight taste and odor compounds with relation to various biotic and abiotic parameters in Gonghu Bay of Lake Taihu, China. |
PubMed: | Following in their footprints: cuticular hydrocarbons as overwintering aggregation site markers in Hippodamia convergens. |
PubMed: | Simultaneous determination of ten taste and odor compounds in drinking water by solid-phase microextraction combined with gas chromatography-mass spectrometry. |
PubMed: | A methyltransferase essential for the methoxypyrazine-derived flavour of wine. |
PubMed: | The role of semiochemicals in short-range location of aggregation sites in Adalia bipunctata (Coleoptera, Coccinellidae). |
PubMed: | Defensive allomones function as aggregation pheromones in diapausing Ladybird Beetles, Hippodamia convergens. |
PubMed: | Genetic analysis of the biosynthesis of 2-methoxy-3-isobutylpyrazine, a major grape-derived aroma compound impacting wine quality. |
PubMed: | Detection and quantification of natural contaminants of wine by gas chromatography-differential ion mobility spectrometry (GC-DMS). |
PubMed: | Key aroma compounds in roasted in-shell peanuts. |
PubMed: | Behavior of 3-isobutyl-2-hydroxypyrazine (IBHP), a key intermediate in 3-isobutyl-2-methoxypyrazine (IBMP) metabolism, in ripening wine grapes. |
PubMed: | Classification of grape berries according to diameter and total soluble solids to study the effect of light and temperature on methoxypyrazine, glutathione, and hydroxycinnamate evolution during ripening of Sauvignon blanc (Vitis vinifera L.). |
PubMed: | Fruit ripening in Vitis vinifera: light intensity before and not during ripening determines the concentration of 2-methoxy-3-isobutylpyrazine in Cabernet Sauvignon berries. |
PubMed: | Occurrence of dissolved and particle-bound taste and odor compounds in Swiss lake waters. |
PubMed: | Accurate analysis of trace earthy-musty odorants in water by headspace solid phase microextraction gas chromatography-mass spectrometry. |
PubMed: | The effect of pyrazine odor on body weight and the weight of various organs in chicks (Gallus gallus domesticus). |
PubMed: | Simultaneous determination of eight common odors in natural water body using automatic purge and trap coupled to gas chromatography with mass spectrometry. |
PubMed: | Purification and characterization of two odorant-binding proteins from nasal tissue of rabbit and pig. |
PubMed: | Development of a mixed-mode solid phase extraction method and further gas chromatography mass spectrometry for the analysis of 3-alkyl-2-methoxypyrazines in wine. |
PubMed: | 2-Methoxy-3-isobutylpyrazine in grape berries and its dependence on genotype. |
PubMed: | Effect of enzyme activity and frozen storage on jalapeño pepper volatiles by selected ion flow tube-mass spectrometry. |
PubMed: | Time-resolved fluorescence spectroscopy and molecular dynamics simulations point out the effects of pressure on the stability and dynamics of the porcine odorant-binding protein. |
PubMed: | Long-timescale molecular-dynamics simulations of the major urinary protein provide atomistic interpretations of the unusual thermodynamics of ligand binding. |
PubMed: | Identification of alkyl-methoxypyrazines as the malodorous compounds in water supplies from Northwest Spain. |
PubMed: | Automated trace determination of earthy-musty odorous compounds in water samples by on-line purge-and-trap-gas chromatography-mass spectrometry. |
PubMed: | Why has porcine VEG protein unusually high stability and suppressed binding ability? |
PubMed: | Three odorant-binding proteins from rabbit nasal mucosa. |
PubMed: | Multiple types and forms of odorant-binding proteins in the Old-World porcupine Hystrix cristata. |
PubMed: | Ligand-binding properties and structural characterization of a novel rat odorant-binding protein variant. |
PubMed: | Odorant-binding proteins of the mouse. |
PubMed: | Purification and characterisation of an odorant-binding protein from cow nasal tissue. |
PubMed: | Survey of 3-alkyl-2-methoxypyrazine content of South African Sauvignon blanc wines using a novel LC-APCI-MS/MS method. |
PubMed: | Rapid measurement of 3-alkyl-2-methoxypyrazine content of winegrapes to predict levels in resultant wines. |
PubMed: | Volatile composition of Catharanthus roseus (L.) G. Don using solid-phase microextraction and gas chromatography/mass spectrometry. |
PubMed: | Structural basis of the broad specificity of a general odorant-binding protein from honeybee. |
PubMed: | Odor thresholds of microbially induced off-flavor compounds in apple juice. |
PubMed: | The molecular basis for wine grape quality--a volatile subject. |
PubMed: | Van der Waals interactions dominate ligand-protein association in a protein binding site occluded from solvent water. |
PubMed: | Removal of earthy-musty odorants in drinking water by powdered activated carbon. |
PubMed: | Effect of cultivar and storage time on the volatile flavor components of baked potato. |
PubMed: | The determination of six taste and odour compounds in water using Ambersorb 572 and high resolution mass spectrometry. |
PubMed: | Odorant and pheromone binding by aphrodisin, a hamster aphrodisiac protein. |
PubMed: | Complexes of porcine odorant binding protein with odorant molecules belonging to different chemical classes. |
PubMed: | Quantitative determination of 2-methoxy-3-isobutylpyrazine in red wines and grapes of Bordeaux using a stable isotope dilution assay. |
PubMed: | Membrane receptor for odour-binding proteins. |
PubMed: | Odorant-sensitive adenylate cyclase: rapid, potent activation and desensitization in primary olfactory neuronal cultures. |
PubMed: | Activation by odorants of a multistate cation channel from olfactory cilia. |
PubMed: | The odorant-sensitive adenylate cyclase of olfactory receptor cells. Differential stimulation by distinct classes of odorants. |
PubMed: | Isolation and characterization of an olfactory receptor protein for odorant pyrazines. |
PubMed: | A survey of seasonal temperatures and vineyard altitude influences on 2-methoxy-3-isobutylpyrazine, C13-norisoprenoids, and the sensory profile of Brazilian Cabernet Sauvignon wines. |
PubMed: | Determination of characteristic odorants from Harmonia axyridis beetles using in vivo solid-phase microextraction and multidimensional gas chromatography-mass spectrometry-olfactometry. |
PubMed: | Evidence of chemical exchange in recombinant Major Urinary Protein and quenching thereof upon pheromone binding. |
PubMed: | Influence of vine training and sunlight exposure on the 3-alkyl-2-methoxypyrazines content in musts and wines from the Vitis vinifera variety cabernet sauvignon. |
PubMed: | Thermodynamics of binding of 2-methoxy-3-isopropylpyrazine and 2-methoxy-3-isobutylpyrazine to the major urinary protein. |
PubMed: | Absolute configuration of 2-sec-butyl-4,5-dihydrothiazole in male mouse urine. |
PubMed: | Characteristic aroma components of British Farmhouse Cheddar cheese. |
PubMed: | Solid-phase microextraction method development for headspace analysis of volatile flavor compounds. |
PubMed: | Similar increases in extracellular lactic acid in the limbic system during epileptic and/or olfactory stimulation. |
PubMed: | Conformational stability and binding properties of porcine odorant binding protein. |
PubMed: | Subtypes of odorant-binding proteins--heterologous expression and ligand binding. |
PubMed: | Lipocalins of boar salivary glands binding odours and pheromones. |
PubMed: | Isolation of two odorant-binding proteins from mouse nasal tissue. |
PubMed: | Ligand binding characteristics of homologous rat and mouse urinary proteins and pyrazine-binding protein of calf. |
PubMed: | Ultrastructural characteristics of sustentacular cells in control and odorant-treated olfactory mucosae of the salamander. |
PubMed: | Odorant stimulation of secretory and neural processes in the salamander olfactory mucosa. |
PubMed: | Immunocytochemical localization of pyrazine-binding protein in bovine nasal mucosa. |
PubMed: | Occurrence of a pyrazine binding protein in the nasal mucosa of some vertebrates. |
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