2-methyl-3-furyl tetrasulfide
bis(2-methyl-3-furyl) tetrasulfide
 
Notes:
Flavouring agent for meat products and baked goods
  • Beijing Lys Chemicals
    • Beijing Lys Chemicals Co, LTD.
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      BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services.
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      10264 Bis(2-Methyl-3-furyl)tetrasulfide
       
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      Product(s):
      28588-76-3 Bis(2-methyl-3-furyl)tetrasulfide
       
  • M&U International
    • M&U International LLC
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      A0343 Bis(2-METHYL-3-FURYL) TETRASULFIDE, Kosher
       
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CAS Number: 28588-76-3Picture of molecule3D/inchi
FDA UNII: 1DAG9X2ID7
Nikkaji Web: J130.142J
CoE Number: 724
XlogP3-AA: 3.80 (est)
Molecular Weight: 290.44810000
Formula: C10 H10 O2 S4
NMR Predictor: Predict (works with chrome, Edge or firefox)
Category: flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
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NCBI: Search
JECFA Food Flavoring: 1068  bis(2-methyl-3-furyl) tetrasulfide
DG SANTE Food Flavourings: 13.017  bis(2-methyl-3-furyl) tetrasulfide
FEMA Number: 3260 bis(2-methyl-3-furyl) tetrasulfide
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):28588-76-3 ; BIS(2-METHYL-3-FURYL) TETRASULFIDE
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Physical Properties:
Appearance: yellow clear liquid (est)
Assay: 96.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 1.36600 to 1.37800 @  25.00 °C.
Pounds per Gallon - (est).: 11.366 to 11.466
Refractive Index: 1.67100 to 1.69300 @  20.00 °C.
Boiling Point: 142.00 to  147.00 °C. @ 0.80 mm Hg
Boiling Point: 396.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.000003 mmHg @ 25.00 °C. (est)
Flash Point: 147.00 °F. TCC ( 63.89 °C. )
logP (o/w): 6.708 (est)
Soluble in:
 alcohol
 water, 4.06 mg/L @ 25 °C (est)
Insoluble in:
 water
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Organoleptic Properties:
 
Odor Type: sulfurous
 
 sulfurous  meaty  
Odor Description:
at 0.10 % in propylene glycol. 
sulfury meaty
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Beijing Lys Chemicals
Bis(2-Methyl-3-furyl)tetrasulfide
BOC Sciences
For experimental / research use only.
Bis(2-methyl-3-furyl)tetrasulfide
M&U International
Bis(2-METHYL-3-FURYL) TETRASULFIDE, Kosher
Parchem
2-methyl-3-furyl tetrasulfide
Penta International
BIS(2-METHYL-3-FURYL) TETRASULFIDE
WholeChem
Bis(2-methyl-3-furyl)tetrasulfide
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
gavage-mouse LD50  [sex: M,F] 220 mg/kg
(Oser, 1970c)

gavage-mouse LD50  [sex: M,F] 220 mg/kg
(Moran et al., 1980)

oral-mouse LD50  220 mg/kg
Drug and Chemical Toxicology. Vol. 3, Pg. 249, 1980.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavoring agents
Recommendation for 2-methyl-3-furyl tetrasulfide usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.97 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.70 (μg/capita/day)
Structure Class: III
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 5
Click here to view publication 5
 average usual ppmaverage maximum ppm
baked goods: -0.10000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: -0.10000
cheese: --
chewing gum: --
condiments / relishes: -0.10000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: -0.10000
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -0.10000
milk products: -0.10000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: -0.10000
sugar substitutes: --
sweet sauces: --
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Safety References:
European Food Safety Athority(EFSA): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 13 (FGE.13); Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 (Commission Regulation (EC) No 1565/2000 of 18
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 13Rev1: Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14
View page or View pdf
Consideration of sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of “Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14” evaluated by EFSA in FGE.13Rev1 (2009)
View page or View pdf
Flavouring Group Evaluation 67 (FGE.67): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 13, Revision 2 (FGE.13Rev2): Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 67, Revision 1 (FGE.67Rev.1): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 65, Revision 1 (FGE.65Rev1): Consideration of sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of ‘Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14’ evaluated by EFSA in FGE.13Rev2 (2011)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 13 Revision 3 (FGE.13Rev3): furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14
View page or View pdf
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EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 24832089
National Institute of Allergy and Infectious Diseases: Data
 2-methyl-3-[(2-methyl-3-furyl)disulfanyldisulfanyl]furan
Chemidplus: 0028588763
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References:
 2-methyl-3-[(2-methyl-3-furyl)disulfanyldisulfanyl]furan
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 28588-76-3
Pubchem (cid): 24832089
Pubchem (sid): 135280364
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
HMDB (The Human Metabolome Database): HMDB36168
FooDB: FDB015022
Export Tariff Code: 2932.19.0000
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
EFSA Update of results on the monitoring of furan levels in food: Read Report
EFSA Previous report: Results on the monitoring of furan levels in food: Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food: Read Report
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Potential Blenders and core components note
 
For Odor
coffee
coffee
 coffee difuranFL/FR
floral
6,8-dimethyl-2-nonanolFR
meaty
 meaty dithianeFL/FR
4-methyl nonanoic acidFL/FR
 fish thiolFL/FR
2-mercaptopropionic acidFL/FR
4-methyl 4-mercaptopentan-2-one 1% solutionFL/FR
 
For Flavor
 
No flavor group found for these
 benzyl methyl sulfideFL
 ethyl 4-(acetyl thio) butyrateFL
4-methyl 4-mercaptopentan-2-one 1% solutionFL/FR
1,9-nonane dithiolFL
1,3-propane dithiolFL
isopropyl disulfideFL
alliaceous
1,3-butane dithiolFL
coffee
 coffee difuranFL/FR
corn chip
2-acetyl-2-thiazolineFL
earthy
 difurfuryl sulfideFL
1,8-octane dithiolFL
eggy
isopropyl mercaptanFL
fatty
4-methyl nonanoic acidFL/FR
2,4-octadien-1-olFL
green
4-penten-1-yl acetateFL
meaty
2,6-dimethyl thiophenolFL
2,5-dimethyl-3-furan thiolFL
 meaty dithianeFL/FR
2-mercaptopropionic acidFL/FR
S-(2-methyl-3-furyl) ethane thioateFL
2-methyl-3-tetrahydrofuran thiolFL
 pyrazinyl ethane thiolFL
ortho-thiocresolFL
metallic
2,5-dihydroxy-1,4-dithianeFL
nutty
 nutty thiazoleFL
roasted
 hexyl mercaptanFL
sulfurous
2,3-butane dithiolFL
 fish thiolFL/FR
 methyl 2-methyl-3-furyl disulfideFL
 roasted butanolFL
 
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Potential Uses:
 chickenFL
 meatFL
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Occurrence (nature, food, other): note
 meat boiled meat
Search  PMC Picture
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Synonyms:
 furan, 3,3'-(1,4-tetrasulfanediyl)bis[2-methyl-
2-methyl-3-[(2-methyl-3-furyl)disulfanyldisulfanyl]furan
bis(2-methyl-3-furyl) tetrasulfide
bis(2-methyl-3-furyl)tetrasulfide
3,3'-(1,4-tetrasulfanediyl)bis[2-methylfuran]
3,3-tetrathiobis(2-methyl furan)
3,3'-tetrathiobis[2-methylfuran]
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