Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | yellow clear liquid (est) |
Assay: | 96.00 to 100.00 %
|
Food Chemicals Codex Listed: | No |
Specific Gravity: | 1.36600 to 1.37800 @ 25.00 °C.
|
Pounds per Gallon - (est).: | 11.366 to 11.466
|
Refractive Index: | 1.67100 to 1.69300 @ 20.00 °C.
|
Boiling Point: | 142.00 to 147.00 °C. @ 0.80 mm Hg
|
Boiling Point: | 396.00 °C. @ 760.00 mm Hg
|
Vapor Pressure: | 0.000003 mmHg @ 25.00 °C. (est) |
Flash Point: | 147.00 °F. TCC ( 63.89 °C. )
|
logP (o/w): | 6.708 (est) |
Soluble in: |
| alcohol | | water, 4.06 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
|
Odor Type: sulfurous |
|
| sulfurous meaty |
Odor Description: at 0.10 % in propylene glycol. | sulfury meaty |
|
Odor and/or flavor descriptions from others (if found). |
|
|
Cosmetic Information:
Suppliers:
Safety Information:
|
Hazards identification |
|
Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
|
Pictogram | |
|
Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
gavage-mouse LD50 [sex: M,F] 220 mg/kg (Oser, 1970c)
gavage-mouse LD50 [sex: M,F] 220 mg/kg (Moran et al., 1980)
oral-mouse LD50 220 mg/kg Drug and Chemical Toxicology. Vol. 3, Pg. 249, 1980.
|
Dermal Toxicity: |
Not determined
|
Inhalation Toxicity: |
Not determined
|
Safety in Use Information:
Category: | flavoring agents |
Recommendation for 2-methyl-3-furyl tetrasulfide usage levels up to: | | not for fragrance use.
|
|
Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.97 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.70 (μg/capita/day) |
Structure Class: | III |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 5 |
Click here to view publication 5 |
| average usual ppm | average maximum ppm |
baked goods: | - | 0.10000 |
beverages(nonalcoholic): | - | - |
beverages(alcoholic): | - | - |
breakfast cereal: | - | 0.10000 |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | 0.10000 |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | - |
fruit ices: | - | - |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | 0.10000 |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | 0.10000 |
milk products: | - | 0.10000 |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | 0.10000 |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 13 (FGE.13); Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 (Commission Regulation (EC) No 1565/2000 of 18 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 13Rev1: Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 View page or View pdf |
Consideration of sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of “Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14” evaluated by EFSA in FGE.13Rev1 (2009) View page or View pdf |
Flavouring Group Evaluation 67 (FGE.67): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 13, Revision 2 (FGE.13Rev2): Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 67, Revision 1 (FGE.67Rev.1): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 65, Revision 1 (FGE.65Rev1): Consideration of sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of ‘Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14’ evaluated by EFSA in FGE.13Rev2 (2011) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 13 Revision 3 (FGE.13Rev3): furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 24832089 |
National Institute of Allergy and Infectious Diseases: | Data |
| 2-methyl-3-[(2-methyl-3-furyl)disulfanyldisulfanyl]furan |
Chemidplus: | 0028588763 |
References:
Other Information:
Potential Blenders and core components note
|
For Odor |
coffee |
coffee |
| coffee difuran | FL/FR |
floral |
6,8- | dimethyl-2-nonanol | FR |
meaty |
| meaty dithiane | FL/FR |
4- | methyl nonanoic acid | FL/FR |
| fish thiol | FL/FR |
2- | mercaptopropionic acid | FL/FR |
4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
|
For Flavor |
|
No flavor group found for these |
| benzyl methyl sulfide | FL |
| ethyl 4-(acetyl thio) butyrate | FL |
4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
1,9- | nonane dithiol | FL |
1,3- | propane dithiol | FL |
iso | propyl disulfide | FL |
alliaceous |
1,3- | butane dithiol | FL |
coffee |
| coffee difuran | FL/FR |
corn chip |
2- | acetyl-2-thiazoline | FL |
earthy |
| difurfuryl sulfide | FL |
1,8- | octane dithiol | FL |
eggy |
iso | propyl mercaptan | FL |
fatty |
4- | methyl nonanoic acid | FL/FR |
2,4- | octadien-1-ol | FL |
green |
4- | penten-1-yl acetate | FL |
meaty |
2,6- | dimethyl thiophenol | FL |
2,5- | dimethyl-3-furan thiol | FL |
| meaty dithiane | FL/FR |
2- | mercaptopropionic acid | FL/FR |
S-(2- | methyl-3-furyl) ethane thioate | FL |
2- | methyl-3-tetrahydrofuran thiol | FL |
| pyrazinyl ethane thiol | FL |
ortho- | thiocresol | FL |
metallic |
2,5- | dihydroxy-1,4-dithiane | FL |
nutty |
| nutty thiazole | FL |
roasted |
| hexyl mercaptan | FL |
sulfurous |
2,3- | butane dithiol | FL |
| fish thiol | FL/FR |
| methyl 2-methyl-3-furyl disulfide | FL |
| roasted butanol | FL |
|
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| furan, 3,3'-(1,4-tetrasulfanediyl)bis[2-methyl- | 2- | methyl-3-[(2-methyl-3-furyl)disulfanyldisulfanyl]furan | bis(2- | methyl-3-furyl) tetrasulfide | bis(2- | methyl-3-furyl)tetrasulfide | 3,3'-(1,4- | tetrasulfanediyl)bis[2-methylfuran] | 3,3- | tetrathiobis(2-methyl furan) | 3,3'- | tetrathiobis[2-methylfuran] |
Articles:
|