PubMed: | Preliminary In Vitro and In Vivo Evaluation of Antidiabetic Activity of Ducrosia anethifolia Boiss. and Its Linear Furanocoumarins. |
PubMed: | Potential drug interactions with melatonin. |
PubMed: | Application of the equivalency factor concept to the phototoxicity and -genotoxicity of furocoumarin mixtures. |
PubMed: | Quantification and repair of psoralen-induced interstrand crosslinks in human cells. |
PubMed: | [Simultaneous determination of eight furocoumarines in cosmetics by high performance liquid chromatography and verification by liquid chromatography-tandem mass spectrometry]. |
PubMed: | Contamination of deconjugation enzymes derived from Helix pomatia with the plant bioactive compounds 3,3'-diindolylmethane, 5-methoxypsoralen, and 8-methoxypsoralen. |
PubMed: | Pharmacokinetic studies of bergapten in dog plasma by using a LC-MS/MS method studies. |
PubMed: | Simultaneous determination of scopoletin, psoralen, bergapten, xanthotoxin, columbianetin acetate, imperatorin, osthole and isoimperatorin in rat plasma by LC-MS/MS for pharmacokinetic studies following oral administration of Radix Angelicae Pubescentis extract. |
PubMed: | Bergapten induces ER depletion in breast cancer cells through SMAD4-mediated ubiquitination. |
PubMed: | Chemical composition of hexane extract of Citrus aurantifolia and anti-Mycobacterium tuberculosis activity of some of its constituents. |
PubMed: | Antagonistic regulation, yet synergistic defense: effect of bergapten and protease inhibitor on development of cowpea bruchid Callosobruchus maculatus. |
PubMed: | Effect of polyamines on shoot multiplication and furanocoumarin production in Ruta graveolens cultures. |
PubMed: | A new sphingolipid and furanocoumarins with antimicrobial activity from Ficus exasperata. |
PubMed: | [Chemical constituents contained in seeds of Notopterygium franchetii]. |
PubMed: | Protective effects of 5-methoxypsoralen against acetaminophen-induced hepatotoxicity in mice. |
PubMed: | [Phamacokinetic study of bergapten in rats plasma by LC-MS/MS]. |
PubMed: | An investigation of the catalytic activity of CYP2A13*4 with coumarin and polymorphisms of CYP2A13 in a Chinese Han population. |
PubMed: | Structure-activity relationships for naturally occurring coumarins as Ī²-secretase inhibitor. |
PubMed: | Major furocoumarins in grapefruit juice II: phototoxicity, photogenotoxicity, and inhibitory potency vs. cytochrome P450 3A4 activity. |
PubMed: | Flu-like syndrome, bronchoconstriction and fever caused by 5-methoxypsoralen: the first case report and literature review. |
PubMed: | Efficacy of psoralen plus ultraviolet A therapy vs. biologics in moderate to severe chronic plaque psoriasis: retrospective data analysis of a patient registry. |
PubMed: | Percutaneous penetration of 5-methoxypsoralen in rhesus monkeys. |
PubMed: | Anticonvulsant effects of four linear furanocoumarins, bergapten, imperatorin, oxypeucedanin, and xanthotoxin, in the mouse maximal electroshock-induced seizure model: a comparative study. |
PubMed: | Immunotoxicity activity of natural furocoumarins from milky sap of Ficus carica L. against Aedes aegypti L. |
PubMed: | Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function. |
PubMed: | [High-performance liquid chromatography for determination of psoralene, bergapten and apigenin in Ficus hirta Vahl]. |
PubMed: | The effects of single nucleotide polymorphisms in CYP2A13 on metabolism of 5-methoxypsoralen. |
PubMed: | In vitro photo-induced cytotoxic activity of Citrus bergamia and C. medica L. cv. Diamante peel essential oils and identified active coumarins. |
PubMed: | Erythroid induction of chronic myelogenous leukemia K562 cells following treatment with a photoproduct derived from the UV-A irradiation of 5-methoxypsoralen. |
PubMed: | Caffeine as a photoprotective agent for diminishing phototoxicity. |
PubMed: | Photoallergic contact dermatitis to 8-methoxypsoralen in Ficus carica. |
PubMed: | Biotransformation of bergapten and xanthotoxin by Glomerella cingulata. |
PubMed: | Antimicrobial coumarins from the stem bark of Afraegle paniculata. |
PubMed: | Rapid characterization of cross-links, mono-adducts, and non-covalent binding of psoralens to deoxyoligonucleotides by LC-UV/ESI-MS and IRMPD mass spectrometry. |
PubMed: | Breast cancer cell survival signal is affected by bergapten combined with an ultraviolet irradiation. |
PubMed: | Simultaneous and sensitive determination of xanthotoxin, psoralen, isoimpinellin and bergapten in rat plasma by liquid chromatography-electrospray ionization mass spectrometry. |
PubMed: | Psoralen and bergapten: in silico metabolism and toxicophoric analysis of drugs used to treat vitiligo. |
PubMed: | Application of the concept of relative photomutagenic potencies to selected furocoumarins in V79 cells. |
PubMed: | 5-Methoxypsoralen plus ultraviolet (UV) A is superior to medium-dose UVA1 in the treatment of severe atopic dermatitis: a randomized crossover trial. |
PubMed: | Furanocoumarins: novel topoisomerase I inhibitors from Ruta graveolens L. |
PubMed: | Relative photomutagenicity of furocoumarins and limettin in the hypoxanthine phosphoribosyl transferase assay in V79 cells. |
PubMed: | Modulation of expression of IL-8 gene in bronchial epithelial cells by 5-methoxypsoralen. |
PubMed: | [Tyrosinase inhibitor from Angelica dahurica roots]. |
PubMed: | Effect of bergapten from Heracleum nepalense root on production of proinflammatory cytokines. |
PubMed: | Evidence that bergapten, independently of its photoactivation, enhances p53 gene expression and induces apoptosis in human breast cancer cells. |
PubMed: | Botanical origin of Indian celery seed (fruit). |
PubMed: | Time course for development of psoralen plus ultraviolet A erythema following oral administration of 5-methoxypsoralen. |
PubMed: | [Chemical constituents of antibacterial activity fraction of Angelica polymorpha]. |
PubMed: | Extraction of antioxidants from plants using ultrasonic methods and their antioxidant capacity. |
PubMed: | 4-Phenoxybutoxy-substituted heterocycles--a structure-activity relationship study of blockers of the lymphocyte potassium channel Kv1.3. |
PubMed: | Constitutive expression of bergaptol O-methyltransferase in Glehnia littoralis cell cultures. |
PubMed: | [Contents of furanocoumarins in grapefruit juice and health foods]. |
PubMed: | Coumarin, anthroquinone and stilbene derivatives with anticholinesterase activity. |
PubMed: | Isolation and identification of insecticidal components from Citrus aurantium fruit peel extract. |
PubMed: | Lipid nanoparticles as vehicles for topical psoralen delivery: solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC). |
PubMed: | Bioassay directed identification of natural aryl hydrocarbon-receptor agonists in marmalade. |
PubMed: | Furocoumarins photolysis products induce differentiation of human erythroid cells. |
PubMed: | Real-time fluorescence-based detection of furanocoumarin photoadducts of DNA. |
PubMed: | In vitro antiplasmodial activity of extract and constituents from Esenbeckia febrifuga, a plant traditionally used to treat malaria in the Brazilian Amazon. |
PubMed: | [Simultaneous determination of 8-methoxypsoralen and 5-methoxypsoralen in cosmetics using LC-MS/MS]. |
PubMed: | Identification of Ruta graveolens L. metabolites accumulated in the presence of abiotic elicitors. |
PubMed: | [Simultaneous determination of 5 active components in Fructus Cnidii by HPLC]. |
PubMed: | Central role of mitochondria and p53 in PUVA-induced apoptosis in human keratinocytes cell line NCTC-2544. |
PubMed: | Induction of gamma-globin mRNA, erythroid differentiation and apoptosis in UVA-irradiated human erythroid cells in the presence of furocumarin derivatives. |
PubMed: | Inhibition on human liver cytochrome P450 3A4 by constituents of fennel (Foeniculum vulgare): identification and characterization of a mechanism-based inactivator. |
PubMed: | Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts. |
PubMed: | Constituents, biological activities and quality control parameters of the crude extract and essential oil from Arracacia tolucensis var. multifida. |
PubMed: | Coumarins from Peucedanum luxurians. |
PubMed: | Antimicrobial activity of the methanolic extracts and compounds from Treculia obovoidea (Moraceae). |
PubMed: | [Studies on chemical constituents from fruits of Paliurus ramosissimus]. |
PubMed: | Burns caused by accidental overdose of photochemotherapy (PUVA). |
PubMed: | Solar simulator-induced phototoxicity of the furoquinoline alkaloid dictamnine compared to 8-methoxypsoralen and 5-methoxypsoralen. |
PubMed: | Simultaneous determination of urinary metabolites of methoxypsoralens in human and Umbelliferae medicines by high-performance liquid chromatography. |
PubMed: | Variations in content of active ingredients causing drug interactions in grapefruit juice products sold in California. |
PubMed: | Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1. |
PubMed: | A method for quantitative determination of furanocoumarins in capsules and tablets of phytochemical preparations. |
PubMed: | Phototoxicity of new psoralen-containing gels and creams versus bath PUVA. |
PubMed: | Use of the yeast Saccharomyces cerevisiae as a pre-screening approach for assessment of chemical-induced phototoxicity. |
PubMed: | Efficacy of 8-methoxypsoralen vs. 5-methoxypsoralen plus ultraviolet A therapy in patients with mycosis fungoides. |
PubMed: | Effects of 5-methoxypsoralen (5-MOP) on arylamine N-acetyltransferase activity in the stomach and colon of rats and human stomach and colon tumor cell lines. |
PubMed: | 5-(3-Phenylpropoxy)psoralen and 5-(4-phenylbutoxy)psoralen: mechanistic studies on phototoxicity. |
PubMed: | Antioxidant activity of citrus limonoids, flavonoids, and coumarins. |
PubMed: | [Study on coumarin compounds from Exocarpium Citri Grandis]. |
PubMed: | 2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica. |
PubMed: | Preparative isolation and purification of bergapten and imperatorin from the medicinal plant Cnidium monnieri using high-speed counter-current chromatography by stepwise increasing the flow-rate of the mobile phase. |
PubMed: | Phototoxicity of protoporphyrin IX, diarginine diprotoporphyrinate and N,N-diphenylalanyl protoporphyrin toward human fibroblasts and keratinocytes in vitro: effect of 5-methoxypsoralen. |
PubMed: | Genetic variation in primary metabolites of Pastinaca sativa; can herbivores act as selective agents? |
PubMed: | A method for fast determination of psoralens in oral solutions of phytomedicines using liquid chromatography. |
PubMed: | Inhibition of DNA polymerization and antifungal specificity of furanocoumarins present in traditional medicines. |
PubMed: | Synthesis and photocytotoxic activity of new alpha-methylene-gamma-butyrolactone-psoralen heterodimers. |
PubMed: | Phytotoxins from the leaves of Ruta graveolens. |
PubMed: | Furanocoumarin biosynthesis in Ammi majus L. Cloning of bergaptol O-methyltransferase. |
PubMed: | The furanocoumarins in the roots of Heracleum sibiricum L. |
PubMed: | Theoretical study on the excited states of psoralen compounds bonded to a thymine residue. |
PubMed: | Markovian chemicals "in silico" design (MARCH-INSIDE), a promising approach for computer-aided molecular design I: discovery of anticancer compounds. |
PubMed: | Molecular docking of substrates and inhibitors in the catalytic site of CYP6B1, an insect cytochrome p450 monooxygenase. |
PubMed: | Effect of 5-methoxypsoralen (5-MOP) on cell apoptosis and cell cycle in human hepatocellular carcinoma cell line. |
PubMed: | Reproductive toxicity of the psoralens. |
PubMed: | Skin permeation of 5-methoxypsoralen from topical dosage forms. |
PubMed: | In vitro and in vivo study of 5-methoxypsoralen skin concentration after topical application. |
PubMed: | Rodenticidal activity of two natural coumarines from ether extract of Citrus bergamia. |
PubMed: | [Studies on chemical constituents of Peucedanum medium Dunn var. garcile Dunn ex Shan at Sheh]. |
PubMed: | Effect of psoralens on Fenton-like reaction generating reactive oxygen species. |
PubMed: | Validation of a microdialysis-gas chromatographic-mass spectrometric method to assess 8-methoxypsoralen in psoriatic patient dermis. |
PubMed: | Determination of 5-methoxypsoralen in human serum. |
PubMed: | In vivo effect of 5- and 8-methoxypsoralens and cimetidine on R,S-warfarin metabolism in rat. |
PubMed: | Tea: not immoral, illegal, or fattening, but is it innocuous? |
PubMed: | Oral administration of 5-methoxypsoralen affects the distribution and metabolism of 2-aminofluorene in Sprague-Dawley rats. |
PubMed: | Zabon phytophotodermatitis: first case reports due to Citrus maxima. |
PubMed: | Amino acids in SRS1 and SRS6 are critical for furanocoumarin metabolism by CYP6B1v1, a cytochrome P450 monooxygenase. |
PubMed: | Effects of storage conditions on furocoumarin levels in intact, chopped, or homogenized parsnips. |
PubMed: | Chalcones and other constituents of Dorstenia prorepens and Dorstenia zenkeri. |
PubMed: | Simultaneous determination of furanocoumarins in infusions and decoctions from "CarapiĆ”" (dorstenia species) by high-performance liquid chromatography. |
PubMed: | Photosensitization and mutation induced in Escherichia coli and Saccharomyces cerevisiae strains by dorstenin, a psoralen analog isolated from Dorstenia bahiensis. |
PubMed: | Inhibition of human CYP3A4 activity by grapefruit flavonoids, furanocoumarins and related compounds. |
PubMed: | Anaphylaxis to 5-methoxypsoralen during photochemotherapy. |
PubMed: | Simple and rapid determination of psoralens in topic solutions using liquid chromatography. |
PubMed: | Indolopyridoquinazoline alkaloid from Leptothyrsa sprucei. |
PubMed: | Effects of silperisone on the excitation process in Ranvier nodes. |
PubMed: | Accidental bullous phototoxic reactions to bergamot aromatherapy oil. |
PubMed: | Plasma and skin concentration of 5-methoxypsoralen in psoriatic patients after oral administration. |
PubMed: | Furanocoumarins in celery and parsnips: method and multiyear Canadian survey. |
PubMed: | Effects of three alkoxypsoralens on voltage gated ion channels in Ranvier nodes. |
PubMed: | The psoralens adversely affect reproductive function in male wistar rats. |
PubMed: | Development of a highly sensitive in vitro phototoxicity assay using the SkinEthic reconstructed human epidermis. |
PubMed: | [Heracl'eum mantegazzi'anum: photosensitization]. |
PubMed: | Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins. |
PubMed: | Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4. |
PubMed: | Dietary psoralens induce hepatotoxicity in C57 mice. |
PubMed: | K(+) channel-blocking alkoxypsoralens inhibit the immune response of encephalitogenic T line cells and lymphocytes from Lewis rats challenged for experimental autoimmune encephalomyelitis. |
PubMed: | Content of CYP3A4 inhibitors, naringin, naringenin and bergapten in grapefruit and grapefruit juice products. |
PubMed: | Generalised granuloma annulare successfully treated with PUVA. |
PubMed: | Hepatitis from 5-methoxypsoralen occurring in a patient with previous flucloxacillin hepatitis. |
PubMed: | Carcinogenic risk of bath PUVA in comparison to oral PUVA therapy. |
PubMed: | New tetracyclic analogues of photochemotherapeutic drugs 5-MOP and 8-MOP: synthesis, DNA interaction, and antiproliferative activity. |
PubMed: | Measurement of 5-methoxypsoralen and 8-methoxypsoralen in saliva of PUVA patients as a noninvasive, clinically relevant alternative to monitoring in blood. |
PubMed: | [Bullous phototoxic contact dermatitis caused by Ruta graveolens L. (garden rue), Rutaceae. Case report and review of literature]. |
PubMed: | Examination of psoralens-induced photodermatitis in Wistar rats under scanning electron microscopy. |
PubMed: | A novel group of ovarian toxicants: the psoralens. |
PubMed: | 5-Methoxypsoralen. A review of its effects in psoriasis and vitiligo. |
PubMed: | Mechanism-based inactivation of cytochrome P450 2B1 by 8-methoxypsoralen and several other furanocoumarins. |
PubMed: | Psoralens in association with seasonal affective disorder. |
PubMed: | Phototoxic contact dermatitis from 5-methoxypsoralen in aromatherapy oil. |
PubMed: | Mechanism-based inactivation of P450 2A6 by furanocoumarins. |
PubMed: | Induction of furanocoumarin biosynthesis in Glehnia littoralis cell suspension cultures by elicitor treatment. |
PubMed: | Triple helix-directed psoralen crosslinks are recognized by Uvr(A)BC excinuclease. |
PubMed: | PUVA-induced cell mortality in NCTC 2544 keratinocytes: is it related to the microenvironmental properties of the excited states of psoralens? |
PubMed: | Antiproliferative activity and phototoxicity of some methyl derivatives of 5-methoxypsoralen and 5-methoxyangelicin. |
PubMed: | High-performance thin-layer chromatographic determination of 5-methoxypsoralen in serum from patients. |
PubMed: | Some new methyl-8-methoxypsoralens: synthesis, photobinding to DNA, photobiological properties and molecular modelling. |
PubMed: | Bath-5-methoxypsoralen-UVA therapy for psoriasis. |
PubMed: | Isolation and characterization of CYP6B4, a furanocoumarin-inducible cytochrome P450 from a polyphagous caterpillar (Lepidoptera:papilionidae). |
PubMed: | Studies on the photobiological activity of two naturally occurring furochromones, visnagin and khellin, in Chlamydomonas reinhardtii. |
PubMed: | Spectrofluorimetric determination of 5-methoxypsoralen pharmacokinetic in patients' serum. |
PubMed: | Psoralen-induced growth inhibition in Wistar rats. |
PubMed: | Specific inhibition of cyclic AMP-dependent protein kinase by warangalone and robustic acid. |
PubMed: | Photoprotection by furocoumarin-induced melanogenesis against DNA photodamage in mouse epidermis in vivo. |
PubMed: | Topical or oral administration with an extract of Polypodium leucotomos prevents acute sunburn and psoralen-induced phototoxic reactions as well as depletion of Langerhans cells in human skin. |
PubMed: | Psoralens percutaneous permeation across the human whole skin and the epidermis in respect to their polarity (in vitro study). |
PubMed: | Isolation and identification of antimicrobial furocoumarins from parsley. |
PubMed: | Ergotism and photosensitization in swine produced by the combined ingestion of Claviceps purpurea sclerotia and Ammi majus seeds. |
PubMed: | 4'-Methyl derivatives of 5-MOP and 5-MOA: synthesis, photoreactivity, and photobiological activity. |
PubMed: | [Dermatitis bullosa striata pratensis caused by Dictamnus albus L. (burning bush)]. |
PubMed: | Incidence and in-vivo relevance of anti-interferon antibodies during treatment of low-grade cutaneous T-cell lymphomas with interferon alpha-2a combined with acitretin or PUVA. |
PubMed: | Photoaccentuated erythroderma associated with CD4+ T lymphocytopenia: successful treatment with 5-methoxypsoralen and UVA, interferon alfa-2b, and extracorporeal photopheresis. |
PubMed: | Inhibitors of CYP6D1 in house fly microsomes. |
PubMed: | PUVA (5-methoxypsoralen plus UVA) enhances melanogenesis and modulates expression of melanogenic proteins in cultured melanocytes. |
PubMed: | Inhibition of caffeine metabolism by 5-methoxypsoralen in patients with psoriasis. |
PubMed: | Lipophilicity determination of psoralens used in therapy through solubility and partitioning: comparison of theoretical and experimental approaches. |
PubMed: | Isopimpinellin is not phototoxic in a chick skin assay. |
PubMed: | Photoreaction of 5-methoxypsoralen with thymidine and the thymine moiety of isolated and Saccharomyces cerevisiae DNA. Characterization and measurement of the two cis-syn furan-side monocycloadducts. |
PubMed: | 5-Methoxypsoralen photoadduct formation: conversion of monoadducts to crosslinks. |
PubMed: | Melanoma and use of sunscreens: an Eortc case-control study in Germany, Belgium and France. The EORTC Melanoma Cooperative Group. |
PubMed: | Ultraviolet A-induced photodegradation of 5-methoxypsoralen, 8-methoxypsoralen and psoralen reduces the biological effectiveness of the furocoumarins in vivo. |
PubMed: | Photoreaction of 5-methoxypsoralen with thymidine. Isolation and characterization of a pyrone-side monoadduct involving the pyrimidine methyl group. |
PubMed: | Antidepressant effect of 5-methoxypsoralen: The melatonin synchronizer hypothesis. |
PubMed: | Acquired persistent atypical lentigines as a failure of 5-methoxypsoralen-containing sunscreens in the photochemoprotection from ultraviolet-radiation-induced damage. |
PubMed: | 5-Methoxypsoralen inhibits 6-hydroxylation of melatonin in the rat. |
PubMed: | Methoxypsoralen phototherapy of transitional cell carcinoma. |
PubMed: | Potential allelochemicals fromRuta graveolens L. and their action on radish seeds. |
PubMed: | The time of onset and duration of 5-methoxypsoralen photochemoprotection from UVR-induced DNA damage in human skin. |
PubMed: | Treatment of psoriasis with psoralens and ultraviolet A. A double-blind comparison of 8-methoxypsoralen and 5-methoxypsoralen. |
PubMed: | Induction of the genes RAD54 and RNR2 by various DNA damaging agents in Saccharomyces cerevisiae. |
PubMed: | Chromosome damage in PUVA-treated human lymphocytes is related to active oxygen species and clastogenic factors. |
PubMed: | Transcriptional regulation of the Papilio polyxenes CYP6B1 gene. |
PubMed: | The complement activation assay: The test for immediate phototoxicity. |
PubMed: | [Chronobiology and depression: the seasonal depressions. Clinical aspects, physiopathology and specific treatments]. |
PubMed: | Mode of action of psoralens, benzofurans, acridinons, and coumarins on the ionic currents in intact myelinated nerve fibres and its significance in demyelinating diseases. |
PubMed: | Regulation of melanogenesis induced by 5-methoxypsoralen without ultraviolet light in murine melanoma cells. |
PubMed: | Quantitative assessment of epidermal melanogenesis in C3H/Tif hr/hr mice treated with topical furocoumarins and UVA radiation. |
PubMed: | Rapid identification of some coumarin derivatives in deterpenated citrus peel oil by gas chromatography. |
PubMed: | Effects of a new psoralen, 5-geranoxypsoralen, plus UVA radiation on murine ATPase positive Langerhans cells. |
PubMed: | Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting. |
PubMed: | British Photodermatology Group guidelines for PUVA. |
PubMed: | Treatment of psoriasis with a new micronized 5-methoxypsoralen tablet and UVA radiation. |
PubMed: | Food-induced increase in bioavailability of 5-methoxypsoralen. |
PubMed: | Induction of cytochrome P-450 by 5-methoxypsoralen in the yeast Saccharomyces cerevisiae. |
PubMed: | Characterization of the cis-syn and cis-anti diastereoisomers of 5-methoxypsoralen pyrone-side monocycloadducts to thymidine. |
PubMed: | Activation of the human immunodeficiency virus promoter by UVA radiation in combination with psoralens or angelicins. |
PubMed: | Blocking of potassium channels in Ranvier nodes by 4,5,6,7-substituted benzofurans and its significance on demyelinating diseases. |
PubMed: | [Long-term effect of psoralens?]. |
PubMed: | Differential inhibition of coumarin 7-hydroxylase activity in mouse and human liver microsomes. |
PubMed: | DNA damage in UV-irradiated human skin in vivo: automated direct measurement by image analysis (thymine dimers) compared with indirect measurement (unscheduled DNA synthesis) and protection by 5-methoxypsoralen. |
PubMed: | Skin concentration of 8-methoxypsoralen, 5-methoxypsoralen and 4,5,8-trimethylpsoralen in guinea pigs. |
PubMed: | Serum free 5-methoxypsoralen fraction in health and psoriasis: relationship with human serum albumin concentration. |
PubMed: | [Isolation and structure elucidation of qianhucoumarin A]. |
PubMed: | 5-Methoxypsoralen: effect on the noradrenaline circadian rhythm of sleep-deprived subjects. |
PubMed: | Evaluation of phototoxic and photogenotoxic risk associated with the use of photosensitizers in suntan preparations: application to tanning preparations containing bergamot oil. |
PubMed: | Binding of 5-methoxypsoralen to blood fractions. Influence of albumin and free fatty acids: an in vitro study. |
PubMed: | Sequence specificity of psoralen photobinding to DNA: a quantitative approach. |
PubMed: | Metabolism of the anti-psoriatic agent 5-methoxypsoralen in humans: comparison with rat and dog. |
PubMed: | Expression of cytochrome P450 in yeast after different chemical treatments. |
PubMed: | 8-MOP vs 5-MOP. |
PubMed: | Psoralens cleave pBR322 DNA under ultraviolet radiation. |
PubMed: | 8-MOP vs 5-MOP. |
PubMed: | A reappraisal of the use of 5-methoxypsoralen in the therapy of psoriasis. |
PubMed: | The evolution of photochemotherapy with psoralens and UVA (PUVA): 2000 BC to 1992 AD. |
PubMed: | The effect on liver transaminases of phototoxic drugs used in systemic photochemotherapy. |
PubMed: | Liquid formulations of 8-methoxypsoralen (8-MOP) and 5-MOP: a prospective double-blind crossover assessment of acute non-phototoxic adverse effects. |
PubMed: | Transformation and degradation of leukotriene B4, 12-hydroxyeicosatetraenoic acid and 5-hydroxyeicosatetraenoic acid induced by ultraviolet radiation. |
PubMed: | Is postmenopausal osteoporosis related to pineal gland functions? |
PubMed: | [Chemical constituents of Ledebouriella seseloides Wolff]. |
PubMed: | A new micronized 5-methoxypsoralen preparation. Higher bioavailability and lower UVA dose requirement. |
PubMed: | Quantitation of plasma levels of 8-methoxypsoralen by competitive enzyme-linked immunosorbent assay. |
PubMed: | Photoprotection and 5-MOP photochemoprotection from UVR-induced DNA damage in humans: the role of skin type. |
PubMed: | Metabolism of 5-methoxypsoralen by Saccharomyces cerevisiae. |
PubMed: | Study of the skin concentrations after administration of the various phototoxic drugs. |
PubMed: | 5-Methoxypsoralen enhances plasma melatonin concentrations in the male rat: non-noradrenergic-mediated stimulation and lack of effect in pinealectomized animals. |
PubMed: | Dietary intake and risk assessment of phototoxic furocoumarins in humans. |
PubMed: | Treatment of vitiligo with oral 5-methoxypsoralen. |
PubMed: | Dark interaction of 5-methoxypsoralen and 8-methoxypsoralen with erythrocyte ghosts: a fluorescence and circular dichroism study. |
PubMed: | Simple equilibrium dialysis-high-performance liquid chromatographic method for the in vitro assessment of 5-methoxypsoralen bound to human albumin. |
PubMed: | High-performance liquid chromatographic determination of citropten and bergapten in suction blister fluid after solar product application in humans. |
PubMed: | Phototoxicity due to Cachrys libanotis. |
PubMed: | Mechanism of action of psoralens: isobologram analysis reveals that ultraviolet light potentiation of psoralen action is not additive but synergistic. |
PubMed: | Peak blistering point: influence on fluid levels of 5-MOP in human skin in vivo after systemic administration. |
PubMed: | Citropten and bergapten suction blister fluid concentrations after solar product application in man. |
PubMed: | Use of a surface recovery technique to evaluate percutaneous absorption of 5-methoxypsoralen in humans. |
PubMed: | Analysis of 8-methoxypsoralen by high-performance liquid chromatography. |
PubMed: | Phototoxic properties of perfumes containing bergamot oil on human skin: photoprotective effect of UVA and UVB sunscreens. |
PubMed: | Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model. |
PubMed: | Genotoxicity of bergapten and bergamot oil in Saccharomyces cerevisiae. |
PubMed: | The relationship between ECT nonresponsiveness and calcification of the pineal gland in bipolar patients. |
PubMed: | Severe phototoxic burn following celery ingestion. |
PubMed: | Psoralens stimulate mouse melanocyte and melanoma tyrosinase activity in the absence of ultraviolet light. |
PubMed: | 5-Methoxypsoralen as a specific stimulating agent of melatonin secretion in humans. |
PubMed: | Repair of furocoumarin-plus-UVA-induced damage and mutagenic consequences in eukaryotic cells. |
PubMed: | To tan or not to tan. |
PubMed: | Effect on topical 5-methoxypsoralen on tumorigenesis induced in albino and pigmented hairless mouse skin by UV irradiation. |
PubMed: | Formation of cyclobutane thymine dimers photosensitized by pyridopsoralens: a triplet-triplet energy transfer mechanism. |
PubMed: | [Photo-onycholysis caused by 5-MOP (Psoraderm) and the application of the imputation method of drug effects]. |
PubMed: | 5-MOP induced protection against epidermal DNA damage by ultraviolet radiation in human skin. |
PubMed: | Chronopharmacokinetics of 5-methoxypsoralen. |
PubMed: | Heracleum mantegazzianum growth phases and furocoumarin content. |
PubMed: | Oxidative DNA damage photo-induced by 3-carbethoxypsoralen and other furocoumarins. Mechanisms of photo-oxidation and recognition by repair enzymes. |
PubMed: | To tan or not to tan. A burning question. |
PubMed: | [The effect of furanocoumarins on microsomal oxidation in the rat liver]. |
PubMed: | The effects of bergapten and sunlight on cutaneous pigmentation. |
PubMed: | Abnormal melatonin response to 5-methoxypsoralen in dementia. |
PubMed: | Geometry of intercalation of psoralens in DNA approached by molecular mechanics. |
PubMed: | Effects of active compounds isolated from Angelica shikokiana on lipid metabolism in fat cells. |
PubMed: | Antifertility principle of Ruta graveolens. |
PubMed: | Melanonychia induced by systemic photochemotherapy. |
PubMed: | 5-Methoxypsoralen increases evening sleepiness in humans: possible involvement of the melatonin secretion. |
PubMed: | 5-Methoxypsoralen increases the sensitivity of the retina to light in humans. |
PubMed: | Further evidence for photoinduced genotoxicity of dictamnine as shown by prophage induction. |
PubMed: | Relative affinity of 5-methoxypsoralen and 8-methoxypsoralen towards beta-cyclodextrin: a fluorescence, circular dichroism and chromatographic study. |
PubMed: | Induction and removal of DNA interstrand cross-links in V-79 Chinese hamster cells measured by hydroxylapatite chromatography after treatments with bifunctional furocoumarins. |
PubMed: | Biosynthesis of psoralens. Psoralen 5-monooxygenase activity from elicitor-treated Ammi majus cells. |
PubMed: | Photophysical behaviour of 5-methoxypsoralen in dioxane-water mixtures. |
PubMed: | Phototherapeutic, photobiologic, and photosensitizing properties of khellin. |
PubMed: | Sequence specificity in photoreaction of various psoralen derivatives with DNA: role in biological activity. |
PubMed: | 5-Methoxypsoralen (Bergapten) for photochemotherapy. Bioavailability, phototoxicity, and clinical efficacy in psoriasis of a new drug preparation. |
PubMed: | Evidence for uptake of 8-methoxypsoralen and 5-methoxypsoralen by cellular nuclei. |
PubMed: | Inhibition of UV radiation-induced DNA damage by a 5-methoxypsoralen tan in human skin. |
PubMed: | Antidepressant effect of 5-methoxypsoralen: a preliminary report. |
PubMed: | Biopharmaceutics, pharmacokinetics and pharmacology of psoralens. |
PubMed: | Modification of 5-methoxypsoralen phototumorigenesis by UVB sunscreens: a statistical and histologic study in the hairless albino mouse. |
PubMed: | 5-Methoxy psoralen, etretinate, and UVA for psoriasis. |
PubMed: | Kinetics of 8-methoxypsoralen and 5-methoxypsoralen distribution in guinea pig serum, epidermis and ocular lens. |
PubMed: | Estimation of an index of hydrophobicity of DNA interior using 5-methoxypsoralen as a fluorescent probe. |
PubMed: | 5-Methoxypsoralen increases the plasma melatonin levels in humans. |
PubMed: | Toxicity of 8-methoxypsoralen, 5-methoxypsoralen, 3-carbethoxypsoralen, or 5-methylisopsoralen with ultraviolet radiation in the hairless (HRA/Skh) mouse. |
PubMed: | The clastogenic effect of 5-methoxypsoralen plus UV-A in human lymphocytes in vitro and its modification by the anticlastogen beta-aminoethylisothiouronium. |
PubMed: | Inactivation of human liver cytochrome P-450 by the drug methoxsalen and other psoralen derivatives. |
PubMed: | Chromosome damage induced in human lymphocytes by 5-methoxypsoralen and 8-methoxypsoralen plus UV-A. |
PubMed: | Psoralens potentiate ultraviolet light-induced inhibition of epidermal growth factor binding. |
PubMed: | Dark interaction and oxygen dependent photobinding between an aromatic tetrapeptide and DNA modified by 5-methoxypsoralen monoadducts. |
PubMed: | Ocular effects of treatment with various psoralen derivatives and ultraviolet-A (UVA) radiation in HRA/Skh hairless mice. |
PubMed: | Cutaneous phototoxicity reactions. |
PubMed: | Inactivation and induction of cytochrome P-450 by various psoralen derivatives in rats. |
PubMed: | [Problems posed by the therapeutic use of photosensitizers in dermatology]. |
PubMed: | Detection of furocoumarins in plants and plant products with an ultrasensitive biological photoassay employing a DNA-repair-deficient bacterium. |
PubMed: | Genotoxic activity of some water-soluble derivatives of 5-methoxypsoralen and 8-methoxypsoralen. |
PubMed: | [Testing the monooxygenase enzyme system of the liver using the antipyrine test in psoriasis patients]. |
PubMed: | Genetic effects of DNA mono- and diadducts photoinduced by furocoumarins in eukaryotic cells. |
PubMed: | Clinical pharmacokinetics of methoxsalen and other psoralens. |
PubMed: | 5-Methoxypsoralen. |
PubMed: | Induction of DNA-DNA cross-link formation in human cells by various psoralen derivatives. |
PubMed: | Genotoxic effects and DNA photoadducts induced in Chinese hamster V79 cells by 5-methoxypsoralen and 8-methoxypsoralen. |
PubMed: | Relationship between lesions photoinduced by mono- and bi-functional furocoumarins in DNA and genotoxic effects in diploid yeast. |
PubMed: | Photobiological properties of some water-soluble 5-MOP and 8-MOP derivatives. |
PubMed: | The bergapten content of garden parsley and its significance in causing cutaneous photosensitization. |
PubMed: | [Furocoumarins in essential oils. Identification and determination of 5-methoxypsoralen in sun products]. |
PubMed: | Mechanism of photosensitivity reactions to diseased celery. |
PubMed: | Comparison of bioavailability and phototoxicity of two oral preparations of 5-methoxypsoralen. |
PubMed: | The Candida phototoxicity test. The sensitivity of different strains and species of Candida, standardization attempts and analysis of the dose-response curves for 5- and 8-methoxypsoralen. |
PubMed: | [Determination of 5-methoxypsoralen in suntan cosmetics]. |
PubMed: | Photochemotherapy using pyridopsoralens. |
PubMed: | Chemical structure of psoralen-nucleic acid photoadducts. |
PubMed: | A study of the phototoxicity of lemon oil. |
PubMed: | Difference in topical and systemic reactivity of psoralens: determinations of epidermal and serum levels. |
PubMed: | Psoralen and ultraviolet A effects on epidermal ornithine decarboxylase induction and DNA synthesis in the hairless mouse. |
PubMed: | Pharmacokinetics and pharmacodynamics of psoralens after oral administration: considerations and conclusions. |
PubMed: | In vitro characterization of the reaction of four psoralen derivatives with DNA. |
PubMed: | Safety and therapeutic effectiveness of selected psoralens in psoriasis. |
PubMed: | Induction of sister chromatid exchanges and gene mutations in Chinese hamster ovary cells by psoralens. |
PubMed: | Chemical characterization of psoralens used in the National Toxicology Program research projects. |
PubMed: | Synthesis of some bergapten and ammajin derivatives with potential antibacterial activity. |
PubMed: | Quantitative assessment of UV-induced changes in microcirculatory flow by laser Doppler velocimetry. |
PubMed: | [Coumarin derivatives as protective agents against the cytotoxic and mutagenic effect of 5-methoxypsoralen and UV-A in Chlamydomonas reinhardii]. |
PubMed: | Ficus carica; isolation and quantification of the photoactive components. |
PubMed: | Binding of 5-methoxypsoralen to human serum low density lipoproteins. |
PubMed: | Frameshift mutagenicity in Salmonella typhimurium of furocoumarins in the dark. |
PubMed: | Production of active oxygen species (1O2 and O2-.) by psoralens and ultraviolet radiation (320-400 nm). |
PubMed: | Is psoralen-containing sunscreen tumorigenic in hairless mice? |
PubMed: | [Loss of vitality of polymorphonuclear neutrophilic granulocytes due to 5- or 8-methoxypsoralen and UV radiation]. |
PubMed: | The induction of prophage expression in different Salmonella typhimurium strains by DNA cross-linking and monoadduct forming psoralens and longwave ultraviolet radiation. |
PubMed: | Inhibition of bergaptene toxicity by UV-A filters. |
PubMed: | Phototoxicity from furocoumarins (psoralens) of Heracleum laciniatum in a patient with vitiligo. Action spectrum studies on bergapten, pimpinellin, angelicin and sphondin. |
PubMed: | Photochemical reactions of Heracleum laciniatum. Influence of dimethyl sulphoxide and corticosteroids. |
PubMed: | Furocoumarins of Heracleum laciniatum: isolation, phototoxicity, absorption and action spectra studies. |
PubMed: | Psoralen-containing sunscreen is tumorigenic in hairless mice. |
PubMed: | Some photophysical properties of 3-carbethoxypsoralen, 8-methoxypsoralen and 5-methoxypsoralen triplet states. |
PubMed: | A comparison of the phototumorigenic potential of 8-MOP and 5-MOP in hairless albino mice exposed to solar simulated radiation. |
PubMed: | The furocoumarin composition of Pituranthos triradiatus. |
PubMed: | Photobiological activity of 5,7-dimethoxycoumarin. |
PubMed: | [Effect of 5-methoxypsoralen on the phytohemagglutinin-stimulated lymphocyte transformation rate in vitro]. |
PubMed: | [Quantitative determination of 5-methoxypsoralen in plasma by liquid chromatography and spectrofluorometric detection]. |
PubMed: | [Lethal lymphocyte damage caused by angular psoralen derivatives]. |
PubMed: | The sunburn cell in hairless mouse epidermis: quantitative studies with UV-A radiation and mono- and bifunctional psoralens. |
PubMed: | Sunscreens: topical and systemic approaches for protection of human skin against harmful effects of solar radiation. |
PubMed: | Psoralen phototoxicity: correlation with serum and epidermal 8-methoxypsoralen and 5-methoxypsoralen in the guinea pig. |
PubMed: | [Determination of the coumarinic constituents of Ficus carica leaves by HPLC]. |
PubMed: | Comparative photobiology of psoralens. |
PubMed: | Psoralen-containing sunscreen induces phototoxicity and epidermal ornithine decarboxylase activity. |
PubMed: | Genotoxicity of 5-methoxypsoralen and near ultraviolet light in repair-deficient strains of Escherichia coli WP2. |
PubMed: | [5-Methoxypsoralen: bioavailability and pharmacokinetics]. |
PubMed: | Comparative studies on the photosensitizing potency of 5-methoxypsoralen and 8-methoxypsoralen as measured by cytolysis in Paramecium caudatum and Tetrahymena pyriformis, and growth inhibition and survival in Candida albicans. |
PubMed: | Sunscreens and their side effects. |
PubMed: | Chromosomal damage induced by furocoumarins and UVA in hamster and human cells including cells from patients with ataxia telangiectasia and xeroderma pigmentosum. |
PubMed: | Inappropriate regulations governing the use of oil of bergamot in suntan preparations. |
PubMed: | Serum and urine concentrations of 5-methoxypsoralen after oral administration. |
PubMed: | Sunscreens and their side effects. |
PubMed: | Analysis of methoxsalen in plasma by reversed-phase high-performance liquid chromatography. |
PubMed: | [Comparison of photomutagenic activities of 5-mop (bergapten) and 8-mop (xanthotoxin) in chlamydomonas reinhardii (author's transl)]. |
PubMed: | Photochemotherapy of skin-diseases: comparative studies on the photochemical and photobiological properties of various mono- and bifunctional agents. |
PubMed: | Mutagenic activity of three monofunctional and three bifunctional furocoumarins in yeast (Saccharomyces cerevisiae). |
PubMed: | [Photosensitization effect of 5- or 8-methoxypsoralen on human cultured lymphocytes]. |
PubMed: | Berloque dermatitis - a continuing cosmetic problem. |
PubMed: | Determination of bergapten in suntan cosmetics. |
PubMed: | A comparison of the photochemical actions of 5- and 8-methoxypsoralen on CHO cells. |
PubMed: | 5-Methoxypsoralen, the melanogenic additive in sun-tan preparations, is tumorigenic in mice exposed to 365 nm u.v. radiation. |
PubMed: | Clinical aspects of photochemotherapy. |
PubMed: | Determination of 8-methoxypsoralen in suction-blister fluid and serum by liquid chromatography. |
PubMed: | A pulse radiolysis study of the complexing of furocoumarins with DNA and proteins. |
PubMed: | Possible cancer hazard associated with 5-methoxypsoralen in suntan preparation. |
PubMed: | 5-Methoxypsoralen, an ingredient in several suntan preparations, has lethal, mutagenic and clastogenic properties. |
PubMed: | Determination of nanogram levels of the anticoagulant acenocoumarin in serum by high-performance liquid chromatography. |
PubMed: | Possible cancer hazard associated with 5-methoxypsoralen in suntan preparation. |
PubMed: | Possible cancer hazard associated with 5-methoxypsoralen in suntan preparation. |
PubMed: | Possible cancer hazard associated with 5-methoxypsoralen in suntan preparation. |
PubMed: | A rapid method for measuring drug enrichment in epidermis. |
PubMed: | Reversible binding of 5- and 8-methoxypsoralen to human serum proteins (albumin) and to epidermis in vitro. |
PubMed: | Possible cancer hazard associated with 5-methoxypsoralen in suntan preparations. |
PubMed: | 5-Methoxypsoralen (Bergapten) in photochemotherapy of psoriasis. |
PubMed: | Drug-protein interaction: plasma protein binding of furocoumarins. |
PubMed: | Phototoxicity of Dictamnus alba. |
PubMed: | A study of oil of bergamot and its importance as a phototoxic agent. II. Factors which affect the phototoxic reaction induced by bergamot oil and psoralen derivatives. |
PubMed: | Photochemotherapy (PUVA) and psoriasis: comparison of 8-MOP and 8-MOP/5-MOP. |
PubMed: | Determination of bergapten in fragrance preparations by thin layer chromatography and spectrophotofluorometry. |
PubMed: | Isolation and identification of xanthotoxin (8-methoxypsoralen) and bergapten (5-methoxypsoralen) from celery infected with Sclerotinia sclerotiorum. |
PubMed: | [Photodermatosis due to bergaptene (considerations apropos of an epidemic in workers occupied in the celery harvest)]. |
PubMed: | [Research on the bergaptene content of celery and parsley]. |
PubMed: | [Research on the content of psoralen and bergaptene in the leaves of Ficus carica]. |