benzyl isothiocyanate, 622-78-6

Articles:

Info:	miscellaneous nitrogen derivatives
PubMed:	Benzyl isothiocyanate inhibits IL-13 expression in human basophilic KU812 cells.
J-Stage:	a-Tocopherol Sensitizes Human Leukemia HL-60 Cells to Apoptosis Induced by Benzyl Isothiocyanate
PubMed:	Chemo-predictive assay for targeting cancer stem-like cells in patients affected by brain tumors.
PubMed:	Purification of Active Myrosinase from Plants by Aqueous Two-Phase Counter-Current Chromatography.
PubMed:	Glycyl endopeptidase from papaya latex: partial purification and use for production of fish gelatin hydrolysate.
PubMed:	Efficient 1-Step Radiolabeling of Monoclonal Antibodies to High Specific Activity with 225Ac for α-Particle Radioimmunotherapy of Cancer.
PubMed:	Stable, water extractable isothiocyanates from Moringa oleifera leaves attenuate inflammation in vitro.
PubMed:	Benzyl isothiocyanate suppresses high-fat diet-stimulated mammary tumor progression via the alteration of tumor microenvironments in obesity-resistant BALB/c mice.
PubMed:	Antiinflammatory activity of glucomoringin isothiocyanate in a mouse model of experimental autoimmune encephalomyelitis.
PubMed:	Review: an exposition of medicinal preponderance of Moringa oleifera (Lank.).
PubMed:	Cytotoxic effect of Reseda lutea L.: A case of forgotten remedy.
PubMed:	In vitro and in vivo studies of trypanocidal activity of dietary isothiocyanates.
PubMed:	Benzyl isothiocyanate inhibits HNSCC cell migration and invasion, and sensitizes HNSCC cells to cisplatin.
PubMed:	Antitrypanosomal isothiocyanate and thiocarbamate glycosides from Moringa peregrina.
PubMed:	A chemical approach for the reduction of beauvericin in a solution model and in food systems.
PubMed:	Antibacterial activity of glucomoringin bioactivated with myrosinase against two important pathogens affecting the health of long-term patients in hospitals.
PubMed:	Odour-active compounds in papaya fruit cv. Red Maradol.
PubMed:	Insights into the mode of action of benzyl isothiocyanate on Campylobacter jejuni.
PubMed:	Oral administration of benzyl-isothiocyanate inhibits in vivo growth of subcutaneous xenograft tumors of human malignant melanoma A375.S2 cells.
PubMed:	Determination of benzyl isothiocyanate metabolites in human plasma and urine by LC-ESI-MS/MS after ingestion of nasturtium (Tropaeolum majus L.).
PubMed:	Benzyl isothiocyanate: double trouble for breast cancer cells.
PubMed:	Isothiocyanates protect against oxidized LDL-induced endothelial dysfunction by upregulating Nrf2-dependent antioxidation and suppressing NFκB activation.
PubMed:	Inhibitory effect of benzyl isothiocyanate on proliferation in vitro of human glioma cells.
PubMed:	Dietary chemopreventative benzyl isothiocyanate inhibits breast cancer stem cells in vitro and in vivo.
PubMed:	High-performance liquid chromatographic enantioseparation of (RS)-bupropion using isothiocyanate-based chiral derivatizing reagents.
PubMed:	Downregulation of Mcl-1 through inhibition of translation contributes to benzyl isothiocyanate-induced cell cycle arrest and apoptosis in human leukemia cells.
PubMed:	Antimicrobial isothiocyanates from the seeds of Moringa oleifera Lam.
PubMed:	Suppression of FOXQ1 in benzyl isothiocyanate-mediated inhibition of epithelial-mesenchymal transition in human breast cancer cells.
PubMed:	Study of the chemical reduction of the fumonisins toxicity using allyl, benzyl and phenyl isothiocyanate in model solution and in food products.
PubMed:	Stability of benzylic-type isothiocyanates in hydrodistillation-mimicking conditions.
PubMed:	Benzyl isothiocyanate induces protective autophagy in human prostate cancer cells via inhibition of mTOR signaling.
PubMed:	Apoptosis induced by benzyl isothiocyanate in gefitinib-resistant lung cancer cells is associated with Akt/MAPK pathways and generation of reactive oxygen species.
PubMed:	Erucin and benzyl isothiocyanate suppress growth of late stage primary human ovarian carcinoma cells and telomerase activity in vitro.
PubMed:	Isothiocyanates ameliorate the symptom of heart dysfunction and mortality in a murine AIDS model by inhibiting apoptosis in the left ventricle.
PubMed:	Antimicrobial activities of isothiocyanates against Campylobacter jejuni isolates.
PubMed:	Development and application of a method for identification of isothiocyanate-targeted molecules in colon cancer cells.
PubMed:	Benzyl isothiocyanate disturbs lipid metabolism in rats in a way independent of its thyroid impact following in vivo long-term treatment and in vitro adipocytes studies.
PubMed:	Identifying and characterizing binding sites on the irreversible inhibition of human glutathione S-transferase P1-1 by S-thiocarbamoylation.
PubMed:	Proteomic analysis of covalent modifications of tubulins by isothiocyanates.
PubMed:	Enhancement of cisplatin cytotoxicity by benzyl isothiocyanate in HL-60 cells.
PubMed:	Notch2 activation by benzyl isothiocyanate impedes its inhibitory effect on breast cancer cell migration.
PubMed:	Benzyl isothiocyanate causes FoxO1-mediated autophagic death in human breast cancer cells.
PubMed:	Critical role of p53 upregulated modulator of apoptosis in benzyl isothiocyanate-induced apoptotic cell death.
PubMed:	α-Tocopherol sensitizes human leukemia HL-60 cells to apoptosis induced by benzyl isothiocyanate.
PubMed:	Content determination of benzyl glucosinolate and anti-cancer activity of its hydrolysis product in Carica papaya L.
PubMed:	Cytotoxicity of benzyl isothiocyanate in normal renal proximal tubular cells and its modulation by glutathione.
PubMed:	Hepatoma-derived growth factor regulates breast cancer cell invasion by modulating epithelial--mesenchymal transition.
PubMed:	Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.
PubMed:	Contact and fumigant toxicity of Armoracia rusticana essential oil, allyl isothiocyanate and related compounds to Dermatophagoides farinae.
PubMed:	Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-α/VEGF/Rho-GTPases: pivotal role of STAT-3.
PubMed:	Nanoemulsions of cancer chemopreventive agent benzyl isothiocyanate display enhanced solubility, dissolution, and permeability.
PubMed:	Benzyl isothiocyanate inhibits basal and hepatocyte growth factor-stimulated migration of breast cancer cells.
PubMed:	Validated high-performance liquid chromatographic enantioseparation of selenomethionine using isothiocyanate based chiral derivatizing reagents.
PubMed:	Varied response of Spodoptera littoralis against Arabidopsis thaliana with metabolically engineered glucosinolate profiles.
PubMed:	Benzyl isothiocyanate sensitizes human pancreatic cancer cells to radiation by inducing apoptosis.
PubMed:	Benzyl isothiocyanate, a major component from the roots of Salvadora persica is highly active against Gram-negative bacteria.
PubMed:	Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα.
PubMed:	Engineering GST M2-2 for high activity with indene 1,2-oxide and indication of an H-site residue sustaining catalytic promiscuity.
PubMed:	MicroRNA-375 and MicroRNA-221: Potential Noncoding RNAs Associated with Antiproliferative Activity of Benzyl Isothiocyanate in Pancreatic Cancer.
PubMed:	Inhibition of lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression by 4-[(2'-O-acetyl-α-L-rhamnosyloxy)benzyl]isothiocyanate from Moringa oleifera.
PubMed:	Mitogen-activated protein kinase mediates the apoptosis of highly metastatic human non-small cell lung cancer cells induced by isothiocyanates.
PubMed:	Synthesis and antiproliferative activity of novel α- and β-dialkoxyphosphoryl isothiocyanates.
PubMed:	Phenethyl isothiocyanate sensitizes human cervical cancer cells to apoptosis induced by cisplatin.
PubMed:	Characteristics of papaya seed oils obtained by extrusion-expelling processes.
PubMed:	Evaluation of antibacterial activity of 3-butenyl, 4-pentenyl, 2-phenylethyl, and benzyl isothiocyanate in Brassica vegetables.
PubMed:	Benzyl isothiocyanate inhibits epithelial-mesenchymal transition in cultured and xenografted human breast cancer cells.
PubMed:	Assessment of the protective effects of selected dietary anticarcinogens against DNA damage and cytogenetic effects induced by benzo[a]pyrene in C57BL/6J mice.
PubMed:	Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.
PubMed:	Pancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway.
PubMed:	Stimulation of phagocytosis by sulforaphane.
PubMed:	The roles of AIF and Endo G in the apoptotic effects of benzyl isothiocyanate on DU 145 human prostate cancer cells via the mitochondrial signaling pathway.
PubMed:	Oral administration of benzyl-isothiocyanate inhibits solid tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice.
PubMed:	Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3.
PubMed:	Effectiveness of different solid-phase microextraction fibres for differentiation of selected Madeira island fruits based on their volatile metabolite profile--identification of novel compounds.
PubMed:	Isothiocyanates inhibit proteasome activity and proliferation of multiple myeloma cells.
PubMed:	Characterization and antimicrobial activity of 4-(β-D-glucopyranosyl-1→4-α-L-rhamnopyranosyloxy)-benzyl thiocarboxamide; a novel bioactive compound from Moringa oleifera seed extract.
PubMed:	The toxic effects of benzyl glucosinolate and its hydrolysis product, the biofumigant benzyl isothiocyanate, to Folsomia fimetaria.
PubMed:	Sensitization of non-small cell lung cancer cells to cisplatin by naturally occurring isothiocyanates.
PubMed:	Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruits.
PubMed:	BITC Sensitizes Pancreatic Adenocarcinomas to TRAIL-induced Apoptosis.
PubMed:	Candidate dietary phytochemicals modulate expression of phase II enzymes GSTP1 and NQO1 in human lung cells.
PubMed:	Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells.
PubMed:	Benzyl isothiocyanate (BITC) inhibits migration and invasion of human gastric cancer AGS cells via suppressing ERK signal pathways.
PubMed:	p53-Independent apoptosis by benzyl isothiocyanate in human breast cancer cells is mediated by suppression of XIAP expression.
PubMed:	Benzyl isothiocyanate-mediated inhibition of histone deacetylase leads to NF-kappaB turnoff in human pancreatic carcinoma cells.
PubMed:	Preclinical evaluation of monoclonal antibody 14C5 for targeting pancreatic cancer.
PubMed:	Inhibition of human breast cancer xenograft growth by cruciferous vegetable constituent benzyl isothiocyanate.
PubMed:	Trypanocidal and antileukaemic effects of the essential oils of Hagenia abyssinica, Leonotis ocymifolia, Moringa stenopetala, and their main individual constituents.
PubMed:	Immunochemical detection of food-derived isothiocyanate as a lysine conjugate.
PubMed:	Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway.
PubMed:	New biomarkers for monitoring the levels of isothiocyanates in humans.
PubMed:	[Antimicrobial efficacy of benzyl isothiocyanate].
PubMed:	Inhibition of apoptosis in human retinal pigment epithelial cells treated with benzo(e)pyrene, a toxic component of cigarette smoke.
PubMed:	Prevention of mammary carcinogenesis in MMTV-neu mice by cruciferous vegetable constituent benzyl isothiocyanate.
PubMed:	Growth-inhibiting activities of phenethyl isothiocyanate and its derivatives against intestinal bacteria.
PubMed:	Benzyl isothiocyanate exhibits anti-inflammatory effects in murine macrophages and in mouse skin.
PubMed:	Differing mechanisms of simple nitrile formation on glucosinolate degradation in Lepidium sativum and Nasturtium officinale seeds.
PubMed:	A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor.
PubMed:	Dietary agent, benzyl isothiocyanate inhibits signal transducer and activator of transcription 3 phosphorylation and collaborates with sulforaphane in the growth suppression of PANC-1 cancer cells.
PubMed:	Aggresome-like structure induced by isothiocyanates is novel proteasome-dependent degradation machinery.
PubMed:	Anti-proliferative and proapoptotic effects of benzyl isothiocyanate on human pancreatic cancer cells is linked to death receptor activation and RasGAP/Rac1 down-modulation.
PubMed:	Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells.
PubMed:	Re: The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate.
PubMed:	Benzyl isothiocyanate sensitizes human pancreatic cancer cells to radiation therapy.
PubMed:	Diverse chemicals including aryl hydrocarbon receptor ligands modulate transcriptional activity of the 3'immunoglobulin heavy chain regulatory region.
PubMed:	Phytochemical induction of cell cycle arrest by glutathione oxidation and reversal by N-acetylcysteine in human colon carcinoma cells.
PubMed:	Cancer preventive isothiocyanates induce selective degradation of cellular alpha- and beta-tubulins by proteasomes.
PubMed:	The antimicrobial effects of glucosinolates and their respective enzymatic hydrolysis products on bacteria isolated from the human intestinal tract.
PubMed:	Benzyl isothiocyanate inhibits murine WEHI-3 leukemia cells in vitro and promotes phagocytosis in BALB/c mice in vivo.
PubMed:	Degradation and sorption of 2-propenyl and benzyl isothiocyanate in soil.
PubMed:	Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L.
PubMed:	The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate.
PubMed:	Isothiocyanates repress estrogen receptor alpha expression in breast cancer cells.
PubMed:	Binding to protein by isothiocyanates: a potential mechanism for apoptosis induction in human non small lung cancer cells.
PubMed:	(-)-Epigallocatechin-3-gallate potentiates the cytotoxicity induced by benzyl isothiocyanate and hydrogen peroxide in human Jurkat T lymphocytes.
PubMed:	Acaricidal constituents isolated from Sinapis alba L. seeds and structure-activity relationships.
PubMed:	Benzylglucosinolate, benzylisothiocyanate, and myrosinase activity in papaya fruit during development and ripening.
PubMed:	Dietary isothiocyanate mediated apoptosis of human cancer cells is associated with Bcl-xL phosphorylation.
PubMed:	Benzyl isothiocyanate targets mitochondrial respiratory chain to trigger reactive oxygen species-dependent apoptosis in human breast cancer cells.
PubMed:	ATP depletion alters the mode of cell death induced by benzyl isothiocyanate.
PubMed:	Benzyl isothiocyanate inhibits metalloproteinase-2/-9 expression by suppressing the mitogen-activated protein kinase in SK-Hep1 human hepatoma cells.
PubMed:	Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents.
PubMed:	Modifying effects of dietary factors on (-)-epigallocatechin-3-gallate-induced pro-matrix metalloproteinase-7 production in HT-29 human colorectal cancer cells.
PubMed:	Formation and degradation kinetics of the biofumigant benzyl isothiocyanate in soil.
PubMed:	Comments regarding: Benzyl isothiocyanate (BITC) induces apoptosis in ovarian cancer cells in vitro Kalkunte S, Swamy N, Dizon DS, Brard L. J Exp Ther Oncol.5(4):287-300, 2006.
PubMed:	Papaya seed represents a rich source of biologically active isothiocyanate.
PubMed:	Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak.
PubMed:	Selective cytotoxicity of benzyl isothiocyanate in the proliferating fibroblastoid cells.
PubMed:	Benzyl isothiocyanate-induced DNA damage causes G2/M cell cycle arrest and apoptosis in human pancreatic cancer cells.
PubMed:	p38MAPK mediates benzyl isothiocyanate-induced p21WAF1 expression in vascular smooth muscle cells via the regulation of Sp1.
PubMed:	Benzyl isothiocyanate (BITC) induces apoptosis in ovarian cancer cells in vitro.
PubMed:	Cell death induction by isothiocyanates and their underlying molecular mechanisms.
PubMed:	Haplotype-environment interactions that regulate the human glutathione S-transferase P1 promoter.
PubMed:	Newly constructed stable reporter cell lines for mechanistic studies on electrophile-responsive element-mediated gene expression reveal a role for flavonoid planarity.
PubMed:	Molecular cloning of AbGst1 encoding a glutathione transferase differentially expressed during exposure of Alternaria brassicicola to isothiocyanates.
PubMed:	Raphanus sativus and its isothiocyanates inhibit vascular smooth muscle cells proliferation and induce G(1) cell cycle arrest.
PubMed:	Characterization of two Arabidopsis thaliana glutathione S-transferases.
PubMed:	The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in human bladder cancer cells.
PubMed:	Effect of isothiocyanates on nuclear accumulation of NF-kappaB, Nrf2, and thioredoxin in caco-2 cells.
PubMed:	Protective effects of benzyl isothiocyanate and sulforaphane but not resveratrol against initiation of pancreatic carcinogenesis in hamsters.
PubMed:	Dietary isothiocyanates modify mitochondrial functions through their electrophilic reaction.
PubMed:	Effects of benzyl and phenethyl isothiocyanate on P450s 2A6 and 2A13: potential for chemoprevention in smokers.
PubMed:	(89)Zr as a PET surrogate radioisotope for scouting biodistribution of the therapeutic radiometals (90)Y and (177)Lu in tumor-bearing nude mice after coupling to the internalizing antibody cetuximab.
PubMed:	Modulation of jejunal contractions by extract of Carica papaya L. seeds.
PubMed:	The role of c-Jun in the AP-1 activation induced by naturally occurring isothiocyanates.
PubMed:	The identification of 1,3-oxazolidine-2-thiones and 1,3-thiazolidine-2-thiones from the reaction of glucose with benzyl isothiocyanate.
PubMed:	Benzyl isothiocyanate inhibits oxidative stress in mouse skin: Involvement of attenuation of leukocyte infiltration.
PubMed:	Benzyl isothiocyanate modifies expression of the G2/M arrest-related genes.
PubMed:	A novel function of benzyl isothiocyanate in vascular smooth muscle cells: the role of ERK1/2, cell cycle regulation, and matrix metalloproteinase-9.
PubMed:	Dietary isothiocyanates inhibit Caco-2 cell proliferation and induce G2/M phase cell cycle arrest, DNA damage, and G2/M checkpoint activation.
PubMed:	Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities.
PubMed:	Induction of apoptosis in a non-small cell human lung cancer cell line by isothiocyanates is associated with P53 and P21.
PubMed:	Glutathione S-transferase Pi has at least three distinguishable xenobiotic substrate sites close to its glutathione-binding site.
PubMed:	Dietary organic isothiocyanates are cytotoxic in human breast cancer MCF-7 and mammary epithelial MCF-12A cell lines.
PubMed:	Do aberrant crypt foci have predictive value for the occurrence of colorectal tumours? Potential of gene expression profiling in tumours.
PubMed:	Cysteine/cystine couple is a newly recognized node in the circuitry for biologic redox signaling and control.
PubMed:	Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells.
PubMed:	Pregnancy outcomes following pre- and post-implantation exposure of Sprague-Dawley rats to benzyl isothiocyanate.
PubMed:	A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation.
PubMed:	Effect of benzyl isothiocyanate on spontaneous and induced force of rat uterine contraction.
PubMed:	In vitro digestion of sinigrin and glucotropaeolin by single strains of Bifidobacterium and identification of the digestive products.
PubMed:	Benzyl isothiocyanate inhibits excessive superoxide generation in inflammatory leukocytes: implication for prevention against inflammation-related carcinogenesis.
PubMed:	Tocolytic and toxic activity of papaya seed extract on isolated rat uterus.
PubMed:	Enhancement of urinary bladder carcinogenesis by combined treatment with benzyl isothiocyanate and N-butyl-N-(4-hydroxybutyl)nitrosamine in rats after initiation.
PubMed:	Influence of plant and bacterial myrosinase activity on the metabolic fate of glucosinolates in gnotobiotic rats.
PubMed:	Requirement of a carbon spacer in benzyl isothiocyanate-mediated cytotoxicity and MAPK activation in head and neck squamous cell carcinoma.
PubMed:	Involvement of toxicity as an early event in urinary bladder carcinogenesis induced by phenethyl isothiocyanate, benzyl isothiocyanate, and analogues in F344 rats.
PubMed:	Enhancement of glutathione and g-glutamylcysteine synthetase, the rate limiting enzyme of glutathione synthesis, by chemoprotective plant-derived food and beverage components in the human hepatoma cell line HepG2.
PubMed:	Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide- and interferon-gamma-induced IkappaB degradation in RAW264.7 macrophages.
PubMed:	Effects of benzyl isothiocyanate and 2-phenethyl isothiocyanate on benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism in F-344 rats.
PubMed:	Effects of garden and water cress juices and their constituents, benzyl and phenethyl isothiocyanates, towards benzo(a)pyrene-induced DNA damage: a model study with the single cell gel electrophoresis/Hep G2 assay.
PubMed:	Effect of organic isothiocyanates on the P-glycoprotein- and MRP1-mediated transport of daunomycin and vinblastine.
PubMed:	Simultaneous treatment with benzyl isothiocyanate, a strong bladder promoter, inhibits rat urinary bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine.
PubMed:	Benzyl isothiocyanate: an effective inhibitor of polycyclic aromatic hydrocarbon tumorigenesis in A/J mouse lung.
PubMed:	Effects of benzyl isothiocyanate and phenethyl isothiocyanate on DNA adduct formation by a mixture of benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung.
PubMed:	Effects of papaya seed extract and benzyl isothiocyanate on vascular contraction.
PubMed:	Effect of naturally occurring organosulfur compounds on nitric oxide production in lipopolysaccharide-activated macrophages.
PubMed:	Palladium(0)-catalyzed enantioselective O,S-rearrangement of racemic O-allylic thiocarbamates: a new entry to enantioenriched allylic sulfur compounds.
PubMed:	Toxic effects of benzyl and allyl isothiocyanates and benzyl-isoform specific metabolites in the urinary bladder after a single intravesical application to rats.
PubMed:	Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis.
PubMed:	Involvement of the mitochondrial death pathway in chemopreventive benzyl isothiocyanate-induced apoptosis.
PubMed:	4-(Methylthio)-3-butenyl isothiocyanate, a principal antimutagen in daikon (Raphanus sativus; Japanese white radish).
PubMed:	Decomposition rates of isothiocyanate conjugates determine their activity as inhibitors of cytochrome p450 enzymes.
PubMed:	Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines.
PubMed:	Differential effects of naturally occurring isothiocyanates on the activities of cytochrome P450 2E1 and the mutant P450 2E1 T303A.
PubMed:	Benzyl isothiocyanate is the chief or sole anthelmintic in papaya seed extracts.
PubMed:	Successful and not so successful chemoprevention of tobacco smoke-induced lung tumors.
PubMed:	Effects of phenethyl isothiocyanate and benzyl isothiocyanate, individually and in combination, on lung tumorigenesis induced in A/J mice by benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
PubMed:	Inactivation of cytochrome P450 2B1 by benzyl isothiocyanate, a chemopreventative agent from cruciferous vegetables.
PubMed:	Effects of benzyl isothiocyanate on rat and human cytochromes P450: identification of metabolites formed by P450 2B1.
PubMed:	Effects of benzyl isothiocyanate and phenethyl isothiocyanate on benzo[a]pyrene metabolism and DNA adduct formation in the A/J mouse.
PubMed:	A glutathione S-transferase inducer from papaya: rapid screening, identification and structure-activity relationship of isothiocyanates.
PubMed:	Chemoprevention of tobacco-smoke lung carcinogenesis in mice after cessation of smoke exposure.
PubMed:	Mechanism of oxidative DNA damage induced by carcinogenic allyl isothiocyanate.
PubMed:	Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the glutathione S-transferase A5 and P1 subunits, and NAD(P)H:quinone oxidoreductase in rat liver.
PubMed:	Redox regulation of glutathione S-transferase induction by benzyl isothiocyanate: correlation of enzyme induction with the formation of reactive oxygen intermediates.
PubMed:	Glutathione redox potential in response to differentiation and enzyme inducers.
PubMed:	Isothiocyanates and freeze-dried strawberries as inhibitors of esophageal cancer.
PubMed:	Genotoxic effects of benzyl isothiocyanate, a natural chemopreventive agent.
PubMed:	Dietary compounds that induce cancer preventive phase 2 enzymes activate apoptosis at comparable doses in HT29 colon carcinoma cells.
PubMed:	Inactivation of cytochrome P450 2E1 by benzyl isothiocyanate.
PubMed:	Antimicrobial components of some cruciferae plants (Diplotaxis harra Forsk. and Erucaria microcarpa Boiss.)
PubMed:	An antitumor promoter from Moringa oleifera Lam.
PubMed:	Temporal effects of the detoxification enzyme inducer, benzyl isothiocyanate: activation of c-Jun N-terminal kinase prior to the transcription factors AP-1 and NFkappaB.
PubMed:	Chemoprevention of cancer by isothiocyanates, modifiers of carcinogen metabolism.
PubMed:	Modulation by phytochemicals of cytochrome P450-linked enzyme activity.
PubMed:	Inhibition of N'-nitrosonornicotine-induced esophageal tumorigenesis by 3-phenylpropyl isothiocyanate.
PubMed:	Reactions of a glucosinolate breakdown product (benzyl isothiocyanate) with myoglobin.
PubMed:	Strong promoting activity of phenylethyl isothiocyanate and benzyl isothiocyanate on urinary bladder carcinogenesis in F344 male rats.
PubMed:	Regulation of rat glutathione S-transferase A5 by cancer chemopreventive agents: mechanisms of inducible resistance to aflatoxin B1.
PubMed:	The environment of 5S rRNA in the ribosome: cross-links to the GTPase-associated area of 23S rRNA.
PubMed:	Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity.
PubMed:	Radioimmunotherapy for breast cancer using indium-111/yttrium-90 BrE-3: results of a phase I clinical trial.
PubMed:	Approaches to chemoprevention of lung cancer based on carcinogens in tobacco smoke.
PubMed:	Effects of isothiocyanates on cytochrome P-450 1A1 and 1A2 activity and on the mutagenicity of heterocyclic amines.
PubMed:	Enzyme induction and comparative oxidative desulfuration of isothiocyanates to isocyanates.
PubMed:	Inhibition of N-nitrosodimethylamine demethylase in rat and human liver microsomes by isothiocyanates and their glutathione, L-cysteine, and N-acetyl-L-cysteine conjugates.
PubMed:	Lack of inhibitory effect of benzyl isothiocyanate on 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in rats.
PubMed:	Influence of benzylisothiocyanate and 13-cis-retinoic acid on micronucleus formation induced by benzo[a]pyrene.
PubMed:	Aberrant crypts as a biomarker for colon cancer: evaluation of potential chemopreventive agents in the rat.
PubMed:	Chemoprevention of lung cancer by isothiocyanates.
PubMed:	In vitro and in vivo antitumor activity of benzyl isothiocyanate: a natural product from Tropaeolum majus.
PubMed:	Effect of alkyl chain length on inhibition of N-nitrosomethylbenzylamine-induced esophageal tumorigenesis and DNA methylation by isothiocyanates.
PubMed:	Forward and reverse catalysis and product sequestration by human glutathione S-transferases in the reaction of GSH with dietary aralkyl isothiocyanates.
PubMed:	Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29.
PubMed:	Some aspects of reactions of benzyl isothiocyanate with bovine sarcoplasmic proteins.
PubMed:	Chemoprevention by isothiocyanates.
PubMed:	Cytotoxic and clastogenic effects of benzyl isothiocyanate towards cultured mammalian cells.
PubMed:	Lung tumor induction in A/J mice by the tobacco smoke carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene: a potentially useful model for evaluation of chemopreventive agents.
PubMed:	Isolation and structure elucidation of new nitrile and mustard oil glycosides from Moringa oleifera and their effect on blood pressure.
PubMed:	Inhibitory effects of benzyl thiocyanate and benzyl isothiocyanate on methylazoxymethanol acetate-induced intestinal carcinogenesis in rats.
PubMed:	Effects of isothiocyanate alkyl chain-length on hamster liver cytochrome P-450 activity.
PubMed:	Effects of isothiocyanates on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and benzo[a]pyrene by hamster and rat liver microsomes.
PubMed:	Effects of isothiocyanates on tumorigenesis by benzo[a]pyrene in murine tumor models.
PubMed:	Inhibitory effects of benzyl isothiocyanate and benzyl thiocyanate on diethylnitrosamine-induced hepatocarcinogenesis in rats.
PubMed:	Radioimmunolocalization of metastatic breast carcinoma using indium-111-methyl benzyl DTPA BrE-3 monoclonal antibody: phase I study.
PubMed:	The clastogenic effects of isothiocyanates.
PubMed:	Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice.
PubMed:	Modulation of carcinogen-induced polyoma DNA-replication by organoselenium and organosulfur chemopreventive agents.
PubMed:	Modifying effects of benzyl isothiocyanate and benzyl thiocyanate on DNA synthesis in primary cultures of rat hepatocytes.
PubMed:	Reversed-phase high-performance liquid chromatographic separation of the stereoisomers of labetalol via derivatization with chiral and non-chiral isothiocyanate reagents.
PubMed:	In vitro stability of EDTA and DTPA immunoconjugates of monoclonal antibody 2G3 labeled with indium-111.
PubMed:	Structure-function relationships in indium-111 radioimmunoconjugates.
PubMed:	Subacute oral toxicity study of benzyl isothiocyanate in rats.
PubMed:	Hepatobiliary delivery of polyaminopolycarboxylate chelates: synthesis and characterization of a cholic acid conjugate of EDTA and biodistribution and imaging studies with its indium-111 chelate.
PubMed:	Characterization of antibody-chelator conjugates: determination of chelator content by terbium fluorescence titration.
PubMed:	Inhibition of tobacco-specific nitrosamine 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) tumorigenesis with aromatic isothiocyanates.
PubMed:	Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates.
PubMed:	Inhibition of carcinogenesis by minor anutrient constituents of the diet.
PubMed:	Effect of dietary aromatic isothiocyanates fed subsequent to the administration of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone on lung tumorigenicity in mice.
PubMed:	Inhibition of tobacco-specific nitrosamine 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumors and DNA methylation in F344 rats and A/J mice by phenethyl isothiocyanate.
PubMed:	Inhibition of carcinogenesis by naturally-occurring and synthetic compounds.
PubMed:	Ethylene-like activity of isocyanides.
PubMed:	Effects of alkyl chain length on the inhibition of NNK-induced lung neoplasia in A/J mice by arylalkyl isothiocyanates.
PubMed:	Effects of aromatic isothiocyanates on tumorigenicity, O6-methylguanine formation, and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung.
PubMed:	Induction of glutathione S-transferase, placental type in T9 glioma cells by dibutyryladenosine 3',5'-cyclic monophosphate and modification of its expression by naturally occurring isothiocyanates.
PubMed:	Reversed-phase liquid chromatographic separation of enantiomeric and diastereomeric bases related to chloramphenicol and thiamphenicol.
PubMed:	Characterization of benzyl isothiocyanate and phenyl acetonitrile from papayas by mass spectrometry.
PubMed:	Detoxification of isothiocyanate allelochemicals by glutathione transferase in three lepidopterous species.
PubMed:	Studies on the metabolism and excretion of benzyl isothiocyanate in man.
PubMed:	Differential induction of rat hepatic glutathione S-transferase isoenzymes by hexachlorobenzene and benzyl isothiocyanate. Comparison with induction by phenobarbital and 3-methylcholanthrene.
PubMed:	Inhibitory effects of benzyl isothiocyanate administered shortly before diethylnitrosamine or benzo[a]pyrene on pulmonary and forestomach neoplasia in A/J mice.
PubMed:	Cytomorphological changes in liver cells exposed to allyl and benzyl isothiocyanate and their cysteine and glutathione conjugates.
PubMed:	Glutathione- and cysteine-mediated cytotoxicity of allyl and benzyl isothiocyanate.
PubMed:	Induction of DT-diaphorase by anticarcinogenic sulfur compounds in mice.
PubMed:	Effects of disulfiram, diethyldithiocarbamate, bisethylxanthogen, and benzyl isothiocyanate on glutathione transferase activities in mouse organs.
PubMed:	Investigations into the possible regulation of negative gravitropic curvature in intact Avena sativa plants and in isolated stem segments by ethylene and gibberellins.
PubMed:	Antiasthmatic effects of onion extracts--detection of benzyl- and other isothiocyanates (mustard oils) as antiasthmatic compounds of plant origin.
PubMed:	Effects of dietary compounds on alpha-hydroxylation of N-nitrosopyrrolidine and N'-nitrosonornicotine in rat target tissues.
PubMed:	Quantitation of a bioactive metabolite in undisturbed rhizosphere-Benzyl isothiocyanate fromCarica papaya L.
PubMed:	Postharvest Variation in Cell Wall-Degrading Enzymes of Papaya (Carica papaya L.) during Fruit Ripening.
PubMed:	The metabolism of benzyl isothiocyanate and its cysteine conjugate in guinea-pigs and rabbits.
PubMed:	Enhancement of glutathione S-transferase activity of the esophagus by phenols, lactones, and benzyl isothiocyanate.
PubMed:	Glutathione S-transferase activity: enhancement by compounds inhibiting chemical carcinogenesis and by dietary constituents.
PubMed:	Inhibition of carcinogen-induced neoplasia by sodium cyanate, tert-butyl isocyanate, and benzyl isothiocyanate administered subsequent to carcinogen exposure.
PubMed:	Enhancement of glutathione S-transferase activity of the mouse forestomach by inhibitors of Benzo[a]pyrene-induced neoplasia of the forestomach.
PubMed:	Inhibition of carcinogenic effects of polycyclic hydrocarbons by benzyl isothiocyanate and related compounds.
PubMed:	The metabolism of benzyl isothiocyanate and its cysteine conjugate.
PubMed:	Inhibition of papain by isothiocyanates.
PubMed:	Inhibition of ethylene evolution in papaya pulp tissue by benzyl isothiocyanate.
PubMed:	Bacterial degradation of benzyl isothiocyanate.
PubMed:	Control of encephalitis in laboratory monkeys by benzyl isothiocyanate.