musk ketone
4-tert-butyl-2,6-dimethyl-3,5-dinitroacetophenone
 
Notes:
increases activity of glutathione s-transferase and thus may prove to be useful cancer chemoprotectant. Listed in the EAFUS Food Additive Database (Jan 2001)
  • Associate Allied Chemicals
    • Associate Allied Chemicals
      Quality, Service and Values
      Our aim is to become a reliable one-stop shop for our customers.
      Distributor and Agents of high quality raw materials for the fragrance, flavour and cosmetic industry. Partnering and sourcing raw materials directly from some of the best recognised names to provide consistent quality to our esteemed customers.
      Email: Info
      Email: Sachin Gandhi
      Voice: +91 22 2419 8800
      Fax: +91 22 2413 5786
      About
      Product(s):
      Musk Ketone
       
  • Augustus Oils
    • Augustus Oils Ltd
      The Premier Supplier
      Augustus Oils Ltd, in harmony with nature - to present it at its best...
      A wealth of experience, expertise and knowledge has allowed Augustus to bridge the gulf in expectation and trust between growers and users of natural ingredients. The Company works in partnership with customers on the one hand, and growers, farmers and distillers on the other. Both users and producers can then focus on exactly what they do best, while skilled Augustus technicians closely monitor and control the delivered product. This ensures users can have the confidence that they will receive the best raw materials suited to their requirements.
      Email: Enquiries
      Email: Sales
      Email: web site enquiries
      Voice: +44 (0)1420 590555
      Fax: +44 (0)1420 592420
      Services
      Product(s):
      Musk Ketone
       
  • Berjé
    • Berje Inc.
      Where the world comes to its senses
      Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.
      Berjé is a family-owned business that has been in operation for six decades. The company's origins and strength lie in a profound understanding of the supply and the quality of the diverse raw materials consumed by the flavor and fragrance industries. This base was expanded upon more than two decades ago to include fragrance production. The company's unparalleled raw material expertise is focused on the supply of essential oils and aromatic chemicals. This is supported by our long-standing relationships with a worldwide fabric of producers ensuring the greatest prospects for uninterrupted supply in markets that are often volatile and unpredictable.
      Email: For Information
      Email: For Sales
      Voice: 973-748-8980
      Fax: 973-680-9618
      Instagram
      Linkedin
      Flavor Ingredients
      Fragrance Ingredients
      Functional Ingredients
      Media
      Products List: View
      Product(s):
      Musk Ketone
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
      Email: Marketing
      US Email: Marketing
      Email: Sales
      US Email: Sales
      Voice: 1-631-485-4226
      Fax: 1-631-614-7828
      US Voice: 1-631-485-4226
      US Fax: 1-631-614-7828
      Europe44-203-286-1088
      Facebook
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      Product(s):
      81-14-1 Musk Ketone 98%
       
  • ECSA Chemicals
    • ECSA Chemicals
      Human Chemistry
      ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of the largest distributors worldwide.
      ECSA Chemicals is the largest Swiss-owned company in terms of warehouses for the distribution of chemical products. We have been distributing chemical products for over 100 years and we have a special interest in protecting the environment and in the safety of our facilities and collaborators.
      Established in 1913 as a small grocery store, in its over 100 years of activity ECSA Chemicals has become one of the most important Swiss-owned distributors of chemical products. The company, which is active in international distribution and trading, is organised into industrial segments that are managed by teams of specialists and experts. They guarantee professional and customised consultancy and services. With our experience, we can rapidly and safely connect you with the best suppliers on the market, providing you with a complete search, consulting and assistance service. The focus of our approach and operations is you, our customers. We strive every day to find the best products that satisfy your needs as quickly as possible. Your satisfaction is our greatest success. WHY CHOOSE ECSA? EXPERIENCE We have been working for 100 years. QUALITY We have obtained many certifications (ISO, SQAS, GDP, Responsible Care, Bio-Inspecta, RSPO, etc.). We guarantee full compliance with the current laws and continuous training for our staff. SAFETY We constantly carry out risk analyses for each infrastructure, defining safety levels and implementing corrective measures promptly wherever they are needed. WIDESPREAD DISTRIBUTION We have warehouses in strategic locations to supply goods to Switzerland and to the rest of the world. STORAGE CAPACITY The 3 ECSA-owned warehouses guarantee considerable storage area and capacity in each warehouse, with full availability of products (base chemicals and speciality chemicals). SPEED Presence all over the country, staff dedicated to sourcing raw materials and considerable storage capacity guarantee that goods are rapidly obtained and supplied. CONSULTANCY Our specialists - in-depth knowledge of the market and products allows us to provide full consulting services, from the purchase to the supply of raw materials.
      Email: Info
      Email: Sales
      Email: Trading
      Email: Maintenance
      Email: Energy
      Voice: +41 91 695 88 00
      Fax: +41 91 695 88 01
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      ECSA Trade
      ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
      Products List: View
      Product(s):
      MP-017988 MUSK KETONE
       
  • Fleurchem
    • Fleurchem, Inc.
      Have A Flavorful Day
      A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.
      Operating out of the 200,000 sq. ft., former Hercules/PFW facility in Middletown, NY; Fleurchem produces a full range of natural isolates, synthetic chemicals & specialities, essential oils and flavors. Additionally, the company performs toll manufacturing, as well as custom chemical synthesis for a wide range of clients.
      Email: Information
      US Voice: 845-341-2100
      US Fax: 845-341-2121
      Product(s):
      musk ketone
       
  • Foreverest Resources
    • Foreverest Resources Ltd.
      Leading pine based chemicals supplier
      Supplying turpentine based and natural/extracted flavor & fragrance ingredients.
      FOREVERESTA® F&F RAW MATERIALS is a range of natural extracts and synthetic aroma chemicals based on the rich material resources and great supply network from China, which was applied for specialty chemicals industry. The markets cover application areas on food, beverage, custom fragrance, fine perfume, personal care, cosmetics, etc.
      Foreverest Resources Ltd. is a materials supplier, exporting gum turpentine based, terpene derivertives and natural/extracted monomers and intermediates from China since 1988. We offers high quality raw materials for flavors and fragrances synthetic manufacturing in the world.
      Email: Info
      Email: Sales
      Voice: +86 (0)592 5105533
      Fax: +86 (0)592 5151667
      foreverest Skype Skype
      Linkedin
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      Products List: View
      Product(s):
      Musk Ketone
       
  • Global Essence
    • Global Essence Inc.
      Preferred Partner
      Accommodate each customers unique needs.
      Global Essence was founded in 1993 as a two person operation servicing regional customers in the New York/ New Jersey area. In the twenty years since, it has grown into a multinational operation with offices in the US, UK, and Singapore. These offices allow Global to provide regional support to its customers worldwide. As the world continues become more connected, this approach positions Global to continue to offer the highest quality products and experience to all of its customers.
      Email: Info
      US Email: Info
      Voice: +44 (0) 1279 876666
      Fax: +44 (0)1279 876646
      US Voice: 001 732 677 1100
      US Fax: 001 732 677 1107
      Blog
      Press Release
      News
      Product(s):
      Musk Ketone
       
  • Indukern F&F
  • Jiangyin Healthway
    • Jiangyin Healthway International Trade Co., Ltd
      Independent Ingredients Supplier
      We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
      Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals.
      Email: Info
      Email: Sales
      Voice: 86-510-86023169
      Fax: 86-510-86023170
      Mobile0086-13093133011
      Services
      Biochemical
      Natural Food Colour
      New functional food ingredients
      Product(s):
      HLW-FC013 Musk Ketone
      HLW-FC048 Ketone musk
       
  • Lluch Essence
    • Lluch Essence S.L.
      A family company dedicated to sales and distribution
      Flexibility, availability, price and quality.
      Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world.
      Email: Info
      Voice: 34 93 379 38 49
      Fax: 34 93 370 65 04
      Linkedin
      Product(s):
      MUSK KETONE 0,1%MAX MUSK XYLOL
       
  • M&U International
    • M&U International LLC
      Steady supply & demand
      Meeting customers increasing demands at home as well as abroad.
      M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers.
      Email: Sales
      US Email: Sales
      Voice: +86-21-32515501 60762991 60762992
      Fax: +86-21-32515502 64204960
      US Voice: 908-359-9000
      US Fax: 908-359-9002
      News
      Product(s):
      A0119 Musk Ketone
       
  • Moellhausen
  • OQEMA
    • OQEMA
      With a focus on providing the highest level of service
      OQEMA has established itself at the forefront of the global chemical industry.
      The guiding principles of OQEMA have always been to establish long term relationships with customers and suppliers alike to build sustainable and profitable business for all parties. Through OQEMA’s business divisions the company tailors products and services to better support and service our customers requirements. This structure also allows the company to focus its marketing campaigns more effectively to certain industries. Over the last decade OQEMA has achieved strong growth as a result of the expansion of our business model. Going forward, the company will be expanding this business model into existing and new strategic territories.
      Email: Contact Us:
      US Email: Dean Matienzo
      Email: Sales
      US Email: Dean Matienzo - Sales Manager
      Voice: +44 1993 843081
      Fax: +44 1993 841261
      US Voice: +1 973 886 3778
      US Fax: +1 973 346 1106
      Linkedin
      Website
      Global Distribution
      Product(s):
      Musk Ketone
      Musk Ketone Super (<0.1% MX)
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
      US Email: Sales
      US Voice: (973) 740-2300
      US Fax: (973) 740-1839
      Product(s):
      13-83000 MUSK KETONE
       
  • PerfumersWorld
    • PerfumersWorld Ltd.
      feeeel... the smell!
      The one-stop resource for the creative perfumer.
      No minimum orders. Aroma chemicals, essential oils, isolates, pheremones, absolutes, resinoids, FleuressenceTM key bases, PWx FactorTM, solubilizers, kits, creation systems, workshops, training, distance learning, The PerfumersWorld Perfumer's Studio, The Perfumer’s Formulation Bulletin, perfumery software, bespoke creation, analysis, consultancy, project counselling, trouble-shooting, unperfumed product bases, bottles, smelling strips, scales, distillation, equipment and inspiration!
      Email: Enquiries
      Email: Sales
      Voice: +66(0)2-99-800-80
      Fax: +66(0)2-99-800-80
      PerfumersWorld Skype Skype
      Facebook
      Twitter
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      Youtube
      Resources
      Software: Perfumer's Workbook
      Product(s):
      1XU00308 Musk Ketone
      Blends-well-with - +Curcuma +Labdanum +Costus Root +Copaiba +Clary Sage Animal-notes Ionone Cinnamic Alcohol Gums
       
      5XU07864 Musk ketone 10% in DEP
      5XU09977 Musk ketone 10% in DPG
       
  • Prodasynth
    • Prodasynth
      PRODUCTEUR PAR ESSENCE
      Chemical specialist in manufacturing, distributing and sourcing of tailor-made ingredients for the Flavour & Fragrance industry.
      Today we are also proud to say, we have created an important range of Natural Molecules which can be found in our Raw Material Compendium. The versatility of our small but efficient structure is one of our main strengths when trying to fulfill our clients' requirements.
      Email: Info:
      Email: Sales Team Prodasynth
      Voice: (33) 4 93 09 00 11
      Fax: (33) 4 22 13 07 38
      New Catalog
      Products List: View
      Product(s):
      MUSK KETONE (> 99%)
       
  • Sigma-Aldrich
  • SRS Aromatics
    • SRS Aromatics Ltd
      For over 25 years
      Bringing flavour and fragrance into your world.
      As suppliers / distributors of ingredients to the fragrance and flavour industries, our goal is to provide high quality materials at competitive prices with an exceptional level of service. Established in 1984, SRS Aromatics Ltd is an independent family owned business which has become very well-respected within the fragrance and flavour industry as a reliable and trustworthy partner. Over the years this has allowed the company to develop strong relationships with many global manufacturers; several of whom we represent in the UK. A core aim of our business is to work extremely closely with both our suppliers and customers to maximise service levels with minimum disruption to supply.
      Email: Info
      Email: Sales
      Voice: +44 (0) 1284 704076
      Fax: +44 (0) 1284 760819
      Twitter
      Linkedin
      News
      Product(s):
      MUSK KETONE < 0.1 % XYLOL
       
  • Sunaux International
    • Sunaux International
      Buy With Confidence
      We have industry leading processes and procedures to ensure nothing but the most reliable product.
      Sunaux International was founded in 2012 by the owner Mr.John Felton after spending 18 years involved in developing global business in the aromatic chemicals, fragrance and flavour compounds business.
      Email: John Felton
      Email: Stephen Zhou (Sales)
      Voice: 0512-57995626
      Fax: 0512-57570299
      Sales0512-57995626
      Sales0512-57570299
      News
      Product(s):
      A0127 Musk Ketone
       
  • The John D. Walsh Company
    • The John D. Walsh Company, Inc
      Suppliers Since 1942
      Supplying the fragrance and flavor industry with high quality products.
      The John D. Walsh Company, Inc. has evolved from its beginnings as an agent/broker into a distributor of essential oils, aroma chemicals, concretes and absolutes. We currently represent the following companies, as their North American distributor: Destilerias Munoz Galvez, S.A. International Flavors & Fragrances PFW Aroma Chemicals B.V. Innospec Widnes Limited Hydrodiffusion de Guatemala, S. A. DSM Nutritional Products The John D. Walsh Company, Inc. is proud to be a founding member of IFEAT, an active member of IFRA, North America, and a corporate sponsor of the WFFC.
      Email: Information
      Email: Sales
      Email: Firmenich Flavor inquiries
      Voice: 973-962-1400
      Fax: 973-962-1557
      Firmenich Flavor Phone:973-962-1888
      Firmenich Flavor Fax:973-962-1898
      History
      Product(s):
      Musk Ketone
      SDS
       
  • The Lermond Company
    • The Lermond Company
      Your Sourcing Resource
      The Lermond family has been sourcing raw materials for the flavor and fragrance industry for nearly 7 decades.
      The Lermond Company is a women-owned distributor of raw materials primarily servicing the flavor and fragrance industry. For three generations, members of the Lermond family have been integral sourcing partners for the North American flavor and fragrance industry. We supply high quality essential oils, aroma chemicals, absolutes, concretes, resinoids and floral waters from around the world to the global industry.
      Email: Info
      Email: Tara
      Email: Erica
      Voice: 201-896-3300
      Fax: 201-623-2910
      Facebook
      Instagram
      Linkedin
      Product(s):
      42065 MUSK KETONE
       
  • R C Treatt & Co Ltd
    • R C Treatt and Co Ltd
      Innovative ingredient solutions
      World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.
      We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products.
      Email: Enquiries
      US Email: Enquiries
      Voice: +44 (0) 1284 702500
      Fax: +44 (0) 1284 703809
      US Voice: +1 863 668 9500
      US Fax: +1 863 668 3388
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      Product(s):
      Musk Ketone
       
  • Ernesto Ventós
  • WholeChem
    • WholeChem, LLC
      Connecting Innovators To the Building Blocks Of the Universe
      Custom manufacturer and distributor of specialty ingredients. We make global local.
      SQF-Certified Supplier
      We owe our success to our integrity, our dedication to the industry, and our commitment to our clients. We invite your inquiries regarding our current product list and any other products you may be having trouble sourcing.
      Email: Info
      Email: Orders
      Voice: +1 (262) 995.8668
      Certification
      Our Services
      Products List: View
      Product(s):
      Musk Ketone
       
Synonyms   Articles   Notes   Search
Fragrance Demo Formulas
CAS Number: 81-14-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 201-328-9
FDA UNII: 483V3E1L6J
Nikkaji Web: J3.856C
Beilstein Number: 2062638
MDL: MFCD00024271
XlogP3-AA: 3.70 (est)
Molecular Weight: 294.30746000
Formula: C14 H18 N2 O5
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome, Edge or firefox)
Category: fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
FDA Mainterm (SATF):81-14-1 ; MUSK, KETONE
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: yellow powder (est)
Assay: 98.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 135.00 to  139.00 °C. @ 760.00 mm Hg
Boiling Point: 395.00 °C. @ 0.00 mm Hg
Vapor Pressure: 0.000012 mmHg @ 25.00 °C. (est)
Flash Point: 212.00 °F. TCC ( 100.00 °C. )
logP (o/w): 2.510 (est)
Soluble in:
 alcohol
 paraffin oil
 water, 0.6365 mg/L @ 25 °C (est)
 8.9 gms to 100 gms methyl carbitol
 25.4 gms to 100 gms benzyl benzoate
 16.5 gms to 100 gms diethyl phthalate
 18.6 gms to 100 gms dimethyl phthalate
 1.8 gms to 100 gms alcohol (95%)
Insoluble in:
 water
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: musk
 
Odor Strength: medium
 
Substantivity: 400 hour(s) at 20.00 % in dipropylene glycol
 
 fatty  musk  soapy  dry  floral  powdery  
Odor Description:
at 10.00 % in benzyl benzoate. 
fatty musk soapy dry floral powdery
Luebke, William tgsc, (1986)
 
Odor and/or flavor descriptions from others (if found).
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: fragrance
perfuming agents
Synonyms   Articles   Notes   Search   Top
Suppliers:
Anhui Haibei
Musk Ketone
Odor: Strong musk odor, similar to natural musk
Associate Allied Chemicals
Musk Ketone
About
Augustus Oils
Musk Ketone
Services
Berjé
Musk Ketone
Media
BOC Sciences
For experimental / research use only.
Musk Ketone 98%
Creatingperfume.com
Musk Ketone
ECSA Chemicals
MUSK KETONE
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
Ernesto Ventós
MUSK KETONE (MUSK XYLOL < 0,1%)
Odor: SWEET, PERSISTENT, MUSK TYPE
Fleurchem
musk ketone
Foreverest Resources
Musk Ketone
Fuzhou Farwell
Musk Ketone
Global Essence
Musk Ketone
Indenta Group
Musk Ketone
Indukern F&F
MUSK KETONE EXTRA
Indukern F&F
MUSK KETONE
Jiangyin Healthway
Ketone musk
New functional food ingredients
Jiangyin Healthway
Musk Ketone
John Kellys (London)
Musk Ketone
K.L. Koh Enterprise
MUSK KETONE
Lluch Essence
MUSK KETONE 0,1%MAX MUSK XYLOL
M&U International
Musk Ketone
Moellhausen
MUSK KETONE (MX 0,1%max)
Moellhausen
MUSK KETONE 10%DPG
OQEMA
Musk Ketone Super (<0.1% MX)
OQEMA
Musk Ketone
Pearlchem Corporation
Musk Ketone
Penta International
MUSK KETONE
PerfumersWorld
Musk ketone 10% in DEP
PerfumersWorld
Musk ketone 10% in DPG
PerfumersWorld
Musk Ketone
Odor: natural musk dry powdery nitro musk floral-fruity Sweet
Use: Blends-well-with - +Curcuma +Labdanum +Costus Root +Copaiba +Clary Sage Animal-notes Ionone Cinnamic Alcohol Gums
Perfumery Laboratory
Musk Ketone
Odor: Sweet, fruity-floral, powdery musky
Phoenix Aromas & Essential Oils
Musk Ketone
Prodasynth
MUSK KETONE
(> 99%)
Odor: SWEET, PERSISTENT, MUSK TYPE
R C Treatt & Co Ltd
Musk Ketone
Reincke & Fichtner
Musk Ketone
Sigma-Aldrich
Musk ketone, ≥98%
Certified Food Grade Products
SRS Aromatics
MUSK KETONE < 0.1 % XYLOL
Sunaux International
Musk Ketone
The John D. Walsh Company
Musk Ketone
The Lermond Company
MUSK KETONE
The Perfumers Apprentice
Musk Ketone
Odor: Sweet and very tenacious musky
Vistachem
Musk Ketone
WholeChem
Musk Ketone
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xn N - Harmful, Dangerous for the environment.
R 02 - Risk of explosion by shock, friction, fire or other sources of ignition.
R 40 - Possible risks of irreversable effects.
R 52/53 - Harmful to qauatic organisms, may cause long-term adverse effects in the aquatic environment.
S 02 - Keep out of the reach of children.
S 36/37 - Wear suitable protective clothing and gloves.
S 46 - If swallowed, seek medical advice immediately and show this container or label.
S 60 - This material and its container must be disposed of as hazardous waste.
S 61 - Avoid release to the environment. Refer to special instructions/safety data sheet.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  > 10000 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 877, 1975.

unreported-rabbit LD50  10000 mg/kg
Bulletin of Environmental Contamination and Toxicology. Vol. 26, Pg. 656, 1981.

Dermal Toxicity:
skin-rabbit LD50 > 10000 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 877, 1975.

Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA fragrance material specification:
 Musk ketone should only be used if it contains less than 0.1% of musk xylene.
IFRA: View Standard
 
Recommendation for musk ketone flavor usage levels up to:
 not for flavor use.
Synonyms   Articles   Notes   Search   Top
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 81-14-1
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 6669
National Institute of Allergy and Infectious Diseases: Data
SCCNFP: opinion
WGK Germany: 2
 1-(4-tert-butyl-2,6-dimethyl-3,5-dinitrophenyl)ethanone
Chemidplus: 0000081141
EPA/NOAA CAMEO: hazardous materials
RTECS: KM5775841 for cas# 81-14-1
Synonyms   Articles   Notes   Search   Top
References:
 1-(4-tert-butyl-2,6-dimethyl-3,5-dinitrophenyl)ethanone
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 81-14-1
Pubchem (cid): 6669
Pubchem (sid): 134972653
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
CHEMBL: View
HMDB (The Human Metabolome Database): HMDB31865
FooDB: FDB008549
ChemSpider: View
Wikipedia: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
No odor group found for these
 atractylis absoluteFR
aldehydic
 aldehydic fragranceFR
amber
 amber powdery floral fragranceFR
 cistus ladaniferus resinoidFL/FR
animal
 civet absoluteFL/FR
balsamic
 abies alba needle oilFL/FR
 benzyl cinnamateFL/FR
 copaiba balsam oilFL/FR
 fir needle oil siberiaFL/FR
citrus
 bergamot vanilla specialtyFR
floral
isobutyl salicylateFL/FR
 cyclamen aldehydeFL/FR
 daisy fragranceFR
 dimethyl anthranilateFL/FR
 heliotrope fragranceFR
 heliotrope specialtyFR
(E)-beta-iononeFL/FR
 methyl citronellateFL/FR
alpha-isomethyl ionone (50% min.)FL/FR
bitter orangeflower water absoluteFL/FR
 orris rhizome resinoid (iris pallida)FL/FR
 orris rhizome resinoid replacerFR
 petitgrain mandarin oil terpenelessFL/FR
 rhodinyl acetateFL/FR
fruity
isoamyl octanoateFL/FR
herbal
 acorus calamus root oilFR
 clary sage oil franceFL/FR
 lavender absolute bulgariaFL/FR
musk
 musk amberolFR
 musk indanoneFR
6,7,8,9-tetrahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazolineFR
orris
beta-methyl iononeFL/FR
powdery
 midnight passion fragranceFR
spicy
 turmeric root oil chinaFL/FR
tonka
 coumarinFR
vanilla
 heliotropyl alcoholFL/FR
waxy
9-decenoic acidFL/FR
 myristic acidFL/FR
woody
 amber carbinolFR
 amber woody specialtyFR
 cedarwood oil virginiaFR
isolongifolene epoxideFR
 sandal pentenoneFR
4,6,11-trimethyl-5-oxatricyclo(6.2.2.0*4,9*)dodec-6-eneFR
 
For Flavor
 
No flavor group found for these
 cistus ladaniferus resinoidFL/FR
 heliotropyl alcoholFL/FR
animal
 civet absoluteFL/FR
balsamic
 copaiba balsam oilFL/FR
 fir needle oil siberiaFL/FR
cooling
isobutyl salicylateFL/FR
floral
 methyl citronellateFL/FR
beta-methyl iononeFL/FR
alpha-isomethyl ionone (50% min.)FL/FR
bitter orangeflower water absoluteFL/FR
 orris rhizome resinoid (iris pallida)FL/FR
 rhodinyl acetateFL/FR
fruity
isoamyl octanoateFL/FR
 dimethyl anthranilateFL/FR
 petitgrain mandarin oil terpenelessFL/FR
green
 cyclamen aldehydeFL/FR
herbal
 clary sage oil franceFL/FR
 lavender absolute bulgariaFL/FR
spicy
 benzyl cinnamateFL/FR
 turmeric root oil chinaFL/FR
terpenic
 abies alba needle oilFL/FR
waxy
9-decenoic acidFL/FR
 myristic acidFL/FR
woody
(E)-beta-iononeFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 a suma 
 abroniaFR
 acaciaFR
 amberFR
 ambreneFR
 amour-amour 
 animalFR
 arpege 
 baby powderFR
 balsamFR
 bellodgia 
 cabochard 
 carnationFR
 cedarFR
 chanel #5 
 chypreFR
 cinq fleurs forvil 
 crabapple blossomFR
 dilleniaFR
 elder flowerFR
 emeraude 
 fernFR
 floralFR
 gardeniaFR
 genetFR
 honeysuckleFR
 hugoniaFR
 japan flowersFR
 jasminFR
 jicky 
 joy 
 juniper berryFR
 l'air du temps 
 leatherFR
 mimosaFR
 mossFR
 muskFR
 my sin 
 narcissusFR
 nemesia 
 orange blossomFR
 orientalFR
 poppy red poppyFR
 powderFR
 presence 
 rose red roseFR
 sandalwoodFR
 scandal 
 shalimar 
 tabu 
 violetFR
 vol de nuit 
 wallflowerFR
 windsor soapFR
 wisteriaFR
 woodyFR
 ylang ylangFR
 zibelineFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 not found in nature
Synonyms   Articles   Notes   Search   Top
Synonyms:
 acetophenone, 4'-tert-butyl-2',6'-dimethyl-3',5'-dinitro-
1-acetyl-4-(tert-butyl)-2,6-dimethyl-3,5-dinitrobenzene
1-(4-tert-butyl-2,6-dimethyl-3,5-dinitro-phenyl)-ethanone
4-tert-butyl-2,6-dimethyl-3,5-dinitroacetophenone
1-(4-tert-butyl-2,6-dimethyl-3,5-dinitrophenyl)ethanon
1-(4-tert-butyl-2,6-dimethyl-3,5-dinitrophenyl)ethanone
4'-tert-butyl-2',6'-dimethyl-3',3'-dinitroacetophenone
4'-tert-butyl-2',6'-dimethyl-3',5'-dinitroacetophenone
4-tert-butyl-3,5-dinitro-2,6-dimethyl acetophenone
4-tert-butyl-3,5-dinitro-2,6-dimethylacetophenone
1-(4-(tert-butyl)-2,6-dimethyl-3,5-dinitrophenyl)ethanone
1-[4-(tert-butyl)-2,6-dimethyl-3,5-dinitrophenyl]ethan-1-one
1-(4-(1,1-dimethyl ethyl)-2,6-dimethyl-3,5-dinitrophenyl) ethanone
2,6-dimethyl-3,5-dinitro-4-tert-butylacetophenone
1-[2,6-dimethyl-4-(2-methyl-2-propanyl)-3,5-dinitrophenyl]ethanone
1-(4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl) ethanone
1-(4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl)ethanone
1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]ethanone
3,5-dinitro-2,6-dimethyl-4-tert-butyl acetophenone
2,6-dinitro-3,5-dimethyl-4-acetyl-tert-butyl benzene
 ethanone, 1-(4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl)-
 ethanone, 1-[4- (1,1-dimethylethyl)-2,6-dimethyl-3, 5-dinitrophenyl]-
 ethanone, 1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]-
 ketone moschus
 musk ketone extra
 muskketone
Synonyms   Articles   Notes   Search   Top
Articles:
Info: MUSK
PubMed: [Determination of trace musk xylene and musk ketone in aquatic products by multiple adsorption synchronous purification-gas chromatography-mass spectrometry].
PubMed: Headspace stir bar sorptive extraction followed by thermal desorption and gas chromatography with mass spectrometry to determine musk fragrances in sludge samples without sample pretreatment.
PubMed: Pilot study on levels of chemical contaminants and porphyrins in Caretta caretta from the Mediterranean Sea.
PubMed: Development of stir-bar sorptive extraction-thermal desorption-gas chromatography-mass spectrometry for the analysis of musks in vegetables and amended soils.
PubMed: Analysis of 7 synthetic musks in cream by supported liquid extraction and solid phase extraction followed by GC-MS/MS.
PubMed: Simultaneous detection and quantification of select nitromusks, antimicrobial agent, and antihistamine in fish of grocery stores by gas chromatography-mass spectrometry.
PubMed: Comparison of embryo toxicity using two classes of aquatic vertebrates.
PubMed: [Determination of musk ketone in aquatic products by gas chromatography-mass spectrometry with dispersive solid phase extraction].
PubMed: Comprehensive monitoring of synthetic musk compounds from freshwater to coastal environments in Korea: with consideration of ecological concerns and bioaccumulation.
PubMed: Microextraction by packed sorbents combined with surface-enhanced Raman spectroscopy for determination of musk ketone in river water.
PubMed: Read-across estimates of aquatic toxicity for selected fragrances.
PubMed: Determination of polycyclic and nitro musks in environmental water samples by means of microextraction by packed sorbents coupled to large volume injection-gas chromatography-mass spectrometry analysis.
PubMed: [Determination of synthetic nitro-musks in cosmetics by gas chromatography coupled with negative chemical ionization-triple quadrupole mass spectrometry].
PubMed: [Effects of musk ketone at different concentrations on in vivo migration of exogenous rat bone marrow mesenchymal stem cells].
PubMed: Determination of synthetic musk compounds in indoor house dust by gas chromatography-ion trap mass spectrometry.
PubMed: [Determination of five synthetic musks in perfume by headspace solid-phase microextraction and gas chromatography-mass spectrometry].
PubMed: Spatial and seasonal distribution of synthetic musks in sewage treatment plants of Shanghai, China.
PubMed: Levels and distribution of synthetic musks and polycyclic aromatic hydrocarbons in sludge collected from Guangdong Province.
PubMed: Occurrence of synthetic musk fragrances in effluent and non-effluent impacted environments.
PubMed: The occurrence of synthetic musks in human breast milk in Sichuan, China.
PubMed: Identification of bound nitro musk-protein adducts in fish liver by gas chromatography-mass spectrometry: biotransformation, dose-response and toxicokinetics of nitro musk metabolites protein adducts in trout liver as biomarkers of exposure.
PubMed: Levels of synthetic musk fragrances in human milk from three cities in the Yangtze River Delta in Eastern China.
PubMed: [Occurrence of synthetic musks in human milk samples collected from Beijing].
PubMed: Transformation products and reaction kinetics of fragrances in advanced wastewater treatment with ozone.
PubMed: Antitumor and anti-invasive effects of diverse musk-fragrant macrocyclic ketones and their enhancement by hyperthermia.
PubMed: High-sensitivity analysis of six synthetic musks by ultra-performance liquid chromatography-atmospheric pressure photoionization-tandem mass spectrometry.
PubMed: Development of a stir bar sorptive extraction and thermal desorption-gas chromatography-mass spectrometry method for determining synthetic musks in water samples.
PubMed: Assessing combined toxicity of estrogen receptor agonists in a primary culture of rainbow trout (Oncorhynchus mykiss) hepatocytes.
PubMed: Occurrence of synthetic musk fragrances in human blood from 11 cities in China.
PubMed: Occurrence of synthetic musks in indoor dust from China and implications for human exposure.
PubMed: Challenge of false alarms in nitroaromatic explosive detection--a detection device based on surface-enhanced Raman spectroscopy.
PubMed: Seasonal occurrence and behavior of synthetic musks (SMs) during wastewater treatment process in Shanghai, China.
PubMed: Synthetic Musk Fragrances in a Conventional Drinking Water Treatment Plant with Lime Softening.
PubMed: Stir-bar-sorptive extraction and liquid desorption combined with large-volume injection gas chromatography-mass spectrometry for ultra-trace analysis of musk compounds in environmental water matrices.
PubMed: The interference of nitro- and polycyclic musks with endogenous and xenobiotic metabolizing enzymes in carp: an in vitro study.
PubMed: Occurrence of endocrine disrupting compounds, pharmaceuticals, and personal care products in the Han River (Seoul, South Korea).
PubMed: Simultaneous determination of trace polycyclic and nitro musks in water samples using optimized solid-phase extraction by gas chromatography and mass spectrometry.
PubMed: Inputs and distributions of synthetic musk fragrances in an estuarine and coastal environment; a case study.
PubMed: Synthetic musks in blood of healthy young adults: relationship to cosmetics use.
PubMed: Biological transformation, kinetics and dose-response assessments of bound musk ketone hemoglobin adducts in rainbow trout as biomarkers of environmental exposure.
PubMed: [Toxic effect of musk ketone based on the determinations of wheat (Triticum aestivum) seed germination and root elongation].
PubMed: Temporal trends of synthetic musk compounds in mother's milk and associations with personal use of perfumed products.
PubMed: Nitromusk compounds in San Francisco Bay sediments.
PubMed: Chub (Leuciscus cephalus) as a bioindicator of contamination of the Vltava River by synthetic musk fragrances.
PubMed: Concentrations of synthetic musk compounds in personal care and sanitation products and human exposure profiles through dermal application.
PubMed: Synthetic musk fragrances in human milk from the United States.
PubMed: Emerging pollutants in the North Sea in comparison to Lake Ontario, Canada, data.
PubMed: Optimization of a sensitive method for the determination of nitro musk fragrances in waters by solid-phase microextraction and gas chromatography with micro electron capture detection using factorial experimental design.
PubMed: Microwave-assisted solvent extraction of solid matrices and subsequent detection of pharmaceuticals and personal care products (PPCPs) using gas chromatography-mass spectrometry.
PubMed: Persistent organic pollutants, brominated flame retardants and synthetic musks in fish from remote alpine lakes in Switzerland.
PubMed: Synthetic musk fragrances in Lake Erie and Lake Ontario sediment cores.
PubMed: Determination of synthetic musk compounds in sewage biosolids by gas chromatography/mass spectrometry.
PubMed: Aquatic processes and systems in perspective.
PubMed: Synthetic musk fragrances in environmental Standard Reference Materials.
PubMed: Fate of endocrine-disruptor, pharmaceutical, and personal care product chemicals during simulated drinking water treatment processes.
PubMed: Analysis of neutral nitromusks in incenses by capillary electrophoresis in organic solvents and gas chromatography-mass spectrometry.
PubMed: Occurrence of synthetic musk fragrances in marine mammals and sharks from Japanese coastal waters.
PubMed: Simultaneous congener-specific determination of selected organochlorine compounds and nitro musks in human whole blood samples by solid-phase extraction and capillary gas chromatography with electron capture detection.
PubMed: Estrogenic activity of cosmetic components in reporter cell lines: parabens, UV screens, and musks.
PubMed: Characterization of allegedly musk-containing medicinal products in Taiwan.
PubMed: Further solid-phase microextraction-gas chromatography-mass spectrometry applications: "on-fibre" and aqueous photodegradation of nitro musks.
PubMed: [An experimental study on distribution of musk into the brain through blood brain barrier].
PubMed: Fatal attraction: synthetic musk fragrances compromise multixenobiotic defense systems in mussels.
PubMed: Formation of nitro musk adducts of rainbow trout hemoglobin for potential use as biomarkers of exposure.
PubMed: Synthetic musk toxicity to early life stages of zebrafish (Danio rerio).
PubMed: Synthetic musk fragrances in Lake Michigan.
PubMed: Dissipation of fragrance materials in sludge-amended soils.
PubMed: Determination of musk compounds in sewage treatment plant sludge samples by solid-phase microextraction.
PubMed: Polycyclic aromatic musk compounds in sewage treatment plant effluents of Canada and Sweden--first results.
PubMed: Inhibition of larval development of the marine copepod Acartia tonsa by four synthetic musk substances.
PubMed: Effects of four synthetic musks on the life cycle of the harpacticoid copepod Nitocra spinipes.
PubMed: Estrogenic activity of musk fragrances detected by the E-screen assay using human mcf-7 cells.
PubMed: Synthetic musks in the environment. Part 1: Species-dependent bioaccumulation of polycyclic and nitro musk fragrances in freshwater fish and mussels.
PubMed: Dermal absorption and disposition of musk ambrette, musk ketone and musk xylene in human subjects.
PubMed: Nitromusk compounds in women with gynecological and endocrine dysfunction.
PubMed: The impact of musk ketone on reproduction in zebrafish (Danio rerio).
PubMed: Musk ketone enhances benzo(a)pyrene induced mutagenicity in human derived Hep G2 cells.
PubMed: Evaluation of health risks caused by musk ketone.
PubMed: Determination of musk ambrette, musk xylol, and musk ketone in fragrance products by capillary gas chromatography with electron capture detection.
PubMed: Optimization of solid-phase microextraction for the gas chromatographic-mass spectrometric determination of synthetic musk fragrances in water samples.
PubMed: Contamination of human milk in Middle Hesse, Germany--a cross-sectional study on the changing levels of chlorinated pesticides, PCB congeners and recent levels of nitro musks.
PubMed: Analysis of nitro musk compounds and their amino metabolites in liquid sewage sludges using NMR and mass spectrometry.
PubMed: Kinetics of nitromusk compounds degradation in water by ultraviolet radiation and hydrogen peroxide.
PubMed: Nitro musks, nitro musk amino metabolites and polycyclic musks in sewage sludges. Quantitative determination by HRGC-ion-trap-MS/MS and mass spectral characterization of the amino metabolites.
PubMed: An in vivo mouse micronucleus assay on musk ketone.
PubMed: Subchronic inhalation studies of complex fragrance mixtures in rats and hamsters.
PubMed: Developmental toxicity studies of four fragrances in rats.
PubMed: Effects of musk xylene and musk ketone on rat hepatic cytochrome P450 enzymes.
PubMed: Dermal absorption and disposition of musk ambrette, musk ketone and musk xylene in rats.
PubMed: Polycyclic musk fragrances in the aquatic environment.
PubMed: Interactions of nitromusk parent compounds and their amino-metabolites with the estrogen receptors of rainbow trout (Oncorhynchus mykiss) and the South African clawed frog (Xenopus laevis).
PubMed: Toxicity of nitromusks in early lifestages of South African clawed frog (Xenopus laevis) and zebrafish (Danio rerio).
PubMed: Musk xylene and musk ketone amino metabolites in the aquatic environment.
PubMed: Levels of synthetic musks; bromocyclene and PCBs in eel (Anguilla anguilla) and PCBs in sediment samples from some waters of Berlin/Germany.
PubMed: GC-MS analysis of incenses for possible presence of allergenic nitromusks.
PubMed: Characterization of the effects of musk ketone on mouse hepatic cytochrome P450 enzymes.
PubMed: Environmental risk assessment of musk ketone and musk xylene in The Netherlands in accordance with the EU-TGD.
PubMed: Genotoxicity of nitro musks in the micronucleus test with human lymphocytes in vitro and the human hepatoma cell line Hep G2.
PubMed: Nitro musk compounds genotoxic activity : Genotoxicity testing of nitro musks with the SOS-chromotest and the sister-chromatid exchange test.
PubMed: Nitro musks are cogenotoxicants by inducing toxifying enzymes in the rat.
PubMed: An evaluation of genotoxicity tests with Musk ketone.
PubMed: Occurrence of nitro and non-nitro benzenoid musk compounds in human adipose tissue.
PubMed: A comparative study of five nitro musk compounds for genotoxicity in the SOS chromotest and Salmonella mutagenicity.
PubMed: [Mutagenicity, genotoxicity and cogenotoxicity of environmentally relevant nitro musk compounds].
PubMed: [Nitro-musk compounds in breast milk].
PubMed: Successful treatment of musk ketone-induced chronic actinic dermatitis with cyclosporine and PUVA.
PubMed: Isolation and biological evaluation of potential cancer chemopreventive agents from ambrette musk residue.
PubMed: Quantitation of the nitrosamine 2-ethylhexyl-4-(N-methyl-N-nitrosoamino) benzoate (NPABAO) in sunscreen products.
PubMed: 90-day dermal toxicity study and neurotoxicity evaluation of nitromusks in the albino rat.
PubMed: Photoallergic potential in the guinea-pig of the nitromusk perfume ingredients musk ambrette, musk moskene, musk xylene, musk ketone, and musk tibetene.
PubMed: Phototoxicity, photoallergy, and contact sensitization of nitro musk perfume raw materials.
PubMed: A simple method of qualitative analysis for musk ambrette, musk ketone and musk xylene in cologne.
PubMed: Contact allergy to photoproducts of musk ambrette.
PubMed: Thin layer chromatography and high pressure liquid chromatography of musk ambrette and other nitromusk compounds including photopatch studies.
PubMed: Testing with musk ambrette and congeners in a case of photosensitivity dermatitis and actinic reticuloid syndrome (PD/AR).
PubMed: Photosensitivity to musk ambrette.
PubMed: Identification of musk xylene and musk ketone in freshwater fish collected from the Tama River, Tokyo.
PubMed: Clinical testing of olfaction reassessed.
PubMed: Correlated odour threshold bimodality of two out of three synthetic musks.
PubMed: The structure of musk ketone and musk tibetene.
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