musk ambrette
2,4-dinitro-3-methyl-6-tert-butylanisole
 
Notes:
widely used fragrance implicated in contact photosensitivity.
  • Associate Allied Chemicals
    • Associate Allied Chemicals
      Quality, Service and Values
      Our aim is to become a reliable one-stop shop for our customers.
      Distributor and Agents of high quality raw materials for the fragrance, flavour and cosmetic industry. Partnering and sourcing raw materials directly from some of the best recognised names to provide consistent quality to our esteemed customers.
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      Product(s):
      Musk Ambrette
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
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      Product(s):
      83-66-9 Musk Ambrette
       
  • Fleurchem
    • Fleurchem, Inc.
      Have A Flavorful Day
      A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.
      Operating out of the 200,000 sq. ft., former Hercules/PFW facility in Middletown, NY; Fleurchem produces a full range of natural isolates, synthetic chemicals & specialities, essential oils and flavors. Additionally, the company performs toll manufacturing, as well as custom chemical synthesis for a wide range of clients.
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      US Voice: 845-341-2100
      US Fax: 845-341-2121
      Product(s):
      musk ambrette
       
  • Jiangyin Healthway
    • Jiangyin Healthway International Trade Co., Ltd
      Independent Ingredients Supplier
      We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
      Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals.
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      Product(s):
      HLW-FC049 Musk Ambrette
       
  • Lluch Essence
    • Lluch Essence S.L.
      A family company dedicated to sales and distribution
      Flexibility, availability, price and quality.
      Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world.
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      Voice: 34 93 379 38 49
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      Product(s):
      MUSK AMBRETTE
       
  • M&U International
    • M&U International LLC
      Steady supply & demand
      Meeting customers increasing demands at home as well as abroad.
      M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers.
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      A0118 Musk Ambrette
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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      13-82800 MUSK AMBRETTE
       
  • SRS Aromatics
    • SRS Aromatics Ltd
      For over 25 years
      Bringing flavour and fragrance into your world.
      As suppliers / distributors of ingredients to the fragrance and flavour industries, our goal is to provide high quality materials at competitive prices with an exceptional level of service. Established in 1984, SRS Aromatics Ltd is an independent family owned business which has become very well-respected within the fragrance and flavour industry as a reliable and trustworthy partner. Over the years this has allowed the company to develop strong relationships with many global manufacturers; several of whom we represent in the UK. A core aim of our business is to work extremely closely with both our suppliers and customers to maximise service levels with minimum disruption to supply.
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      MUSK AMBRETTE
       
  • Sunaux International
    • Sunaux International
      Buy With Confidence
      We have industry leading processes and procedures to ensure nothing but the most reliable product.
      Sunaux International was founded in 2012 by the owner Mr.John Felton after spending 18 years involved in developing global business in the aromatic chemicals, fragrance and flavour compounds business.
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      A0126 Musk Ambrette
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
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      Product(s):
      B1379 4-tert-Butyl-3-methoxy-2,6-dinitrotoluene >99.0%(GC)
       
Synonyms   Articles   Notes   Search
CAS Number: 83-66-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 201-493-7
FDA UNII: 55V150W8R6
Nikkaji Web: J11.610F
Beilstein Number: 1889437
MDL: MFCD00024268
CoE Number: 495
XlogP3-AA: 3.60 (est)
Molecular Weight: 268.26952000
Formula: C12 H16 N2 O5
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
FEMA Number: 2758-VOID
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):83-66-9 ; MUSK AMBRETTE--NLFG
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: pale yellow powder (est)
Assay: 98.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 85.00 °C. @ 760.00 mm Hg
Boiling Point: 369.32 °C. @ 760.00 mm Hg (est)
Congealing Point: 83.40 °C.
Vapor Pressure: 0.000025 mmHg @ 25.00 °C. (est)
Flash Point: > 220.00 °F. TCC ( > 104.44 °C. )
logP (o/w): 4.039 (est)
Soluble in:
 alcohol
 paraffin oil
 16.4 gms to 100 gms methyl carbitol
 50 gms to 100 gms benzyl benzoate
 36.7 gms to 100 gms diethyl phthalate
 32.6 gms to 100 gms dimethyl phthalate
 3.3 gms to 100 gms alcohol (95%)
 water, 2.107 mg/L @ 25 °C (est)
Stability:
 cream
 hair spray
 lipstick
 lotion
 powder
 shampoo
 soap
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Organoleptic Properties:
 
Odor Type: musk
 
Odor Strength: medium
 
Substantivity: 400 hour(s) at 20.00 % in benzyl benzoate
 
 musty  sweet  ambrette  seedy  
Odor Description:
at 10.00 % in benzyl benzoate. 
musty sweet ambrette seed
Luebke, William tgsc, (1984)
 
Odor and/or flavor descriptions from others (if found).
 
Perfumery Laboratory
MUSKUS AMBRETTES crystals (Musk Ambrette)
Odor Description: Sweet, musky, floral, with a pear shade and a bright note of an ambrette
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: not used anymore
Synonyms   Articles   Notes   Search   Top
Suppliers:
Anhui Haibei
Musk Ambrette
Odor: Musty sweet ambrette seed
Associate Allied Chemicals
Musk Ambrette
About
BOC Sciences
For experimental / research use only.
Musk Ambrette
Fleurchem
musk ambrette
Fuzhou Farwell
Musk Ambrette
Indenta Group
Musk Ambrette
Jiangyin Healthway
Musk Ambrette
New functional food ingredients
K.L. Koh Enterprise
MUSK AMBRETTE
Lluch Essence
MUSK AMBRETTE
M&U International
Musk Ambrette
Pearlchem Corporation
Musk Ambrette
Penta International
MUSK AMBRETTE
Perfumer Supply House
Musk Ambrette
Odor: Sweet musk, floral, seedy, ambrette note
Perfumery Laboratory
MUSKUS AMBRETTES crystals (Musk Ambrette)
Odor: Sweet, musky, floral, with a pear shade and a bright note of an ambrette
Reincke & Fichtner
Musk Ambrette
SRS Aromatics
MUSK AMBRETTE
Sunaux International
Musk Ambrette
TCI AMERICA
For experimental / research use only.
4-tert-Butyl-3-methoxy-2,6-dinitrotoluene >99.0%(GC)
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  339 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.

Dermal Toxicity:
skin-rabbit LD50 > 2000 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 875, 1975.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: information only not used for fragrances or flavors
IFRA Critical Effect: Photosensitization and neurotoxicity
IFRA: View Standard
Recommendation for musk ambrette usage levels up to:
 PROHIBITED: Should not be used as a fragrance ingredient.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3. Update in publication number(s): 13
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -0.41000
beverages(nonalcoholic): -0.43000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -9.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -0.26000
fruit ices: -0.26000
gelatins / puddings: -0.01000
granulated sugar: --
gravies: --
hard candy: -4.80000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 83-66-9
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 6753
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 1-tert-butyl-2-methoxy-4-methyl-3,5-dinitrobenzene
Chemidplus: 0000083669
EPA/NOAA CAMEO: hazardous materials
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References:
 1-tert-butyl-2-methoxy-4-methyl-3,5-dinitrobenzene
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 83-66-9
Pubchem (cid): 6753
Pubchem (sid): 134971693
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C19461
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2909.50.5000
ChemSpider: View
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Potential Blenders and core components note
 
For Odor
No odor group found for these
 atractylis absoluteFR
amber
 ambrette seed oilFL/FR
 cistus ladaniferus resinoidFL/FR
animal
 civet absoluteFL/FR
balsamic
 abies alba needle oilFL/FR
 copaiba balsam oilFL/FR
 fir needle oil siberiaFL/FR
 tolu balsamFL/FR
floral
isoamyl salicylateFL/FR
isobutyl salicylateFL/FR
herbal
 acorus calamus root oilFR
 clary sage oil franceFL/FR
 lavender absolute bulgariaFL/FR
spicy
 cinnamyl acetateFL/FR
 turmeric root oil chinaFL/FR
tonka
 coumarinFR
 deertongue absoluteFR
woody
 cedarwood oil virginiaFR
2-decalinyl formateFR
isolongifolene epoxideFR
 patchouli oilFL/FR
 vetiverolFL/FR
 
For Flavor
 
No flavor group found for these
 cistus ladaniferus resinoidFL/FR
amber
 ambrette seed oilFL/FR
animal
 civet absoluteFL/FR
balsamic
 copaiba balsam oilFL/FR
 fir needle oil siberiaFL/FR
 tolu balsamFL/FR
cooling
isobutyl salicylateFL/FR
green
isoamyl salicylateFL/FR
herbal
 clary sage oil franceFL/FR
 lavender absolute bulgariaFL/FR
orris
 costus root oilFL
spicy
 cinnamyl acetateFL/FR
 turmeric root oil chinaFL/FR
terpenic
 abies alba needle oilFL/FR
woody
 patchouli oilFL/FR
 vetiverolFL/FR
 
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Potential Uses:
 amberFR
 ambergrisFR
 castoreumFR
 civetFR
 mossFR
 muskFR
 orientalFR
 roseFR
 tobaccoFR
 woodyFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 not found in nature
Synonyms   Articles   Notes   Search   Top
Synonyms:
 amber musk
 ambrette musk
 anisole, 6-t-butyl-3-methyl-2,4-dinitro-
 anisole, 6-tert-butyl-3-methyl-2,4-dinitro-
 benzene, 1- (1,1-dimethylethyl)-2-methoxy-4-methyl-3,5-dinitro-
 benzene, 1-(1,1-dimethylethyl)-2-methoxy-4-methyl-3,5-dinitro-
5-tert-butyl-1,3-dinitro-4-methoxy-2-methylbenzene
1-tert-butyl-2-methoxy-4-methyl-3,5-dinitro-benzene
1-tert-butyl-2-methoxy-4-methyl-3,5-dinitrobenzene
1-tert-butyl-2-methoxy-4-methyl-3,5-dinitrobenzol
4-tert-butyl-2,6-dinitro-3-methoxytoluene
4-tert-butyl-3-methoxy-1-methyl-2,6-dinitrobenzene
4-tert-butyl-3-methoxy-2,6-dinitrotoluene
6-tert-butyl-3-methyl-2,4-dinitroanisol
6-tert-butyl-3-methyl-2,4-dinitroanisole
6-tert-butyl-3-methyl-2,4-dinitrophenyl methyl ether
1-(tert-butyl)-2-methoxy-4-methyl-3,5-dinitrobenzene
1-(1,1-dimethyl ethyl)-2-methoxy-4-methyl-3,5-dinitrobenzene
1-(1,1-dimethylethyl)-2-methoxy-4-methyl-3,5-dinitrobenzene
2,6-dinitro-3-methoxy-1-methyl-4-tert-butyl benzene
2,6-dinitro-3-methoxy-1-methyl-4-tert-butylbenzene
2,6-dinitro-3-methoxy-4-tert-butyltoluene
2,4-dinitro-3-methyl-6-tert-butyl anisole
2,4-dinitro-3-methyl-6-tert-butylanisole
 griselimycine
4-methoxy-1,3-dinitro-2-methyl-5-tert-butyl benzene
4-methoxy-1,3-dinitro-2-methyl-5-tert-butylbenzene
2-methoxy-4-methyl-1-(2-methyl-2-propanyl)-3,5-dinitrobenzene
 musk ambrette
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Articles:
Info: MUSK
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