Category: cosmetic, flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Organoleptic Properties:
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Odor Type: minty |
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Odor Strength: | medium , recommend smelling in a 10.00 % solution or less |
|
Substantivity: | 8 hour(s) at 100.00 % |
|
| wintergreen minty |
Odor Description: at 10.00 % in dipropylene glycol. | wintergreen mint Luebke, William tgsc, (1983) |
|
| sweet root beer wintergreen aromatic phenolic camphoreous |
Odor Description:
| Sweet, salicylate, root beer, wintergreen, aromatic, slightly phenolic and camphoreous Mosciano, Gerard P&F 20, No. 6, 49, (1995) |
|
|
Flavor Type: minty |
|
| sweet wintergreen root beer aromatic balsamic |
Taste Description: at 10.00 ppm. | Sweet, salicylate and root beer with aromatic and balsamic nuances Mosciano, Gerard P&F 20, No. 6, 49, (1995) |
|
Odor and/or flavor descriptions from others (if found). |
|
Sigma-Aldrich |
Methyl salicylate, ≥98%, FCC, FG |
Odor Description: | minty; spicy; sweet |
|
Moellhausen |
METHYL SALICYLATE |
Odor Description: | aromatic, sweet, curative, phenolic |
Taste Description: | sweet, wintergreen |
|
PerfumersWorld |
Methyl Salicylate |
Odor Description: | medicinal wintergreen warm-spicy sweet fruity grape rooty-fruity Blends-well-with - +Pennyroyal +Orange Oil +Patchouli Gums |
|
Pell Wall Perfumes |
Methyl Salicylate |
Odor Description: | Warm, sweet, rooty-fruity medicinal, salicylate, wintergreen, tuberose Here is Arctander on the odour: “Pungent-sweet, fruity-rooty odor with bur- ning sensation at high concentration. As a result of the subconscious reaction in people who are regular users of candy, flavored with Methylsalicylate, or dentifrice etc., the comment “minty” is often used for description of the flavor or odor of this ester. The most reliable judges for odor description are those who are not users of the item as a flavor. |
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Cosmetic Information:
Suppliers:
Achiewell |
For experimental / research use only. |
Methyl Salicylate
|
Acme-Hardesty |
Methyl Salicylate
Odor: characteristic Use: Emulsifier for Lubes and Greases. Used in Mouthwash, and as an Active Ingredient in Sports Rubs. |
Advanced Biotech |
METHYL SALICYLATE NATURAL
99% min. |
Advanced Biotech |
METHYL SALICYLATE SYNTHETIC
99% min. |
Alfa Biotechnology |
For experimental / research use only. |
Methyl salicylate 98%
|
Ambles Nature et Chimie |
SALICYLATE DE METHYLE NAT
|
Augustus Oils |
Methyl Salicylate
|
Services |
Aurochemicals |
METHYL SALICYLATE, Natural
|
Axxence Aromatic |
METHYL SALICYLATE Natural
Kosher |
Sustainability |
Beijing Lys Chemicals |
Methyl Salicylate
|
Bell Flavors & Fragrances |
Methyl Salicylate
|
Berjé |
Methyl Salicylate
|
Media |
BOC Sciences |
For experimental / research use only. |
Methyl Salicylate >98%
|
Charkit Chemical |
METHYL SALICYLATE USP NF, FCC
|
Charkit Chemical |
METHYL SALICYLATE USP
|
Charkit Chemical |
METHYL SALICYLATE
|
Citrus and Allied Essences |
Methyl Salicylate 98% (natural)
|
Market Report |
Citrus and Allied Essences |
Methyl Salicylate FCC
|
Creatingperfume.com |
Methyl Salicylate
Odor: medicinal wintergreen warm-spicy sweet fruity grape |
De Monchy Aromatics |
Methyl Salicylate
|
ECSA Chemicals |
METHYL SALICYLATE FLAVOUR USE
|
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
ECSA Chemicals |
METHYL SALICYLATE
|
Ernesto Ventós |
METHYL SALICYLATE EXTRA
|
Ernesto Ventós |
METHYL SALICYLATE
Odor: MEDICINE, SWEET, PHENOLYC |
Excellentia International |
Methyl Salicylate Natural
|
Excellentia International |
Methyl Salicylate NF/FCC
|
ExtraSynthese |
For experimental / research use only. |
Salicylic acid methylester (GC) ≥95%
|
Fleurchem |
methyl salicylate natural
|
Fleurchem |
methyl salicylate
|
Foodchem International |
Methyl Salicylate
|
Foreverest Resources |
Methyl Salicylate 99%
Odor: characteristic Use: Methyl salicylate is extracted from essential oil of Wintergereen oil, Ylang ylang oil and Acacia oil. Has wintergreen character floral and fruity. It applied as fragrance ingredient on toothpaste, also using in food ingredient limited in 8400mg/kg, the value of ADI is 0.5mg/kg. |
Frey + Lau |
Methyl Salicylate Ph. Eur.
Odor: Similar to wintergreen, dominant, slightly medical |
Fuzhou Farwell |
Methyl Salicylate
|
George Uhe Company |
Methyl Salicylate
|
Global Essence |
Methyl Salicylate 100
|
Global Essence |
Methyl Salicylate 20
|
Global Essence |
Methyl Salicylate 25
|
Global Essence |
Methyl Salicylate 50
|
Global Essence |
Methyl Salicylate NF
|
Graham Chemical |
Methyl Salicylate Natural (Wintergreen Oil)
|
Graham Chemical |
Methyl Salicylate Synthetic
|
Indenta Group |
Methyl Salicylate
|
Indukern F&F |
METHYL SALICYLATE
Odor: MEDICINAL, PHENOLIC, AROMATIC, SWEET |
John Kellys (London) |
Methyl Salicylate
|
K.L. Koh Enterprise |
METHYL SALICYLATE
|
Keva |
METHYL SALICYLATE
|
Kraft Chemical |
Methyl Salicylate
|
Lluch Essence |
METHYL SALICYLATE NATURAL
|
Lluch Essence |
METHYL SALICYLATE
|
M&U International |
Methyl Salicylate, Kosher
|
Moellhausen |
METHYL SALICYLATE
Odor: aromatic, sweet, curative, phenolic Flavor: sweet, wintergreen |
Northwestern Extract |
Methyl Salicylate USP
|
OQEMA |
Methyl Salicylate
|
Pearlchem Corporation |
Methyl Salicylate
|
Pell Wall Perfumes |
Methyl Salicylate
Odor: Warm, sweet, rooty-fruity medicinal, salicylate, wintergreen, tuberose Use: Here is Arctander on the odour: “Pungent-sweet, fruity-rooty odor with bur- ning sensation at high concentration. As a result of the subconscious reaction in people who are regular users of candy, flavored with Methylsalicylate, or dentifrice etc., the comment “minty” is often used for description of the flavor or odor of this ester. The most reliable judges for odor description are those who are not users of the item as a flavor. |
Penta International |
METHYL SALICYLATE FCC
|
Penta International |
METHYL SALICYLATE NATURAL
|
Penta International |
METHYL SALICYLATE NF - USP GRADE
|
Penta International |
METHYL SALICYLATE NF/FCC GRADE
|
Penta International |
METHYL SALICYLATE TECHNICAL GRADE
|
Penta International |
METHYL SALICYLATE
|
PerfumersWorld |
Methyl Salicylate
Odor: medicinal wintergreen warm-spicy sweet fruity grape rooty-fruity Use: Blends-well-with - +Pennyroyal +Orange Oil +Patchouli Gums |
Perfumery Laboratory |
Methyl Salicylate
Odor: Sweet mint, fruit and grapes, balsamic aroma with a hint of wintergreen |
Phoenix Aromas & Essential Oils |
Methyl Salicylate
|
Prinova |
Methyl Salicylate
|
Prodasynth |
METHYL SALICYLATE
(> 99%) Odor: MEDICINE, SWEET, PHENOLYC |
R C Treatt & Co Ltd |
Methyl Salicylate
|
Reincke & Fichtner |
Methyl Salicylate natural
|
Reincke & Fichtner |
Methyl Salicylate
|
Robertet |
METHYL SALICYLATE (METHYL 2-HYDROXYBENZOATE)
Pure & Nat (EU) |
Seasons and Harvest / Crop calendar |
Sigma-Aldrich |
Methyl salicylate, ≥98%, FCC, FG
Odor: minty; spicy; sweet |
Certified Food Grade Products |
Sigma-Aldrich |
Methyl salicylate, natural, 98%, FCC, FG
|
SRS Aromatics |
METHYL SALICYLATE
|
Sunaux International |
Methyl Salicylate
|
SysKem Chemie |
Methyl Salicylate
|
TCI AMERICA |
For experimental / research use only. |
Methyl Salicylate >99.0%(GC)
|
The John D. Walsh Company |
Methyl Salicylate
|
The Lermond Company |
METHYL SALICYLATE, USP
|
The Perfumers Apprentice |
Methyl Salicylate
Odor: Sweet, wintergreen, aromatic |
Ungerer & Company |
Methyl Salicylate <150 PPM
|
Ungerer & Company |
Methyl Salicylate Fractions
|
Ungerer & Company |
Methyl Salicylate Low Phenol
|
Ungerer & Company |
Methyl Salicylate Natural
|
United International |
Methyl Salicylate
|
Vigon International |
Methyl Salicylate Extra Pure (Phenol less than 50 ppm)
|
Vigon International |
Methyl Salicylate Natural
|
Vigon International |
Methyl Salicylate
|
WEN International |
METHYL SALICYLATE Natural
|
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xn - Harmful. |
R 22 - Harmful if swallowed. R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection.
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Hazards identification |
|
Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
Acute toxicity, Oral (Category 4), H302 Acute aquatic toxicity (Category 3), H402
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GHS Label elements, including precautionary statements |
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Pictogram | |
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Signal word | Warning |
Hazard statement(s) |
H302 - Harmful if swallowed H402 - Harmful to aquatic life
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Precautionary statement(s) |
P264 - Wash skin thouroughly after handling. P270 - Do not eat, drink or smoke when using this product. P273 - Avoid release to the environment. P301 + P312 - IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P330 - Rinse mouth. P501 - Dispose of contents/ container to an approved waste disposal plant.
|
Human Experience: |
8 % solution: no irritation or sensitization. |
Oral/Parenteral Toxicity: |
gavage-mouse LD50 [sex: M] 1390 mg/kg (Ohsumi et al., 1984)
gavage-rat LD50 1250 mg/kg (Giroux et al., 1954b)
oral-rat LD50 [sex: M,F] M:3049.00 F:2642 mg/kg (Givaudan Corporation, 1982)
gavage-rat LD50 [sex: M,F] 887 mg/kg (Jenner et al., 1964)
oral-rat LD50 1220 mg/kg (Nivikov et al., 1994)
oral-mouse LD50 [sex: M] 1110 mg/kg (Davison et al., 1961)
gavage-guinea pig LD50 [sex: M,F] 1060 mg/kg (Jenner et al., 1964)
gavage-mouse LD50 [sex: M,F] 1440 mg/kg (NTP, 1984a)
oral-woman LDLo 355 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
GASTROINTESTINAL: NAUSEA OR VOMITING
BEHAVIORAL: COMA American Journal of the Medical Sciences. Vol. 193, Pg. 772, 1937.
oral-rat LD50 887 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.
oral-rabbit LD50 1300 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 821, 1978.
oral-mouse LD50 1110 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 132, Pg. 207, 1961.
unreported-man LDLo 522 mg/kg "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
oral-man LDLo 1329 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: COMA
BLOOD: HEMORRHAGE Clinical Toxicology. Vol. 6, Pg. 189, 1973.
oral-man LDLo 101 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
GASTROINTESTINAL: NAUSEA OR VOMITING American Journal of the Medical Sciences. Vol. 193, Pg. 772, 1937.
oral-human LDLo 506 mg/kg "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 961, 1989.
oral-guinea pig LD50 700 mg/kg "Industrial Hygiene and Toxicology," 2nd ed., Patty, F.A., ed., New York, John Wiley & Sons, Inc., 1958-63Vol. 2, Pg. 1897, 1963.
oral-dog LD50 2100 mg/kg GASTROINTESTINAL: NAUSEA OR VOMITING
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Food and Cosmetics Toxicology. Vol. 16, Pg. 821, 1978.
oral-child LDLo 700 mg/kg BEHAVIORAL: GENERAL ANESTHETIC
PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA Archives of Disease in Childhood. Vol. 28, Pg. 475, 1953.
oral-child LDLo 228 mg/kg GASTROINTESTINAL: NAUSEA OR VOMITING
LUNGS, THORAX, OR RESPIRATION: DYSPNEA American Journal of Diseases of Children. Vol. 69, Pg. 37, 1945.
|
Dermal Toxicity: |
subcutaneous-dog LDLo 2250 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 821, 1978.
subcutaneous-guinea pig LDLo 1500 mg/kg FAO Nutrition Meetings Report Series. Vol. 44A, Pg. 63, 1967.
subcutaneous-rabbit LDLo 4250 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 821, 1978.
|
Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | cosmetic, flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
maximum skin levels for fine fragrances: | | 0.2900 % and are based on the assumption that the fragrance mixture is used at 20% in a consumer product (IFRA Use Level Survey). (IFRA, 2002)
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Recommendation for methyl salicylate usage levels up to: | | 10.0000 % in the fragrance concentrate.
|
use level in formulae for use in cosmetics: | | 0.1300 %
|
Dermal Systemic Exposure in Cosmetic Products: | | 0.0034 mg/kg/day (IFRA, 2002)
|
|
Maximised Survey-derived Daily Intakes (MSDI-EU): | 410.00 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 44000.00 (μg/capita/day) |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | - | 54.00000 |
beverages(nonalcoholic): | - | 59.00000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | 8400.00000 |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 27.00000 |
fruit ices: | - | 27.00000 |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 840.00000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s): |
The FEMA GRAS assessment of hydroxyl- and alkoxy-substituted benzyl derivatives used as flavor ingredients. View pdf |
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23 View page or View pdf |
Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 54 (FGE.54)[1] - Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20 (2005) - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf |
Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23 View page or View pdf |
Flavouring Group Evaluation 54, Revision 1 (FGE.54Rev1): Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20Rev1 (2009) View page or View pdf |
Scientific Report of EFSA on the risk assessment of salts of authorised acids, phenols or alcohols for use in food contact materials [1] View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
EPI System: | View |
ClinicalTrials.gov: | search |
Daily Med: | search |
NIOSH International Chemical Safety Cards: | search |
Chemical Carcinogenesis Research Information System: | Search |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 119-36-8 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 4133 |
National Institute of Allergy and Infectious Diseases: | Data |
WISER: | UN 3082 |
WGK Germany: | 1 |
| methyl 2-hydroxybenzoate |
Chemidplus: | 0000119368 |
EPA/NOAA CAMEO: | hazardous materials |
RTECS: | 119-36-8 |
References:
Other Information:
(IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
Videos: | The Periodic Table of Videos |
tgsc: | Atomic Weights use for this web site |
(IUPAC): | Periodic Table of the Elements |
FDA Substances Added to Food (formerly EAFUS): | View |
FDA Indirect Additives used in Food Contact Substances: | View |
CHEBI: | View |
CHEMBL: | View |
KEGG (GenomeNet): | C12305 |
HMDB (The Human Metabolome Database): | HMDB34172 |
FooDB: | FDB012459 |
YMDB (Yeast Metabolome Database): | YMDB01370 |
Export Tariff Code: | 2918.23.0000 |
Typical G.C. |
VCF-Online: | VCF Volatile Compounds in Food |
ChemSpider: | View |
Wikipedia: | View |
Formulations/Preparations: •usp: liniment, compound: menthol 4.5 g, camphor oil rectified 25 ml, olive or peanut oil 30 ml, methyl salicylate to make 100 ml. ointment, compound: methyl salicylate 10 ml, menthol 10 g, white wax 5 g, hydrous wool fat to make 100 g.
•usp: spirit, phenolated (podiatry): liquefied phenol 1 ml, methyl salicylate 3 ml, compound myrcia spirit 25 ml, alcohol rubbing compound to make 100 ml.
•grades: technical; usp; fcc.
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Potential Blenders and core components note
|
For Odor |
No odor group found for these |
|
| camel grass oil | FR |
| cyclopentanone | FL/FR |
| eucarvone | |
| lippia alnifolia schau. leaf oil brazil | |
laevo-mono | menthyl glutarate | FL/FR |
laevo- | menthyl methyl ether | FL/FR |
| pinocarvone | FL/FR |
| satureja viminea oil costa rica | |
| umbellulone | |
aldehydic |
iso | butyraldehyde | FL/FR |
| dodecanal (aldehyde C-12 lauric) | FL/FR |
animal |
para- | cresyl phenyl acetate | FL/FR |
anisic |
para- | anisaldehyde | FL/FR |
| dihydroanethol | FL/FR |
| estragole | FL/FR |
balsamic |
iso | amyl benzoate | FL/FR |
| benzyl salicylate | FL/FR |
laevo- | bornyl acetate | FL/FR |
iso | bornyl acetate | FL/FR |
iso | bornyl formate | FL/FR |
| cinnamyl alcohol | FL/FR |
| guaiacyl phenyl acetate | FL/FR |
| methyl cinnamate | FL/FR |
| nonyl benzoate | |
| opoponax absolute (balsamodendron kafal) | FL/FR |
3- | phenyl propyl alcohol | FL/FR |
berry |
| raspberry ketone methyl ether | FL/FR |
camphoreous |
dextro- | camphor | FL/FR |
| camphor tree bark oil | FL/FR |
| herbal ethanone | FR |
| thujyl alcohol | FL/FR |
caramellic |
| ethyl maltol | FL/FR |
citrus |
| ocimene quintoxide | FL/FR |
sweet | orange peel oil c.p. brazil | FL/FR |
earthy |
3- | octanol | FL/FR |
| patchouli cyclohexanol | FR |
fatty |
| decanol | FL/FR |
floral |
alpha- | amyl cinnamaldehyde | FL/FR |
iso | amyl salicylate | FL/FR |
| amyl salicylate | FL/FR |
| benzyl acetate | FL/FR |
| bois de rose oil brazil | FL/FR |
iso | butyl salicylate | FL/FR |
| citronellal diisotridecyl acetal | FR |
| coriander seed oil | FL/FR |
| cyclamen aldehyde | FL/FR |
| cyclohexyl ethyl acetate | FL/FR |
| cyclohexyl propanol | FR |
2- | decalinol | FR |
| dihydrocarvyl acetate | FL/FR |
2',4'- | dimethyl acetophenone | FL/FR |
| earthy indane | FR |
| floral methanol | FR |
| geraniol | FL/FR |
| geranium oil china | FL/FR |
| heliotropin | FL/FR |
(Z)-3- | hexen-1-yl salicylate | FL/FR |
alpha- | hexyl cinnamaldehyde | FL/FR |
| ho leaf oil | FR |
| hydroxycitronellal | FL/FR |
| linalool | FL/FR |
laevo- | linalool | FL/FR |
| linalool oxide | FL/FR |
| menthadienyl formate | FR |
| muguet butanol | FR |
| ocean propanal | FL/FR |
| phenethyl acetate | FL/FR |
| phenethyl salicylate | FL/FR |
| rose butanoate | FL/FR |
| tetrahydrolinalool | FL/FR |
| ylang ylang flower oil III | FL/FR |
fruity |
| benzyl propionate | FL/FR |
3- | benzyl-4-heptanone | FL/FR |
2- | cyclopentyl cyclopentanone | FL/FR |
gamma- | decalactone | FL/FR |
| diethyl malonate | FL/FR |
| ethyl heptanoate | FL/FR |
| green acetate | FR |
| lilac lactone | FL/FR |
gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
green |
| geranium absolute | FL/FR |
(Z)-3- | hexen-1-yl acetate | FL/FR |
(Z)- | leaf acetal | FL/FR |
| thiogeraniol | FL/FR |
| artemisyl ketone | FL/FR |
| barosma betulina leaf oil | FL/FR |
| carum carvi fruit oil | FL/FR |
1,4- | cineole | FL/FR |
| costmary oil (chrysanthemum balsamita) | FR |
2- | cyclohexyl cyclohexanone | FR |
| dehydroxylinalool oxide | FL/FR |
iso | dihydrolavandulol | FR |
(Z)-iso | dihydrolavandulyl acetate | FR |
2,10- | epoxypinane | FR |
| herbal undecanol | FR |
| hyssop oil | FL/FR |
| linalyl acetate | FL/FR |
para- | menthane-3,8-diol | FL/FR |
| myrtenol | FL/FR |
| nopyl acetate | FR |
3- | octyl acetate | FL/FR |
laevo- | perillaldehyde | FL/FR |
| perillaldehyde | FL/FR |
| pine hexanol | FR |
D-(+)-alpha- | pinene | FL/FR |
| piperitone | FL/FR |
| rosemary absolute | FL/FR |
| rosemary oil morocco | FL/FR |
| sabinene hydrate | FL/FR |
common | tansy flower oil | FR |
common | tansy flower oil dutch | FR |
| viridiflorol | FL/FR |
licorice |
sweet | basil oleoresin | FL/FR |
mentholic |
| cornmint oil | FL/FR |
| cornmint oil india | FL/FR |
| cornmint oil terpeneless | FL/FR |
(±)- | menthol | FL/FR |
laevo- | menthol | FL/FR |
dextro,laevo- | menthol | FL/FR |
dextro-neo | menthol | FL/FR |
(±)-iso | menthone | FL/FR |
laevo- | menthyl acetate | FL/FR |
| menthyl acetate | FL/FR |
| menthyl acetate racemic | FL/FR |
| peppermint cyclohexanone | FL/FR |
dextro- | piperitone | FL/FR |
iso | pulegyl acetate | FL/FR |
minty |
| agathosma crenulata leaf oil | FL/FR |
| betula lenta bark oil america | FL/FR |
| camphene hydrate | |
laevo- | carveol | FL/FR |
laevo- | carvone | FL/FR |
| carvone | FL/FR |
cis- | carvone-5,6-oxide | FL/FR |
| carvyl propionate | FL/FR |
| cyclohexanone | FR |
| dihydrocarveol | FL/FR |
| diosphenol | FL/FR |
| ethyl benzoate | FL/FR |
| ethyl salicylate | FL/FR |
bitter | fennel seed oil | FR |
| gaultheria procumbens leaf extract | FL/FR |
| mentha longifolia oil | FR |
dextro-2,8-para- | menthadien-1-ol | FL/FR |
trans-para-2,8-1- | menthadienol | FL/FR |
trans-para- | menthan-2-one | FL/FR |
homo | menthol | FL/FR |
(-)- | menthone | FL/FR |
| menthoxypropane diol | FL/FR |
homo | menthyl acetate | FL/FR |
2- | methyl cyclohexanone | FL/FR |
| pennyroyal oil | FL/FR |
| pennyroyal oil cuba | FL/FR |
| pennyroyal oil spain | FL/FR |
| pennyroyal oil uruguay | FL/FR |
| peppermint oil CO2 extract | FL/FR |
| peppermint oil idaho | FL/FR |
| peppermint oil mongolia | FL/FR |
| peppermint oil russia | FL/FR |
| peppermint oil terpeneless | FL/FR |
beta- | phellandrene | FL/FR |
| piperitenone | FL/FR |
laevo- | piperitone | FL/FR |
iso | propyl tiglate | FL/FR |
(-)-iso | pulegol | FL/FR |
(R)-(+)- | pulegone | FR |
iso | pulegone | FL/FR |
iso | pulegyl formate | FL/FR |
| spearmint absolute | FL/FR |
| spearmint oil america | FL/FR |
| spearmint oil terpeneless | FL/FR |
| tetrahydrocarvone | FL/FR |
| vanillin menthoxypropane diol acetal | FL/FR |
| wintergreen oil | FL/FR |
| WS-23 | FL/FR |
naphthyl |
ortho- | methyl anisole | FL/FR |
pine |
| plectranthus glandulosus hook f. leaf oil cameroon | FR |
smoky |
2,6- | dimethoxyphenol | FL/FR |
spicy |
| benzyl isoeugenol | FL/FR |
| carvacrol | FL/FR |
| cassia bark oil china | FL/FR |
| cinnamon bark oil ceylon | FL/FR |
| clove bud oil | FL/FR |
| clove bud oleoresin | FL/FR |
N,N- | diethyl octanamide | FR |
| eugenol | FL/FR |
alpha- | methyl cinnamaldehyde | FL/FR |
| pimenta acris leaf oil | FL/FR |
laevo- | verbenone | FL/FR |
sulfurous |
| buchu mercaptan | FL/FR |
| grapefruit menthane | FL/FR |
terpenic |
alpha- | terpineol | FL/FR |
thujonic |
| armoise oil | FR |
common | tansy oil canada | FR |
tonka |
| coumarin | FR |
tropical |
beta- | cyclocitral | FL/FR |
vanilla |
| ethyl vanillin | FL/FR |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
| vanillyl acetate | FL/FR |
waxy |
1- | dodecanol | FL/FR |
woody |
para-tert- | butyl cyclohexanone | FR |
| gurjun balsam oil | FR |
| patchouli ethanol | FR |
| patchouli ethanone | FR |
| patchouli hexanol | FR |
cis-2- | pinanol | FR |
| santall | FR |
(Z)- | woody amylene | FR |
|
For Flavor |
|
No flavor group found for these |
| artemisyl ketone | FL/FR |
| camphene hydrate | |
| carvone | FL/FR |
| cyclopentanone | FL/FR |
2- | cyclopentyl cyclopentanone | FL/FR |
2',4'- | dimethyl acetophenone | FL/FR |
(±)-N,N- | dimethyl menthyl succinamide | FL |
| eucarvone | |
| lilac lactone | FL/FR |
| limonen-10-yl acetate | FL |
| lippia alnifolia schau. leaf oil brazil | |
dextro-2,8-para- | menthadien-1-ol | FL/FR |
cis+trans-para-1(7)8- | menthadien-2-yl acetate | FL |
trans-para-2,8-1- | menthadienol | FL/FR |
para- | menthane-3,8-diol | FL/FR |
3-laevo- | menthoxy-2-methyl propane-1,2-diol | FL |
| menthoxypropane diol | FL/FR |
| menthyl acetate racemic | FL/FR |
laevo-mono | menthyl glutarate | FL/FR |
laevo- | menthyl methyl ether | FL/FR |
| menthyl propylene glycol carbonate | FL |
2- | methyl cyclohexanone | FL/FR |
| nonyl benzoate | |
beta- | phellandrene | FL/FR |
(Z,Z)- | photocitral A | FL |
D-(+)-alpha- | pinene | FL/FR |
| pinocarvone | FL/FR |
| piperitenone | FL/FR |
| piperitenone oxide | FL |
iso | pulegone | FL/FR |
iso | pulegyl formate | FL/FR |
| satureja viminea oil costa rica | |
| umbellulone | |
| vanillin menthoxypropane diol acetal | FL/FR |
laevo- | verbenone | FL/FR |
| viridiflorol | FL/FR |
|
| menthyl methyl lactate | FL |
| thujyl alcohol | FL/FR |
aldehydic |
iso | butyraldehyde | FL/FR |
alliaceous |
| benzyl mercaptan | FL |
aromatic |
| amyl salicylate | FL/FR |
laevo- | perillaldehyde | FL/FR |
balsamic |
| benzyl salicylate | FL/FR |
laevo- | bornyl acetate | FL/FR |
| opoponax absolute (balsamodendron kafal) | FL/FR |
berry |
| raspberry ketone methyl ether | FL/FR |
camphoreous |
| camphor tree bark oil | FL/FR |
ortho- | methyl anisole | FL/FR |
caramellic |
| ethyl maltol | FL/FR |
cherry |
| heliotropin | FL/FR |
citrus |
laevo- | linalool | FL/FR |
| linalool | FL/FR |
sweet | orange peel oil c.p. brazil | FL/FR |
alpha- | terpineol | FL/FR |
coffee |
2-iso | propyl pyrazine | FL |
cooling |
iso | butyl salicylate | FL/FR |
1,4- | cineole | FL/FR |
laevo- | menthol | FL/FR |
dextro,laevo- | menthol | FL/FR |
homo | menthyl acetate | FL/FR |
| menthyl acetate | FL/FR |
| sabinene hydrate | FL/FR |
| WS-5 | FL |
creamy |
para- | anisaldehyde | FL/FR |
gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
floral |
| bois de rose oil brazil | FL/FR |
| dihydrocarvyl acetate | FL/FR |
| geraniol | FL/FR |
| geranium oil china | FL/FR |
| linalyl acetate | FL/FR |
| ocean propanal | FL/FR |
| tetrahydrolinalool | FL/FR |
| ylang ylang flower oil III | FL/FR |
fruity |
iso | amyl benzoate | FL/FR |
| benzyl acetate | FL/FR |
| benzyl propionate | FL/FR |
3- | benzyl-4-heptanone | FL/FR |
gamma- | decalactone | FL/FR |
| diethyl malonate | FL/FR |
| ethyl heptanoate | FL/FR |
| rose butanoate | FL/FR |
green |
iso | amyl salicylate | FL/FR |
| cinnamyl alcohol | FL/FR |
| cyclamen aldehyde | FL/FR |
| cyclohexyl ethyl acetate | FL/FR |
| dihydrocarveol | FL/FR |
| geranium absolute | FL/FR |
(Z)-3- | hexen-1-yl acetate | FL/FR |
(Z)-3- | hexen-1-yl salicylate | FL/FR |
(Z)- | leaf acetal | FL/FR |
| linalool oxide | FL/FR |
| ocimene quintoxide | FL/FR |
3- | octyl acetate | FL/FR |
iso | propyl tiglate | FL/FR |
| thiogeraniol | FL/FR |
herbal |
2- | acetoxy-1,8-cineole | FL |
| barosma betulina leaf oil | FL/FR |
| carum carvi fruit oil | FL/FR |
| coriander seed oil | FL/FR |
| dihydroanethol | FL/FR |
| hyssop oil | FL/FR |
| rosemary absolute | FL/FR |
| rosemary oil morocco | FL/FR |
honey |
| phenethyl acetate | FL/FR |
licorice |
sweet | basil oleoresin | FL/FR |
| estragole | FL/FR |
meaty |
2- | methyl 3-(methyl thio) furan | FL |
medicinal |
dextro- | camphor | FL/FR |
2,6- | dimethoxyphenol | FL/FR |
| ethyl benzoate | FL/FR |
| phenethyl salicylate | FL/FR |
mentholic |
| cornmint oil | FL/FR |
| cornmint oil terpeneless | FL/FR |
dextro-neo | menthol | FL/FR |
(±)- | menthol | FL/FR |
| peppermint cyclohexanone | FL/FR |
minty |
| agathosma crenulata leaf oil | FL/FR |
| betula lenta bark oil america | FL/FR |
laevo- | carveol | FL/FR |
laevo- | carvone | FL/FR |
cis- | carvone-5,6-oxide | FL/FR |
| carvyl propionate | FL/FR |
| cornmint oil india | FL/FR |
| diosphenol | FL/FR |
| ethyl salicylate | FL/FR |
| gaultheria procumbens leaf extract | FL/FR |
trans-para- | menthan-2-one | FL/FR |
homo | menthol | FL/FR |
(-)- | menthone | FL/FR |
(±)-iso | menthone | FL/FR |
laevo- | menthyl acetate | FL/FR |
| myrtenol | FL/FR |
| pennyroyal oil | FL/FR |
| pennyroyal oil cuba | FL/FR |
| pennyroyal oil spain | FL/FR |
| pennyroyal oil uruguay | FL/FR |
| peppermint oil CO2 extract | FL/FR |
| peppermint oil idaho | FL/FR |
| peppermint oil mongolia | FL/FR |
| peppermint oil russia | FL/FR |
| peppermint oil terpeneless | FL/FR |
| piperitone | FL/FR |
dextro- | piperitone | FL/FR |
laevo- | piperitone | FL/FR |
(-)-iso | pulegol | FL/FR |
| spearmint absolute | FL/FR |
| spearmint oil america | FL/FR |
| spearmint oil terpeneless | FL/FR |
| teaberry flavor | FL |
| tetrahydrocarvone | FL/FR |
| wintergreen flavor | FL |
| wintergreen oil | FL/FR |
| WS-23 | FL/FR |
musty |
3- | octanol | FL/FR |
phenolic |
para- | cresyl phenyl acetate | FL/FR |
| guaiacyl phenyl acetate | FL/FR |
soapy |
| dodecanal (aldehyde C-12 lauric) | FL/FR |
1- | dodecanol | FL/FR |
spicy |
| benzyl isoeugenol | FL/FR |
| carvacrol | FL/FR |
| cassia bark oil china | FL/FR |
| cinnamon bark oil ceylon | FL/FR |
| clove bud oil | FL/FR |
| clove bud oleoresin | FL/FR |
| eugenol | FL/FR |
4- | methyl biphenyl | FL |
alpha- | methyl cinnamaldehyde | FL/FR |
| methyl cinnamate | FL/FR |
| perillaldehyde | FL/FR |
3- | phenyl propyl alcohol | FL/FR |
| pimenta acris leaf oil | FL/FR |
sulfurous |
| buchu mercaptan | FL/FR |
| grapefruit menthane | FL/FR |
tropical |
alpha- | amyl cinnamaldehyde | FL/FR |
beta- | cyclocitral | FL/FR |
vanilla |
| ethyl vanillin | FL/FR |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
| vanillyl acetate | FL/FR |
waxy |
| decanol | FL/FR |
alpha- | hexyl cinnamaldehyde | FL/FR |
| hydroxycitronellal | FL/FR |
woody |
iso | bornyl acetate | FL/FR |
iso | bornyl formate | FL/FR |
| dehydroxylinalool oxide | FL/FR |
iso | pulegyl acetate | FL/FR |
|
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| benzoic acid, 2-hydroxy-, methyl ester | synthetic sweet | birch oil | | birch-me | 2- | carbomethoxyphenol | | hewedolor | 2- | hydroxybenzoic acid methyl ester | o- | hydroxybenzoic acid methyl ester | ortho- | hydroxybenzoic acid methyl ester | | linsal | 2-( | methoxycarbonyl) phenol | 2-( | methoxycarbonyl)phenol | | methyl 2-hydroxybenzoate | | methyl o-hydroxybenzoate | | methyl ortho-hydroxybenzoate | | methyl salicylate (+) | | methyl salicylate BP | | methyl salicylate extra pure | | methyl salicylate FCC | | methyl salicylate fractions | | methyl salicylate low phenol | | methyl salicylate natural | | methyl salicylate NF FCC | | methyl salicylate NF grade | | methyl salicylate synthetic | | methyl salicylate synthetic NF/FCC | | methyl salicylate USP | | methylsalicylate | | metsal liniment | | rheumabal | | rhodiaflor | | salicylic acid methyl ester | synthetic | teaberry oil | synthetic | wintergreen oil |
Articles:
PubMed: | Postharvest biology and technology of pomegranate. |
PubMed: | Fractionation and identification of minor and aroma-active constituents in Kangra orthodox black tea. |
PubMed: | Role of internal atmosphere on fruit ripening and storability-a review. |
PubMed: | Inoculation of the nonlegume Capsicum annuum L. with Rhizobium strains. 2. Changes in sterols, triterpenes, fatty acids, and volatile compounds. |
PubMed: | Efficient scavenging of β-carotene radical cations by antiinflammatory salicylates. |
PubMed: | New chemical constituents from Oryza sativa straw and their algicidal activities against blue-green algae. |
PubMed: | Static liquid permeation cell method for determining the migration parameters of low molecular weight organic compounds in polyethylene terephthalate. |
PubMed: | Apple volatiles synergize the response of codling moth to pear ester. |
PubMed: | Assessment of potential causes of falsely positive Mycobacterium tuberculosis breath test. |
PubMed: | Profiling of volatile compounds of Phyllostachys pubescens shoots in Taiwan. |
PubMed: | What happens if people start drinking mouthwash as surrogate alcohol? A quantitative risk assessment. |
PubMed: | Volatiles from apple trees infested with light brown apple moth larvae attract the parasitoid Dolichogenidia tasmanica. |
PubMed: | Hull split and damaged almond volatiles attract male and female navel orangeworm moths. |
PubMed: | Sequence comparisons of odorant receptors among tortricid moths reveal different rates of molecular evolution among family members. |
PubMed: | The estrogenic potential of salicylate esters and their possible risks in foods and cosmetics. |
PubMed: | Methyl salicylate-induced arginine catabolism is associated with up-regulation of polyamine and nitric oxide levels and improves chilling tolerance in cherry tomato fruit. |
PubMed: | Vicia faba Hypersensitivity and ASA Intolerance in a Farmer: A Case Report. |
PubMed: | Methyl salicylate attracts natural enemies and reduces populations of soybean aphids (Hemiptera: Aphididae) in soybean agroecosystems. |
PubMed: | Evaluation of genotype and environment effects on taste and aroma flavor components of Spanish fresh tomato varieties. |
PubMed: | Leaf volatile emissions of Betula pendula during autumn coloration and leaf fall. |
PubMed: | Effect of methyl salicylate-based lures on beneficial and pest arthropods in strawberry. |
PubMed: | Efficacy and safety profile of a topical methyl salicylate and menthol patch in adult patients with mild to moderate muscle strain: a randomized, double-blind, parallel-group, placebo-controlled, multicenter study. |
PubMed: | Levels of mint and wintergreen flavorants: smokeless tobacco products vs. confectionery products. |
PubMed: | Elicitation of pharmacologically active substances in an intact medical plant. |
PubMed: | Odorant receptors from the light brown apple moth (Epiphyas postvittana) recognize important volatile compounds produced by plants. |
PubMed: | Oriented responses of grapevine moth larvae Lobesia botrana to volatiles from host plants and an artificial diet on a locomotion compensator. |
PubMed: | Field-testing of synthetic herbivore-induced plant volatiles as attractants for beneficial insects. |
PubMed: | Repellency of an over-the-counter essential oil product in China against workers of red imported fire ants. |
PubMed: | The use of a semiochemical bait to enhance exposure of Amblyomma variegatum (Acari: Ixodidae) to Metarhizium anisopliae (Ascomycota: Hypocreales). |
PubMed: | Floral attractants for the female soybean looper, Thysanoplusia orichalcea (Lepidoptera: Noctuidae). |
PubMed: | Predatory mite attraction to herbivore-induced plant odors is not a consequence of attraction to individual herbivore-induced plant volatiles. |
PubMed: | Fragrance material review on methyl salicylate. |
PubMed: | First report of an attractant for a tumbling flower beetle (Coleoptera: Mordellidae). |
PubMed: | Influence of the application of three different elicitors on soybean plants on the concentrations of several isoflavones in soybean seeds. |
PubMed: | Antifungal activities of major tea leaf volatile constituents toward Colletorichum camelliae Massea. |
PubMed: | Salicylate activity. 2. Potentiation of atrazine. |
PubMed: | Salicylate activity. 1. Protection of plants from paraquat injury. |
PubMed: | Stable isotope characterization of the ortho-oxygenated phenylpropanoids: coumarin and melilotol. |
PubMed: | Effects of cyclamen mite (Phytonemus pallidus) and leaf beetle (Galerucella tenella) damage on volatile emission from strawberry (Fragaria x ananassa Duch.) plants and orientation of predatory mites (Neoseiulus cucumeris, N. californicus, and Euseius finlandicus). |
PubMed: | The involvement of volatile infochemicals from spider mites and from food-plants in prey location of the generalist predatory mite Neoseiulus californicus. |
PubMed: | Natural abundance 2H-ERETIC-NMR authentication of the origin of methyl salicylate. |
PubMed: | Effect of volatile constituents from Securidaca longepedunculata on insect pests of stored grain. |
PubMed: | Hydrolysis of glycosidically bound volatiles from apple leaves (Cv. Anna) by Aspergillus niger beta-glucosidase affects the behavior of codling moth (Cydia pomonella L.). |
PubMed: | Contaminants and levels of occurrence in washed and shredded poly(ethylene terephthalate) from curbside collection. Part 1: Extraction conditions. |
PubMed: | Ovicidal and adulticidal effects of Eugenia caryophyllata bud and leaf oil compounds on Pediculus capitis. |
PubMed: | Aerosolized essential oils and individual natural product compounds as brown treesnake repellents. |
PubMed: | Composition of the volatiles from intact and mechanically pierced tea aphid-tea shoot complexes and their attraction to natural enemies of the tea aphid. |
PubMed: | Plant odor analysis of apple: antennal response of codling moth females to apple volatiles during phenological development. |
PubMed: | Analysis of glycosidically bound aroma precursors in tea leaves. 1. Qualitative and quantitative analyses of glycosides with aglycons as aroma compounds. |
PubMed: | (Z)-3-hexenyl and trans-linalool 3,7-oxide beta-primeverosides isolated as aroma precursors from leaves of a green tea cultivar. |
PubMed: | Airway morphology and function of rats following dermal sensitization and respiratory challenge with low molecular weight chemicals. |
PubMed: | Local lymph node activation and IgE responses in brown Norway and Wistar rats after dermal application of sensitizing and non-sensitizing chemicals. |
PubMed: | Characterization of esterase and alcohol dehydrogenase activity in skin. Metabolism of retinyl palmitate to retinol (vitamin A) during percutaneous absorption. |
PubMed: | Drugs in the food supply. |
PubMed: | Evaluation of safety for food additives: An illustration involving the influence of methyl salicylate on rat reproduction. |
|