Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | Colorless to yellow clear liquid (est) |
Assay: | 97.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Specific Gravity: | 1.09100 to 1.09700 @ 25.00 °C.
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Pounds per Gallon - (est).: | 9.078 to 9.128
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Refractive Index: | 1.47500 to 1.48100 @ 20.00 °C.
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Boiling Point: | 221.00 to 222.00 °C. @ 760.00 mm Hg
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Acid Value: | 3.00 max. KOH/g
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Vapor Pressure: | 0.103000 mmHg @ 25.00 °C. (est) |
Flash Point: | 162.00 °F. TCC ( 72.22 °C. )
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logP (o/w): | 0.269 (est) |
Soluble in: |
| alcohol | | water, 2.441e+004 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
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Odor Type: moldy |
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Odor Strength: | high , recommend smelling in a 1.00 % solution or less |
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Substantivity: | > 384 hour(s) at 100.00 % |
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| sweet moldy mushroom vegetable potato sugar burnt sugar nut skin wasabi caramellic fruity brandy |
Odor Description: at 1.00 % in dipropylene glycol. | sweet moldy mushroom vegetable potato burnt sugar nut skin wasabi caramellic fruity brandy Luebke, William tgsc, (2017) |
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| musty sweet caramellic musty beany cocoa coffee meaty vegetable |
Odor Description: at 1.00 % in propylene glycol. | Musty, sweet, caramellic, musty beany, cocoa, coffee with slightly meaty and vegetative nuances Mosciano, Gerard P&F 24, No. 5, 41, (1999) |
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Flavor Type: moldy |
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| moldy earthy vegetable potato savory brown meaty |
Taste Description:
| moldy earthy vegetable potato savory brown meaty Luebke, William tgsc, (2017) |
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| musty vegetable savory meaty brown jammy |
Taste Description: at 1.00 - 5.00 ppm. | Musty, vegetative, savory meaty with a brown jammy fullness in the aftertaste Mosciano, Gerard P&F 24, No. 5, 41, (1999) |
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Odor and/or flavor descriptions from others (if found). |
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Sigma-Aldrich |
2,5-Dimethyl-4-methoxy-3(2H)-furanone, ≥97%, FG |
Odor Description: | caramel; grape; maple; mushroom; mossy; potato; coffee; nutty; meaty |
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Firmenich |
FURANEOL® METHYLETHER Kosher for flavor |
Taste Description: | Burnt sugar metallic musty raw potato vegetable and bready notes FURANEOL® METHYLETHER brings along with its typical caramelic character, slight meaty and green nuances which work perfectly in strawberry, crab, orange, forest fruits and banana flavors. |
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Cosmetic Information:
Suppliers:
Advanced Biotech |
MESIFURAN 20% ETOH NATURAL
Odor: Burnt Sugar |
Advanced Biotech |
MESIFURAN 20% IN PG NATURAL
Odor: Burnt sugar |
Advanced Biotech |
MESIFURAN 20% IN PG SYNTHETIC
Odor: Burnt sugar |
Advanced Biotech |
MESIFURAN SYNTHETIC
98% min. Odor: Burnt sugar |
Anhui Haibei |
4-Methoxy-2,5-dimethyl-3(2H)-furanone
Odor: Sweet mildew moldy maple fruity |
Augustus Oils |
2,5 Dimethyl 4 Methoxy 3 Furanone
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Services |
Aurochemicals |
MESIFURAN 20% IN PG, Natural
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Beijing Lys Chemicals |
2,5-Dimethyl-4-methoxy-2,3-dihydro-furan-3-one
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BOC Sciences |
For experimental / research use only. |
4-Methoxy-2,5-dimethyl-3(2H)-furanone
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Carbosynth |
For experimental / research use only. |
4-Methoxy-2,5-dimethyl-3(2H)-furanone
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Endeavour Specialty Chemicals |
4-Methoxy-2,5-dimethyl-3(2H)-furanone
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Speciality Chemical Product Groups |
Firmenich |
FURANEOL® METHYLETHER Kosher
for flavor Flavor: Burnt sugar metallic musty raw potato vegetable and bready notes FURANEOL® METHYLETHER brings along with its typical caramelic character, slight meaty and green nuances which work perfectly in strawberry, crab, orange, forest fruits and banana flavors. |
H. Interdonati, Inc. |
Berry Furanone Kosher
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Featured Products |
Jiangyin Healthway |
4-Methoxy-2.5-dimethyl-3(2H)-furanone
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New functional food ingredients |
Lluch Essence |
FURANEOL METHYL ETHER NATURAL
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Lluch Essence |
FURANEOL METHYL ETHER
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M&U International |
Fraision Methyl Ether, Kosher
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Natural Advantage |
Mesifurane Nat
Flavor: caramellic, fruity, sherry, sweet |
Riverside Aromatics LTD.is the exclusive distributor for Europe in UK for any non-US based inquiries |
Penta International |
2,5-DIMETHYL-4-METHOXY-3(2H)FURANONE NATURAL
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Penta International |
2,5-DIMETHYL-4-METHOXY-3(2H)FURANONE
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Phoenix Aromas & Essential Oils |
Fraision Methyl Ether
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R C Treatt & Co Ltd |
4-Methoxy-2,5-dimethyl-3(2H)furanone
Halal, Kosher |
Riverside Aromatics |
4-METHOXY-2,5-DIMETHYL-3-(2H)-FURANONE, NATURAL
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Robinson Brothers |
4-Methoxy-2,5-dimethyl-3(2H)-furanone F&F
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https://www.robinsonbrothers.uk/chemistry-competences |
Sigma-Aldrich |
2,5-Dimethyl-4-methoxy-3(2H)-furanone, ≥97%, FG
Odor: caramel; grape; maple; mushroom; mossy; potato; coffee; nutty; meaty |
Certified Food Grade Products |
Sigma-Aldrich |
2,5-Dimethyl-4-methoxy-3(2H)-furanone, natural, ≥98%, FG
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Sunaux International |
Fraision Methyl Ether
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Synerzine |
2,5-Dimethyl-4-methoxy 3(2H) Furanone
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TCI AMERICA |
For experimental / research use only. |
2,5-Dimethyl-4-methoxy-3(2H)-furanone >97.0%(GC)
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Tianjin Danjun International |
2,5-Dimethyl-4-methoxy-2,3-dihydro-furan-3-one
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United International |
4-Methoxy-2,5-Dimethyl-3(2h)-Furanone
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WholeChem |
2,5-Dimethyl-4-methoxy-2,3-dihydro-furanone
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Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xi - Irritant |
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for strawberry furanone methyl ether usage levels up to: | | 0.5000 % in the fragrance concentrate.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 19.00 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.70 (μg/capita/day) |
Structure Class: | II |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 13 |
Click here to view publication 13 |
| average usual ppm | average maximum ppm |
baked goods: | - | 12.00000 |
beverages(nonalcoholic): | - | 0.50000 |
beverages(alcoholic): | - | 1.00000 |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | 10.00000 |
condiments / relishes: | - | - |
confectionery froastings: | - | 2.50000 |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 3.00000 |
fruit ices: | - | 3.00000 |
gelatins / puddings: | - | 5.00000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 5.00000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | 2.50000 |
meat products: | - | - |
milk products: | - | 2.50000 |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | 2.50000 |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 220: alpha,beta-Unsaturated ketones and precursors from chemical subgroup 4.4 of FGE.19: 3(2H)-Furanones View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 220, Revision 1 (FGE.220Rev1): alpha,beta-Unsaturated ketones and precursors from chemical subgroup 4.4 of FGE.19: 3(2H)-Furanones View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 220, Revision 2 (FGE.220Rev1): a,ß-Unsaturated ketones and precursors from chemical subgroup 4.4 of FGE.19: 3(2H)-Furanones View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 220 Revision 3 (FGE.220Rev3): Consideration of genotoxic potential for a,ß-unsaturated 3(2H)-Furanones from subgroup 4.4 of FGE.19 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 99 Revision 1 (FGE.99Rev1): Consideration of furanone derivatives evaluated by the JECFA (63rd, 65th and 69th meetings) View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 4077-47-8 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 61325 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 3 |
| 4-methoxy-2,5-dimethylfuran-3-one |
Chemidplus: | 0004077478 |
References:
Other Information:
Potential Blenders and core components note
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For Odor |
alcoholic |
alcoholic |
sec- | hexyl alcohol | FL/FR |
alliaceous |
| dimethyl trisulfide | FL/FR |
amber |
| labdanum absolute | FL/FR |
balsamic |
(E)- | benzyl tiglate | FL/FR |
burnt |
(R)-2- | methyl butyraldehyde | |
buttery |
| acetoin | FL/FR |
| caramel pentadione | FL/FR |
| cyclotene | FL/FR |
| cyclotene hydrate | FL/FR |
alpha,alpha- | dimethyl anisyl acetone | FL/FR |
| ethyl 2-hydroxy-2-methyl butyrate | FL/FR |
| ethyl cyclopentenolone | FL/FR |
| ethyl maltol | FL/FR |
5- | ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one | FL/FR |
| fenugreek absolute | FL/FR |
| fenugreek oleoresin | FL/FR |
| geranyl crotonate | FR |
cis-2- | hydroxy-3,4,5-trimethyl-2-cyclopenten-1-one | |
| immortelle absolute | FL/FR |
| maltol | FL/FR |
| maltyl propionate | FL/FR |
| maple furanone | FL/FR |
| menthone lactone | FL/FR |
| mesitene lactone | FR |
| rosefuran | FL/FR |
| shoyu furanone | FL/FR |
| strawberry furanone | FL/FR |
| toffee furanone | FL/FR |
citrus |
| methyl heptenone | FL/FR |
cocoa |
2- | methyl butyraldehyde | FL/FR |
coumarinic |
| tonka bean resinoid | FR |
earthy |
| root fragrance | FR |
ethereal |
| acetal | FL/FR |
iso | valeraldehyde propylene glycol acetal | FL/FR |
fatty |
(R)-gamma- | decalactone | FL/FR |
fruity |
iso | amyl isovalerate | FL/FR |
| ethyl (Z)-4-heptenoate | FL/FR |
(S)-2- | methyl butyraldehyde | |
2- | methyl-2-pentenal | FL/FR |
green |
2-sec- | butyl-3-methoxypyrazine | FL/FR |
3- | heptanone | FL/FR |
herbal |
(S)- | campholene acetate | FL/FR |
(S)-2- | ethyl hexanoic acid | |
| trigonella foenum-graecum seed extract | FL/FR |
nutty |
2- | acetyl-3-ethyl pyrazine | FL/FR |
2,3,5,6- | tetramethyl pyrazine | FL/FR |
| fenugreek resinoid | FL/FR |
| trigonella foenum-graecum seed oil CO2 extract | FL/FR |
| furfuryl thioacetate | FL/FR |
sweet |
| vanilla oleoresin bali | FL/FR |
vanilla |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
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For Flavor |
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No flavor group found for these |
2- | acetyl-3,4,5,6-tetrahydropyridine | FL |
2- | acetyl-6-methyl pyrazine | FL |
| allyl 2-furoate | FL |
(R)-gamma- | decalactone | FL/FR |
2,5- | diethyl tetrahydrofuran | FL |
alpha,alpha- | dimethyl anisyl acetone | FL/FR |
| ethyl 2-hydroxy-2-methyl butyrate | FL/FR |
(S)-2- | ethyl hexanoic acid | |
3- | ethyl thiopropanol | FL |
5- | ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one | FL/FR |
sec- | hexyl alcohol | FL/FR |
cis-2- | hydroxy-3,4,5-trimethyl-2-cyclopenten-1-one | |
| menthone lactone | FL/FR |
| methyl 2-hydroxy-4-methyl valerate | FL |
S- | methyl benzothioate | FL |
(S)-2- | methyl butyraldehyde | |
(R)-2- | methyl butyraldehyde | |
| rosefuran | FL/FR |
acidic |
dextro,laevo- | tartaric acid | FL |
alliaceous |
| dimethyl trisulfide | FL/FR |
amber |
| labdanum absolute | FL/FR |
balsamic |
(E)- | benzyl tiglate | FL/FR |
bready |
| trigonella foenum-graecum seed extract | FL/FR |
brown |
| fenugreek oleoresin | FL/FR |
burnt |
| furfuryl alcohol | FL |
caramellic |
| caramel dione | FL |
| caramel furanone | FL |
| caramel pentadione | FL/FR |
| cyclotene | FL/FR |
| cyclotene hydrate | FL/FR |
| ethyl maltol | FL/FR |
5- | ethyl-3,4,5,6-tetramethyl cyclohexen-2-one | FL |
| fenugreek absolute | FL/FR |
| fenugreek resinoid | FL/FR |
| maltol | FL/FR |
| maltyl propionate | FL/FR |
| maple furanone | FL/FR |
| shoyu furanone | FL/FR |
| strawberry furanone | FL/FR |
| toffee furanone | FL/FR |
coffee |
| coffee distillates | FL |
creamy |
| acetoin | FL/FR |
earthy |
| panax quinquefolius root extract | FL |
fatty |
(E,E)-2,4- | undecadienal | FL |
2,4- | undecadienal | FL |
fruity |
| ethyl (Z)-4-heptenoate | FL/FR |
2- | methyl-2-pentenal | FL/FR |
2- | pentanoyl furan | FL |
iso | valeraldehyde propylene glycol acetal | FL/FR |
fusel |
2- | methyl butyraldehyde | FL/FR |
green |
iso | amyl isovalerate | FL/FR |
| immortelle absolute | FL/FR |
| methyl heptenone | FL/FR |
| propylene glycol acetone ketal | FL |
jammy |
(S)- | campholene acetate | FL/FR |
| ethyl cyclopentenolone | FL/FR |
ketonic |
3- | heptanone | FL/FR |
meaty |
(R,S)-2- | mercapto-3-butanol | FL |
musty |
2- | ethoxythiazole | FL |
| propionaldehyde | FL |
nutty |
| acetal | FL/FR |
2- | acetyl-3-ethyl pyrazine | FL/FR |
| aconitic acid | FL |
| nutty thiazole | FL |
2,3,5,6- | tetramethyl pyrazine | FL/FR |
roasted |
| furfuryl thioacetate | FL/FR |
| trigonella foenum-graecum seed oil CO2 extract | FL/FR |
smoky |
dextro- | xylose | FL |
sulfurous |
| butyl mercaptan | FL |
| furfuryl thiopropionate | FL |
2- | naphthyl mercaptan | FL |
| potato butanone | FL |
sweet |
| vanilla oleoresin bali | FL/FR |
vanilla |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
vegetable |
2-sec- | butyl-3-methoxypyrazine | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| berry furanone | 2,5- | dimethyl-4-methoxy 3(2H) furanone | 2,5- | dimethyl-4-methoxy-2,3-dihydro-3-furanone | 2,5- | dimethyl-4-methoxy-2,3-dihydro-furan-3-one | 2,5- | dimethyl-4-methoxy-3(2H)-furanone | 2,5- | dimethyl-4-methoxy-3(2H)furanone | 2,5- | dimethyl-4-methoxy-3(2H)furanone natural | 2,5- | dimethyl-4-methoxy-3[2H]-furanone | 2,5- | dimethyl-4-methoxyfuran-3(2H)-one | 2,5- | dimethyl-4-methyoxy-2H-furan-3-one | | fraision methyl ether | | furaneol methyl ether | | furaneol methylether (Firmenich) | 3[2H]- | furanone, 2,5-dimethyl-4-methoxy- | 3(2H)- | furanone, 4-methoxy-2,5-dimethyl- | | mesifuran | | mesifuran 20% in PG natural | | mesifuran 20% in PG synthetic | | mesifuran synthetic | | mesifurane | 4- | methoxy-2,5-dimethyl-2-hydrofuran-3-one | 4- | methoxy-2,5-dimethyl-2,3-dihydrofuran-3-one | 4- | methoxy-2,5-dimethyl-3 2H-furanone | 4- | methoxy-2,5-dimethyl-3(2H)-furanone | 4- | methoxy-2,5-dimethyl-3(2H)furanone | 4- | methoxy-2,5-dimethylfuran-3-one | 4- | methoxy-2,5-dimethylfuran-3(2H)-one | | methoxyfuraneol |
Articles:
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