Category: antioxidants and preservatives for fragrance and flavor
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | white to pale yellow solid (est) |
Assay: | 98.00 to 100.00 %
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Food Chemicals Codex Listed: | Yes |
Melting Point: | 58.00 to 60.00 °C. @ 760.00 mm Hg
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Boiling Point: | 268.00 to 269.00 °C. @ 760.00 mm Hg
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Vapor Pressure: | 0.004000 mmHg @ 25.00 °C. (est) |
Vapor Density: | 6.2 ( Air = 1 ) |
Flash Point: | 235.00 °F. TCC ( 112.78 °C. )
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logP (o/w): | 3.087 (est) |
Shelf Life: | 24.00 month(s) or longer if stored properly. |
Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
Soluble in: |
| alcohol | | water, 212.8 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
Odor Strength: | low |
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Odor Description: at 100.00 %. | mild rubbery |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xn - Harmful. |
R 22 - Harmful if swallowed. R 40 - Possible risks of irreversable effects. S 02 - Keep out of the reach of children. S 22 - Do not breath dust. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
oral-rat LD50 2000 mg/kg BEHAVIORAL: ATAXIA
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. Vol. 22, Pg. 231, 1970.
intraperitoneal-rat LD50 881 mg/kg BLOOD: HEMORRHAGE Toxicology Letters. Vol. 27, Pg. 15, 1985.
oral-mouse LD50 1100 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
BEHAVIORAL: ATAXIA
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. Vol. 22, Pg. 231, 1970.
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | antioxidants and preservatives for fragrance and flavor |
Recommendation for butylated hydroxyanisole usage levels up to: | | not for fragrance use.
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Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | - | 2.80000 |
beverages(nonalcoholic): | - | 0.82000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | 13.00000 |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | 230.00000 |
fish products: | - | - |
frozen dairy: | - | 0.81000 |
fruit ices: | - | 0.81000 |
gelatins / puddings: | - | 0.54000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 9.60000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | 5.00000 |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Authority (EFSA) reference(s): |
Scientific Opinion on the re-evaluation of butylated hydroxyanisole – BHA (E 320) as a food additive View page or View pdf |
Statement on the safety assessment of the exposure to butylated hydroxyanisole E 320 (BHA) by applying a new exposure assessment methodology View page or View pdf |
Safety and efficacy of butylated hydroxyanisole (BHA) as a feed additive for all animal species View page or View pdf |
Safety of butylated hydroxy anisole (BHA) for all animal species View page or View pdf |
EPI System: | View |
Chemical Carcinogenesis Research Information System: | Search |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
Carcinogenic Potency Database: | Search |
EPA GENetic TOXicology: | Search |
EPA Substance Registry Services (TSCA): | 25013-16-5 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 24667 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 2 |
| 2-tert-butyl-4-methoxyphenol;3-tert-butyl-4-methoxyphenol |
Chemidplus: | 0025013165 |
EPA/NOAA CAMEO: | hazardous materials |
RTECS: | SL1945000 for cas# 25013-16-5 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
| antioxidants | |
| preservatives | |
Occurrence (nature, food, other): note
Synonyms:
| antioxyne B | | B.H.A. | | BHA | | BHA food grade NF | | butyl hydroxyanisole | tert- | butyl hydroxyanisole | 2(3)-t- | butyl-4-hydroxyanisole | 2(3)-tert- | butyl-4-hydroxyanisole | tert- | butyl-4-hydroxyanisole | 2(3)-tert- | butyl-4-methoxyphenol | tert- | butyl-4-methoxyphenol | 2-tert- | butyl-4-methoxyphenol;3-tert-butyl-4-methoxyphenol | 3-tert- | butyl-4-methoxyphenyl and 2tert-butyl-4-methoxyphenol | 2-tert- | butyl-4-methoxyphenyl and 3-tert-butyl-4-methoxyphenol | 2(3)-(tert- | butyl)-4-methoxyphenol | tert- | butylhydroxyanisole | (1,1- | dimethyl ethyl)-4-methoxyphenol | 2(3)-(1,1- | dimethylethyl)-4-(methyloxy)phenol | 2(3)-(1,1- | dimethylethyl)-4-methoxy-phenol | 2(or 3)-(1,1- | dimethylethyl)-4-methoxyphenol | | embanox | butylated | hydroxy anisole (BHA) EP/NF powder (40 mesh) | butylated | hydroxy anisole (BHA) NF / FCC grade | butylated | hydroxy anisole EP grade | 4- | hydroxy-2(3)-tert-butylanisole | butylated | hydroxyanisole (BHA) EP / IP grade | butylated | hydroxyanisole (BHA) EP / NF grade | butylated | hydroxyanisole (BHA) FCC | butylated | hydroxyanisole (BHA) N.F. | butylated | hydroxyanisole (BHA) NF/FCC powder (40 mesh) | 4- | methoxy-2(3)-tert-butylphenol | | phenol, (1,1-dimethylethyl)-4-methoxy- | | phenol, 2(3)-(1,1-dimethylethyl)-4-methoxy- | | phenol, 2(3)-t-butyl-4-methoxy- | | phenol, 2(3)-tert-butyl-4-methoxy- | | phenol, t-butyl-4-methoxy- | | tenox BHA food grade antioxidant, flake |
Articles:
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