Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Organoleptic Properties:
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Odor Type: floral |
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Odor Strength: | medium , recommend smelling in a 10.00 % solution or less |
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Substantivity: | 48 hour(s) at 100.00 % |
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| clover herbal orchid floral |
Odor Description: at 10.00 % in dipropylene glycol. | clover herbal orchid floral Luebke, William tgsc, (1989) |
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| sweet spicy cooling wintergreen |
Odor Description:
| Sweet, spice, cooling, with a wintergreen nuance Mosciano, Gerard P&F 17, No. 4, 33, (1992) |
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Flavor Type: cooling |
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| sweet cooling spicy fruity |
Taste Description: at 3.00 ppm. | Sweet, cooling, spicy with fruity nuances Mosciano, Gerard P&F 17, No. 4, 33, (1992) |
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Odor and/or flavor descriptions from others (if found). |
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Symrise |
Isobutyl Salicylate |
Odor Description: | wintergreen-like, sweet herbaceous-green, slightly floral, with orchid-like nuances |
Taste Description: | sweet cooling spicy fruity |
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Moellhausen |
isoBUTYL SALICYLATE |
Odor Description: | aromatic, herbaceous, floreal |
Taste Description: | sweet aromatic; cooling, spicy with fruity nuances |
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Cosmetic Information:
Suppliers:
Augustus Oils |
Iso Butyl Salicylate
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Services |
Berjé |
isoButyl Salicylate
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Media |
BOC Sciences |
For experimental / research use only. |
isoButyl Salicylate
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Ernesto Ventós |
IsoBUTYL SALICYLATE
Odor: SWEET, HARSH, HERBAL, FLORAL |
Global Essence |
isoButyl Salicylate
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Indukern F&F |
ISOBUTYL SALICYLATE
Odor: SWEET, HERBAL, FLORAL |
Keva |
ISOBUTYL SALICYLATE
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Liaison Carbone |
isoBUTYL SALICYLATE
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Lluch Essence |
ISOBUTYL SALICYLATE
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M&U International |
isoBUTYL SALICYLATE
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Moellhausen |
isoBUTYL SALICYLATE
Odor: aromatic, herbaceous, floreal Flavor: sweet aromatic; cooling, spicy with fruity nuances |
Penta International |
ISOBUTYL SALICYLATE FCC
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PerfumersWorld |
isoButyl Salicylate
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Reincke & Fichtner |
isoButyl Salicylate
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Seqens |
isoButyl Salicylate, Kosher
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Sigma-Aldrich |
Isobutyl salicylate, ≥98%, FCC
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Certified Food Grade Products |
SRS Aromatics |
ISO BUTYL SALICYLATE
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Symrise |
Isobutyl Salicylate
Odor: wintergreen-like, sweet herbaceous-green, slightly floral, with orchid-like nuances |
Synerzine |
isoButyl Salicylate
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TCI AMERICA |
For experimental / research use only. |
isoButyl Salicylate >99.0%(GC)
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The Good Scents Company |
isobutyl salicylate
Odor: clover herbal orchid floral |
The John D. Walsh Company |
IsoButyl Salicylate
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The Perfumers Apprentice |
isoButyl Salicylate
Odor: sweet, spice, cooling, with a wintergreen nuance Use: useful in many types of soft floral and herbal fragrances |
U. K. Aromatics and Chemicals |
ISOBUTYL SALICYLATE
Odor: clover herbal orchid floral Flavor: Peach, Mulberry, Raspberry |
Vigon International |
isoButyl Salicylate FCC
Odor: CLOVE-ORCHID |
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xn - Harmful. |
R 22 - Harmful if swallowed. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
Acute toxicity, Oral (Category 4), H302
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GHS Label elements, including precautionary statements |
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Pictogram | |
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Signal word | Warning |
Hazard statement(s) |
H302 - Harmful if swallowed
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Precautionary statement(s) |
P264 - Wash skin thouroughly after handling. P270 - Do not eat, drink or smoke when using this product. P301 + P312 - IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P330 - Rinse mouth. P501 - Dispose of contents/ container to an approved waste disposal plant.
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Human Experience: |
10 % solution: no irritation or sensitization. |
Oral/Parenteral Toxicity: |
oral-rat LD50 1560 mg/kg (Moreno, 1973aa)
oral-mouse LD50 5100 mg/kg Food and Cosmetics Toxicology. Vol. 13, Pg. 813, 1975.
oral-mouse LD50 5100 mg/kg Toksikologicheskii Vestnik. Vol. (2), Pg. 25, 1994.
oral-rat LD50 1560 mg/kg Food and Cosmetics Toxicology. Vol. 13, Pg. 813, 1975.
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Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 13, Pg. 813, 1975.
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
maximum skin levels for fine fragrances: | | 0.8100 % and are based on the assumption that the fragrance mixture is used at 20% in a consumer product (IFRA Use Level Survey). (IFRA, 2002)
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Recommendation for isobutyl salicylate usage levels up to: | | 2.0000 % in the fragrance concentrate.
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use level in formulae for use in cosmetics: | | 0.1680 %
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Dermal Systemic Exposure in Cosmetic Products: | | 0.0043 mg/kg/day (IFRA, 2002)
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.97 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 6.00 (μg/capita/day) |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | - | 5.00000 |
beverages(nonalcoholic): | - | 3.50000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 1.80000 |
fruit ices: | - | 1.80000 |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 2.60000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s): |
The FEMA GRAS assessment of hydroxyl- and alkoxy-substituted benzyl derivatives used as flavor ingredients. View pdf |
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23 View page or View pdf |
Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 87-19-4 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 6873 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 3 |
| 2-methylpropyl 2-hydroxybenzoate |
Chemidplus: | 0000087194 |
RTECS: | VO4320000 for cas# 87-19-4 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| benzoic acid, 2-hydroxy-, 2-methylpropyl ester | 2-iso | butoxycarbonyl phenol | 2-iso | butoxycarbonylphenol | iso | butyl 2-hydroxybenzoate | iso | butyl o-hydroxybenzoate | iso | butyl ortho-hydroxybenzoate | iso | butyl salicylate FCC | iso | butylsalicylate | 2- | hydroxybenzoic acid 2-methyl propyl ester | 2- | hydroxybenzoic acid 2-methylpropyl ester | 2- | hydroxybenzoic acid isobutyl ester | 2- | methyl propyl 2-hydroxybenzoate | 2- | methyl propyl o-hydroxybenzoate | 2- | methyl propyl ortho-hydroxybenzoate | 2- | methyl-1-propyl salicylate | 2- | methylpropyl 2-hydroxybenzoate | 2- | methylpropyl o-hydroxybenzoate | | salicylic acid isobutyl ester | | salicylic acid, isobutyl ester |
Articles:
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