ascorbic acid
(5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one
 
Notes:
a six carbon compound related to glucose. it is found naturally in citrus fruits and many vegetables. ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. its biologically active form, vitamin c, functions as a reducing agent and coenzyme in several metabolic pathways. vitamin c is considered an antioxidant. The L-form Occurs widely in animals and plants. Good sources are citrus fruits and hip berries. Isol. from ox adrenal cortex, lemons and paprika. [CCD] Occurs widely in animals and plants. Good sources are citrus fruits and hip berries. Isol. from ox adrenal cortex, lemons and paprika. Prod. industrially on a large scale from glucose. Vitamin (antiscorbutic), antioxidant, nutrient, preservative consistency enhancer. Used to reduce discoloration, mainly browning caused by polyphenol oxidase, in fruit and vegetable products. Used to enhance colour formn. and to reduced the formn. of nitrosamines in meat products. Used synergistically with Sulfur dioxide HVF10-P in wine and beer as a perservative. Assists formn. of the gluten network in bread making, thus enhancing bread volume
  • American International Chemical, LLC.
    • American International Chemical, Inc.
      Consistent sources
      North American supplier for globally sourced ingredients.
      AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it.
      Email: Info
      Voice: (800) 238-0001
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      Products List: View
      Product(s):
      VICAUG Vitamin C
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
      Email: Marketing
      US Email: Marketing
      Email: Sales
      US Email: Sales
      Voice: 1-631-485-4226
      Fax: 1-631-614-7828
      US Voice: 1-631-485-4226
      US Fax: 1-631-614-7828
      Europe44-203-286-1088
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      Product(s):
      50-81-7 Vitamin C >98%
      Ascorbic acid is a naturally occurring organic compound with antioxidant properties. antioxidant
       
       
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
      Email: Sales
      Voice: 203-299-3220
      Fax: 203-299-1355
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      Products List: View
      Product(s):
      ASCORBIC ACID
       
  • ECSA Chemicals
    • ECSA Chemicals
      Human Chemistry
      ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of the largest distributors worldwide.
      ECSA Chemicals is the largest Swiss-owned company in terms of warehouses for the distribution of chemical products. We have been distributing chemical products for over 100 years and we have a special interest in protecting the environment and in the safety of our facilities and collaborators.
      Established in 1913 as a small grocery store, in its over 100 years of activity ECSA Chemicals has become one of the most important Swiss-owned distributors of chemical products. The company, which is active in international distribution and trading, is organised into industrial segments that are managed by teams of specialists and experts. They guarantee professional and customised consultancy and services. With our experience, we can rapidly and safely connect you with the best suppliers on the market, providing you with a complete search, consulting and assistance service. The focus of our approach and operations is you, our customers. We strive every day to find the best products that satisfy your needs as quickly as possible. Your satisfaction is our greatest success. WHY CHOOSE ECSA? EXPERIENCE We have been working for 100 years. QUALITY We have obtained many certifications (ISO, SQAS, GDP, Responsible Care, Bio-Inspecta, RSPO, etc.). We guarantee full compliance with the current laws and continuous training for our staff. SAFETY We constantly carry out risk analyses for each infrastructure, defining safety levels and implementing corrective measures promptly wherever they are needed. WIDESPREAD DISTRIBUTION We have warehouses in strategic locations to supply goods to Switzerland and to the rest of the world. STORAGE CAPACITY The 3 ECSA-owned warehouses guarantee considerable storage area and capacity in each warehouse, with full availability of products (base chemicals and speciality chemicals). SPEED Presence all over the country, staff dedicated to sourcing raw materials and considerable storage capacity guarantee that goods are rapidly obtained and supplied. CONSULTANCY Our specialists - in-depth knowledge of the market and products allows us to provide full consulting services, from the purchase to the supply of raw materials.
      Email: Info
      Email: Sales
      Email: Trading
      Email: Maintenance
      Email: Energy
      Voice: +41 91 695 88 00
      Fax: +41 91 695 88 01
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      ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
      Products List: View
      Product(s):
      MP-020438 VITAMIN C / ASCORBIC ACID BP/USP/PH.EUR
      MP-022830 VITAMIN C / ASCORBIC ACID COATED
      RE-402407 L(+)ASCORBIC ACID RPE-ISO-FOR ANALYSIS, KG 1
       
  • Glentham Life Sciences
  • Lluch Essence
    • Lluch Essence S.L.
      A family company dedicated to sales and distribution
      Flexibility, availability, price and quality.
      Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world.
      Email: Info
      Voice: 34 93 379 38 49
      Fax: 34 93 370 65 04
      Linkedin
      Product(s):
      ASCORBIC ACID
       
  • OQEMA
    • OQEMA
      With a focus on providing the highest level of service
      OQEMA has established itself at the forefront of the global chemical industry.
      The guiding principles of OQEMA have always been to establish long term relationships with customers and suppliers alike to build sustainable and profitable business for all parties. Through OQEMA’s business divisions the company tailors products and services to better support and service our customers requirements. This structure also allows the company to focus its marketing campaigns more effectively to certain industries. Over the last decade OQEMA has achieved strong growth as a result of the expansion of our business model. Going forward, the company will be expanding this business model into existing and new strategic territories.
      Email: Contact Us:
      US Email: Dean Matienzo
      Email: Sales
      US Email: Dean Matienzo - Sales Manager
      Voice: +44 1993 843081
      Fax: +44 1993 841261
      US Voice: +1 973 886 3778
      US Fax: +1 973 346 1106
      Linkedin
      Website
      Global Distribution
      Product(s):
      Vitamin C
       
  • Penta International
  • Sigma-Aldrich
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
      US Email: Sales
      Email: Technical Support
      Voice: 1-800-423-8616
      Fax: 1- 888-520-1075
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      Product(s):
      A0537 L-Ascorbic Acid >99.0%(T)
      SDS
       
  • United International
    • Qingdao Free Trade Zone United International Co Ltd
      Quality Products
      A partner in your supply chain solution.
      Qingdao Free Trade Zone United International Trade Co., Ltd.was founded in 1996, specializing in the production and import and export of food additives,flavor raw materials and pharmaceutical and chemical raw materials. The company has experienced R&D and business personnel,product quality, low price, efficient service and fast insight and grasp the latest market information.
      Email: Info
      Email: Sales
      Voice: +86-532-83893699
      Fax: +86-532-83893695
      Product(s):
      7178 Ascorbic Acid
       
  • Vigon International
    • Vigon International
      Passion for Simplicity
      Manufacturer and supplier of high quality flavor and fragrance ingredients.
      The growth and success of Vigon is due in large part to a unique corporate concept that Vigon has developed and established within the industry: Creative Partnerships. This partnership concept has been and continues to be the foundation and guiding principle for all of Vigon's activities.
      US Email: Sales
      US Voice: 570-476-6300
      US Fax: 570-476-1110
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      Products List: View
      Product(s):
      508696 ASCORBIC ACID
       
  • Zanos
    • Zanos Ltd.
      Distributor of Speciality Chemicals and Natural Ingredients
      Sourcing and supplying quality aroma chemicals and prestige natural ingredients for the flavour and fragrance industry.
      The flavour and fragrance industry's premier source for aroma chemicals and essential oils
      Zanos Ltd. is a B2B supplier of aroma chemicals, speciality chemicals, natural ingredients and vitamins to a diverse range of customers. In Autumn 2020, Stort Chemicals Limited completed their acquisition of Zanos Ltd. Combining our strengths, Stort and Zanos have boosted our respective portfolios of aroma chemicals, speciality chemicals and natural ingredients. With warehousing facilities across the UK, Rotterdam and Hamburg, Zanos is perfectly positioned to dispatch product throughout Europe.
      Email: Contact Zanos
      Email: Lisa Senior
      Voice: +44 (0) 1565 755899
      Fax: +44 (0) 1565 755799
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      Representation
      Products List: View
      Product(s):
      Vitamin C - Ascorbic acid
      Vitamin C DC 97% Ascorbic acid
       
Synonyms   Articles   Notes   Search
CAS Number: 50-81-7Picture of molecule3D/inchi
Other(deleted CASRN): 129940-97-2
ECHA EINECS - REACH Pre-Reg: 200-066-2
FDA UNII: PQ6CK8PD0R
Nikkaji Web: J2.301I
Beilstein Number: 0084272
MDL: MFCD00064328
XlogP3: -1.60 (est)
Molecular Weight: 176.12496000
Formula: C6 H8 O6
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome, Edge or firefox)
Category: cosmetic and flavor agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
182.3013, 182.8013 L-ascorbic acid View - review
EU SANCO Ascorbic acid View - review
GRN 769 Vitamin C (fruit and vegetable derived) View - notice PDF
JECFA Food Additive: Ascorbic Acid
GSFA Codex: Ascorbic acid, L- (300)
DG SANTE Food Additives: ascorbic acid
DG SANTE Food Contact Materials: ascorbic acid
FEMA Number: 2109 ascorbic acid
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):50-81-7 ; ASCORBIC ACID
FDA Regulation:
FDA PART 101 -- FOOD LABELING
Subpart A--General Provisions
Sec. 101.14 Health claims: general requirements.


FDA PART 101 -- FOOD LABELING
Subpart A--General Provisions
Sec. 101.9 Nutrition labeling of food.


FDA PART 107 -- INFANT FORMULA
Subpart D--Nutrient Requirements
Sec. 107.100 Nutrient specifications.


FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products
Sec. 137.105 Flour.


FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products
Sec. 137.200 Whole wheat flour.


FDA PART 145 -- CANNED FRUITS
Subpart B--Requirements for Specific Standardized Canned Fruits
Sec. 145.110 Canned applesauce.


FDA PART 145 -- CANNED FRUITS
Subpart B--Requirements for Specific Standardized Canned Fruits
Sec. 145.115 Canned apricots.


FDA PART 145 -- CANNED FRUITS
Subpart B--Requirements for Specific Standardized Canned Fruits
Sec. 145.135 Canned fruit cocktail.


FDA PART 145 -- CANNED FRUITS
Subpart B--Requirements for Specific Standardized Canned Fruits
Sec. 145.170 Canned peaches.


FDA PART 146 -- CANNED FRUIT JUICES
Subpart B--Requirements for Specific Standardized Canned Fruit Juices and Beverages
Sec. 146.185 Pineapple juice.


FDA PART 146 -- CANNED FRUIT JUICES
Subpart B--Requirements for Specific Standardized Canned Fruit Juices and Beverages
Sec. 146.187 Canned prune juice.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.141 Artificially sweetened fruit jelly.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.161 Artificially sweetened fruit preserves and jams.


FDA PART 155 -- CANNED VEGETABLES
Subpart B--Requirements for Specific Standardized Canned Vegetables
Sec. 155.200 Certain other canned vegetables.


FDA PART 155 -- CANNED VEGETABLES
Subpart B--Requirements for Specific Standardized Canned Vegetables
Sec. 155.201 Canned mushrooms.


FDA PART 161 -- FISH AND SHELLFISH
Subpart B--Requirements for Specific Standardized Fish and Shellfish
Sec. 161.175 Frozen raw breaded shrimp.


FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart C--Coatings, Films and Related Substances
Sec. 172.280 Terpene resin.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart D--Chemical Preservatives
Sec. 182.3013 Ascorbic acid.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart I--Nutrients
Sec. 182.8013 Ascorbic acid.
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: white to yellowish powder crystals (est)
Assay: 99.00 to 100.00 % 
Food Chemicals Codex Listed: Yes
Melting Point: 191.00 to  193.00 °C. @ 760.00 mm Hg
Boiling Point: 552.67 °C. @ 760.00 mm Hg (est)
Flash Point: > 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w): -1.850
Soluble in:
 water, 400000 mg/L @ 40C (exp)
Insoluble in:
 paraffin oil
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
Odor Strength: none
 
Odor Description:
at 100.00 %. 
very mild grassy
Luebke, William tgsc, (2007)
 
Odor and/or flavor descriptions from others (if found).
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antioxidants
buffering agents
fragrance
skin conditioning
Synonyms   Articles   Notes   Search   Top
Suppliers:
A.M.G.L.T.
Ascorbic Acid
Alfa Biotechnology
For experimental / research use only.
Vitamin C 98%
Allan Chemical
Ascorbic Acid
American International Chemical, LLC.
Vitamin C
AquaChemie
For experimental / research use only.
Ascorbic Acid
Atlantic Chemicals
Ascorbic Acid (Vitamin C)
AuNutra® Industries
Vitamin C
Balchem
Ascorbic Acid
VitaShure®
Flavor: characteristic
Vitashure is an extensive line of microencapsulated vitamins, minerals, amino acids, and bioactive substances, specifically designed for the supplementation and fortification industries.
BBFY Industrial
Ascorbic Acid
BOC Sciences
For experimental / research use only.
Vitamin C >98%
Odor: characteristic
Use: Ascorbic acid is a naturally occurring organic compound with antioxidant properties. antioxidant
Bristol Botanicals
Vitamin C powder
Charkit Chemical
ASCORBIC ACID
DSM Nutritional
Quali®-C (vitamin C)
ECSA Chemicals
L(+)ASCORBIC ACID RPE-ISO-FOR ANALYSIS, KG 1
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
ECSA Chemicals
VITAMIN C / ASCORBIC ACID BP/USP/PH.EUR
ECSA Chemicals
VITAMIN C / ASCORBIC ACID COATED
ExtraSynthese
For experimental / research use only.
L-(+)-Ascorbic Acid
Farbest-Tallman Foods
Ascorbic Acid 97% DC Starch Free
Flavor: tart
It is used in dietary supplement applications including hard shell capsules and tablets.
Farbest-Tallman Foods
Ascorbic Acid USP/FCC 80-100 Mesh
Flavor: tart
It is used in food, beverage and dietary supplement applications for a Vitamin C source and/or for its antioxidant capabilities. Some applications include nutrient enhanced beverages, powdered vitamin food blends and hard shell capsules.
Farbest-Tallman Foods
Ascorbic Acid USP/FCC Crystal
Flavor: tart
It is used in food, beverage and dietary supplement applications for a Vitamin C source and/or for its antioxidant capabilities. Some applications include nutrient enhanced beverages, powdered vitamin food blends and hard shell capsules.
Farbest-Tallman Foods
Ascorbic Acid USP/FCC Micropowder (325 Mesh)
Flavor: tart
It is used in food, beverage and dietary supplement applications for a Vitamin C source and/or for its antioxidant capabilities. Some applications include nutrient enhanced beverages, powdered vitamin food blends and hard shell capsules.
Farbest-Tallman Foods
Coated Ascorbic Acid 97.5%
Flavor: tart
It is used in food applications where ascorbic acid would be susceptible to degradation.
Foodchem International
Ascorbic Acid
George Uhe Company
Ascorbic Acid
Glentham Life Sciences
L-(+)-Ascorbic acid, 99.5%, BP, Ph. Eur., USP grade
Glentham Life Sciences
L-(+)-Ascorbic acid
Graham Chemical
Ascorbic Acid
Indis NV
For experimental / research use only.
Ascorbic Acid
Kraft Chemical
Ascorbic Acid
Lluch Essence
ASCORBIC ACID
Maypro Industries
Ascorbic Acid DC97
Northwestern Extract
Ascorbic Acid FCC
OQEMA
Vitamin C
Penta International
ASCORBIC ACID CRYSTAL
Penta International
ASCORBIC ACID NATURAL USP/FCC CRYSTAL
Penta International
ASCORBIC ACID NATURAL USP/FCC POWDER
Penta International
ASCORBIC ACID POWDER
Penta International
ASCORBIC ACID USP
Prinova
Ascorbic Acid
Qingdao Dacon Trading
Vitamin C
Sigma-Aldrich
L-Ascorbic acid, FCC, FG
Certified Food Grade Products
Silver Fern Chemical
Ascorbic Acid
Odor: characteristic
Use: Ascorbic Acid’s most common application is a food additive. This vitamin acts as an antioxidant as well as a preservative. Other common uses include removing metal stains from fiberglass, plastic manufacturing, and as a component to iodine water purifying.
Sinofi Food Ingredients
Ascorbic Acid
Odor: characteristic
Use: Antioxidants, Nutrient, Dietary Supplement, Color Fixing Agent, Flavoring Agent, Preservative, Bacon, Chewing Gum, Dairy Products, Confections, Baking Food, Yogurt, Soft Drink, Beverage Powder, Fruit Juice, Puddings, Ice Cream, Fruit Sauces, Sauage, Meats, Cosmetics, Feed, Pharmaceutical.
Sinofi Food Ingredients
Vitamin C
Odor: characteristic
Use: Antioxidants, Nutrient, Dietary Supplement, Soft Drink, Beverage Powder, Fruit Juice, Puddings, Ice Cream, Fruit Sauces, Chewing Gum, Dairy Products, Confections, Baking Food, Yogurt, Sauage, Color Fixing Agent, Flavoring Agent, Preservative, Bacon, Meats, Cosmetics, Feed, Pharmaceutical.
TCI AMERICA
For experimental / research use only.
L-Ascorbic Acid >99.0%(T)
Tianjin Talent Chemical
Ascorbic Acid 30-300mesh Crystal Powder
Tianjin Talent Chemical
Ascorbic Acid 80/100/200/300mesh fine powder
Tianjin Talent Chemical
Ascorbic Acid DC Granule 90,93,95,97
Tianjin Talent Chemical
Ascorbic Acid DC Granule 90SF,93SF,95SF,97SF
Tianjin Talent Chemical
Coated Ascorbic Acid
United International
Ascorbic Acid
Vigon International
ASCORBIC ACID
WILD Flavors
Vitamin C
Flavor: taste
Through WILD’s agreement with Cognis® Nutrition and Health, natural Vitamin E is now available to customers. Vitamins A, C and E show antioxidant activity. They all reduce oxidative stress in the body by neutralizing free radicals.
Zanos
Vitamin C - Ascorbic acid
Zanos
Vitamin C DC 97% Ascorbic acid
Zhong Ya Chemical
Ascorbic Acid
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  11900 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 131, 1976.

intravenous-rat LD50  > 4000 mg/kg
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 131, 1976.

oral-mouse LD50  3367 mg/kg
National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986

intravenous-mouse LD50  518 mg/kg
Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 269, 1970.

intraperitoneal-mouse LD50  643 mg/kg
Progress in Mutation Research. Vol. 1, Pg. 682, 1981.

intravenous-man TDLo  2300 mg/kg/2D
BLOOD: OXIDANT RELATED (GPD DEFICIENT) ANEMIA
Annals of Internal Medicine. Vol. 82, Pg. 810, 1975.

Dermal Toxicity:
subcutaneous-rat LD50 > 10000 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 131, 1976.

Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: cosmetic and flavor agents
Recommendation for ascorbic acid usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: 1.00000500.00000
beverages(nonalcoholic): -130.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: 0.80000250.00000
fruit ices: 0.80000250.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: 4.000006000.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: 0.49000470.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: 280.00000380.00000
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
European Food Safety Authority (EFSA) reference(s):
Scientific Report of EFSA on the risk assessment of salts of authorised acids, phenols or alcohols for use in food contact materials [1]
View page or View pdf
Scientific Opinion on the safety and efficacy of vitamin C (ascorbic acid, sodium ascorbate, calcium ascorbate, ascorbyl palmitate, sodium calcium ascorbyl phosphate and sodium ascorbyl phosphate) as a feed additive for all animal species based on a dossier submitted by DSM Nutritional Products Ltd
View page or View pdf
Scientific Opinion on the safety and efficacy of vitamin C (ascorbic acid and sodium calcium ascorbyl phosphate) as a feed additive for all animal species based on a dossier submitted by VITAC EEIG
View page or View pdf
Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid
View page or View pdf
Scientific Opinion on Dietary Reference Values for vitamin C
View page or View pdf
Outcome of a public consultation on the Draft Scientific Opinion of the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) on Dietary Reference Values for vitamin C
View page or View pdf
Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006
View page or View pdf
Scientific Opinion on the re-evaluation of ascorbic acid (E 300), sodium ascorbate (E 301) and calcium ascorbate (E 302) as food additives
View page or View pdf
Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006
View page or View pdf
Pesticide active substances that do not require a review of the existing maximum residue levels under Article 12 of Regulation (EC) No 396/2005
View page or View pdf
Vitamin C and protection of DNA, proteins and lipids from oxidative damage: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006
View page or View pdf
Outcome of the consultation with Member States, the applicant and EFSA on the pesticide risk assessment for L-ascorbic acid in light of confirmatory data
View page or View pdf
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
NIOSH International Chemical Safety Cards: search
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EPA Substance Registry Services (TSCA): 50-81-7
EPA ACToR: Toxicology Data
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Laboratory Chemical Safety Summary : 54670067
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2(5H)-furanone
Chemidplus: 0000050817
EPA/NOAA CAMEO: hazardous materials
RTECS: 50-81-7
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References:
 (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2(5H)-furanone
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 50-81-7
Pubchem (cid): 54670067
Pubchem (sid): 134971787
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
FDA Indirect Additives used in Food Contact Substances:View
CHEBI: View
CHEMBL: View
Golm Metabolome Database: Search
Metabolomics Database: Search
KEGG (GenomeNet): C00072
HMDB (The Human Metabolome Database): HMDB00044
FooDB: FDB001224
Export Tariff Code: 2936.27.0000
FDA Listing of Food Additive Status: View
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
EFSA Update of results on the monitoring of furan levels in food: Read Report
EFSA Previous report: Results on the monitoring of furan levels in food: Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food: Read Report
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 antioxidants 
 buffering agents 
 skin conditioning 
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Occurrence (nature, food, other): note
 allspice fruit
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 allspice leaf
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 almond seed
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 anise seed
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 apple custard apple fruit
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 apple custard apple fruit
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 apple fruit
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 apricot fruit
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 arrowroot root
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 artichoke jerusalem artichoke tuber
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 asparagus root
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 asparagus shoot
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 avocado fruit
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 banana fruit
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 banana hull husk
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 barley seed
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 barley stem
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 basil leaf
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 basswood leaf
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 bean adzuki bean seed
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 bean asparagus bean fruit
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 bean asparagus bean seed
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 bean banner bean fruit
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 bean banner bean seed
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 bean black bean fruit
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 bean black bean leaf
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 bean black bean seed
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 bean black bean sprout
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 bean butter bean seed
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 bean butter bean sprout
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 bean fava bean fruit
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 bean fava bean seed
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 bean lima bean seed
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 bean mat bean seed
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 bean mung bean seed
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 bean mung bean sprout
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 bean scarlet runner bean fruit
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 bean scarlet runner bean seed
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 bean winged bean fruit
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 bean winged bean seed
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 bean yam bean plant
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 beet leaf
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 beet root
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 bilberry fruit
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 black gram seed
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 black gram sprout
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 blueberry fruit
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 borage leaf
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 borage shoot
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 brazil nut
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 breadfruit fruit
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 breadfruit seed
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 breadnut fruit
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 broadbean seed
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 broccoli asparagus broccoli leaf
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 brussel sprout leaf
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 buckthorn sea buckthorn
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 buckthorn sea buckthorn fruit
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 buckthorn sea buckthorn leaf
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 buckwheat seed
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 burdock root
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 butterbur plant
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 cabbage leaf
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 cacao bean
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 cacao fruit
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 cantaloupe fruit
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 caper flower
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 caper fruit
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 caper leaf
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 caper seed
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 carrot root
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 cashew fruit
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 cashew leaf
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 cashew nut
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 cassava leaf
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 cassava root
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 cassia bark
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 cayenne fruit
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 celery fruit
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 celery plant
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 celery seed
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 celery shoot
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 chamomile garden chamomile flower
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 chamomile sweet false chamomile plant
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 chayote fruit
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 chayote shoot
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 cherimoya fruit
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 cherry brazilian cherry fruit
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 cherry sour cherry fruit
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 chestnut water chestnut tuber
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 chickpea seed
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 chicory leaf
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 chicory root
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 chive leaf
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 chrysanthemum coronarium leaf
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 chrysanthemum edible chrysanthemum bud
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 chrysanthemum edible chrysanthemum leaf
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 cinnamon ceylon cinnamon bark
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 clove bark
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 coconut seed
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 coriander fruit
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 coriander leaf
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 coriander seed
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 corn seed
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 corn silk
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 cranberry fruit
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 cress garden cress leaf
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 cumin seed
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 cumin tissue culture
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 currant black currant fruit
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 currant black currant leaf
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 currant red currant fruit
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 dandelion leaf
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 dandelion root
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 date palm fruit
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 dill plant
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 dill seed
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 durian fruit
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 eggplant fruit
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 eggplant leaf
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 elder black elder fruit
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 elder black elder leaf
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 endive leaf
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 fennel leaf
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 fennel plant
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 fennel seed
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 fenugreek leaf
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 fenugreek seed
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 fenugreek shoot
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 fig fruit
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 fig leaf
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 garlic bulb
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 garlic flower
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 garlic leaf
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 garlic root
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 garlic shoot
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 ginger root
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 ginkgo biloba fruit
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 ginkgo biloba leaf
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 ginkgo biloba seed
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 gooseberry cape gooseberry fruit
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 gooseberry fruit
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 goosefoot plant
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 gourd calabash gourd fruit
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 gourd calabash gourd leaf
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 gourd white gourd fruit
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 grape fruit
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 grape leaf
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 grape stem
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 guava fruit
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 guava pineapple guava fruit
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 guava seed
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 guava strawberry guava fruit
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 hazelnut leaf
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 hazelnut nut
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 horseradish leaf
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 horseradish plant
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 horseradish root
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 irish moss plant
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 jackfruit fruit
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 jambul fruit
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 kiwi fruit
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 kohlrabi stem
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 leek wild leek flower
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 leek wild leek leaf
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 leek wild leek root
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 lemon fruit
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 lemon fruit juice
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 lentil seed
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 lentil sprout
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 lettuce leaf
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 lime fruit
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 loquat fruit
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 lotus indian lotus rhizome
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 lotus indian lotus seed
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 luffa fruit
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 luffa leaf
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 macadamia nut
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 mallow jew's mallow leaf
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 mamey fruit
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 mandarin fruit
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 mango fruit
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 mango leaf
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 mangosteen fruit
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 mangosteen purple mangosteen fruit
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 marango fruit
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 marango leaf
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 marango shoot
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 marjoram plant
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 melon bitter melon fruit
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 melon bitter melon leaf
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 mugwort leaf
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 mustard white mustard plant
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 nance fruit
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 oat plant
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 okra fruit
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 onion bulb
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 onion leaf
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 orange fruit
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 oregano plant
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 papaya fruit
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 papaya leaf
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 parsley fruit
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 parsley leaf
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 parsley plant
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 parsley seed
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 parsley shoot
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 parsnip root
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 passion fruit
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 passion fruit fruit
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 pea black-eyed pea seed
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 pea black-eyed pea shoot
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 pea fruit
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 pea pigeon pea fruit
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 pea pigeon pea seed
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 pea seed
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 pea sprout
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 peach fruit
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 peanut leaf
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 peanut nut
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 pear fruit
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 pepper bell pepper fruit
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 pepper black pepper fruit
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 pepper black pepper seed
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 peppermint leaf
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 persimmon american persimmon fruit
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 pigweed leaf
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 pine pinyon pine seed
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 pineapple fruit
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 plum fruit
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 plum malabar plum fruit
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 plum sap
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 pokeweed shoot
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 pomegranate fruit
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 pomegranate fruit juice
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 poppy opium poppy fruit
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 poppy opium poppy seed
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 poppy opium poppy tissue culture
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 potato sweet potato leaf
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 potato sweet potato root
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 potato tuber
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 purslane herb
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 purslane plant
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 quince fruit
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 radish fruit
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 radish leaf
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 radish root
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 raspberry red raspberry
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 raspberry red raspberry fruit
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 raspberry red raspberry leaf
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 raspberry red raspberry seed
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 rhubarb leaf
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 rhubarb plant
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 rice seed
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 rose hips fruit
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 roselle flower
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 roselle fruit
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 rosemary leaf
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 rue leaf
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 safflower flower
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 safflower seed
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 sage leaf
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 salsify root
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 sapodilla fruit
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 sorrel garden sorrel leaf
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 sorrel west african sorrel leaf
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 soursop fruit
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 soybean fruit
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 soybean seed
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 soybean sprout
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 spearmint leaf
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 spinach fruit juice
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 spinach indian spinach leaf
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 spinach leaf
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 spinach plant
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 spinach sea spinach leaf
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 spinach water spinach leaf
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 spirulina plant
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 squash summer squash fruit
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 star fruit fruit
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 strawberry guava fruit
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 tamarind flower
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 tamarind fruit
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 tamarind leaf
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 tamarind seed
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 taro leaf
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 taro root
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 tarragon leaf
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 tea leaf
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 thyme leaf
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 tomatillo fruit
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 tomato fruit
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 turmeric plant
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 turmeric rhizome
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 turnip indian turnip root
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 walnut black walnut fruit
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 walnut black walnut nut
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 walnut black walnut pericarp
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 walnut english walnut fruit
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 walnut english walnut leaf
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 walnut english walnut nut
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 watercress herb
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 watercress shoot
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 watermelon fruit
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 wheat seed
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 wormwood wild wormwood leaf
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 yam mountain yam root
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 yam wild yam root
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Synonyms   Articles   Notes   Search   Top
Synonyms:
L-(+)-ascorbic acid
laevo-(+)-ascorbic acid
 ascorbic acid (vitamin C)
 ascorbic acid (vitamin C) 97 granular
 ascorbic acid (vitamin C) USP
 ascorbic acid 97% DC starch free
 ascorbic acid crystals FCC
 ascorbic acid FCC
L-ascorbic acid FCC
 ascorbic acid USP
 ascorbic acid USP natural
 ascorbic acid USP powder FCC
 ascorbic acid USP/FCC 80-100 mesh
 ascorbic acid USP/FCC crystal
 ascorbic acid USP/FCC micropowder (325 mesh)
 ascorbicap
 calscorbate
 catavin C
 cetebe
 coated ascorbic acid 97.5%
(5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2(5H)-furanone
(5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one
(2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one
3-keto-L-gulofuranolactone
3-keto-laevo-gulofuranolactone
3-oxo-L-gulofuranolactone
3-oxo-laevo-gulofuranolactone
 quali-C (vitamin C)
 vitamin C
Synonyms   Articles   Notes   Search   Top
Articles:
Info: EVALUATION OF CERTAIN FOOD ADDITIVES AND CONTAMINANTS
PubMed: Influence of antioxidant compounds, total sugar contents and genetic background on the chilling injury susceptibility of a non-melting peach [Prunus persica (L.) Batsch] progeny.
PubMed: Effects of Dimethyl Dicarbonate (DMDC) on the Fermentation of Litchi Juice by Lactobacillus Casei as an Alternative of Heat Treatment.
PubMed: Encapsulation altered starch digestion: toward developing starch-based delivery systems.
PubMed: Antioxidant action of ganghwayakssuk (Artemisia princeps Pamp.) in combination with ascorbic acid to increase the shelf life in raw and deep fried chicken nuggets.
PubMed: Differences in particle characteristics and oxidized flavor as affected by heat-related processes of milk powder.
PubMed: Factors influencing the formation of medicinal off-flavor from ascorbic acid and α,β-unsaturated aldehydes.
PubMed: Study on mitigation of acrylamide formation in cookies by 5 antioxidants.
PubMed: Elucidating the formation pathway of the off-flavor compound 6-propylbenzofuran-7-ol.
PubMed: The effect of vitamin C administration on monosodium glutamate induced liver injury. An experimental study.
PubMed: Juice blends--a way of utilization of under-utilized fruits, vegetables, and spices: a review.
PubMed: Changes in quality, liking, and purchase intent of irradiated fresh-cut spinach during storage.
PubMed: Identification of the medicinal off-flavor compound formed from ascorbic acid and (E)-hex-2-enal.
PubMed: Vacuum frying as a route to produce novel snacks with desired quality attributes according to new health trends.
PubMed: Effect of cassava starch coating on quality and shelf life of fresh-cut pineapple (Ananas comosus L. Merril cv "Pérola").
PubMed: Inhibition of citral degradation by oil-in-water nanoemulsions combined with antioxidants.
PubMed: Fermented vegetables containing benzoic and ascorbic acids as additives: benzene formation during storage and impact of additives on quality parameters.
PubMed: Effect of grape seed extract on oxidative, color and sensory stability of a pre-cooked, frozen, re-heated beef sausage model system.
PubMed: Comparative antioxidant activity study of some commonly used spices in Bangladesh.
PubMed: Fruit and soil quality of organic and conventional strawberry agroecosystems.
PubMed: Quality characterization of celery (Apium graveolens L.) by plant zones and two harvest dates.
PubMed: The impact of antioxidant addition on flavor of cheddar and mozzarella whey and cheddar whey protein concentrate.
PubMed: The role of ascorbic acid and monosodium glutamate in thymocyte apoptosis.
PubMed: Tastier and healthier alternatives to French fries.
PubMed: Evaluation of natural antimicrobials on typical meat spoilage bacteria in vitro and in vacuum-packed pork meat.
PubMed: Identification of a sotolon pathway in dry white wines.
PubMed: A diet based on high-heat-treated foods promotes risk factors for diabetes mellitus and cardiovascular diseases.
PubMed: Effect of liberibacter infection (huanglongbing disease) of citrus on orange fruit physiology and fruit/fruit juice quality: chemical and physical analyses.
PubMed: Effect of rosemary, echinacea, green tea extracts and ascorbic acid on broiler meat quality.
PubMed: Influence of thermal and dense-phase carbon dioxide pasteurization on physicochemical properties and flavor compounds in Hami melon juice.
PubMed: Ascorbic acid modulates monosodium glutamate induced cytotoxicity in rat thymus.
PubMed: Effect of tenderizers combined with organic acids on Escherichia coli O157:H7 thermal resistance in non-intact beef.
PubMed: Variability for free sugars and organic acids in Capsicum chinense.
PubMed: The role of oxylipins and antioxidants on off-flavor precursor formation during potato flake processing.
PubMed: Antioxidants in bakery products: a review.
PubMed: Analysis of expressed sequence tags from Actinidia: applications of a cross species EST database for gene discovery in the areas of flavor, health, color and ripening.
PubMed: Qualitative and nutritional differences in processing tomatoes grown under commercial organic and conventional production systems.
PubMed: Relationship between physical properties and sensory attributes of carbonated beverages.
PubMed: Fruits of the actinidia genus.
PubMed: Antioxidant property of Decalepis hamiltonii Wight & Arn.
PubMed: Enhancing the retention of phytochemicals and organoleptic attributes in muscadine grape juice through a combined approach between dense phase CO2 processing and copigmentation.
PubMed: Monosodium glutamate-induced oxidative damage and genotoxicity in the rat: modulatory role of vitamin C, vitamin E and quercetin.
PubMed: Interactions between mitochondrial lipid oxidation and oxymyoglobin oxidation and the effects of vitamin E.
PubMed: Stability and sensory shelf life of orange juice pasteurized by continuous ohmic heating.
PubMed: Effect of ultrahigh-temperature continuous ohmic heating treatment on fresh orange juice.
PubMed: Interaction of soluble peptides and proteins from skeletal muscle with volatile compounds in model systems as affected by curing agents.
PubMed: Effect of antioxidant (alpha-tocopherol and ascorbic acid) fortification on light-induced flavor of milk.
PubMed: [Microbiological and physicochemical evaluation of pasteurized nectar elaborated with tree tomato (Cyphomandra betaceae Sendth)pulp].
PubMed: Commercial scale pulsed electric field processing of tomato juice.
PubMed: Effects of processing treatment and sorbate addition on the flavor characteristics of apple cider.
PubMed: [Stability of anthocyanins in pasteurized juice of blackberry ((Rubus glaucus benth].
PubMed: Effects of vascular infusion with a solution of saccharides; sodium chloride; phosphates; and vitamins C, E, or both on carcass traits, Warner-Bratzler shear force, and palatability traits of steaks and ground beef.
PubMed: Flavor release in the presence of melanoidins prepared from L-(+)-ascorbic acid and amino acids.
PubMed: Degradation of the coffee flavor compound furfuryl mercaptan in model Fenton-type reaction systems.
PubMed: Relationships among dietary roasted soybeans, milk components, and spontaneous oxidized flavor of milk.
PubMed: Effect of dietary vitamin C on concentrations of ascorbic acid in plasma and milk.
PubMed: Postharvest induction modeling method using UV irradiation pulses for obtaining resveratrol-enriched table grapes: a new "functional" fruit?
PubMed: Influence of dietary fat source, alpha-tocopherol, and ascorbic acid supplementation on sensory quality of dark chicken meat.
PubMed: Flavor, color, and vitamin C retention of pulsed electric field processed orange juice in different packaging materials.
PubMed: Effects of pulsed electric fields on the quality of orange juice and comparison with heat pasteurization.
PubMed: [Effect of 3 storage temperatures on the quality of kiwi fruit pulp concentrated at a reduced pressure].
PubMed: Antioxidant activity of selected Indian spices.
PubMed: Off-flavor compounds in wine and other food products formed by enzymatical, physical, and chemical degradation of tryptophan and its metabolites.
PubMed: Effect of ascorbic acid on iron release from the emulsifier interface and on the oxidative flavor deterioration in fish oil enriched mayonnaise.
PubMed: 3-Hydroxy-4,5-dimethyl-2(5H)-furanone (Sotolon) causing an off-flavor: elucidation of its formation pathways during storage of citrus soft drinks.
PubMed: Preventing iron deficiency through food fortification.
PubMed: Chemical composition and organoleptic evaluation of juice from steamed cashew apple blended with orange juice.
PubMed: Physico-chemical and sensory properties of formulated syrup from black plum (Vitex doniana) fruit.
PubMed: [Chemical and microbiological studies of microwave-treated milk].
PubMed: NTP Carcinogenesis Bioassay of L-Ascorbic Acid (Vitamin C) (CAS No. 50-81-7) in F344/N Rats and B6C3F1 Mice (Feed Study).
PubMed: [Effect of storage on the levels of ascorbic acid and beta-carotene in freeze dried red guava (Psidium guayava L.)].
PubMed: Behavioral control of medicine compliance.
PubMed: Fortification of hamburger with calcium, vitamin A, and ascorbic acid.
PubMed: [Sensory and chemical changes of dried foods under the influence of extreme storage conditions. 4. Flavor compounds (authors transl)].
PubMed: INFLUENCE OF HOMOGENIZATION, COPPER, AND ASCORBIC ACID ON FLAVOR IN MILK.
PubMed: Flavor, color, and ascorbic acid retention; comparison of electronic vs. conventional cooking of vegetables.
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