Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless to cream amber crystalline powder (est) |
Assay: | 97.00 to 100.00 %
|
Food Chemicals Codex Listed: | No |
Specific Gravity: | 1.12700 @ 25.00 °C.
|
Melting Point: | 38.00 to 40.00 °C. @ 760.00 mm Hg
|
Boiling Point: | 238.00 °C. @ 760.00 mm Hg
|
Boiling Point: | 122.00 °C. @ 20.00 mm Hg
|
Vapor Pressure: | 0.062000 mmHg @ 25.00 °C. (est) |
Flash Point: | 244.00 °F. TCC ( 117.78 °C. )
|
logP (o/w): | 1.720 |
Soluble in: |
| alcohol | | propylene glycol | | water, 2951 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Similar Items: note |
homoanisaldehyde |
meta-anisaldehyde |
para-anisaldehyde |
Organoleptic Properties:
|
Odor Type: anisic |
|
Odor Strength: | medium , recommend smelling in a 10.00 % solution or less |
|
Substantivity: | 24 hour(s) at 10.00 % in propylene glycol |
|
| sweet powdery hawthorn guaiacol vanilla hawthorn almond |
Odor Description: at 10.00 % in propylene glycol. | sweet powdery hawthorn guaiacol vanilla acetophenone almond Luebke, William tgsc, (1985) |
|
|
Flavor Type: anisic |
|
| sweet powdery guaiacol musty vanilla floral almond |
Taste Description: at 50.00 ppm in water. | sweet powdery guaiacol musty vanilla floral almond Luebke, William tgsc, (2006) |
|
Odor and/or flavor descriptions from others (if found). |
|
|
Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xi - Irritant |
R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
|
|
Hazards identification |
|
Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
|
Pictogram | |
|
Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Human Experience: |
4 % solution: no irritation or sensitization. |
Oral/Parenteral Toxicity: |
oral-rat LD50 2500 mg/kg (Moreno, 1977ac)
gavage-mouse LD50 [sex: M] 2.40 ml/kg (Field, 1979b)
gavage-rat LD50 [sex: M] 2.40-2.80 ml/kg (Field, 1979b)
oral-mouse LD50 2400 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE National Technical Information Service. Vol. OTS0533625
oral-rat LD50 2500 mg/kg Food and Cosmetics Toxicology. Vol. 17, Pg. 855, 1979.
|
Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 17, Pg. 855, 1979.
|
Inhalation Toxicity: |
Not determined
|
Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for ortho-anisaldehyde usage levels up to: | | 2.0000 % in the fragrance concentrate.
|
|
Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.16 (μg/capita/day) |
Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 1400 (μg/person/day) |
Threshold of Concern: | 1800 (μg/person/day) |
Structure Class: | I |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 22 |
Click here to view publication 22 |
| average usual ppm | average maximum ppm |
baked goods: | 10.00000 | 50.00000 |
beverages(nonalcoholic): | 1.00000 | 10.00000 |
beverages(alcoholic): | 3.00000 | 30.00000 |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | 30.00000 | 50.00000 |
condiments / relishes: | - | - |
confectionery froastings: | 5.00000 | 20.00000 |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | 5.00000 | 20.00000 |
fruit ices: | 1.00000 | 10.00000 |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | 10.00000 | 20.00000 |
imitation dairy: | - | - |
instant coffee / tea: | 5.00000 | 50.00000 |
jams / jellies: | 1.00000 | 10.00000 |
meat products: | - | - |
milk products: | 5.00000 | 20.00000 |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | 5.00000 | 20.00000 |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
|
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). |
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. |
| average usage mg/kg | maximum usage mg/kg |
Dairy products, excluding products of category 02.0 (01.0): | 3.00000 | 15.00000 |
Fats and oils, and fat emulsions (type water-in-oil) (02.0): | 2.00000 | 10.00000 |
Edible ices, including sherbet and sorbet (03.0): | 3.00000 | 15.00000 |
Processed fruit (04.1): | 2.00000 | 10.00000 |
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | - | - |
Confectionery (05.0): | 5.00000 | 25.00000 |
Chewing gum (05.0): | - | - |
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 2.00000 | 10.00000 |
Bakery wares (07.0): | - | - |
Meat and meat products, including poultry and game (08.0): | 1.00000 | 5.00000 |
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | 1.00000 | 5.00000 |
Eggs and egg products (10.0): | - | - |
Sweeteners, including honey (11.0): | - | - |
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | 2.00000 | 10.00000 |
Foodstuffs intended for particular nutritional uses (13.0): | 3.00000 | 15.00000 |
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | 2.00000 | 10.00000 |
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | 5.00000 | 25.00000 |
Ready-to-eat savouries (15.0): | 5.00000 | 25.00000 |
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 2.00000 | 10.00000 |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23 View page or View pdf |
Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 54 (FGE.54)[1] - Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20 (2005) - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf |
Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23 View page or View pdf |
Flavouring Group Evaluation 54, Revision 1 (FGE.54Rev1): Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20Rev1 (2009) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 4 (FGE.20Rev4): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 135-02-4 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 8658 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 2 |
| 2-methoxybenzaldehyde |
Chemidplus: | 0000135024 |
RTECS: | BZ2610000 for cas# 135-02-4 |
References:
Other Information:
Potential Blenders and core components note
|
For Odor |
acidic |
| cyclohexyl acetic acid | FL/FR |
amber |
| ambrette seed oil | FL/FR |
anisic |
para- | acetanisole | FL/FR |
ortho- | acetanisole | FL/FR |
para- | anisaldehyde | FL/FR |
balsamic |
iso | amyl benzoate | FL/FR |
| amyris wood oil | FL/FR |
siam | benzoin resinoid | FL/FR |
| benzophenone | FR |
| benzyl cinnamate | FL/FR |
iso | bornyl acetate | FL/FR |
iso | butyl benzoate | FL/FR |
| cinnamyl alcohol | FL/FR |
| ethyl cinnamate | FL/FR |
| fir balsam absolute | FR |
| peru balsam oil | FL/FR |
3- | phenyl propyl alcohol | FL/FR |
| styrax resinoid (liquidambar styraciflua) | FL/FR |
berry |
| raspberry ketone | FL/FR |
buttery |
| acetoin | FL/FR |
caramellic |
| ethyl maltol | FL/FR |
chocolate |
iso | amyl phenyl acetate | FL/FR |
| cocoa oleoresin | FL/FR |
| cocoa pentenal | FL/FR |
citrus |
sweet | orange peel oil c.p. brazil | FL/FR |
creamy |
para- | vanillic acid | FL/FR |
floral |
| acetophenone | FL/FR |
alpha- | amyl cinnamaldehyde | FL/FR |
iso | amyl salicylate | FL/FR |
para- | anisaldehyde / methyl anthranilate schiff's base | FR |
para- | anisaldehyde dimethyl acetal | FR |
para- | anisyl acetaldehyde | FL/FR |
para- | anisyl nitrile | FR |
| anisyl propanal / methyl anthranilate schiff's base | FR |
| citronellol | FL/FR |
| dihydrojasmone | FL/FR |
| dimethyl alpha-ionone | FR |
| dimethyl anthranilate | FL/FR |
| dimethyl benzyl carbinyl butyrate | FL/FR |
| earthy indane | FR |
para- | ethyl acetophenone | FL/FR |
| ethyl phenyl acetate | FL/FR |
| floral pyranol | FR |
| geraniol | FL/FR |
| geranyl phenyl acetate | FL/FR |
| hawthorn carbinol | FL/FR |
| heliotropin | FL/FR |
| heliotropyl acetate | FL/FR |
| heliotropyl acetone | FL/FR |
alpha- | hexyl cinnamaldehyde | FL/FR |
| hydroxycitronellal | FL/FR |
alpha- | irone | FL/FR |
| lilyall | FR |
ortho- | methyl acetophenone | FL/FR |
para- | methyl acetophenone | FL/FR |
beta-iso | methyl ionone | FL/FR |
alpha-iso | methyl ionone (50% min.) | FL/FR |
alpha-iso | methyl ionone (90% min.) | FL/FR |
| methyl ionyl acetate | FL/FR |
| nonanol | FL/FR |
| ocean propanal | FL/FR |
| orris rhizome resinoid (iris pallida) | FL/FR |
| phenethyl alcohol | FL/FR |
| phenethyl phenyl acetate | FL/FR |
| propiophenone | FL/FR |
iso | propyl anthranilate | FL/FR |
iso | propyl phenyl acetate | FL/FR |
| rhodinol | FL/FR |
| rhodinyl phenyl acetate | FL/FR |
| rose butanoate | FL/FR |
(E)-2,5,9- | trimethyl-4,9-decadien-1-al | FR |
fruity |
| acetyl methyl anthranilate | FL/FR |
| cherry oxyacetate | FL/FR |
| ethyl methyl-para-tolyl glycidate | FL/FR |
| peach pivalate | FR |
| tolualdehydes (mixed o,m,p) | FL/FR |
gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
green |
para- | dimethyl hydroquinone | FL/FR |
para- | methyl hydratropaldehyde | FL/FR |
| phenoxyethyl isobutyrate | FL/FR |
hay |
| beeswax absolute | FL/FR |
herbal |
| apium graveolens seed oil india | FL/FR |
licorice |
(E)- | anethol | FL/FR |
minty |
| ethyl salicylate | FL/FR |
mossy |
| veramoss (IFF) | FR |
musk |
| cyclohexadecanone | FR |
| ethylene brassylate | FL/FR |
| exaltone (Firmenich) | FR |
dextro,laevo- | muscone | FL/FR |
| musk amberol | FR |
| musk indane | FR |
| musk tetralin | FL/FR |
omega- | pentadecalactone | FL/FR |
musty |
| cocoa butenal | FL/FR |
naphthyl |
para- | methyl anisole | FL/FR |
beta- | naphthyl ethyl ether | FL/FR |
beta- | naphthyl methyl ether | FL/FR |
nutty |
2,3,5- | trimethyl pyrazine | FL/FR |
powdery |
para- | anisyl acetate | FL/FR |
para- | anisyl alcohol | FL/FR |
alpha- | methyl ionone | FL/FR |
smoky |
| propyl paraben | CS |
| cassia bark oil china | FL/FR |
| cuminaldehyde | FL/FR |
iso | eugenyl acetate | FL/FR |
alpha- | methyl cinnamaldehyde | FL/FR |
| methyl isoeugenol | FL/FR |
sweet |
| tonka bean absolute replacer | FR |
terpenic |
alpha- | terpineol | FL/FR |
tonka |
| coumarin | FR |
| flouve absolute | FR |
| mint lactone | FL/FR |
| tonka bean absolute | FR |
vanilla |
| ethyl vanillin | FL/FR |
| heliotropyl alcohol | FL/FR |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
| vanillyl acetate | FL/FR |
| vanillylidene acetone | FL/FR |
woody |
| amber formate | FR |
| guaiacwood oil | FL/FR |
| patchouli ethanone | FR |
| santall | FR |
(+)-alpha- | santalyl acetate | FL/FR |
| timber propanol | FR |
| vetiveryl acetate | FL/FR |
| woody acetate | FR |
| woody epoxide | FR |
|
For Flavor |
|
No flavor group found for these |
para- | anisyl acetaldehyde | FL/FR |
para- | ethyl acetophenone | FL/FR |
| heliotropyl alcohol | FL/FR |
beta-iso | methyl ionone | FL/FR |
iso | propyl anthranilate | FL/FR |
(+)-alpha- | santalyl acetate | FL/FR |
| vetiveryl acetate | FL/FR |
|
4'- | hydroxyacetophenone | FL |
amber |
| ambrette seed oil | FL/FR |
| musk tetralin | FL/FR |
anise |
(E)- | anethol | FL/FR |
anisic |
para- | acetanisole | FL/FR |
ortho- | methyl acetophenone | FL/FR |
balsamic |
siam | benzoin resinoid | FL/FR |
| ethyl cinnamate | FL/FR |
| peru balsam oil | FL/FR |
| styrax resinoid (liquidambar styraciflua) | FL/FR |
| vanillylidene acetone | FL/FR |
berry |
| heliotropyl acetone | FL/FR |
| raspberry ketone | FL/FR |
brown |
| beeswax absolute | FL/FR |
caramellic |
| ethyl maltol | FL/FR |
cherry |
| heliotropin | FL/FR |
chocolate |
| cocoa oleoresin | FL/FR |
citrus |
sweet | orange peel oil c.p. brazil | FL/FR |
alpha- | terpineol | FL/FR |
coconut |
6- | methyl coumarin | FL |
creamy |
| acetoin | FL/FR |
para- | anisaldehyde | FL/FR |
para- | methyl acetophenone | FL/FR |
| mint lactone | FL/FR |
gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
para- | vanillic acid | FL/FR |
floral |
iso | amyl phenyl acetate | FL/FR |
| citronellol | FL/FR |
| cocoa pentenal | FL/FR |
| dihydrojasmone | FL/FR |
| dimethyl benzyl carbinyl butyrate | FL/FR |
| geraniol | FL/FR |
| geranyl phenyl acetate | FL/FR |
| heliotropyl acetate | FL/FR |
alpha-iso | methyl ionone (50% min.) | FL/FR |
alpha-iso | methyl ionone (90% min.) | FL/FR |
| ocean propanal | FL/FR |
| orris rhizome resinoid (iris pallida) | FL/FR |
| phenethyl alcohol | FL/FR |
| rhodinol | FL/FR |
fruity |
| acetyl methyl anthranilate | FL/FR |
iso | amyl benzoate | FL/FR |
para- | anisyl acetate | FL/FR |
para- | anisyl alcohol | FL/FR |
iso | butyl benzoate | FL/FR |
| cherry oxyacetate | FL/FR |
| dimethyl anthranilate | FL/FR |
| ethyl methyl-para-tolyl glycidate | FL/FR |
alpha- | methyl ionone | FL/FR |
| propiophenone | FL/FR |
| rose butanoate | FL/FR |
| tolualdehydes (mixed o,m,p) | FL/FR |
green |
iso | amyl salicylate | FL/FR |
| cinnamyl alcohol | FL/FR |
| cocoa butenal | FL/FR |
para- | dimethyl hydroquinone | FL/FR |
para- | methyl hydratropaldehyde | FL/FR |
| phenoxyethyl isobutyrate | FL/FR |
herbal |
| apium graveolens seed oil india | FL/FR |
honey |
| ethyl phenyl acetate | FL/FR |
| phenethyl phenyl acetate | FL/FR |
iso | propyl phenyl acetate | FL/FR |
meaty |
ortho- | thioguaiacol | FL |
minty |
| ethyl salicylate | FL/FR |
musk |
| ethylene brassylate | FL/FR |
dextro,laevo- | muscone | FL/FR |
musty |
2,3,5- | trimethyl pyrazine | FL/FR |
naphthyl |
para- | methyl anisole | FL/FR |
beta- | naphthyl methyl ether | FL/FR |
powdery |
ortho- | acetanisole | FL/FR |
| acetophenone | FL/FR |
beta- | naphthyl ethyl ether | FL/FR |
| powdery ketone | FL |
spicy |
| benzyl cinnamate | FL/FR |
| benzylidene acetone | FL |
| cassia bark oil china | FL/FR |
| cuminaldehyde | FL/FR |
iso | eugenyl acetate | FL/FR |
| hawthorn carbinol | FL/FR |
alpha- | methyl cinnamaldehyde | FL/FR |
| methyl isoeugenol | FL/FR |
3- | phenyl propyl alcohol | FL/FR |
sweet |
| cyclohexyl acetic acid | FL/FR |
tropical |
alpha- | amyl cinnamaldehyde | FL/FR |
vanilla |
| ethyl vanillin | FL/FR |
omega- | pentadecalactone | FL/FR |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
| vanillyl acetate | FL/FR |
waxy |
alpha- | hexyl cinnamaldehyde | FL/FR |
| hydroxycitronellal | FL/FR |
| nonanol | FL/FR |
| rhodinyl phenyl acetate | FL/FR |
woody |
| amyris wood oil | FL/FR |
iso | bornyl acetate | FL/FR |
| guaiacwood oil | FL/FR |
alpha- | irone | FL/FR |
| methyl ionyl acetate | FL/FR |
|
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
2- | anisaldehyde | o- | anisaldehyde | o- | anisic aldehyde | ortho- | anisic aldehyde | | benzaldehyde, 2-methoxy- | | benzaldehyde, o-methoxy- | o- | formyl anisole | ortho- | formyl anisole | | formylanisole, o- | 2- | methoxy benzaldehyde | 2- | methoxy-benzaldehyde | 2- | methoxybenzaldehyde | o- | methoxybenzaldehyde | ortho- | methoxybenzaldehyde | o- | methoxybenzaldehyde, natural | 2- | methoxybenzene carboxaldehyde | 2- | methoxybenzenecarboxaldehyde | 2- | methoxyphenyl formaldehyde | 2- | methoxyphenylformaldehyde | | salicylaldehyde methyl ether |
Articles:
|