Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless to pale yellow liquid to solid (est) |
Assay: | 96.00 to 100.00 %
|
Food Chemicals Codex Listed: | No |
Melting Point: | 75.00 to 85.00 °C. @ 760.00 mm Hg
|
Boiling Point: | 102.00 to 106.00 °C. @ 25.00 mm Hg
|
Acid Value: | 1.00 max. KOH/g
|
Vapor Pressure: | 0.009000 mmHg @ 25.00 °C. (est) |
Flash Point: | > 212.00 °F. TCC ( > 100.00 °C. )
|
logP (o/w): | 5.256 (est) |
Soluble in: |
| alcohol | | water, slightly | | water, 2.436 mg/L @ 25 °C (est) |
Stability: |
| APC: traces - 1% | | candle: traces - 1% | | detergent: traces - 1% | | fine fragrances: 0.5 - 5% | | shampoo: traces - 0.5% | | shower gel: traces - 0.5% | | soap: traces - 0.5% | | softener: traces - 1% |
Similar Items: note |
(-)-dodecahydrotetramethyl naphthofuran |
dodecahydrotetramethyl epoxynaphthoxepin |
dodecahydrocyclododecafuran |
Organoleptic Properties:
|
Odor Type: amber |
|
Odor Strength: | high , recommend smelling in a 10.00 % solution or less |
|
Substantivity: | > 400 hour(s) at 10.00 % in dipropylene glycol |
|
| dry woody amber ambergris musk sweet |
Odor Description: at 10.00 % in dipropylene glycol. | dry woody amber ambergris musk sweet Luebke, William tgsc, (1986) |
|
|
Flavor Type: amber |
|
| amber woody old wood tobacco powdery dry ambergris animal |
Taste Description:
| amber old wood tobacco powdery dry ambergris animal Luebke, William tgsc, (1986) |
|
Odor and/or flavor descriptions from others (if found). |
|
Firmenich |
AMBROX® DL for fragrance |
Odor Description: | An elegant amber note with a rich woody character This ingredient provides warmth, richness and elegance to all areas of perfumery from sheer florals to modern orientals. Due to its power, best effects can be achieved at lower dosages, however, higher levels are often used to provide performance and substantivity. |
|
Firmenich |
CETALOX® for fragrance |
Odor Description: | An extremely powerful and elegant amber note CETALOX® gives rich, elegant effects to all areas of perfumery from sheer florals to modern orientals. Enhanced richness, warmth and depth can be achieved at lower dosages while, at higher levels, it provides exceptional substantivity and performance. |
|
Firmenich |
CETALOX® LAEVO |
Odor Description: | An extremely powerful and elegant amber note, more ambery and sharper than CETALOX® CETALOX® LAEVO gives rich, elegant effects to all areas of perfumery, from sheer florals to modern orientals. It is highly diffusive and brings a unique ambergris effect from top note to dry down. |
|
IFF |
Ambermor DL |
Odor Description: | Strong amber with dry and woody notes |
|
IFF |
Cetalor |
Odor Description: | One of the finest ambergris notes, powerful amber, woody odor, which gives rich, elegant effects to all kinds of perfumery |
|
Perfumery Laboratory |
TSETALOKS ™ F (CETALOX ™ F) |
Odor Description: | beautiful natural aroma components whale ambergris. Sweet, with hints of fresh wood. It has a long diffusion |
|
|
Cosmetic Information:
Suppliers:
Associate Allied Chemicals |
Synambran
|
About |
Augustus Oils |
Cetalox
|
Services |
Azelis UK |
AMBROX® DL
|
Azelis UK |
CETALOX
|
BOC Sciences |
For experimental / research use only. |
AMBROX DL 95%
|
Ernesto Ventós |
AMBERMOR DL IFF
|
Ernesto Ventós |
AMBROTECH
|
Ernesto Ventós |
AMBROX DL FIRMENICH 909120
Odor: AMBERGRIS, WOODY |
Ernesto Ventós |
CETALOR IFF
|
Ernesto Ventós |
CETALOX FIRMENICH 922560
Odor: ELEGANT NOTE OF AMBAR |
Firmenich |
AMBROX® DL
for fragrance Odor: An elegant amber note with a rich woody character Use: This ingredient provides warmth, richness and elegance to all areas of perfumery from sheer florals to modern orientals. Due to its power, best effects can be achieved at lower dosages, however, higher levels are often used to provide performance and substantivity. |
Firmenich |
CETALOX® LAEVO
|
Firmenich |
CETALOX®
for fragrance Odor: An extremely powerful and elegant amber note Use: CETALOX® gives rich, elegant effects to all areas of perfumery from sheer florals to modern orientals. Enhanced richness, warmth and depth can be achieved at lower dosages while, at higher levels, it provides exceptional substantivity and performance. |
IFF |
Ambermor DL
Odor: Strong amber with dry and woody notes |
IFF |
Cetalor
Odor: One of the finest ambergris notes, powerful amber, woody odor, which gives rich, elegant effects to all kinds of perfumery |
Indukern F&F |
AMBEROX DL
Odor: AMBER, WOODY |
Indukern F&F |
AMBROTECH
Odor: WOODY, SWEET |
Liaison Carbone |
CETALOX® 922560
|
Lluch Essence |
AMBERMOR-DL PURE
|
Lluch Essence |
AMBROX DL
Odor: WOODY, AMBER LIKE |
Lluch Essence |
CETALOR
|
Penta International |
AMBROX DL
|
Penta International |
DODECAHYDRO-3a,6,6,9a-TETRAMETHYLNAPHTO-(2,1-b)-FURAN
|
Perfumery Laboratory |
Ambrox® DL 20% in Firmenich DPG (AMBROX® DL 20% DPG Firmenich)
Odor: Sweet, amber, musky aroma. It is amber naphthofuran |
Perfumery Laboratory |
TSETALOKS ™ F (CETALOX ™ F)
Odor: beautiful natural aroma components whale ambergris. Sweet, with hints of fresh wood. It has a long diffusion |
The Lermond Company |
AMBROTECH
|
The Perfumers Apprentice |
Ambrox DL
Odor: dry woody amber ambergris musk sweet |
The Perfumers Apprentice |
Cetalox (F) (crystals)
|
Vigon International |
Ambrox DL
Odor: AMBER, WOODY |
Vigon International |
Ambrox Super
|
Vigon International |
Cetalox
Odor: AMBER. |
Safety Information:
European information : |
Most important hazard(s): | Xi - Irritant |
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
|
|
Hazards identification |
|
Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
|
Pictogram | |
|
Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
|
Dermal Toxicity: |
Not determined
|
Inhalation Toxicity: |
Not determined
|
Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for amber naphthofuran usage levels up to: | | 5.0000 % in the fragrance concentrate.
|
|
Maximised Survey-derived Daily Intakes (MSDI-EU): | 1.20 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.10 (μg/capita/day) |
Structure Class: | III |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 9 |
Click here to view publication 9 |
| average usual ppm | average maximum ppm |
baked goods: | - | 0.01000 |
beverages(nonalcoholic): | - | 0.01000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | 0.01000 |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 0.01000 |
fruit ices: | - | 0.01000 |
gelatins / puddings: | - | 0.01000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 59 (FGE.59): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 (2006) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 33 (FGE.33)[1] - Six Tetrahydrofuran Derivatives from Chemical Groups 13, 14, 16 and 26 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 59, Revision 1 (FGE.59Rev1): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting and 63rd meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 Rev2 (2010) View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 3738-00-9 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 107166 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 2 |
| 3a,6,6,9a-tetramethyl-2,4,5,5a,7,8,9,9b-octahydro-1H-benzo[e][1]benzofuran |
Chemidplus: | 0003738009 |
References:
Leffingwell: | Chirality or Article |
| 3a,6,6,9a-tetramethyl-2,4,5,5a,7,8,9,9b-octahydro-1H-benzo[e][1]benzofuran |
NIST Chemistry WebBook: | Search Inchi |
Canada Domestic Sub. List: | 3738-00-9 |
Pubchem (cid): | 107166 |
Pubchem (sid): | 135063926 |
Pherobase: | View |
Other Information:
Potential Blenders and core components note
|
For Odor |
No odor group found for these |
1-(2-tert- | butyl cyclohexyl)-4-(piperidine-1-carbonyl) pyrrolidin-2-one | |
|
| amber romance fragrance | FR |
(Z)-iso | ambrettolide | FR |
aldehydic |
2,6- | dimethyl-2,18-nonadecadien-8-one | |
| dodecanal (aldehyde C-12 lauric) | FL/FR |
2- | methyl undecanal (aldehyde C-12 mna) | FL/FR |
10- | undecenal (aldehyde C-11 undecylenic) | FL/FR |
amber |
(Z)- | abienol | FL/FR |
| acetoxymethyl isolongifolene | FR |
| amber acetate | FR |
| amber butanol | FR |
| amber cyclohexanol | FR |
| amber decane | FR |
| amber furan | FR |
| amber oxepin | FR |
| amber spirolene | FR |
| ambergris naphthol | FR |
| ambergris specialty | FR |
| ambrein | FR |
| ambrette seed absolute | FL/FR |
| ambrette seed oil | FL/FR |
| ambrette seed oil CO2 extract | FL/FR |
| ambrette seed oil replacer | FR |
alpha- | ambrinol | FL/FR |
| ambrinol | FR |
| ambroxan | FL/FR |
| ambroxide | FL/FR |
| angelica root oil | FL/FR |
| cistus ladaniferus absolute resin | FL/FR |
| cistus ladaniferus resinoid | FL/FR |
| formoxymethyl isolongifolene | FR |
(cis+trans)-6,6a,7,8,9,9a- | hexahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline | FR |
| hydroxymethyl isolongifolene 50% in dpg | FR |
| labdanum absolute | FL/FR |
| labdanum oil | FL/FR |
| muscomer | FR |
(cis+trans)-1,1,2,3,3- | pentamethyl-2,3,3a,4,5,9b-hexahydro-1H-7,9-diazacyclopenta[a]naphthalene | |
animal |
| animal carbolactone | FR |
| costus valerolactone | FR |
| indole | FL/FR |
2- | methyl-4-(camphenyl-8) cyclohexanone | FR |
| musk indenofuran | FR |
balsamic |
| amyris wood oil | FL/FR |
siam | benzoin resinoid | FL/FR |
laevo- | borneol | FL/FR |
| brachyleana hutchinsii wood oil | FR |
| juniper berry concrete | FR |
| opoponax absolute (commiphora erythraea var. glabrescens engle) | FL/FR |
| opoponax resinoid (commiphora erythraea var. glabrescens engle) | FR |
| opoponax resinoid replacer | FR |
| oriental specialty | FR |
| valerian rhizome absolute | FL/FR |
berry |
| raspberry ketone | FL/FR |
| ethyl maltol | FL/FR |
| immortelle absolute | FL/FR |
| maltol | FL/FR |
citrus |
bitter | orange peel oil | FL/FR |
bitter | orange peel oil brazil | FL/FR |
bitter | orange peel oil italy | FL/FR |
coconut |
(S)-gamma- | hexalactone | |
gamma- | nonalactone (aldehyde C-18 (so-called)) | FL/FR |
gamma- | octalactone | FL/FR |
earthy |
(Z)- | linalool oxide (furanoid) | FL/FR |
fatty |
| decanol | FL/FR |
floral |
| acetophenone | FL/FR |
| amyl benzoate | FL/FR |
iso | amyl salicylate | FL/FR |
| angel wings fragrance | FR |
| bois de rose oil brazil | FL/FR |
| boronia butenal | FR |
iso | butyl salicylate | FL/FR |
| cyclamen aldehyde | FL/FR |
| dihydrojasmone | FL/FR |
| floral pyranol | FR |
| heliotropyl acetone | FL/FR |
alpha- | hexyl cinnamaldehyde | FL/FR |
beta- | ionone | FL/FR |
| lilyall | FR |
laevo- | linalool | FL/FR |
| methyl dihydrojasmonate | FL/FR |
N- | methyl ionone | FR |
alpha-iso | methyl ionone (50% min.) | FL/FR |
| methyl ionyl acetate | FL/FR |
2- | methyl naphthalene | FL/FR |
| nerolidol | FL/FR |
| nonanol | FL/FR |
| ocean propanal | FL/FR |
bitter | orangeflower concrete morocco | FR |
| phenethyl phenyl acetate | FL/FR |
fruity |
gamma- | decalactone | FL/FR |
(R)-gamma- | dodecalactone | FL/FR |
2- | ethyl butyl 2-butenoate | |
| menthyl isovalerate | FL/FR |
gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
| valeriana officinalis root extract | FL/FR |
green |
| diphenyl oxide | FL/FR |
| galbanum oil | FL/FR |
iso | green methanoindene | FR |
| methyl cyclocitrone (IFF) | FR |
| methyl heptine carbonate | FL/FR |
(E,Z)-2,6- | nonadien-1-ol | FL/FR |
| rose leaf absolute (rosa centifolia) | FL/FR |
| violet leaf absolute | FL/FR |
hay |
| beeswax absolute | FL/FR |
herbal |
(+)-alpha- | campholenic aldehyde | FL/FR |
| daucus carota fruit oil | FL/FR |
delta- | elemene | FL/FR |
| herbal carene | FR |
| tea leaf absolute | FL/FR |
melon |
| melon heptenal | FL/FR |
(Z)-6- | nonenal | FL/FR |
| watermelon ketone | FR |
mentholic |
iso | pulegyl acetate | FL/FR |
mossy |
| veramoss (IFF) | FR |
musk |
| acetyl ethyl tetramethyl tetralin replacer | FR |
| dehydro beta-linalool | FL/FR |
| musk amberol | FR |
| musk decanolide | FR |
| musk dimethyl indane | FL/FR |
| musk indane | FR |
| musk indanone | FR |
| musk lactone | FR |
| musk methyl ketone | FR |
6,7,8,9- | tetrahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline | FR |
6,6,10,10- | tetramethyl-5,7,8,9,10,10a-hexahydro-6H-6a,9-methanobenzo[H]quinazoline | |
musty |
ketoiso | phorone | FL/FR |
spicy |
| cassia bark oil china | FL/FR |
black | currant bud absolute | FL/FR |
2,5- | dimethyl bicyclo(3.2.1)-2-octen-3-yl acetate + 1,4-dimethyl bicyclo(3.2.1)-2-octen-3-yl acetate | FR |
iso | eugenyl acetate | FL/FR |
| ginger root absolute | FL/FR |
| grains of paradise oil | FL/FR |
| methyl heptadienone | FL/FR |
terpenic |
| angelica seed oil | FL/FR |
| frankincense oil | FL/FR |
tonka |
| tonka bean absolute | FR |
waxy |
1- | dodecanol | FL/FR |
| ethyl laurate | FL/FR |
woody |
| acetyl cedrene | FR |
| agarwood oil (aetoxylon sympetalum) | FR |
| amber carbinol | FR |
| amber decatriene | FR |
| amber dioxane | FR |
| amber dodecane | FR |
| amber formate | FR |
| ambrene acetal | FR |
| cabreuva wood oil | FR |
beta- | caryophyllene oxide | FL/FR |
atlas | cedarwood absolute | FR |
atlas | cedarwood oil | FR |
| cedrela wood oil | FR |
alpha- | cedrene epoxide | FR |
| cedrenyl acetate | FR |
| cedryl acetate | FL/FR |
| cedryl methyl ether | FR |
| cistus ladaniferus gum | FR |
| cistus twig/leaf absolute | FR |
| cistus twig/leaf oil | FL/FR |
| guaiacwood oil | FL/FR |
| guaiacwood oil 20% in gurjun balsam oil | FR |
| gurjun balsam oil | FR |
| hinoki root oil | FR |
| homalomena rubescens root oil | FR |
| hydroxyambran | FR |
| labdanum concrete | FR |
| labdanum ethanone | FR |
iso | longifolene epoxide | FR |
iso | longifolene ketone | FR |
para- | menth-3-en-1-ol | FL/FR |
2- | methoxy-4-vinyl phenol | FL/FR |
| methyl 2,6,10-trimethyl cyclododeca-2,5,9-trienyl ketone | FR |
| methyl cedryl ketone | FL/FR |
delta- | methyl ionone | FL/FR |
| methyl vetivate | FR |
| patchouli ethanone | FR |
| patchouli oil | FL/FR |
| sandal pentenol | FL/FR |
| sandalwood oil CO2 extract | FL/FR |
| sandalwood oil west australia (santalum spicatum) | FR |
| santall | FR |
| sclarene | |
| sclareolide | FL/FR |
| spikenard oil CO2 extract | FL/FR |
| spruce needle oil canada | FL/FR |
| timber propanol | FR |
| tobacarol (IFF) | FR |
| tobacco nonene | FR |
| woody acetate | FR |
| woody cyclohexanone | FR |
| woody dioxolane | FR |
| woody dodecane | FR |
| woody ether | FR |
| woody nonane (ethoxy) | FR |
|
For Flavor |
|
No flavor group found for these |
| ambroxide | FL/FR |
| amyl benzoate | FL/FR |
| cistus ladaniferus resinoid | FL/FR |
| dehydro beta-linalool | FL/FR |
2,6- | dimethyl-2,18-nonadecadien-8-one | |
(R)-gamma- | dodecalactone | FL/FR |
delta- | elemene | FL/FR |
2- | ethyl butyl 2-butenoate | |
| grains of paradise oil | FL/FR |
(S)-gamma- | hexalactone | |
(Z)- | linalool oxide (furanoid) | FL/FR |
para- | menth-3-en-1-ol | FL/FR |
delta- | methyl ionone | FL/FR |
(cis+trans)-1,1,2,3,3- | pentamethyl-2,3,3a,4,5,9b-hexahydro-1H-7,9-diazacyclopenta[a]naphthalene | |
| sandal pentenol | FL/FR |
| sclarene | |
| spikenard oil CO2 extract | FL/FR |
6,6,10,10- | tetramethyl-5,7,8,9,10,10a-hexahydro-6H-6a,9-methanobenzo[H]quinazoline | |
amber |
| ambrette seed oil | FL/FR |
| ambrette seed oil CO2 extract | FL/FR |
alpha- | ambrinol | FL/FR |
| angelica seed oil | FL/FR |
| cistus ladaniferus absolute resin | FL/FR |
| labdanum absolute | FL/FR |
| labdanum oil | FL/FR |
animal |
| indole | FL/FR |
apple |
(E,Z)-2,6- | nonadien-1-ol | FL/FR |
balsamic |
siam | benzoin resinoid | FL/FR |
| opoponax absolute (commiphora erythraea var. glabrescens engle) | FL/FR |
berry |
| heliotropyl acetone | FL/FR |
| raspberry ketone | FL/FR |
bitter |
1-(2-tert- | butyl cyclohexyl)-4-(piperidine-1-carbonyl) pyrrolidin-2-one | |
brown |
| beeswax absolute | FL/FR |
camphoreous |
laevo- | borneol | FL/FR |
caramellic |
| caramel furanone | FL |
| ethyl maltol | FL/FR |
| maltol | FL/FR |
citrus |
laevo- | linalool | FL/FR |
bitter | orange peel oil | FL/FR |
bitter | orange peel oil italy | FL/FR |
ketoiso | phorone | FL/FR |
coconut |
gamma- | nonalactone (aldehyde C-18 (so-called)) | FL/FR |
cooling |
iso | butyl salicylate | FL/FR |
creamy |
gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
fatty |
10- | undecenal (aldehyde C-11 undecylenic) | FL/FR |
floral |
| bois de rose oil brazil | FL/FR |
| dihydrojasmone | FL/FR |
| methyl dihydrojasmonate | FL/FR |
alpha-iso | methyl ionone (50% min.) | FL/FR |
| ocean propanal | FL/FR |
fruity |
gamma- | decalactone | FL/FR |
| menthyl isovalerate | FL/FR |
bitter | orange peel oil brazil | FL/FR |
| valerian rhizome absolute | FL/FR |
| valeriana officinalis root extract | FL/FR |
green |
iso | amyl salicylate | FL/FR |
| angelica root oil | FL/FR |
(+)-alpha- | campholenic aldehyde | FL/FR |
| cyclamen aldehyde | FL/FR |
| diphenyl oxide | FL/FR |
| galbanum oil | FL/FR |
| immortelle absolute | FL/FR |
| melon heptenal | FL/FR |
| methyl heptadienone | FL/FR |
| methyl heptine carbonate | FL/FR |
| nerolidol | FL/FR |
(Z)-6- | nonenal | FL/FR |
iso | phorone | FL |
| rose leaf absolute (rosa centifolia) | FL/FR |
| violet leaf absolute | FL/FR |
herbal |
| daucus carota fruit oil | FL/FR |
honey |
| phenethyl phenyl acetate | FL/FR |
lactonic |
gamma- | octalactone | FL/FR |
musk |
| musk dimethyl indane | FL/FR |
oily |
2- | methyl naphthalene | FL/FR |
powdery |
| acetophenone | FL/FR |
smoky |
2- | methoxy-4-vinyl phenol | FL/FR |
dextro- | xylose | FL |
soapy |
| dodecanal (aldehyde C-12 lauric) | FL/FR |
1- | dodecanol | FL/FR |
spicy |
| cassia bark oil china | FL/FR |
black | currant bud absolute | FL/FR |
iso | eugenyl acetate | FL/FR |
| ginger root absolute | FL/FR |
tea |
| tea leaf absolute | FL/FR |
waxy |
| decanol | FL/FR |
| ethyl laurate | FL/FR |
alpha- | hexyl cinnamaldehyde | FL/FR |
2- | methyl undecanal (aldehyde C-12 mna) | FL/FR |
| nonanol | FL/FR |
woody |
(Z)- | abienol | FL/FR |
| ambrette seed absolute | FL/FR |
| ambroxan | FL/FR |
| amyris wood oil | FL/FR |
beta- | caryophyllene oxide | FL/FR |
| cedryl acetate | FL/FR |
| cistus twig/leaf oil | FL/FR |
| frankincense oil | FL/FR |
| guaiacwood oil | FL/FR |
beta- | ionone | FL/FR |
| methyl cedryl ketone | FL/FR |
| methyl ionyl acetate | FL/FR |
| patchouli oil | FL/FR |
iso | pulegyl acetate | FL/FR |
| sandalwood oil CO2 extract | FL/FR |
| sclareolide | FL/FR |
| spruce needle oil canada | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| amber naphthofuran | | ambermor DL (IFF) | | amborl DL | | ambrox DL (Firmenich) | | cetalor (IFF) | | cetalox (Firmenich) | | cetalox laevo (Firmenich) | | dodecahydro-3a,6,6,9a-tetramethyl naphtho(2,1-beta)furan | | dodecahydro-3a,6,6,9a-tetramethylnaphtho(2,1-b)furan | | dodecahydro-3a,6,6,9a-tetramethylnaphto-(2,1-b)-furan | | dodecahydro-3a-,6,6,9a-tetramethyl(2,1beta)furan | | dodecahydrotetramethyl naphthofuran | | fixambrene | | naphtho(2,1-b)furan, dodecahydro-3a,6,6,9a-tetramethyl- | | naphtho[2,1-b]furan, dodecahydro-3a,6,6,9a-tetramethyl- | | synambran | | tetramethyl dodecahydro-3a,6,6,9a-naphtho(2,1-b)furan | | tetramethyl perhydronaphthofurane | 1,5,5,9- | tetramethyl-13-oxatricyclo(8.3.0.0.(4.9))tridecane | 3a,6,6,9a- | tetramethyl-2,4,5,5a,7,8,9,9b-octahydro-1H-benzo[e][1]benzofuran | 1,6,10,10- | tetramethyl-5-oxatricyclo[7.4.0.0<2,6>]tridecane | 3a,6,6,9a- | tetramethyl-dodecahydro-naphtho[2,1-b]furan | 3a,6,6,9a- | tetramethyldodecahydronaphtho[2,1-b]furan | 3a,6,6,9a- | tetramethylperhydronaphtho[2,1-b]furan |
Articles:
Info: | Ambrox / Ambroxan |
Google Patents: | (+)-Ambrox, process for production thereof and use thereof |
US Patents: | 8,222,200 - Organic compounds |
PubMed: | Toward a biosynthetic route to sclareol and amber odorants. |
PubMed: | A diterpene synthase from the clary sage Salvia sclarea catalyzes the cyclization of geranylgeranyl diphosphate to (8R)-hydroxy-copalyl diphosphate. |
PubMed: | Biotransformation of perfumery terpenoids, (-)-ambrox® by a fungal culture Macrophomina phaseolina and a plant cell suspension culture of Peganum harmala. |
PubMed: | Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture. |
PubMed: | Communic acids: occurrence, properties and use as chirons for the synthesis of bioactive compounds. |
PubMed: | Isolation, chemical, and biotransformation routes of labdane-type diterpenes. |
PubMed: | Antibacterial and cytotoxic activity of the acetone extract of the flowers of Salvia sclarea and some natural products. |
PubMed: | Chiral decalins: preparation from oleanolic acid and application in the synthesis of (-)-9-epi-ambrox. |
PubMed: | Biotransformation of (-)-ambrox by cell suspension cultures of Actinidia deliciosa. |
PubMed: | Chiral proton donor reagents: tin tetrachloride--coordinated optically active binaphthol derivatives. |
PubMed: | Enantio- and diastereoselective stepwise cyclization of polyprenoids induced by chiral and achiral LBAs. A new entry to (-)-ambrox, (+)-podocarpa-8,11,13-triene diterpenoids, and (-)-tetracyclic polyprenoid of sedimentary origin. |
PubMed: | Oxidative metabolism of ambrox and sclareolide by Botrytis cinerea. |
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