Category: solvents/deluents for cosmetic, flavor and/or fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | white crystals (est) |
Assay: | 99.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Melting Point: | 110.00 to 115.00 °C. @ 760.00 mm Hg
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Boiling Point: | 433.00 to 434.00 °C. @ 760.00 mm Hg
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Flash Point: | 370.00 °F. TCC ( 187.78 °C. )
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logP (o/w): | 0.630 |
Soluble in: |
| alcohol | | ether | | water, 1018 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
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Odor Type: odorless |
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Odor Strength: | none |
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Odor Description: at 100.00 %. | odorless |
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Flavor Type: bitter |
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| bitter citrus |
Taste Description: at 100.00 ppm. | Bitters-like, with a citrus tonic flavor Mosciano, Gerard P&F 16, No. 1, 31, (1991) |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | None - None found. |
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | solvents/deluents for cosmetic, flavor and/or fragrance agents |
Recommendation for alpha-dextro-pentaacetyl glucose usage levels up to: | | not for fragrance use.
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Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | - | 1500.00000 |
beverages(nonalcoholic): | - | 100.00000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | - |
fruit ices: | - | - |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
References:
| [2,3,5-triacetyloxy-6-(acetyloxymethyl)oxan-4-yl] acetate |
NIST Chemistry WebBook: | Search Inchi |
Pubchem (cid): | 79064 |
Pubchem (sid): | 135036643 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
(2S,3R,4S,5R,6R)-6-( | acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate | alpha-D- | glucopyranose pentaacetate | alpha-dextro- | glucopyranose pentaacetate | alpha-D- | glucose pentaacetate | alpha-dextro- | glucose pentaacetate | | hexopyranose, pentaacetate | 1,2,3,4,6- | penta-O-acetyl-a-D-galactopyranose | 1,2,3,4,6- | penta-O-acetyl-a-D-glucopyranose | 1,2,3,4,6- | penta-O-acetyl-a-D-mannopyranose | 1,2,3,4,6- | penta-O-acetylhexopyranose | alpha-D- | pentaacetyl glucose | alpha-dextro- | pentaacetyl glucose | 1,2,3,4,6- | pentaacetyl-alpha-dextro-glucose | alpha- | pentaacetyl-D-glucose | alpha- | pentaacetyl-dextro-glucose | [3,4,5,6- | tetrakis(acetyloxy)tetrahydro-2H-pyran-2-yl]methyl acetate | 3,4,5- | triacetyloxy-6-(acetyloxymethyl)-2H-3,4,5,6-tetrahydropyran-2-yl acetate | [2,3,5- | triacetyloxy-6-(acetyloxymethyl)oxan-4-yl] acetate |
Articles:
PubMed: | Insulin release: the receptor hypothesis. |
PubMed: | Deuterium-induced isotope effects on the 13C chemical shifts of α-D-glucose pentaacetate. |
PubMed: | Selective formation of glycosidic linkages of N-unsubstituted 4-hydroxyquinolin-2-(1H)-ones. |
PubMed: | Sugar acetates as CO2-philes: molecular interactions and structure aspects from absorption measurement using quartz crystal microbalance. |
PubMed: | A simple preparation of 2,3,4,6-tetra-o-acyl-gluco-, galacto- and mannopyranoses and relevant theoretical study. |
PubMed: | Preparation of nucleoside-carbohydrate phosphodiester prodrug analogues by chemoenzymatic procedure. |
PubMed: | Directed assembly of sub-nanometer thin organic materials with programmed-size nanopores. |
PubMed: | Measurement of gluconeogenesis using glucose fragments and mass spectrometry after ingestion of deuterium oxide. |
PubMed: | Characterization of a new rhamnogalacturonan acetyl esterase from Bacillus halodurans C-125 with a new putative carbohydrate binding domain. |
PubMed: | YesT: a new rhamnogalacturonan acetyl esterase from Bacillus subtilis. |
PubMed: | Examination of glass transitions in CO(2)-processed, peracetylated sugars using sum frequency generation spectroscopy. |
PubMed: | Mirror-image carbohydrates: synthesis of the unnatural enantiomer of a blood group trisaccharide. |
PubMed: | Monosaccharide esters: new tools in biomedicine. |
PubMed: | Monosaccharide esters: clinically relevant? |
PubMed: | Synthesis of 2-thiohydantoins and their S-glucosylated derivatives as potential antiviral and antitumor agents. |
PubMed: | Synthesis and antiperoxidant activity of new phenolic O-glycosides. |
PubMed: | Metabolism of alpha-D-[1,2-13C]glucose pentaacetate and alpha-D-glucose penta[2-13C]acetate in rat hepatocytes. |
PubMed: | Activation of glycogen synthase a in hepatocytes exposed to alpha-D-glucose pentaacetate. |
PubMed: | Stimulation of insulin synthesis and release by alpha-D-glucose pentaacetate in pancreatic islets from human subjects. |
PubMed: | Metabolism of D-[1,2-13C]glucose and alpha-D-[1,2-13C]glucose pentaacetate in tumoral pancreatic islet cells. |
PubMed: | Metabolism of d-glucose and its pentaacetate ester in muscles and pancreatic islets of GLUT4 null mice. |
PubMed: | Effect of D-mannoheptulose upon the cationic and secretory responses to alpha-D-glucose pentaacetate in perifused rat pancreatic islets. |
PubMed: | Differences in the time course of the metabolic response of B and non-B pancreatic islet cells to D-glucose and metabolized or non-metabolized hexose esters. |
PubMed: | Effects of extracellular pH upon the insulinotropic action of alpha-D-glucose pentaacetate. |
PubMed: | Isomeric and anomeric specificity of the metabolic and secretory response of rat pancreatic islets to glucose pentaacetate. |
PubMed: | Regioselective hydrolysis of peracetylated alpha-D-glycopyranose catalyzed by immobilized lipases in aqueous medium. A facile preparation of useful intermediates for oligosaccharide synthesis. |
PubMed: | Insulinotropic action of monosaccharide esters: therapeutic perspectives. |
PubMed: | Opposite effects of D-glucose pentaacetate and D-galactose pentaacetate anomers on insulin release evoked by succinic acid dimethyl ester in rat pancreatic islets. |
PubMed: | Effects of alpha-D- and beta-L-glucose pentaacetate on effluent radioactivity from pancreatic islets labelled with [(32)P]phosphate and myo-[2-(3)H]inositol. |
PubMed: | Effects of artificial sweeteners on insulin release and cationic fluxes in rat pancreatic islets. |
PubMed: | Effects of hexose pentaacetates on electrical activity and cytosolic Ca2+ in mouse pancreatic islets. |
PubMed: | Failure of streptozotocin tetraacetate to undergo extensive hydrolysis and to inhibit D-glucose metabolism and insulinotropic action in rat pancreatic islets. |
PubMed: | The riddle of L-glucose pentaacetate insulinotropic action (review). |
PubMed: | Insulinotropic action of the polyacetate esters of two non-nutrient monosaccharides in normal and diabetic rats. |
PubMed: | Insulinotropic action of beta-L-glucose pentaacetate. |
PubMed: | Monosaccharide esters: new tools in biomedical research. |
PubMed: | Hydrolysis of hexose pentaacetate esters in rat pancreatic islets. |
PubMed: | Dual mode of action of glucose pentaacetates on hormonal secretion from the isolated perfused rat pancreas. |
PubMed: | Comparison of the effects of D-mannoheptulose and its hexaacetate ester on D-glucose metabolism and insulinotropic action in rat pancreatic islets. |
PubMed: | Insulinotropic action of alpha-D-glucose pentaacetate: metabolic aspects. |
PubMed: | Stimulation by hexose esters of lactate production by rat erythrocytes: insensitivity to 3-O-methyl-D-glucose and inhibition by 2-deoxy-D-glucose and its tetraacetic ester. |
PubMed: | Resistance of the insulinotropic action of alpha-D-glucose and beta-L-glucose pentaacetates to cholera and pertussis toxins. |
PubMed: | Synergistic insulinotropic action of succinate, acetate, and glucose esters in islets from normal and diabetic rats. |
PubMed: | Insulinotropic action of the polyacetate esters of metabolized and non-metabolized monosaccharides in pancreatic islets from normal and diabetic rats. |
PubMed: | Bitter taste of monosaccharide pentaacetate esters. |
PubMed: | Insulinotropic action of alpha-D-glucose pentaacetate: functional aspects. |
PubMed: | Stimulation of insulin release by alpha-D-glucose pentaacetate. |
PubMed: | SW.B6-Soa(b) nontaster congenic strains completed and a sucrose octaacetate congenic quartet tested with other bitters. |
PubMed: | Mass isotopomer pattern and precursor-product relationship. |
PubMed: | Esterase Activities of Fibrobacter succinogenes subsp. succinogenes S85. |
PubMed: | Preparation of various glucose esters via lipase-catalyzed hydrolysis of glucose pentaacetate. |
PubMed: | Rapid and specific isolation of radioactive glucose from biological samples. |
PubMed: | Utilization of propionic acid by the L4 and adult stages of Cooperia punctata (Nematoda: Trichostrongylidae) grown in vitro. |
PubMed: | Rapid determination of (carbon-14) glucose specific radioactivity for in vivo glucose kinetics. |
PubMed: | DETERMINATION OF THE SPECIFIC ACTIVITY OF LABELED BLOOD GLUCOSE BY LIQUID SCINTILLATION USING GLUCOSE PENTAACETATE. |
PubMed: | The suitability of beta-D-glucose pentaacetate for food use. I. The subscute toxicity of beta-D-glucose pentaacete. |
PubMed: | The suitability of beta-D-glucose pentaacetate for food use. II. Studies on the absorption and metabolism. |
PubMed: | Action of the Grignard reagent on beta-d-glucose pentaacetate. |
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