Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless solid (est) |
Assay: | 98.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Melting Point: | 34.00 to 38.00 °C. @ 760.00 mm Hg
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Boiling Point: | 137.00 °C. @ 2.00 mm Hg
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Congealing Point: | 36.00 °C.
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Flash Point: | > 220.00 °F. TCC ( > 104.44 °C. )
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logP (o/w): | 6.100 |
Shelf Life: | 36.00 month(s) or longer if stored properly. |
Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
Soluble in: |
| alcohol | | dipropylene glycol | | water, 0.1484 mg/L @ 25 °C (est) |
Stability: |
| alcoholic solution: 0.5 - 5% | | antiperspirant | | candle: 0.5 - 5% | | deodorant spray | | detergent: 0.5 - 5% | | hair spray | | lotion | | non-discoloring in most media | | soap: 0.5 - 5% | | shampoo: 0.5 - 5% | | shower gel: 0.5 - 5% | | softener: 0.5 - 5% | | APC: 0.5 - 5% |
Organoleptic Properties:
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Odor Type: musk |
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Odor Strength: | high , recommend smelling in a 10.00 % solution or less |
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Substantivity: | 400 hour(s) at 10.00 % in dipropylene glycol |
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| musk animal powdery natural fruity |
Odor Description: at 10.00 % in dipropylene glycol. | musk animal powdery natural fruity Luebke, William tgsc, (1983) |
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| tobacco coumarinic heliotrope powdery licorice brown |
Odor Description:
| Tobacco, coumarin, heliotropine, powdery, licorice and brown Mosciano, Gerard P&F 22, No. 5, 67, (1997) |
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Flavor Type: vanilla |
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| vanilla powdery heliotrope creamy licorice |
Taste Description: at 75.00 ppm. | Vanilla bean, powdery heliotropine, creamy and licorice Mosciano, Gerard P&F 22, No. 5, 67, (1997) |
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Odor and/or flavor descriptions from others (if found). |
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Firmenich |
EXALTOLIDE® TOTAL for fragrance |
Odor Description: | This quality of EXALTOLIDE® is an extremely fine and elegant musk but more cost effective. EXALTOLIDE® TOTAL is one of the finest synthetic musk notes that possesses a very natural EXALTOLIDE® TOTAL adds depth and roundness to a wide variety of
creations but it also has a synergistic effect on the bouquet of a fragrance. It has an especially sensual effect on skin. |
Taste Description: | sweet powdery soapy |
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Firmenich |
EXALTOLIDE® for fragrance |
Odor Description: | An extremely fine and elegant musk. EXALTOLIDE® is one of the finest synthetic musk notes that possesses a very natural quality EXALTOLIDE® adds depth and roundness to a wide variety of creations but it also has a synergistic effect on the bouquet of a fragrance. It has an especially sensual effect on skin. |
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Symrise |
Macrolide® supra |
Odor Description: | warm, elegant, cosmetic and caring balsamic musk type with floral elements Stable in: body lotion (good), shampoo (good), soap (very good), ap roll-on (very good), powder (good), cleaner citric (poor), cleaner apc (very good), bleach (poor). |
Taste Description: | Musk, Perfumistic, Soapy Useful in: brown nuts, vanilla, fruity red, fruity tropical, fruity others, sweet others, alcoholics. |
|
Symrise |
Macrolide® |
Odor Description: | fine, elegant macrocyclic musk lactone note with a high impact and animalic, balsamic notes Stable in: body lotion (good), shampoo (very good), soap (very good), ap roll-on (very good), powder (good), cleaner citric (good), cleaner apc (very good), bleach (poor). |
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Moellhausen |
MACROLIDE SUPRA |
Odor Description: | powerful musk, herbal note (angelica root- like) |
Taste Description: | sweet, soap, musk-pear like |
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Bedoukian Research |
PENTALIDE (CYCLOPENTADECANOLIDE) 98.5% (sum of isomers) |
Odor Description: | An elegant, pleasant sweet animal musky note Especially useful in alcoholic, cosmetic, and soap fragrances. |
Taste Description: | musk Vanilla bean, powdery heliotropine, creamy & licorice. |
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PerfumersWorld |
Exaltolide Pentadecanolide |
Odor Description: | sweet powdery musk woody powerful musk |
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Pell Wall Perfumes |
Exaltolide |
Odor Description: | sweet, musky-animal, rich, herbal Arctander describes it like this: “Delicately animal, musky and sweet, extremely tenacious odor of outstanding uniformity. Its fixative effect is absolutely unusual in that it is not a physical fixation, but a true fixative and mellowing effect at incredibly low concentrateion of usage. The effect of perfumes containing this Lactone differ from others in the excellent ‘wearability’ introduced by the Lactone. This is particularly conspicuous when the perfume is applied to the skin.”
According to Philip Kraft, Exaltolide “is probably the commercial musk with the least side notes.” He therefore recommends using it as a benchmark for grasping the typical odor profile of musk odorants. |
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Cosmetic Information:
Suppliers:
Associate Allied Chemicals |
Macrolide Supra
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About |
Augustus Oils |
Omega-Pentadecalactone
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Services |
Aurochemicals |
omega-PENTADECALACTONE, Natural
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Azelis UK |
EXALTOLIDE TOTAL
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Azelis UK |
EXALTOLIDE
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Berjé |
Cyclo Penta Decanolide
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Media |
BOC Sciences |
For experimental / research use only. |
Oxacyclohexadecan-2-one 95%
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Charkit Chemical |
OMEGA-PENTADECALACTONE
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Creatingperfume.com |
EXALTOLIDE® TOTAL
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Creatingperfume.com |
Macrolide® supra (Symrise)
Odor: Musky, balsamic, red fruit |
Ernesto Ventós |
CYCLOPENTADECANOLIDE (MACROLIDE)
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Ernesto Ventós |
EXALTOLIDE FIRMENICH 941962
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Ernesto Ventós |
EXALTOLIDE TOTAL FIRMENICH 935985
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Ernesto Ventós |
OMEGA-PENTADECALACTONA, US NATURAL
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Firmenich |
EXALTOLIDE® TOTAL
for fragrance Odor: This quality of EXALTOLIDE® is an extremely fine and elegant musk but more cost effective. EXALTOLIDE® TOTAL is one of the finest synthetic musk notes that possesses a very natural Use: EXALTOLIDE® TOTAL adds depth and roundness to a wide variety of
creations but it also has a synergistic effect on the bouquet of a fragrance. It has an especially sensual effect on skin. |
Firmenich |
EXALTOLIDE®
for fragrance Odor: An extremely fine and elegant musk. EXALTOLIDE® is one of the finest synthetic musk notes that possesses a very natural quality Use: EXALTOLIDE® adds depth and roundness to a wide variety of creations but it also has a synergistic effect on the bouquet of a fragrance. It has an especially sensual effect on skin. |
Indukern F&F |
PENTALIDE
Odor: MUSK, HERBAL |
Indukern F&F |
THIBETOLIDE
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Liaison Carbone |
EXALTOLIDE® 941962
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Lluch Essence |
CYCLO PENTA DECANOLIDE 92%
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Lluch Essence |
CYCLO PENTA DECANOLIDE 98,5%
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M&U International |
omega-Pentadecalactone
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Moellhausen |
MACROLIDE SUPRA
Odor: powerful musk, herbal note (angelica root- like) Flavor: sweet, soap, musk-pear like |
PCW France |
Pentadecanolide
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Steps to a fragranced product |
Pell Wall Perfumes |
Exaltolide
Odor: sweet, musky-animal, rich, herbal Use: Arctander describes it like this: “Delicately animal, musky and sweet, extremely tenacious odor of outstanding uniformity. Its fixative effect is absolutely unusual in that it is not a physical fixation, but a true fixative and mellowing effect at incredibly low concentrateion of usage. The effect of perfumes containing this Lactone differ from others in the excellent ‘wearability’ introduced by the Lactone. This is particularly conspicuous when the perfume is applied to the skin.”
According to Philip Kraft, Exaltolide “is probably the commercial musk with the least side notes.” He therefore recommends using it as a benchmark for grasping the typical odor profile of musk odorants. |
Penta International |
CYCLOPENTADECANOLIDE FCC
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Penta International |
CYCLOPENTADECANOLIDE
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Perfumer Supply House |
Exaltolide 100%
Odor: A sweet musky animalic note |
PerfumersWorld |
Exaltolide Pentadecanolide 50% in DPG
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PerfumersWorld |
Exaltolide Pentadecanolide
Odor: sweet powdery musk woody powerful musk |
Perfumery Laboratory |
EXALTOLID ™ 100 Firmenich (EXALTOLIDE ™ 100 Firmenich)
Odor: Elegant sweet musk with a delicate animalistic touch |
Phoenix Aromas & Essential Oils |
Cyclopentadecanolide
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R C Treatt & Co Ltd |
Cyclo Penta Decanolide
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Reincke & Fichtner |
omega-Pentadecalactone
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Sigma-Aldrich |
omega-Pentadecalactone, ≥98%, FG
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Certified Food Grade Products |
Soda Aromatic |
Pentalide
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SRS Aromatics |
CYCLOPENTADECANOLIDE
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SRS Aromatics |
MACROLIDE SUPRA (FG)
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Symrise |
Cyclopentadecanolide PH
min. 99.5% Odor: musky, balsamic, red fruit Use: Stable in: body lotion (good), shampoo (very good), soap (very good), ap roll-on (very good), detergent powder conc. (good), cleaner citric (good), cleaner apc (very good), bleach (poor) |
Symrise |
Macrolide® supra
Odor: warm, elegant, cosmetic and caring balsamic musk type with floral elements Use: Stable in: body lotion (good), shampoo (good), soap (very good), ap roll-on (very good), powder (good), cleaner citric (poor), cleaner apc (very good), bleach (poor). Flavor: Musk, Perfumistic, Soapy Useful in: brown nuts, vanilla, fruity red, fruity tropical, fruity others, sweet others, alcoholics. |
Symrise |
Macrolide®
Odor: fine, elegant macrocyclic musk lactone note with a high impact and animalic, balsamic notes Use: Stable in: body lotion (good), shampoo (very good), soap (very good), ap roll-on (very good), powder (good), cleaner citric (good), cleaner apc (very good), bleach (poor). |
Synerzine |
omega-Pentadecalactone
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TCI AMERICA |
For experimental / research use only. |
15-Pentadecanolactone >98.0%(GC)
|
The John D. Walsh Company |
Exaltolide
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The Lermond Company |
CYCLO PENTA DECANOLIDE
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The Perfumers Apprentice |
Exaltolide 100 (50% IPM)
Odor: Fine, elegant, sweet musk note. delicately animal |
The Perfumers Apprentice |
Exaltolide 100 (Crystalline Solid)
Odor: Fine, elegant, sweet musk note. delicately animal |
United International |
Cyclopentadecanolide
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Vigon International |
Exaltolide Total
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Vigon International |
Exaltolide
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Vigon International |
Macrolide Supra (omega Pentadecalactone)
Odor: This quality of EXALTOLIDE® is an extremely fine and elegant musk but more cost effective. EXALTOLIDE® TOTAL is one of the finest synthetic musk notes that possesses a very natural |
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | N - Dangerous for the environment. |
R 53 - May cause long-term adverse effects in the aquatic wnvironment. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
Acute toxicity, Oral (Category 4), H302
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GHS Label elements, including precautionary statements |
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Pictogram | |
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Signal word | Warning |
Hazard statement(s) |
H302 - Harmful if swallowed
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Precautionary statement(s) |
P264 - Wash skin thouroughly after handling. P270 - Do not eat, drink or smoke when using this product. P301 + P312 - IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P330 - Rinse mouth. P501 - Dispose of contents/ container to an approved waste disposal plant.
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Human Experience: |
10 % solution: no irritation or sensitization. |
Oral/Parenteral Toxicity: |
oral-rat LD50 > 5000 mg/kg (Levenstein, 1974c)
oral-rat LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 13, Pg. 787, 1975.
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Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 13, Pg. 787, 1975.
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
IFRA Critical Effect: | Dermal sensitization and systemic toxicity |
IFRA: | View Standard |
View IFRA Standards Library for complete information. |
Please review Amendment 49 IFRA documentation for complete information. |
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%): |
Category 1: Products applied to the lips |
0.42 % |
Category 2: Products applied to the axillae |
0.13 % |
Category 3: Products applied to the face/body using fingertips |
2.50 % |
Category 4: Products related to fine fragrance |
2.40 % |
| Category 5: Products applied to the face and body using the hands (palms), primarily leave-on |
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on |
0.60 % |
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on |
0.60 % |
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on |
0.60 % |
Category 5D: Baby Creams, baby Oils and baby talc |
0.20 % |
Category 6: Products with oral and lip exposure |
1.40 % |
| Category 7: Products applied to the hair with some hand contact |
Category 7A: Rinse-off products applied to the hair with some hand contact |
4.80 % |
Category 7B: Leave-on products applied to the hair with some hand contact |
4.80 % |
Category 8: Products with significant anogenital exposure |
0.20 % |
Category 9: Products with body and hand exposure, primarily rinse off |
4.60 % |
| Category 10: Household care products with mostly hand contact |
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products) |
4.60 % |
Category 10B: Household aerosol/spray products |
17.00 % |
| Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate |
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure |
0.20 % |
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure |
0.20 % |
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin |
No Restriction |
| Notes: |
IFRA FLAVOR REQUIREMENTS: |
Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards. |
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 73.00 (μg/capita/day) |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | - | 1.50000 |
beverages(nonalcoholic): | - | 0.27000 |
beverages(alcoholic): | - | 0.50000 |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 0.68000 |
fruit ices: | - | 0.68000 |
gelatins / puddings: | - | 0.10000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 1.40000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s): |
The FEMA GRAS assessment of lactones used as flavor ingredients. View pdf |
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to - Flavouring Group Evaluation 10: Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf |
Flavouring Group Evaluation 10, Revision 1 (FGE10 Rev1)[1] - Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 64 (FGE.64): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (57th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 evaluated by EFSA in FGE.10Rev1 (EFSA, 2008ab) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 92 (FGE.92): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (68th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones evaluated by EFSA in FGE.10Rev1 (2009) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 10, Revision 2 (FGE.10Rev2): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 View page or View pdf |
Safety of 31 flavouring compounds belonging to different chemical groups when used as feed additives for all animal species View page or View pdf |
EPI System: | View |
Chemical Carcinogenesis Research Information System: | Search |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 106-02-5 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 235414 |
National Institute of Allergy and Infectious Diseases: | Data |
WISER: | UN 3077 |
WGK Germany: | 1 |
| 16-oxacyclohexadecan-1-one |
Chemidplus: | 0000106025 |
RTECS: | RN9775000 for cas# 106-02-5 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
15- | angelica lactone | | cyclo penta decanolide | 16-oxa | cyclohexadecan-1-one | oxa | cyclohexadecan-2-one | 1-oxa-2- | cyclohexadecanone | | exaltex | | exaltolide (Firmenich) | | hexaltolide | 15- | hydroxypentadecanoic acid e-lactone | 15- | hydroxypentadecanoic acid lactone | 15- | hydroxypentadecanoic acid omega-lactone | 15- | hydroxypentadecanoic acid, lactone | | macrolide (Symrise) | | macrolide non-FEMA | | macrolide supra (Symrise) | | muscolactone | | muskalactone | | muskolactone | 2- | pentadecalone | | pentadecan-15-olide | | pentadecane-15-olide | | pentadecano-1,15-lactone | 15- | pentadecanolactone | | pentadecanolid | 1,15- | pentadecanolide | 15- | pentadecanolide | | pentalide (Bedoukian) | | pentalide (cyclopentadecanolide) | 14-oxy | tetradecane carbonic acid lactone | | thibetolide |
Articles:
Google Patents: | Preparation of cyclopentadecanolide |
PubMed: | Exploring the Solid State Properties of Enzymatic Poly(amine-co-ester) Terpolymers to Expand their Applications in Gene Transfection. |
Google Patents: | Process for the preparation of cyclopentadecanolide |
PubMed: | Method for preparation, programming, and characterization of miniaturized particulate shape-memory polymer matrices. |
PubMed: | Micelles of enzymatically synthesized PEG-poly(amine-co-ester) block copolymers as pH-responsive nanocarriers for docetaxel delivery. |
PubMed: | Evaluation of PEG and mPEG-co-(PGA-co-PDL) microparticles loaded with sodium diclofenac. |
PubMed: | Characterization of CpdC, a large-ring lactone-hydrolyzing enzyme from Pseudomonas sp. strain HI-70, and its use as a fusion tag facilitating overproduction of proteins in Escherichia coli. |
PubMed: | Multifunctional hybrid nanocomposites with magnetically controlled reversible shape-memory effect. |
PubMed: | Evaluation of biodegradable polyester-co-lactone microparticles for protein delivery. |
PubMed: | Treatment of lung cancer using nanoparticle drug delivery systems. |
PubMed: | Dry powder inhalation of macromolecules using novel PEG-co-polyester microparticle carriers. |
PubMed: | Upscaling the synthesis of biodegradable multiblock copolymers capable of a shape-memory effect. |
PubMed: | Fragrance material review on ω-pentadecalactone. |
PubMed: | Biodegradation, biocompatibility, and drug delivery in poly(ω-pentadecalactone-co-p-dioxanone) copolyesters. |
PubMed: | Poly(glycerol adipate-co-ω-pentadecalactone) spray-dried microparticles as sustained release carriers for pulmonary delivery. |
PubMed: | Lipase-catalyzed copolymerization of dialkyl carbonate with 1,4-butanediol and ω-pentadecalactone: synthesis of poly(ω-pentadecalactone-co-butylene-co-carbonate). |
PubMed: | One-way and reversible dual-shape effect of polymer networks based on polypentadecalactone segments. |
PubMed: | Electrospun scaffolds of a polyhydroxyalkanoate consisting of omega-hydroxylpentadecanoate repeat units: fabrication and in vitro biocompatibility studies. |
PubMed: | Synthesis of omega-hydroxy carboxylic acids and alpha,omega-dimethyl ketones using alpha,omega-diols as alkylating agents. |
PubMed: | Preparation and evaluation of microspheres prepared from novel polyester-ibuprofen conjugates blended with non-conjugated ibuprofen. |
PubMed: | Poly(omega-pentadecalactone-co-butylene-co-succinate) nanoparticles as biodegradable carriers for camptothecin delivery. |
PubMed: | Scaffold for tissue engineering fabricated by non-isothermal supercritical carbon dioxide foaming of a highly crystalline polyester. |
PubMed: | Lipase-catalyzed synthesis of aliphatic polyesters via copolymerization of lactone, dialkyl diester, and diol. |
PubMed: | Synthesis and evaluation of novel polyester-ibuprofen conjugates for modified drug release. |
PubMed: | New oxa-bridged macrocycles. |
PubMed: | Encapsulation and release of alpha-chymotrypsin from poly(glycerol adipate-co-omega-pentadecalactone) microparticles. |
PubMed: | Lipase catalyzed HEMA initiated ring-opening polymerization: in situ formation of mixed polyester methacrylates by transesterification. |
PubMed: | Humicola insolens cutinase-catalyzed lactone ring-opening polymerizations: kinetic and mechanistic studies. |
PubMed: | Lipase-catalyzed copolymerization of omega-pentadecalactone with p-dioxanone and characterization of copolymer thermal and crystalline properties. |
PubMed: | Enzymatic synthesis and evaluation of new novel omega-pentadecalactone polymers for the production of biodegradable microspheres. |
PubMed: | [Analysis of omega-pentadecalactone by thin-layer chromatography]. |
PubMed: | Cocrystallization of random copolymers of omega-pentadecalactone and epsilon-caprolactone synthesized by lipase catalysis. |
PubMed: | Human olfactory contrast changes during the menstrual cycle. |
PubMed: | Macrocyclic musk compounds--an absence of genotoxicity in the Ames test and the in vivo Micronucleus assay. |
PubMed: | Estrogenic activity of musk fragrances detected by the E-screen assay using human mcf-7 cells. |
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