Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless clear liquid (est) |
Assay: | 99.00 to 100.00 %
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Food Chemicals Codex Listed: | Yes |
Specific Gravity: | 0.99600 to 1.00400 @ 25.00 °C.
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Pounds per Gallon - (est).: | 8.288 to 8.354
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Refractive Index: | 1.51000 to 1.51300 @ 20.00 °C.
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Melting Point: | -32.00 °C. @ 760.00 mm Hg
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Boiling Point: | 175.50 °C. @ 760.00 mm Hg
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Vapor Pressure: | 2.029000 mmHg @ 25.00 °C. (est) |
Flash Point: | 128.00 °F. TCC ( 53.33 °C. )
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logP (o/w): | 2.660 |
Shelf Life: | 24.00 month(s) or longer if stored properly. |
Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
Soluble in: |
| alcohol | | dipropylene glycol | | fixed oils | | water, 527.1 mg/L @ 25 °C (est) |
Insoluble in: |
| glycerin | | propylene glycol | | water |
Stability: |
| non-discoloring in most media |
Organoleptic Properties:
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Odor Type: naphthyl |
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Odor Strength: | high , recommend smelling in a 1.00 % solution or less |
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Substantivity: | 8 hour(s) at 100.00 % |
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| naphthyl narcissus ylang powdery nutty |
Odor Description: at 1.00 % in dipropylene glycol. | naphthyl cresol ylang powdery nutty Luebke, William tgsc, (1996) |
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| naphthyl phenolic camphoreous minty powdery nutty |
Odor Description:
| Naphthyl, phenolic, camphoraceous, minty, powdery and nutty Mosciano, Gerard P&F 15, No. 3, 51, (1990) |
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Flavor Type: naphthyl |
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| naphthyl phenolic camphoreous cooling woody |
Taste Description: at 20.00 ppm. | Naphthyl, phenolic, camphoraceous, cooling and woody Mosciano, Gerard P&F 15, No. 3, 51, (1990) |
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Odor and/or flavor descriptions from others (if found). |
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Symrise |
Cresyl methyl ether para |
Odor Description: | strong leather with nuances reminiscent of para-cresol |
Taste Description: | vanilla-, chocolate-, nut-like, slightly phenolic Useful in: fruity red, sweet others. |
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Sigma-Aldrich |
4-Methylanisole, ≥99%, FCC, FG |
Odor Description: | cedar; sweet; vanilla; camphoraceous |
Taste Description: | naphthyl phenolic camphor cooling woody |
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Moellhausen |
METHYL P-CRESOL |
Odor Description: | floreal,camphoraceous, phenolic, in dilution Ylang Ylang, cananga |
Taste Description: | camphoraceous, woody, phenolic, fresh |
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PerfumersWorld |
para-Cresyl methyl ether |
Odor Description: | aromatic-phenolic floral daffodil ylang cananga naphthyl phenolic camphor mint powdery nutty Blends-well-with - +Linalool +Isoamyl Benzyl Ether +Para-tolyl Isobutyrate +Methyl Chavicol +Dimethyl Benzyl Carbinol |
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Cosmetic Information:
Suppliers:
ACS International |
Cresyl Methyl Ether para
Odor: napthyl ylang powdery nutty |
Operational Capabilities |
Augustus Oils |
Para Cresyl Methyl Ether
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Services |
Berjé |
Methyl Para Cresol
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Media |
BOC Sciences |
For experimental / research use only. |
4-Methylanisole
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EMD Millipore |
For experimental / research use only. |
4-Methoxytoluene
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Ernesto Ventós |
para-CRESYL METHYL ETHER
Odor: YLANG YLANG, LEATHER Flavor: VANILLA, NUTS, PHENOLIC |
Indukern F&F |
METHYL PARA-CRESOL
Odor: PHENOLIC, AROMATIC, CAMPHORATED |
Inoue Perfumery |
P-CRESYL METHYL ETHER
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Keva |
PARACRESYL METHYL ETHER
Odor: Pungent, sharp, sweet ylang type |
Lluch Essence |
PARA-CRESYL METHYL ETHER
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Moellhausen |
METHYL P-CRESOL 10%DPG
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Moellhausen |
METHYL P-CRESOL
Odor: floreal,camphoraceous, phenolic, in dilution Ylang Ylang, cananga Flavor: camphoraceous, woody, phenolic, fresh |
Pearlchem Corporation |
p-Cresyl methyl ether
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Penta International |
P-CRESYL METHYL ETHER FCC
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Penta International |
p-CRESYL METHYL ETHER
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PerfumersWorld |
para-Cresyl methyl ether 10% in DPG
|
PerfumersWorld |
para-Cresyl methyl ether
Odor: aromatic-phenolic floral daffodil ylang cananga naphthyl phenolic camphor mint powdery nutty Use: Blends-well-with - +Linalool +Isoamyl Benzyl Ether +Para-tolyl Isobutyrate +Methyl Chavicol +Dimethyl Benzyl Carbinol |
Prodasynth |
PARA-CRESYL METHYL ETHER
(> 98%) Odor: YLANG YLANG, LEATHER Flavor: VANILLA, NUTS, PHENOLIC |
R C Treatt & Co Ltd |
para-Cresyl Methyl Ether
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Reincke & Fichtner |
p-Methylanisole
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Sigma-Aldrich |
4-Methylanisole, ≥99%, FCC, FG
Odor: cedar; sweet; vanilla; camphoraceous |
Certified Food Grade Products |
SRS Aromatics |
METHYL PARA CRESOL
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Taytonn ASCC |
para-Cresyl Methyl Ether
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TCI AMERICA |
For experimental / research use only. |
4-Methoxytoluene >98.0%(GC)
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The Good Scents Company |
para-methyl anisole
Odor: naphthyl cresol ylang powdery nutty |
The John D. Walsh Company |
para-Cresyl Methyl Ether
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The Lermond Company |
PARA CRESYL METHYL ETHER
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The Perfumers Apprentice |
para-cresyl methyl ether
Odor: naphthyl phenolic camphor mint powdery nutty |
U. K. Aromatics and Chemicals |
PARA CRESYL METHYL ETHER
Odor: naphthyl cresol ylang powdery nutty Flavor: Nut, ylang ylang, jasmin |
Ungerer & Company |
Methyl p-Cresol
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Vigon International |
Cresyl Methyl Ether Para FCC
Odor: Pungent sweet, ylang, almond |
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xn - Harmful. |
R 10 - Flammable. R 22 - Harmful if swallowed. R 38 - Irritating to skin. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
Flammable liquids (Category 3), H226 Acute toxicity, Oral (Category 4), H302 Skin irritation (Category 2), H315 Reproductive toxicity (Category 2), H361 Acute aquatic toxicity (Category 3), H402 Chronic aquatic toxicity (Category 3), H412
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GHS Label elements, including precautionary statements |
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Pictogram | |
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Signal word | Warning |
Hazard statement(s) |
H226 - Flammable liquid and vapour H302 - Harmful if swallowed H315 - Causes skin irritation H361 - Suspected of damaging fertility or the unborn child H402 - Harmful to aquatic life H412 - Harmful to aquatic life with long lasting effects
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Precautionary statement(s) |
P201 - Obtain special instructions before use. P202 - Do not handle until all safety precautions have been read and understood. P210 - Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233 - Keep container tightly closed. P240 - Ground/bond container and receiving equipment. P241 - Use explosion-proof electrical/ventilating/lighting/…/equipment. P242 - Use only non-sparking tools. P243 - Take precautionary measures against static discharge. P264 - Wash skin thouroughly after handling. P270 - Do not eat, drink or smoke when using this product. P273 - Avoid release to the environment. P280 - Wear protective gloves/protective clothing/eye protection/face protection. P301 + P312 - IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303 + P361 + P353 - IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P308 + P313 - IF exposed or concerned: Get medical advice/attention. P330 - Rinse mouth. P332 + P313 - IF SKIN irritation occurs: Get medical advice/attention. P362 - Take off contaminated clothing and wash before reuse. P370 + P378 - In case of fire: Use dry sand, dry chemical or alcohol-resistant foam for extinction. P403 + P235 - Store in a well-ventilated place. Keep cool. P405 - Store locked up. P501 - Dispose of contents/ container to an approved waste disposal plant.
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Human Experience: |
2 % solution: no irritation or sensitization. |
Oral/Parenteral Toxicity: |
oral-rat LD50 [sex: M,F] 1920 mg/kg (Wong & Hart, 1971)
intraperitoneal-mouse LD > 500 mg/kg "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 6, Pg. 214, 1954.
oral-rat LD50 1920 mg/kg Food and Cosmetics Toxicology. Vol. 12, Pg. 393, 1974.
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Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 12, Pg. 393, 1974.
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for para-methyl anisole usage levels up to: | | 2.0000 % in the fragrance concentrate.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.49 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 15.00 (μg/capita/day) |
Structure Class: | I |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | - | 7.60000 |
beverages(nonalcoholic): | - | 2.70000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | 2.00000 |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 2.70000 |
fruit ices: | - | 2.70000 |
gelatins / puddings: | 0.50000 | 4.00000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 4.80000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 23 (FGE.23): Aliphatic, alicyclic and aromatic ethers including anisole derivatives From chemical groups 15, 16 and 26 (Commission Regulation (EC) No 1565/2000 of 18 July 2000 View page or View pdf |
Flavouring Group Evaluation 59 (FGE.59): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 (2006) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 23, Revision 1 (FGE.23Rev1): Aliphatic, alicyclic and aromatic ethers including anisole derivatives from chemical groups 15, 16, 26 and 30[1] - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 59, Revision 1 (FGE.59Rev1): Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting and 63rd meeting) structurally related to aliphatic, alicyclic and aromatic ethers including anisole derivatives evaluated by EFSA in FGE.23 Rev2 (2010) View page or View pdf |
Scientific Opinion on the safety and efficacy of aromatic ethers including anisole derivatives (chemical group 26) when used as feed additives for all animal species View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 104-93-8 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 7731 |
National Institute of Allergy and Infectious Diseases: | Data |
WISER: | UN 1993 |
WGK Germany: | 1 |
| 1-methoxy-4-methylbenzene |
Chemidplus: | 0000104938 |
RTECS: | BZ8780000 for cas# 104-93-8 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| anisole, p-methyl- | | benzene, 1-methoxy-4-methyl- | p- | cresol methyl ether | para- | cresol methyl ether | p- | cresyl methyl ether | para- | cresyl methyl ether | p- | cresyl methyl ether ( p – cresol ) | p- | cresyl methyl ether FCC | | cresyl methyl ether para | | cresyl methyl ether para FCC | 1- | methoxy-4-methyl benzene | 1- | methoxy-4-methyl-benzene | 1- | methoxy-4-methylbenzene | 4- | methoxytoluene | p- | methoxytoluene | para- | methoxytoluene | | methyl 4-methyl phenyl ether | | methyl 4-methylphenyl ether | 4- | methyl anisole | p- | methyl anisole | para- | methyl anisole | para- | methyl cresol | | methyl p-cresol | o- | methyl p-cresol | | methyl p-cresyl ether | | methyl p-methylphenyl ether | | methyl p-tolyl ether | | methyl para cresol | ortho- | methyl para-cresol | | methyl para-cresyl ether | | methyl para-methyl phenyl ether | | methyl para-tolyl ether | 4- | methyl phenol methyl ether | 4- | methyl-1-methoxybenzene | 1- | methyl-4-methoxybenzene | | methyl-para-cresol | 4- | methylanisole | p- | methylanisole | para- | methylanisole | 4- | methylcresol | p- | methylcresol | 4- | methylphenol methyl ether | | toluene, 4-methoxy- | p- | tolyl methyl ether | para- | tolyl methyl ether |
Articles:
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