Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | white powder (est) |
Assay: | 95.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Melting Point: | 55.00 to 56.00 °C. @ 760.00 mm Hg
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Boiling Point: | 282.21 °C. @ 760.00 mm Hg (est)
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Vapor Pressure: | 0.002000 mmHg @ 25.00 °C. (est) |
Flash Point: | > 212.00 °F. TCC ( > 100.00 °C. )
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logP (o/w): | 1.050 |
Soluble in: |
| alcohol | | water, 3.047e+004 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
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Odor Type: vanilla |
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| sweet powdery vanilla |
Odor Description: at 100.00 %. | sweet powdery vanilla |
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Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | None - None found. |
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for heliotropyl alcohol usage levels up to: | | 5.0000 % in the fragrance concentrate.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.011 (μg/capita/day) |
Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 3900 (μg/person/day) |
Threshold of Concern: | 540 (μg/person/day) |
Structure Class: | II |
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Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). |
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. |
| average usage mg/kg | maximum usage mg/kg |
Dairy products, excluding products of category 02.0 (01.0): | 7.00000 | 35.00000 |
Fats and oils, and fat emulsions (type water-in-oil) (02.0): | 5.00000 | 25.00000 |
Edible ices, including sherbet and sorbet (03.0): | 10.00000 | 50.00000 |
Processed fruit (04.1): | 7.00000 | 35.00000 |
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | - | - |
Confectionery (05.0): | 10.00000 | 50.00000 |
Chewing gum (05.0): | - | - |
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 5.00000 | 25.00000 |
Bakery wares (07.0): | 10.00000 | 50.00000 |
Meat and meat products, including poultry and game (08.0): | 2.00000 | 10.00000 |
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | 2.00000 | 10.00000 |
Eggs and egg products (10.0): | - | - |
Sweeteners, including honey (11.0): | - | - |
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | 5.00000 | 25.00000 |
Foodstuffs intended for particular nutritional uses (13.0): | 10.00000 | 50.00000 |
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | 5.00000 | 25.00000 |
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | 10.00000 | 50.00000 |
Ready-to-eat savouries (15.0): | 20.00000 | 100.00000 |
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 5.00000 | 25.00000 |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23 View page or View pdf |
Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 54 (FGE.54)[1] - Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20 (2005) - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf |
Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23 View page or View pdf |
Flavouring Group Evaluation 54, Revision 1 (FGE.54Rev1): Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20Rev1 (2009) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 4 (FGE.20Rev4): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 495-76-1 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 10322 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 3 |
| 1,3-benzodioxol-5-ylmethanol |
Chemidplus: | 0000495761 |
References:
Other Information:
Potential Blenders and core components note
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For Odor |
No odor group found for these |
alpha- | acorenol | |
acidic |
| cyclohexyl acetic acid | FL/FR |
amber |
| amber powdery floral fragrance | FR |
| ambrette seed oil | FL/FR |
anisic |
ortho- | acetanisole | FL/FR |
para- | acetanisole | FL/FR |
ortho- | anisaldehyde | FL/FR |
para- | anisaldehyde | FL/FR |
balsamic |
| benzoin | FL/FR |
sumatra | benzoin absolute | FL/FR |
siam | benzoin absolute | FL/FR |
| benzoin resin replacer | FR |
siam | benzoin resinoid | FL/FR |
sumatra | benzoin resinoid | FL/FR |
| benzophenone | FR |
1- | benzoyl acetone | FL/FR |
| benzyl cinnamate | FL/FR |
iso | butyl benzoate | FL/FR |
| cinnamyl alcohol | FL/FR |
| ethyl cinnamate | FL/FR |
| peru balsam absolute | FL/FR |
| peru balsam oil | FL/FR |
| peru balsam resinoid | FL/FR |
chocolate |
| chocolate specialty | FR |
| cocoa pentenal | FL/FR |
| vanillyl ethyl ether | FL/FR |
coumarinic |
| coumane | FL/FR |
| phthalide | FL/FR |
creamy |
para- | vanillic acid | FL/FR |
para- | vanillyl alcohol | FL/FR |
| veratraldehyde | FL/FR |
floral |
para- | anisaldehyde / methyl anthranilate schiff's base | FR |
| anisyl propanal / methyl anthranilate schiff's base | FR |
para- | cresyl laurate | FL/FR |
para- | cresyl propionaldehyde | CS |
| dimethyl alpha-ionone | FR |
| dimethyl anthranilate | FL/FR |
| geranyl phenyl acetate | FL/FR |
| hawthorn acetate | FR |
| heliotropin | FL/FR |
| heliotropyl acetone | FL/FR |
(E)-beta- | ionone | FL/FR |
alpha- | irone | FL/FR |
ortho- | methyl acetophenone | FL/FR |
beta-iso | methyl ionone | FL/FR |
alpha-iso | methyl ionone (50% min.) | FL/FR |
alpha-iso | methyl ionone (90% min.) | FL/FR |
| methyl ionyl acetate | FL/FR |
| mimosa absolute replacer | FR |
| orris rhizome resinoid (iris pallida) | FL/FR |
| petitgrain mandarin oil terpeneless | FL/FR |
4- | phenyl-2-butanol | FL/FR |
iso | propyl phenyl acetate | FL/FR |
| rhodinol | FL/FR |
| rhodinyl acetate | FL/FR |
| rhodinyl phenyl acetate | FL/FR |
(E)-2,5,9- | trimethyl-4,9-decadien-1-al | FR |
fruity |
| acetyl methyl anthranilate | FL/FR |
| berry hexanoate | FR |
| cherry oxyacetate | FL/FR |
| ethyl methyl-para-tolyl glycidate | FL/FR |
| peach pivalate | FR |
| prenyl acetate | FL/FR |
| tolualdehydes (mixed o,m,p) | FL/FR |
| vanilla carboxylate | FL/FR |
green |
para- | methyl hydratropaldehyde | FL/FR |
| phenoxyethyl isobutyrate | FL/FR |
minty |
| menthoxypropane diol | FL/FR |
| vanillin menthoxypropane diol acetal | FL/FR |
musk |
| cyclohexadecanone | FR |
| ethylene brassylate | FL/FR |
| exaltone (Firmenich) | FR |
dextro,laevo- | muscone | FL/FR |
| musk amberol | FR |
| musk indane | FR |
| musk indanone | FR |
| musk tetralin | FL/FR |
omega- | pentadecalactone | FL/FR |
6,7,8,9- | tetrahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline | FR |
musty |
| cocoa butenal | FL/FR |
naphthyl |
2,4- | dimethyl benzaldehyde | FL/FR |
para- | methyl anisole | FL/FR |
beta- | naphthyl ethyl ether | FL/FR |
nutty |
2,3,5- | trimethyl pyrazine | FL/FR |
phenolic |
| ethyl vanillate | FL/FR |
ortho- | guaiacol | FL/FR |
powdery |
para- | anisyl acetate | FL/FR |
para- | anisyl alcohol | FL/FR |
alpha- | methyl ionone | FL/FR |
smoky |
alpha- | ethoxy-ortho-cresol | FL/FR |
spicy |
para- | anisyl formate | FL/FR |
| dianthus ethone | FR |
(E)-para- | methoxycinnamaldehyde | FL/FR |
para- | methoxycinnamaldehyde | FL/FR |
4- | methyl guaiacol | FL/FR |
| zingerone | FL/FR |
sweet |
| vanilla resinoid | FL/FR |
tobacco |
| methyl benzoxole | FL/FR |
tonka |
| coumarin | FR |
vanilla |
| acetovanillone | FL/FR |
ortho- | dimethyl hydroquinone | FL/FR |
| ethyl vanillin | FL/FR |
| ethyl vanillin isobutyrate | FL/FR |
| ethyl vanillin propylene glycol acetal | FL/FR |
| methyl vanillate | FL/FR |
| propenyl guaethol | FL/FR |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
| vanilla cresol | FR |
| vanillin | FL/FR |
| vanillin 2,3-butylene glycol acetal | FL/FR |
| vanillin propylene glycol acetal | FL/FR |
| vanillyl acetate | FL/FR |
| vanillyl butyl ether | FL/FR |
| vanillyl isobutyrate | FL/FR |
| vanillylidene acetone | FL/FR |
woody |
| amber formate | FR |
| guaiacwood oil | FL/FR |
| guaiacyl acetate | FL/FR |
| sandal pentenone | FR |
(+)-alpha- | santalyl acetate | FL/FR |
| timber propanol | FR |
4,6,11- | trimethyl-5-oxatricyclo(6.2.2.0*4,9*)dodec-6-ene | FR |
| vetiveryl acetate | FL/FR |
| woody epoxide | FR |
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For Flavor |
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No flavor group found for these |
alpha- | acorenol | |
| benzoin | FL/FR |
1- | benzoyl acetone | FL/FR |
| coumane | FL/FR |
ortho- | dimethyl hydroquinone | FL/FR |
alpha- | ethoxy-ortho-cresol | FL/FR |
| glucoethyl vanillin | FL |
| menthoxypropane diol | FL/FR |
(E)-para- | methoxycinnamaldehyde | FL/FR |
4- | methoxysalicylaldehyde | FL |
beta-iso | methyl ionone | FL/FR |
| methyl vanillate | FL/FR |
(+)-alpha- | santalyl acetate | FL/FR |
| vanillin menthoxypropane diol acetal | FL/FR |
| vanillyl butyl ether | FL/FR |
| vetiveryl acetate | FL/FR |
amber |
| ambrette seed oil | FL/FR |
| musk tetralin | FL/FR |
anisic |
para- | acetanisole | FL/FR |
ortho- | anisaldehyde | FL/FR |
ortho- | methyl acetophenone | FL/FR |
balsamic |
siam | benzoin resinoid | FL/FR |
sumatra | benzoin resinoid | FL/FR |
| ethyl cinnamate | FL/FR |
| peru balsam absolute | FL/FR |
| peru balsam oil | FL/FR |
| peru balsam resinoid | FL/FR |
| vanillylidene acetone | FL/FR |
berry |
| heliotropyl acetone | FL/FR |
cherry |
| heliotropin | FL/FR |
para- | methoxycinnamaldehyde | FL/FR |
coconut |
6- | methyl coumarin | FL |
coumarinic |
| phthalide | FL/FR |
creamy |
para- | anisaldehyde | FL/FR |
| divanillin | FL |
| ethyl vanillate | FL/FR |
para- | vanillic acid | FL/FR |
para- | vanillyl alcohol | FL/FR |
| veratraldehyde | FL/FR |
floral |
| cocoa pentenal | FL/FR |
| geranyl phenyl acetate | FL/FR |
pseudo | ionone | FL |
alpha-iso | methyl ionone (50% min.) | FL/FR |
alpha-iso | methyl ionone (90% min.) | FL/FR |
| orris rhizome resinoid (iris pallida) | FL/FR |
4- | phenyl-2-butanol | FL/FR |
| rhodinol | FL/FR |
| rhodinyl acetate | FL/FR |
fruity |
| acetyl methyl anthranilate | FL/FR |
para- | anisyl acetate | FL/FR |
para- | anisyl alcohol | FL/FR |
iso | butyl benzoate | FL/FR |
| cherry oxyacetate | FL/FR |
| dimethyl anthranilate | FL/FR |
| ethyl methyl-para-tolyl glycidate | FL/FR |
alpha- | methyl ionone | FL/FR |
| petitgrain mandarin oil terpeneless | FL/FR |
| prenyl acetate | FL/FR |
| tolualdehydes (mixed o,m,p) | FL/FR |
| vanilla carboxylate | FL/FR |
green |
| cinnamyl alcohol | FL/FR |
| cocoa butenal | FL/FR |
para- | methyl hydratropaldehyde | FL/FR |
| phenoxyethyl isobutyrate | FL/FR |
honey |
iso | propyl phenyl acetate | FL/FR |
meaty |
ortho- | thioguaiacol | FL |
musk |
| ethylene brassylate | FL/FR |
dextro,laevo- | muscone | FL/FR |
musty |
2,3,5- | trimethyl pyrazine | FL/FR |
naphthyl |
2,4- | dimethyl benzaldehyde | FL/FR |
para- | methyl anisole | FL/FR |
nutty |
| furfural acetone | FL |
| methyl benzoxole | FL/FR |
powdery |
ortho- | acetanisole | FL/FR |
beta- | naphthyl ethyl ether | FL/FR |
| powdery ketone | FL |
rummy |
| vanillyl ethyl ether | FL/FR |
spicy |
para- | anisyl formate | FL/FR |
sumatra | benzoin absolute | FL/FR |
siam | benzoin absolute | FL/FR |
| benzyl cinnamate | FL/FR |
4- | methyl guaiacol | FL/FR |
| zingerone | FL/FR |
sweet |
| cyclohexyl acetic acid | FL/FR |
| vanilla resinoid | FL/FR |
vanilla |
| acetovanillone | FL/FR |
| ethyl vanillin | FL/FR |
| ethyl vanillin isobutyrate | FL/FR |
| ethyl vanillin propylene glycol acetal | FL/FR |
omega- | pentadecalactone | FL/FR |
| propenyl guaethol | FL/FR |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
| vanillin | FL/FR |
| vanillin 2,3-butylene glycol acetal | FL/FR |
| vanillin propylene glycol acetal | FL/FR |
| vanillyl acetate | FL/FR |
| vanillyl isobutyrate | FL/FR |
waxy |
para- | cresyl laurate | FL/FR |
| rhodinyl phenyl acetate | FL/FR |
woody |
ortho- | guaiacol | FL/FR |
| guaiacwood oil | FL/FR |
| guaiacyl acetate | FL/FR |
(E)-beta- | ionone | FL/FR |
alpha- | irone | FL/FR |
| methyl ionyl acetate | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| benzo(1,3)dioxol-5-yl methanol | 2H- | benzo[3,4-d]1,3-dioxolan-5-ylmethan-1-ol | | benzo[d][1,3]dioxol-5-ylmethanol | (1,3- | benzodioxol-5-yl)methanol | 1,3- | benzodioxol-5-ylmethanol | 1,3- | benzodioxole-5-methanol | | benzyl alcohol, 3,4-(methylenedioxy)- | | heliotropin alcohol | 5- | hydroxymethyl-1,3-benzodioxole | 1- | hydroxymethyl-3,4-methylene dioxybenzene | 1- | hydroxymethyl-3,4-methylenedioxybenzene | 3,4-( | methylene dioxy) benzyl alcohol | 3,4-( | methylene dioxy) phenyl methanol | 3,4-( | methylenedioxy)phenylmethanol | 3,4- | methylenedioxybenzyl alcohol | | piperonal alcohol | | piperonol | | piperonyl alcohol |
Articles:
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