Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless to pale yellow clear liquid (est) |
Assay: | 95.00 to 100.00 %
|
Food Chemicals Codex Listed: | Yes |
Specific Gravity: | 0.81500 to 0.81700 @ 25.00 °C.
|
Pounds per Gallon - (est).: | 6.782 to 6.798
|
Refractive Index: | 1.41400 to 1.41700 @ 20.00 °C.
|
Melting Point: | -16.00 to -15.00 °C. @ 760.00 mm Hg
|
Boiling Point: | 173.00 to 175.00 °C. @ 760.00 mm Hg
|
Boiling Point: | 94.00 to 95.00 °C. @ 50.00 mm Hg
|
Acid Value: | 1.00 max. KOH/g
|
Vapor Pressure: | 1.725000 mmHg @ 25.00 °C. (est) |
Vapor Density: | 4.4 ( Air = 1 ) |
Flash Point: | 145.00 °F. TCC ( 62.78 °C. )
|
logP (o/w): | 2.370 |
Soluble in: |
| alcohol | | water, 900 mg/L @ 20 °C (exp) |
Organoleptic Properties:
|
Odor Type: earthy |
|
Odor Strength: | medium , recommend smelling in a 10.00 % solution or less |
|
Substantivity: | > 4 hour(s) at 100.00 % |
|
| earthy weedy natural woody herbal |
Odor Description: at 10.00 % in dipropylene glycol. | earthy weedy natural woody herbal |
|
| musty ketonic cheesy bleu cheese cheesy parmesan cheese earthy dairy |
Odor Description:
| Musty, ketonic, bleu and parmesan cheese-like with earthy and dairy nuances Mosciano, Gerard P&F 21, No. 1, 33, (1996) |
|
|
Flavor Type: dairy |
|
| dairy waxy cheesy woody mushroom yeasty |
Taste Description: at 10.00 ppm. | Dairy, waxy, cheese, woody, mushroom and yeast Mosciano, Gerard P&F 21, No. 1, 33, (1996) |
|
Odor and/or flavor descriptions from others (if found). |
|
Bedoukian Research |
METHYL HEXYL KETONE ≥97.5%, FCC, Kosher |
Odor Description: | sweet, earthy, weedy, 'natural' An interesting note for lilac compositions. |
Taste Description: | Ketonic, fermented notes Adds ketonic notes for a variety of cheese flavors, unroasted nuts especially hazelnut and cashews. |
|
Moellhausen |
2-OCTANONE |
Odor Description: | floral, green, herbaceous, fruity |
Taste Description: | cheesy, sharp, ketonic (waxy note) |
|
Firmenich |
2-OCTANONE min. 98%, Kosher for flavor |
Taste Description: | Intense blue cheese, fruity, mushroom and green notes 2-OCTANONE adds nice fruity, blue and parmesan cheese-like notes with mushroom and dairy nuances to dairy, fruit and cooked meat flavors. |
|
PerfumersWorld |
Methyl hexyl ketone |
Odor Description: | sweet earthy weedy natural woody herbal green fruity wine floral green herbaceous fruity Blends-well-with - +2-heptanone Herbaceous-notes |
|
Nagar Haveli Perfumes & Aromatics |
Methyl Hexyl Ketone Natural |
Odor Description: | Musty, ketonic, bleu and parmesan cheese-like with earthy and dairy nuances |
|
|
Cosmetic Information:
Suppliers:
Advanced Biotech |
2-OCTANONE NATURAL
98% min. Odor: Camphor, Bitter |
Alfrebro |
METHYL HEXYL KETONE NATURAL
Odor: Floral, Green, Herbaceous, Fruity |
Associate Allied Chemicals |
Methyl Hexyl Ketone
|
About |
Augustus Oils |
Methyl Hexyl Ketone
|
Services |
Aurochemicals |
2-OCTANONE, Natural
|
Axxence Aromatic |
METHYL HEXYL KETONE Natural
Kosher |
Sustainability |
Bedoukian Research |
METHYL HEXYL KETONE
≥97.5%, FCC, Kosher Odor: sweet, earthy, weedy, 'natural' Use: An interesting note for lilac compositions. Flavor: Ketonic, fermented notes Adds ketonic notes for a variety of cheese flavors, unroasted nuts especially hazelnut and cashews. |
Berjé |
Methyl Hexyl Ketone
|
Media |
BOC Sciences |
For experimental / research use only. |
METHYL HEXYL KETONE FCC 97.5%
|
CJ Latta & Associates |
2-OCTANONE
|
Diffusions Aromatiques |
2-OCTANONE
|
Diffusions Aromatiques |
2-OCTANONE
|
Ernesto Ventós |
METHYL HEXYL KETONE
Odor: GREEN,CAMPHOR,LAVENDER,FATTY |
Excellentia International |
Methyl Hexyl Ketone (2-Octanone) Natural
|
Firmenich |
2-OCTANONE min. 98%, Kosher
for flavor Flavor: Intense blue cheese, fruity, mushroom and green notes 2-OCTANONE adds nice fruity, blue and parmesan cheese-like notes with mushroom and dairy nuances to dairy, fruit and cooked meat flavors. |
fnfsurplus.com |
2-Octanone
|
Global Essence |
Methyl hexyl ketone
|
Indukern F&F |
METHYL HEXYL KETONE ( LAVENTERRE )
Odor: FRUITY, EARTHY, MUSHROOM |
Indukern F&F |
METHYL HEXYL KETONE
Odor: GREEN, HERBAL, FRUITY |
Inoue Perfumery |
HEXYL METHYL KETONE
|
Kingchem Laboratories |
2 OCTANONE
|
Lluch Essence |
METHYL HEXYL KETONE NATURAL
|
Lluch Essence |
METHYL HEXYL KETONE
|
M&U International |
-METHYL HEXYL KETONE, Kosher
|
Moellhausen |
2-OCTANONE
Odor: floral, green, herbaceous, fruity Flavor: cheesy, sharp, ketonic (waxy note) |
Nagar Haveli Perfumes & Aromatics |
Methyl Hexyl Ketone
Natural Odor: Musty, ketonic, bleu and parmesan cheese-like with earthy and dairy nuances |
Odowell Co.,ltd |
Methyl hexyl ketone
PURITY: 99%min. |
Penta International |
METHYL HEXYL KETONE NATURAL
|
Penta International |
METHYL HEXYL KETONE PURE
|
PerfumersWorld |
Methyl hexyl ketone
Odor: sweet earthy weedy natural woody herbal green fruity wine floral green herbaceous fruity Use: Blends-well-with - +2-heptanone Herbaceous-notes |
R C Treatt & Co Ltd |
2-Octanone
|
Reincke & Fichtner |
2-Octanone
|
Seqens |
Methyl Hexyl Ketone, Kosher
|
Sigma-Aldrich |
2-Octanone, ≥98%, FG
Odor: green; herbaceous; floral; fruity |
Certified Food Grade Products |
Sigma-Aldrich |
2-Octanone, natural, 98%, FG
|
SRS Aromatics |
METHYL HEXYL KETONE (FG)
|
SRS Aromatics |
METHYL HEXYL KETONE
|
Synerzine |
2-Octanone
|
Taytonn ASCC |
Ketone C-8
Odor: Bitter, Floral, Fruity, Green, Herbal/ Herbaceous, Musk/ Musky |
TCI AMERICA |
For experimental / research use only. |
2-Octanone >98.0%(GC)
|
The John D. Walsh Company |
Methyl Hexyl Ketone
|
The Lermond Company |
METHYL HEXYL KETONE
|
The Perfumers Apprentice |
Methyl Hexyl Ketone
Odor: earthy weedy woody herbal |
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xn - Harmful. |
R 21 - Harmful in contact with skin. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 20/21 - When using do not eat, drink or smoke. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
|
|
Hazards identification |
|
Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
|
Pictogram | |
|
Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Human Experience: |
4 % solution: no irritation or sensitization. |
Oral/Parenteral Toxicity: |
oral-rat LD50 > 5000 mg/kg (Katz et al., 1980)
oral-mouse LD50 [sex: M] 3823 mg/kg (Tanii et al., 1986)
oral-mouse LD50 3870 mg/kg (Tanii et al., 1986)
intraperitoneal-mouse LD50 800 mg/kg "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4765, 1982.
oral-mouse LD50 3824 mg/kg Toxicology Letters. Vol. 30, Pg. 13, 1986.
unreported-mouse LD50 1600 mg/kg Journal of Medicinal Chemistry. Vol. 19, Pg. 1257, 1976.
intraperitoneal-rat LD50 800 mg/kg "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4765, 1982.
oral-rat LD50 3089 mg/kg Kodak Company Reports. Vol. #901875
|
Dermal Toxicity: |
skin-rabbit LD50 1337 mg/kg Kodak Company Reports. Vol. #901875
|
Inhalation Toxicity: |
inhalation-rat LC50 2132 ppm/6hours KODAK* #901875
inhalation-rat LC50 > 2132 ppm/6H Kodak Company Reports. Vol. #901875
|
Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for 2-octanone usage levels up to: | | 4.0000 % in the fragrance concentrate.
|
|
Maximised Survey-derived Daily Intakes (MSDI-EU): | 93.00 (μg/capita/day) |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | 0.40000 | 4.00000 |
beverages(nonalcoholic): | 0.10000 | 1.00000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | 0.20000 | 1.00000 |
fruit ices: | 0.20000 | 1.00000 |
gelatins / puddings: | - | - |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | 0.40000 | 4.00000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 7 (FGE.07): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5 View page or View pdf |
Flavouring Group Evaluation 7, Revision 1 (FGE.07Rev1): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission View page or View pdf |
Flavouring Group Evaluation 7, Revision 2 (FGE.07Rev2) : Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5 View page or View pdf |
Safety and efficacy of saturated and unsaturated aliphatic secondary alcohols, ketones and esters with esters containing secondary alcohols belonging to chemical group 5 when used as flavourings for all animal species View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 111-13-7 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 8093 |
National Institute of Allergy and Infectious Diseases: | Data |
WISER: | UN 1224 |
WGK Germany: | 1 |
| octan-2-one |
Chemidplus: | 0000111137 |
RTECS: | RH1484000 for cas# 111-13-7 |
References:
Other Information:
Potential Blenders and core components note
|
For Odor |
acidic |
acidic |
iso | butyric acid | FL/FR |
| cyclohexyl acetic acid | FL/FR |
2- | methyl butyric acid | FL/FR |
aldehydic |
| acetyl nonyryl | FL/FR |
amber |
| angelica archangelica root oil CO2 extract | FL/FR |
1-oxa | spiro-4,7-dodecane | FR |
balsamic |
dextro,laevo-iso | borneol | FL/FR |
iso | bornyl propionate | FL/FR |
| cedar forest fragrance | FR |
| conifer acetate | FR |
buttery |
| acetyl propionyl | FL/FR |
| butyl butyryl lactate | FL/FR |
2,3- | heptane dione | FL/FR |
camphoreous |
dextro- | camphor | FL/FR |
cheesy |
| butyric acid | FL/FR |
| heptanoic acid | FL/FR |
2- | methyl hexanoic acid | FL/FR |
S-( | methyl thio) butyrate | FL/FR |
2- | methyl valeric acid | FL/FR |
2- | methyl-2-hexenoic acid | FR |
citrus |
| neroli ketone | FR |
| hexanoic acid | FL/FR |
floral |
| aglaia odorata absolute | FR |
| bigarade oxide | FR |
| ho leaf oil | FR |
| karo karounde absolute | FR |
| karo karounde absolute replacer | FR |
| petitgrain bigarade oil | FL/FR |
| sambucus nigra flower oil CO2 extract | FR |
5- | tricyclodecenyl acetate | FR |
fruity |
3- | benzyl-4-heptanone | FL/FR |
| cyclohexyl carboxylic acid | FL/FR |
| filbert hexenone | FL/FR |
4- | heptanone | FL/FR |
| methyl 4-methyl valerate | FL/FR |
2- | methyl butyl isovalerate | FL/FR |
2- | nonanone | FL/FR |
| prenyl hexanoate | FL/FR |
| sorbyl butyrate | FL/FR |
fungal |
1- | decen-3-ol | FL/FR |
green |
iso | cyclocitral (IFF) | FL/FR |
| dicyclopentadiene propionate | FR |
| fragaria vesca leaf absolute | FR |
| galbascone (IFF) | FR |
(E)-2- | hexenal | FL/FR |
alpha- | hexyl cinnamaldehyde dimethyl acetal | FR |
para- | methyl hydratropaldehyde | FL/FR |
hay |
| tobacco leaf absolute | FL/FR |
herbal |
1- | allyl-2,2,7,7-tetramethyl cycloheptanol | FR |
| angelica archangelica seed extract | FL/FR |
| artemisia vestita wall. leaf oil | FR |
| bornyl 2-methyl butyrate | FL/FR |
| bornyl butyrate | FL/FR |
beta- | bourbonene | FL/FR |
| calamintha clinopodium oil | FR |
| cardamom liquid resin | FR |
| dill seed oil | FL/FR |
| dill seed oil CO2 extract | FL/FR |
| herbal ketone | FR |
| herbal undecanone | FR |
| immortelle flower oil | FL/FR |
| lavandin water absolute | FL/FR |
2- | methyl butyl salicylate | FL/FR |
1- | octen-3-yl acetate | FL/FR |
alpha- | pinene | FL/FR |
| pinocarveol | FL/FR |
| thyme oil wild or creeping | FL/FR |
minty |
| nepeta cataria herb oil | FR |
| pennyroyal oil | FL/FR |
musk |
| angelica root absolute | FL/FR |
nutty |
| nutty quinoxaline | FL/FR |
| pentanoic acid, 3-methyl-2-oxo-, ethyl ester | FL/FR |
oily |
| butter acids | FL/FR |
orris |
para-iso | propyl acetophenone | FL/FR |
spicy |
| bayberry fragrance | FR |
| cardamom seed oil CO2 extract | FL/FR |
| cinnamon acrolein | FL/FR |
| ginger oleoresin africa | FL/FR |
| ginger root absolute | FL/FR |
| ginger root oil cochin | FL/FR |
| maja fragrance | FR |
| myrcene | FR |
2- | octanol | FL/FR |
black | pepper absolute | FL/FR |
black | pepper oil | FL/FR |
white | pepper oil | FL/FR |
black | pepper oleoresin | FL/FR |
4-iso | propyl-2-cyclohexenone | FL/FR |
thujonic |
| cedarleaf oil western red | FR |
common | tansy flower oil argentina | FL/FR |
common | tansy leaf oil dutch | FR |
| woody ketone | FL/FR |
waxy |
5(6)- | decenoic acid | FL/FR |
2- | methyl heptanoic acid | FL/FR |
| nonanoic acid | FL/FR |
2- | nonanol | FL/FR |
| undecanoic acid | FL/FR |
woody |
| angelica archangelica root extract | FL/FR |
| angelica archangelica root tincture | FL/FR |
| angelica archangelica root water | FL/FR |
| cadinene | FL/FR |
(+)- | camphene | FL/FR |
| camphene | FL/FR |
| cypress essence | FR |
| dalbergia sissoo leaf oil | FR |
| dihydro-alpha-terpinyl acetate | FR |
| fougere woody fragrance | FR |
(1R,4S)-1- | hydroxy-1,4-dimethyl spiro(4.6)undecan-2-one | |
| laitone | FR |
| manevoro oil | FR |
| marine formate | FR |
| melaleuca bracteata leaf oil | FR |
gamma- | muurolene | |
| origanum vulgare ssp. vulgare oil himalaya | |
| patchouli fragrance | FR |
| patchouli oil | FL/FR |
| patchouli oil CO2 extract | FL/FR |
| patchouli oil decolorized | FL/FR |
| patchouli oil molecular distilled | FL/FR |
| patchouli oil replacer | FR |
| patchouli specialty | FR |
| polylimonene | FL/FR |
| santol pentenol | FR |
| tetrahydromugol | FR |
|
For Flavor |
|
No flavor group found for these |
| angelica archangelica root extract | FL/FR |
| angelica archangelica root oil CO2 extract | FL/FR |
| angelica archangelica root tincture | FL/FR |
| angelica archangelica root water | FL/FR |
| bornyl 2-methyl butyrate | FL/FR |
| bornyl butyrate | FL/FR |
beta- | bourbonene | FL/FR |
delta- | cadinene | FL |
(+)- | camphene | FL/FR |
| ethyl cyclohexyl carboxylate | FL |
(E,E)-2,4- | heptadien-1-ol | FL |
(Z)-3- | hexenoic acid | FL |
(1R,4S)-1- | hydroxy-1,4-dimethyl spiro(4.6)undecan-2-one | |
2- | methyl butyl salicylate | FL/FR |
5- | methyl hexanoic acid | FL |
1- | methyl pyrrole | FL |
4- | methyl valeric acid | FL |
gamma- | muurolene | |
| origanum vulgare ssp. vulgare oil himalaya | |
| polylimonene | FL/FR |
| prenyl hexanoate | FL/FR |
4-iso | propyl-2-cyclohexenone | FL/FR |
| woody ketone | FL/FR |
acidic |
iso | butyric acid | FL/FR |
aldehydic |
| acetyl nonyryl | FL/FR |
balsamic |
iso | bornyl propionate | FL/FR |
buttery |
| butter crème flavor | FL |
creamy | butter flavor | FL |
2,3- | heptane dione | FL/FR |
2- | methyl valeric acid | FL/FR |
(E)-2- | pentenoic acid | FL |
camphoreous |
dextro,laevo-iso | borneol | FL/FR |
| camphene | FL/FR |
| pinocarveol | FL/FR |
| hexanoic acid | FL/FR |
2- | nonanone | FL/FR |
citrus |
| petitgrain bigarade oil | FL/FR |
creamy |
| acetoin butyrate | FL |
| butyl butyryl lactate | FL/FR |
5(6)- | decenoic acid | FL/FR |
2- | methyl-4-pentenoic acid | FL |
dairy |
4- | pentenoic acid | FL |
earthy |
1- | decen-3-ol | FL/FR |
fatty |
| butter acids | FL/FR |
| nonanoic acid | FL/FR |
(E)-2- | octenoic acid | FL |
fermented |
| methyl thio isovalerate | FL |
fruity |
3- | benzyl-4-heptanone | FL/FR |
| cyclohexyl carboxylic acid | FL/FR |
| filbert hexenone | FL/FR |
4- | heptanone | FL/FR |
| methyl 4-methyl valerate | FL/FR |
2- | methyl butyl isovalerate | FL/FR |
2- | methyl butyric acid | FL/FR |
| sorbyl butyrate | FL/FR |
grassy |
| tobacco leaf absolute | FL/FR |
green |
iso | cyclocitral (IFF) | FL/FR |
(E)-2- | hexenal | FL/FR |
para- | methyl hydratropaldehyde | FL/FR |
1- | octen-3-yl acetate | FL/FR |
herbal |
| angelica archangelica seed extract | FL/FR |
| dill seed oil | FL/FR |
| dill seed oil CO2 extract | FL/FR |
| immortelle flower oil | FL/FR |
| lavandin water absolute | FL/FR |
| thyme oil wild or creeping | FL/FR |
meaty |
2- | methyl 3-(methyl thio) furan | FL |
medicinal |
dextro- | camphor | FL/FR |
minty |
| pennyroyal oil | FL/FR |
musk |
| angelica root absolute | FL/FR |
musty |
S-( | methyl thio) butyrate | FL/FR |
nutty |
| nutty quinoxaline | FL/FR |
| pentanoic acid, 3-methyl-2-oxo-, ethyl ester | FL/FR |
oily |
2- | methyl hexanoic acid | FL/FR |
sour |
| butyric acid | FL/FR |
2,4- | dimethyl-2-pentenoic acid | FL |
3- | methyl valeric acid | FL |
spicy |
| cardamom seed oil CO2 extract | FL/FR |
| cinnamon acrolein | FL/FR |
| ginger oleoresin africa | FL/FR |
| ginger root absolute | FL/FR |
| ginger root oil cochin | FL/FR |
2- | octanol | FL/FR |
black | pepper absolute | FL/FR |
black | pepper oil | FL/FR |
white | pepper oil | FL/FR |
black | pepper oleoresin | FL/FR |
para-iso | propyl acetophenone | FL/FR |
sulfurous |
| methyl 4-(methyl thio) butyrate | FL |
sweet |
| cyclohexyl acetic acid | FL/FR |
thujonic |
common | tansy flower oil argentina | FL/FR |
toasted |
| acetyl propionyl | FL/FR |
waxy |
| heptanoic acid | FL/FR |
2- | methyl heptanoic acid | FL/FR |
2- | nonanol | FL/FR |
| undecanoic acid | FL/FR |
woody |
| cadinene | FL/FR |
| patchouli oil | FL/FR |
| patchouli oil CO2 extract | FL/FR |
| patchouli oil decolorized | FL/FR |
| patchouli oil molecular distilled | FL/FR |
alpha- | pinene | FL/FR |
|
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| hexyl methyl ketone | N- | hexyl methyl ketone | | ketone, hexyl methyl | | laventerre | | methyl hexyl cetone | | methyl hexyl ketone | | methyl hexyl ketone 90 | | methyl hexyl ketone, natural | | methyl N-hexyl ketone | | octan-2-one | 2-oxo | octane | | octane-2-one | 2- | octanon | 2- | octanone | 2- | octanone natural |
Articles:
US Patents: | 3,952,024 - Furfurylthioacetone |
PubMed: | Binding of carbonyl flavours to canola, pea and wheat proteins using GC/MS approach. |
US Patents: | 3,931,166 - Certain 2,5-dimethyl-3-thiopyrazines |
PubMed: | Communication: Coordination structure of bromide ions associated with hexyltrimethylammonium cations at liquid/liquid interfaces under potentiostatic control as studied by total-reflection X-ray absorption fine structure. |
PubMed: | Olfactory Sensitivity and Odor Structure-Activity Relationships for Aliphatic Ketones in CD-1 Mice. |
PubMed: | Characterization of aroma compounds of Chinese famous liquors by gas chromatography-mass spectrometry and flash GC electronic-nose. |
PubMed: | Brushed block copolymer micelles with pH-sensitive pendant groups for controlled drug delivery. |
PubMed: | Mass and Ion Transport in Ketones and Ketone Electrolytes: Comparison with Acetate Systems. |
PubMed: | Formation yields of C8 1,4-hydroxycarbonyls from OH + n-octane in the presence of NO. |
PubMed: | Brain phospholipase C, diacylglycerol lipase and monoacylglycerol lipase are involved in (±)-epibatidine-induced activation of central adrenomedullary outflow in rats. |
PubMed: | Analysis of quinolones by voltage-assisted liquid-phase microextraction combined with LC-MS. |
PubMed: | Fragrance material review on methyl hexyl oxo cyclopentanone carboxylate. |
PubMed: | Color, lipid oxidation, sensory quality, and aroma compounds of beef steaks displayed under different levels of oxygen in a modified atmosphere package. |
PubMed: | Electromembrane extraction of peptides--fundamental studies on the supported liquid membrane. |
PubMed: | Evaluation of parallel milliliter-scale stirred-tank bioreactors for the study of biphasic whole-cell biocatalysis with ionic liquids. |
PubMed: | Evaluation of the use of Syzygium cumini fruit extract as an antioxidant additive in orange juice and its sensorial impact. |
PubMed: | Controlling the facial selectivity of asymmetric [4+2] cyclo-additions: a concise synthesis of the cis-decalin core structure of superstolides A and B. |
PubMed: | Thermodynamics and activity coefficients at infinite dilution measurements for organic solutes and water in the ionic liquid N-hexyl-3-methylpyridinium tosylate. |
PubMed: | Comparison of volatile components in Chinese traditional pickled peppers using HS-SPME-GC-MS, GC-O and multivariate analysis. |
PubMed: | Solvent free oxidation of primary alcohols and diols using thymine iron(III) catalyst. |
PubMed: | Novel aspect of ketone action: β-hydroxybutyrate increases brain synthesis of kynurenic acid in vitro. |
PubMed: | Isolation and characterization of 4-tert-butylphenol-utilizing Sphingobium fuliginis strains from Phragmites australis rhizosphere sediment. |
PubMed: | Neurotoxicity of fungal volatile organic compounds in Drosophila melanogaster. |
PubMed: | Prolonged stimulus exposure reveals prolonged neurobehavioral response patterns. |
PubMed: | Hollow fiber-liquid-phase microextraction of fungicides from orange juices. |
PubMed: | Asymmetric [4+2] cycloadditions employing 1,3-dienes derived from (R)-4-t-butyldimethyl-silyloxy-2-cyclohexen-1-one. |
PubMed: | Purification and characterization of an anti-Prelog alcohol dehydrogenase from Oenococcus oeni that reduces 2-octanone to (R)-2-octanol. |
PubMed: | Widespread occurrence of estrogenic UV-filters in aquatic ecosystems in Switzerland. |
PubMed: | Ionic liquid based dispersive liquid-liquid microextraction for the extraction of pesticides from bananas. |
PubMed: | Gas chromatography-olfactometry analysis of the volatile compounds of two commercial Irish beef meats. |
PubMed: | Selective three-phase liquid phase microextraction of acidic compounds from foodstuff simulants. |
PubMed: | Chemical characterization of territorial marking fluid of male Bengal tiger, Panthera tigris. |
PubMed: | Templation of the excited-state chemistry of alpha-(n-alkyl) dibenzyl ketones: how guest packing within a nanoscale supramolecular capsule influences photochemistry. |
PubMed: | Optimization of chlorophyllase-catalyzed hydrolysis of chlorophyll in monophasic organic solvent media. |
PubMed: | Kinetic analysis of volatile formation in milk subjected to pressure-assisted thermal treatments. |
PubMed: | Glial-cytokine-neuronal interactions underlying the mechanisms of persistent pain. |
PubMed: | Purification, characterization, and gene cloning of glycerol dehydrogenase from Hansenula ofunaensis, and its expression for production of optically active diol. |
PubMed: | Anti-prelog reduction of prochiral carbonyl compounds by Oenococcus oeni in a biphasic system. |
PubMed: | Chemical boundaries for detection of eye irritation in humans from homologous vapors. |
PubMed: | Dominant role for calpain in thromboxane-induced neuromicrovascular endothelial cytotoxicity. |
PubMed: | Stability of immobilized soybean lipoxygenase in selected organic solvent media. |
PubMed: | Stereoselective synthesis of c3-c12 dihydropyran portion of antitumor laulimalide using copper-catalyzed oxonium ylide formation-[2,3] shift. |
PubMed: | 1,4-hydroxycarbonyl products of the OH radical initiated reactions of C5-C8 n-alkanes in the presence of NO. |
PubMed: | Bis{1-n-hexyl-3-methyl-4-[1-(phenylimino)propyl]-1H-pyrazol-5-olato}copper(II): a new copper(II) complex with a chelating alkylpyrazolone-based enamine. |
PubMed: | Characterization of French and Spanish dry-cured hams: influence of the volatiles from the muscles and the subcutaneous fat quantified by SPME-GC. |
PubMed: | Designing the "search pathway" in the development of a new class of highly efficient stereoselective hydrosilylation catalysts. |
PubMed: | High-yield conversion of (R)-2-octanol from the corresponding racemate by stereoinversion using Candida rugosa. |
PubMed: | Bimetallic isopropoxides M[Al(OC(3)H(i)(7))(4)](3) (M = Pr, Nd)--catalyzed reduction of 2-octanone and benzophenone. |
PubMed: | Controlled production of Camembert-type cheeses. Part II. Changes in the concentration of the more volatile compounds. |
PubMed: | Use of an ionic liquid in a two-phase system to improve an alcohol dehydrogenase catalysed reduction. |
PubMed: | Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells. |
PubMed: | Volatiles in a sausage surface model-influence of Penicillium nalgiovense, Pediococcus pentosaceus, ascorbate, nitrate and temperature. |
PubMed: | An efficient direct alpha-alkylation of ketones with primary alcohols catalyzed by [Ir(cod)Cl]2/PPh3/KOH system without solvent. |
PubMed: | Analysis of ketones by selected ion flow tube mass spectrometry. |
PubMed: | Synthesis of (4R,6S,7R)-7-hydroxy-4,6-dimethyl-3-nonanone and (3R,5S,6R)- 6-hydroxy-3,5-dimethyl-2-octanone, the pheromone components of the bostrychid beetle, Dinoderus bifoveolatus. |
PubMed: | Associative learning of complex odours in parasitoid host location. |
PubMed: | Relationship between molecular structure, concentration and odor qualities of oxygenated aliphatic molecules. |
PubMed: | Chlorpromazine inhibits the glucocorticoid receptor-mediated gene transcription in a calcium-dependent manner. |
PubMed: | Aroma active components in aqueous kiwi fruit essence and kiwi fruit puree by GC-MS and multidimensional GC/GC-O. |
PubMed: | Influence of lipid fraction, emulsifier fraction, and mean particle diameter of oil-in-water emulsions on the release of 20 aroma compounds. |
PubMed: | Selective Oxidation of Vinyl Ethers and Silyl Enol Ethers with Hydrogen Peroxide Catalyzed by Peroxotungstophosphate. |
PubMed: | An enantiospecific approach to tricyclic sesquiterpenes mayurone and thujopsenes. |
PubMed: | Asymmetric reduction of ketones with catecholborane using 2,6-BODOL complexes of titanium(IV) as catalysts. |
PubMed: | Interactions between artificial saliva and 20 aroma compounds in water and oil model systems. |
PubMed: | Signalling mechanisms underlying the myogenic response in human subcutaneous resistance arteries. |
PubMed: | Efficient oxidation of alcohols to carbonyl compounds with molecular oxygen catalyzed by N-hydroxyphthalimide combined with a Co species |
PubMed: | Interactions between methyl ketones and beta-lactoglobulin: sensory analysis, headspace analysis, and mathematical modeling. |
PubMed: | Blocking and the detection of odor components in blends. |
PubMed: | Interactions of flavor compounds with pectic substances. |
PubMed: | Oxidative cleavage of the octyl side chain of 1-(3,4-dichlorobenzyl)-5-octylbiguanide (OPB-2045) in rat and dog liver preparations. |
PubMed: | Effect of aeration during cell growth on ketone reactions by immobilized yeast. |
PubMed: | Interactions between aroma and edible films. 1. Permeability Of methylcellulose and low-density polyethylene films to methyl ketones. |
PubMed: | Solvent-modified solid-phase microextraction for the determination of diazepam in human plasma samples by capillary gas chromatography. |
PubMed: | An analysis of blocking in odorant mixtures: an increase but not a decrease in intensity of reinforcement produces unblocking. |
PubMed: | Neighboring Group Participation in a Regio- and Stereoselective Chlorination of a Bicyclo[2.2.2]octanone. |
PubMed: | Enhanced sensitivity to androstenone following regular exposure to pemenone. |
PubMed: | Effects of solvation on partition and dimerization of benzoic acid in mixed solvent systems. |
PubMed: | Ketone EC50 values in the Microtox test. |
PubMed: | Structure, stereochemistry, and thermal isomerization of the male sex pheromone of the longhorn beetle Anaglyptus subfasciatus. |
PubMed: | Immiscible organic solvent inactivation of urease, chymotrypsin, lipase, and ribonuclease: separation of dissolved solvent and interfacial effects. |
PubMed: | Juvenile hormone esterase purified by affinity chromatography with 8-mercapto-1,1,1-trifluoro-2-octanone as a rationally designed ligand. |
PubMed: | Sensory irritation and pulmonary irritation of n-methyl ketones: receptor activation mechanisms and relationships with threshold limit values. |
PubMed: | Effect of some metallic cations and organic compounds on the O-hexyl O-2,5-dichlorophenyl phosphoramidate hydrolysing activity in hen plasma. |
PubMed: | Competitive inhibition of lipolytic enzymes. VII. The interaction of pancreatic phospholipase A2 with micellar lipid/water interfaces of competitive inhibitors. |
PubMed: | Electroantennogram response of alfalfa seed chalcid,Bruchophagus roddi (Hymenoptera: Eurytomidae) to host- and nonhost-plant volatiles. |
PubMed: | Antidopaminergic effects of the stereoisomers of N-[(1-alkyl-2- pyrrolidinyl)methyl]-5-sulfamoylbenzamides and -2,3-dihydrobenzofuran-7-carboxamides. |
PubMed: | Inhibition of cathepsin B and papain by peptidyl alpha-keto esters, alpha-keto amides, alpha-diketones, and alpha-keto acids. |
PubMed: | Volatile methyl ketone seed-germination inhibitors fromAmaranthus palmeri S. Wats. Residues. |
PubMed: | Experimental study on the enhancement of the neurotoxicity of methyl n-butyl ketone by non-neurotoxic aliphatic monoketones. |
PubMed: | Neurophysiological studies on the relation between the structural properties and neurotoxicity of aliphatic hydrocarbon compounds in rats. |
PubMed: | Volatile constituents of wolf (Canis lupus) urine as related to gender and season. |
PubMed: | Further studies on ketone neurotoxicity and interactions. |
PubMed: | [An experimental study on the neurotoxicity of 2-octanone and 2-hexanol, a metabolite of n-hexane]. |
PubMed: | Commercial-grade methyl heptyl ketone (5-methyl-2-octanone) neurotoxicity: contribution of 5-nonanone. |
PubMed: | Gas-chromatographic resolution of enantiomeric secondary alcohols. Stereoselective reductive metabolism of ketones in rabbit-liver cytosol. |
PubMed: | Cycloalkanones. 9. Comparison of analogues which inhibit cholesterol and fatty acid synthesis. |
PubMed: | Cycloalkanones. 7. Hypocholesterolemic activity of aliphatic compounds related to 2,8-dibenzylcyclooctanone. |
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