2-acetyl-3-methyl pyrazine
2-acetyl-3-methylpyrazine
 
Notes:
Aroma constit. of spiny lobster (Panulirus argus) roasted sesame seed
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      50024 2-ACETYL-3-METHYL PYRAZINE
       
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      B-026 2-Acetyl-3-methylpyrazine
       
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      2-Acetyl-3-methylpyrazine Halal, Kosher

      Used in soups and sauces at 20ppm, confectionery at 5ppm, meat products at 2ppm, snack foods at 0.25ppm, and desserts at 0.1ppm.
       
       
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Synonyms   Articles   Notes   Search
CAS Number: 23787-80-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 245-889-8
FDA UNII: 7U5TEW2Y2B
Nikkaji Web: J364.475H
MDL: MFCD00014612
CoE Number: 11296
XlogP3-AA: 0.20 (est)
Molecular Weight: 136.15396000
Formula: C7 H8 N2 O
NMR Predictor: Predict (works with chrome, Edge or firefox)
Category: flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Flavoring: 950  2-acetyl-3-methylpyrazine
DG SANTE Food Flavourings: 14.082  2-acetyl-3-methylpyrazine
FEMA Number: 3964 2-acetyl-3-methylpyrazine
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):23787-80-6 ; 2-ACETYL-3-METHYLPYRAZINE
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless to yellow clear liquid (est)
Assay: 98.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 1.11400 to 1.11800 @  25.00 °C.
Pounds per Gallon - (est).: 9.270 to  9.303
Specific Gravity: 1.10500 to 1.11400 @  25.00 °C.
Pounds per Gallon - est.: 9.195 to 9.270
Refractive Index: 1.52000 to 1.52400 @  20.00 °C.
Refractive Index: 1.52100 to 1.52300 @  20.00 °C.
Boiling Point: 265.00 to  266.00 °C. @ 760.00 mm Hg
Boiling Point: 90.00 °C. @ 20.00 mm Hg
Vapor Pressure: 0.105000 mmHg @ 25.00 °C. (est)
Flash Point: 176.00 °F. TCC ( 80.00 °C. )
logP (o/w): -0.484 (est)
Soluble in:
 alcohol
 water, 6.241e+004 mg/L @ 25 °C (est)
Insoluble in:
 water
Stability:
 stable in most media
Similar Items: note
2-acetyl-5-methyl pyrazine
2-acetyl-6-methyl pyrazine
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: nutty
 
Odor Strength: high ,
recommend smelling in a 0.10 % solution or less
 
Substantivity: 25 hour(s) at 100.00 %
 
 nutty  nut flesh  hazelnut roasted hazelnut  grain toasted grain  corn chip  vegetable  nut skin  caramellic  
Odor Description:
at 0.10 % in dipropylene glycol. 
nutty nut flesh roasted hazelnut toasted grain corn chip vegetable nut skin caramellic
Luebke, William tgsc, (2017)
 
 
Flavor Type: nutty
 
 nutty  nut flesh  hazelnut roasted hazelnut  grain toasted grain  potato chip  potato baked potato  nut skin  vegetable  
Taste Description:
nutty nut flesh roasted hazelnut toasted grain potato chip baked potato nut skin vegetable
Luebke, William tgsc, (2017)
 
Odor and/or flavor descriptions from others (if found).
 
R C Treatt & Co Ltd
2-Acetyl-3-methylpyrazine Halal, Kosher
Odor Description: nutty, vegetable, and roasted cereal
Taste Description: nutty
Used in soups and sauces at 20ppm, confectionery at 5ppm, meat products at 2ppm, snack foods at 0.25ppm, and desserts at 0.1ppm.
 
Taytonn ASCC
2-Acetyl-3-methylpyrazine
Odor Description: Roast, Nutty, Caramellic/ Caramel, Toasted, Cereal
 
FCI SAS
2-ACETYL-3-METHYL PYRAZINE
Odor Description: Roast, nutty, vegetable clear sceat, Roast paddy
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
Ambles Nature et Chimie
2-ACETYL-3-METHYL PYRAZINE
Anhui Haibei
2-Acetyl-3-methyl Pyrazine
Odor: Roasted nutty vegetable toasted grain
Anhui Suzhou Jinli Aromatic Chemicals
2-Acetyl-3-methyl Pyrazine
Odor: roast, nut, vegetable, Baked corn
Augustus Oils
2 Acetyl 3 Methyl Pyrazine
Services
Beijing Lys Chemicals
2-Acetyl-3-methylpyrazine
BOC Sciences
For experimental / research use only.
2-Acetyl-3-methylpyrazine
Carbosynth
For experimental / research use only.
2-Acetyl-3-methylpyrazine
Charkit Chemical
ACETYL-3-METHYLPYRAZINE, 2- FEMA 3964
Diffusions Aromatiques
2-ACETYL-3-METHYLPYRAZINE
Ernesto Ventós
2-ACETYL-3-METHYLPYRAZINE
Odor: NUTTY, ROASTED, VEGETABLE
FCI SAS
2-ACETYL-3-METHYL PYRAZINE
Odor: Roast, nutty, vegetable clear sceat, Roast paddy
Frutarom
2-ACETYL-3-METHYLPYRAZINE
KOSHER
Flavor: Nutty, Flesh, Roasted, Grain
CBD Offering
IFF
2-ACETYL-3-METHYLPYRAZINE
KOSHER
Flavor: Nutty, Flesh, Roasted, Grain
Jiangyin Healthway
2-Acetyl-3-methyl Pyrazine
New functional food ingredients
Jinan Enlighten Chemical Technology(Wutong Aroma )
2-Acetyl-3-methyl pyrazine, Kosherk
Kingchem Laboratories
2 ACETYL-3-METHYLPYRAZINE
Odor: Roast, nutty, vegetable clear scent
Lluch Essence
PYRAZINE 2-ACETHYL-3-METHYL
M&U International
2-ACETYL-3-METHYL PYRAZINE, Kosher
Matrix Scientific
For experimental / research use only.
2-Acetyl-3-methylpyrazine, 98%
Pearlchem Corporation
2-Acetyl-3-methyl Pyrazine
Penta International
2-ACETYL-3-METHYL PYRAZINE
R C Treatt & Co Ltd
2-Acetyl-3-methylpyrazine
Halal, Kosher
Odor: nutty, vegetable, and roasted cereal
Flavor: nutty
Used in soups and sauces at 20ppm, confectionery at 5ppm, meat products at 2ppm, snack foods at 0.25ppm, and desserts at 0.1ppm.
Reincke & Fichtner
2-Acetyl-3-methyl Pyrazine
Sigma-Aldrich
2-Acetyl-3-methylpyrazine, ≥98%, FG
Certified Food Grade Products
Sunaux International
2-Acetyl-3-methyl Pyrazine
Synerzine
2-Acetyl-3-Methylpyrazine
Taytonn ASCC
2-Acetyl-3-methylpyrazine
Odor: Roast, Nutty, Caramellic/ Caramel, Toasted, Cereal
TCI AMERICA
For experimental / research use only.
2-Acetyl-3-methylpyrazine >98.0%(GC)
Tengzhou Jitian Aroma Chemiclal
2-Acetyl-3-methyl Pyrazine
Tengzhou Xiang Yuan Aroma Chemicals
2-Acetyl-3-methyl Pyrazine
Tianjin Danjun International
2-Acetyl-3-methylpyrazine
United International
2-Acetyl-3-Methyl Pyrazine
WholeChem
2-Acetyl-3-methyl pyrazine
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavoring agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for 2-acetyl-3-methyl pyrazine usage levels up to:
  0.1000 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.10 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.10 (μg/capita/day)
Structure Class: II
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 20
Click here to view publication 20
 average usual ppmaverage maximum ppm
baked goods: 1.300004.30000
beverages(nonalcoholic): 0.300000.60000
beverages(alcoholic): 0.300003.00000
breakfast cereal: 0.100002.00000
cheese: --
chewing gum: 0.800008.00000
condiments / relishes: --
confectionery froastings: 0.300003.00000
egg products: 0.300003.00000
fats / oils: 0.300003.00000
fish products: 0.100003.00000
frozen dairy: 1.000005.00000
fruit ices: 0.200002.00000
gelatins / puddings: 0.200002.00000
granulated sugar: --
gravies: 0.300003.00000
hard candy: 0.500005.00000
imitation dairy: --
instant coffee / tea: 0.100001.00000
jams / jellies: 0.500005.00000
meat products: 1.300005.00000
milk products: 0.300003.00000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: 0.500005.00000
snack foods: 0.500005.00000
soft candy: 1.000004.00000
soups: 1.000002.50000
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s):
The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. View pdf
European Food Safety Athority(EFSA): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf
Flavouring Group Evaluation 50 (FGE.50): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) [1]
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 50, Revision 1 (FGE.50Rev1): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17Rev2 (2010)
View page or View pdf
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 23787-80-6
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 32093
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 1-(3-methylpyrazin-2-yl)ethanone
Chemidplus: 0023787806
Synonyms   Articles   Notes   Search   Top
References:
 1-(3-methylpyrazin-2-yl)ethanone
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 23787-80-6
Pubchem (cid): 32093
Pubchem (sid): 134994225
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
HMDB (The Human Metabolome Database): HMDB30001
FooDB: FDB001290
Export Tariff Code: 2933.99.8290
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
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Potential Blenders and core components note
 
For Odor
No odor group found for these
 sulfuryl octanoateFL/FR
 sulfuryl butyrateFL/FR
 sulfuryl decanoateFL/FR
 sulfuryl hexanoateFL/FR
 sulfuryl isobutyrateFL/FR
 sulfuryl propionateFL/FR
caramellic
isopropenyl pyrazineFL/FR
chocolate
2,5-dimethyl pyrazineFL/FR
2,4,5-trimethyl thiazoleFL/FR
floral
ortho-methyl acetophenoneFL/FR
alloocimeneFL/FR
fruity
 tropical thiazoleFL/FR
green
2-heptyl furanFL/FR
2-acetyl-3,5-dimethyl pyrazineFL/FR
2-acetyl-3,5(or 6)-dimethyl pyrazineFL/FR
5-acetyl-4-methyl thiazole 
roasted chestnut fragranceFR
3,6-cocoa pyrazineFL/FR
2,4-dimethyl-5-ethyl thiazole 
 filbert heptenoneFL/FR
 filbert heptenone BFL/FR
 methoxymethyl pyrazineFL/FR
 nutty quinoxalineFL/FR
 sesame absoluteFL/FR
roasted
2-acetyl-2-pyrroline 
sulfurous
 furfuryl thioacetateFL/FR
 
For Flavor
 
No flavor group found for these
2-acetyl-2-pyrroline 
5-acetyl-4-methyl thiazole 
6,7-dihydro-2,3-dimethyl-5H-cyclopentapyrazineFL
 dimethyl dihydrocyclopentapyrazineFL
6,7-dimethyl dihydrocyclopentapyrazineFL
2,5-dimethyl pyrazine and 2,6-dimethyl pyrazine mixtureFL
2,5-dimethyl thiazoleFL
2,4-dimethyl-5-ethyl thiazole 
 methyl 2-(methyl thio) acetateFL
 pyrazines mixtureFL
 sulfuryl butyrateFL/FR
 sulfuryl decanoateFL/FR
 sulfuryl hexanoateFL/FR
 sulfuryl isobutyrateFL/FR
5-acetyl-2,3-dihydro-1,4-thiazineFL
 sulfuryl formateFL
 sulfuryl octanoateFL/FR
 sulfuryl propionateFL/FR
alliaceous
 tropical thiazoleFL/FR
anisic
ortho-methyl acetophenoneFL/FR
burnt
isopropenyl pyrazineFL/FR
citrus
alloocimeneFL/FR
fatty
2-heptyl furanFL/FR
fishy
4,5-dimethyl thiazoleFL
fruity
2-ethyl-2,5-dihydro-4-methyl thiazoleFL
2,4-hexadien-1-olFL
green
2-hexyl pyridineFL
4-methyl thiazoleFL
2-propyl pyrazineFL
milky
dextro,laevo-3-(methyl thio) butanoneFL
musty
2,5-dimethyl pyrazineFL/FR
2-ethoxythiazoleFL
nutty
3-acetyl-2,5-dimethyl thiopheneFL
2-acetyl-3,5-dimethyl pyrazineFL/FR
2-acetyl-3,5(or 6)-dimethyl pyrazineFL/FR
 aconitic acidFL
 arachis hypogaea fruit extractFL
3,6-cocoa pyrazineFL/FR
1-ethyl-2-acetyl pyrroleFL
 filbert heptenoneFL/FR
 filbert heptenone BFL/FR
 methoxymethyl pyrazineFL/FR
 nutty quinoxalineFL/FR
 peanut oxazoleFL
 sesame absoluteFL/FR
2,4,5-trimethyl thiazoleFL/FR
popcorn
2-propionyl-2-thiazolineFL
roasted
3,5-diisobutyl-1,2,4-trithiolaneFL
 furfuryl thioacetateFL/FR
 
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Potential Uses:
 caramelFL
 cerealFL
 chocolate cocoaFL
 coffeeFR
 filbertFR
 grainFL
 hazelnutFR
 meatFL
 nut roasted nutFL
 peanutFR
 popcornFR
 sesameFL
 shellfishFL
 walnutFL
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Occurrence (nature, food, other): note
 clam
Search  PMC Picture
 cocoa
Search Trop  Picture
 coffee
Search  PMC Picture
 meat
Search  PMC Picture
 pork fried pork
Search  PMC Picture
 potato french fries
Search  PMC Picture
 scallop
Search  PMC Picture
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Synonyms:
2-acetyl-3-methylpyrazine
2 acetyl-3-methylpyrazine
2-acetyl-3-methylpyrazine >98.0%(GC)
2-acetyl-3-methylpyrazine 98%
 ethanone, 1-(3-methyl-2-pyrazinyl)-
1-ethanone, 1-(3-methyl-2-pyrazinyl)-
 ethanone, 1-(3-methylpyrazinyl)-
1-(3-methyl pyrazinyl) ethan-1-one
1-(3-methyl pyrazinyl) ethanone
2-methyl-3-acetyl pyrazine
2-methyl-3-acetylpyrazine
1-(3-methylpyrazin-2-yl)ethan-1-one
1-(3-methylpyrazin-2-yl)ethanone
1-(3-methylpyrazinyl)ethan-1-one
 pyrazine, 2-acetyl-3-methyl-
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Articles:
PubMed: Evaluation of process parameters governing the aroma generation in three hazelnut cultivars (Corylus avellana L.) by correlating quantitative key odorant profiling with sensory evaluation.
PubMed: Characterization of the key odorants in pan-fried white mushrooms (Agaricus bisporus L.) by means of molecular sensory science: comparison with the raw mushroom tissue.
PubMed: Characterization of the aroma signature of styrian pumpkin seed oil ( Cucurbita pepo subsp. pepo var. Styriaca) by molecular sensory science.
PubMed: 2-Acetyl-3-methyl-pyrazine phenyl-sulfonyl-hydrazone.
PubMed: Bis[2-acetyl-3-methyl-pyrazine (2-hydroxy-benzo-yl)hydrazonato]zinc(II) monohydrate.
PubMed: Identification of potent odorants in different green tea varieties using flavor dilution technique.
PubMed: Studies on the key odorants formed by roasting of wild mango seeds (Irvingia gabonensis).
PubMed: Volatile flavor components of rice cakes.
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