Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | pale yellow to yellow clear liquid (est) |
Assay: | 98.00 to 100.00 %
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Food Chemicals Codex Listed: | No |
Specific Gravity: | 1.07700 to 1.08100 @ 25.00 °C.
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Pounds per Gallon - (est).: | 8.962 to 8.995
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Specific Gravity: | 1.06800 to 1.07900 @ 25.00 °C.
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Pounds per Gallon - est.: | 8.887 to 8.978
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Refractive Index: | 1.51200 to 1.51600 @ 20.00 °C.
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Boiling Point: | 220.00 to 221.00 °C. @ 760.00 mm Hg
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Boiling Point: | 54.00 to 56.00 °C. @ 1.00 mm Hg
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Vapor Pressure: | 0.026000 mmHg @ 25.00 °C. (est) |
Flash Point: | > 212.00 °F. TCC ( > 100.00 °C. )
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logP (o/w): | 0.026 (est) |
Soluble in: |
| alcohol | | water | | water, 2.072e+004 mg/L @ 25 °C (est) |
Similar Items: note |
2-acetyl-6-ethyl pyrazine |
Organoleptic Properties:
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Odor Type: nutty |
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| earthy potato chip nutty popcorn corn |
Odor Description: at 1.00 % in propylene glycol. | earthy potato chip nutty popcorn corn |
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| earthy nutty musty potato corn |
Odor Description: at 2.00 %. | Earthy, nutty, musty, potato and corn-like Mosciano, Gerard P&F 23, No. 3, 55, (1998) |
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Flavor Type: nutty |
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| musty nutty cocoa peanut vegetable potato beany |
Taste Description: at 2.00 ppm. | Musty, nutty, cocoa and peanut, with a vegetative, potato and bean nuance Mosciano, Gerard P&F 23, No. 3, 55, (1998) |
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Odor and/or flavor descriptions from others (if found). |
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R C Treatt & Co Ltd |
2-Acetyl-3-ethylpyrazine Halal, Kosher |
Odor Description: | Potato chip, nutty, popcorn, hazelnut, meaty notes |
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Pell Wall Perfumes |
Chip Pyrazine |
Odor Description: | Earthy, nutty, musty, potato-chip, corn Naturally present in cocoa, chocolate as well as cooked meats, this is a more versatile material than you might expect, and an ideal component of the dank, earthy accords that have become popular recently in the more adventurous fine fragrances. |
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Cosmetic Information:
Suppliers:
Ambles Nature et Chimie |
2-ACETYL-3-ETHYL PYRAZINE
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Anhui Haibei |
2-Acetyl-3-ethyl Pyrazine
Odor: Earthy potato chip nutty popcorn corn |
Beijing Lys Chemicals |
2-Acetyl-3-ethylpyrazine
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BOC Sciences |
For experimental / research use only. |
2-Acetyl-3-ethylpyrazine
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Endeavour Specialty Chemicals |
2-Acetyl-3-ethylpyrazine 99% F&F
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Speciality Chemical Product Groups |
Ernesto Ventós |
2-ACETYL-3-ETHYLPYRAZINE
Odor: EARTHY, NUTTY, POTATO, ROAST |
FCI SAS |
2-ACETYL-3-ETHYLPYRAZINE
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Frutarom |
2-ACETYL-3-ETHYLPYRAZINE
KOSHER Flavor: Earthy, Nutty, Corn, Musty |
CBD Offering |
IFF |
2-ACETYL-3-ETHYLPYRAZINE
KOSHER Flavor: Earthy, Nutty, Corn, Musty |
Jinan Enlighten Chemical Technology(Wutong Aroma ) |
2-Acetyl-3-ethyl pyrazine, Kosherk
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Kingchem Laboratories |
2 ACETYL-3-ETHYLPYRAZINE
Odor: Nutty |
Lluch Essence |
PYRAZINE 2-ACETHYL-3-ETHYL
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M&U International |
2-ACETYL-3-ETHYL PYRAZINE, Kosher
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Pearlchem Corporation |
2-Acetyl-3-ethyl Pyrazine
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Pell Wall Perfumes |
Chip Pyrazine
Odor: Earthy, nutty, musty, potato-chip, corn Use: Naturally present in cocoa, chocolate as well as cooked meats, this is a more versatile material than you might expect, and an ideal component of the dank, earthy accords that have become popular recently in the more adventurous fine fragrances. |
Penta International |
2-ACETYL-3-ETHYL PYRAZINE
|
R C Treatt & Co Ltd |
2-Acetyl-3-ethylpyrazine
Halal, Kosher Odor: Potato chip, nutty, popcorn, hazelnut, meaty notes |
Reincke & Fichtner |
2-Acetyl-3-ethylpyrazine
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Robinson Brothers |
2-Acetyl-3-ethylpyrazine F&F
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https://www.robinsonbrothers.uk/chemistry-competences |
Santa Cruz Biotechnology |
For experimental / research use only. |
2-Acetyl-3-ethylpyrazine
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Sigma-Aldrich |
2-Acetyl-3-ethylpyrazine, 98%, FG
Odor: oily; meaty; nutty; vegetable |
Certified Food Grade Products |
Sunaux International |
2-Acetyl-3-ethyl Pyrazine
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Synerzine |
2-Acetyl-3-Ethylpyrazine
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Taytonn ASCC |
2-Acetyl-3-ethylpyrazine
Odor: Earthy, Nutty, Potatoes, Roast |
TCI AMERICA |
For experimental / research use only. |
2-Acetyl-3-ethylpyrazine >98.0%(GC)
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Tengzhou Jitian Aroma Chemiclal |
2-Acetyl-3-ethyl Pyrazine
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Tengzhou Xiang Yuan Aroma Chemicals |
2-Acetyl-3-ethyl Pyrazine
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United International |
2-Acetyl-3-Ethyl pyrazine
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WholeChem |
2-Acetyl-3-ethylpyrazine
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Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xi - Irritant |
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
Recommendation for 2-acetyl-3-ethyl pyrazine usage levels up to: | | 0.2000 % in the fragrance concentrate.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.73 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.10 (μg/capita/day) |
Structure Class: | II |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 5 |
Click here to view publication 5 |
| average usual ppm | average maximum ppm |
baked goods: | - | 10.00000 |
beverages(nonalcoholic): | - | 10.00000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | 10.00000 |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 10.00000 |
fruit ices: | - | 10.00000 |
gelatins / puddings: | - | 10.00000 |
granulated sugar: | - | - |
gravies: | - | 10.00000 |
hard candy: | - | 10.00000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | 10.00000 |
meat products: | - | 10.00000 |
milk products: | - | 10.00000 |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | 10.00000 |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s): |
The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. View pdf |
European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf |
Flavouring Group Evaluation 50 (FGE.50): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) [1] View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 50, Revision 1 (FGE.50Rev1): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17Rev2 (2010) View page or View pdf |
Safety and efficacy of pyrazine derivatives including saturated ones belonging to chemical group 24 when used as flavourings for all animal species View page or View pdf |
EPI System: | View |
AIDS Citations: | Search |
Cancer Citations: | Search |
Toxicology Citations: | Search |
EPA Substance Registry Services (TSCA): | 32974-92-8 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 61918 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 3 |
| 1-(3-ethylpyrazin-2-yl)ethanone |
Chemidplus: | 0032974928 |
References:
Other Information:
Potential Blenders and core components note
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For Odor |
balsamic |
balsamic |
| amyl phenyl acetate | FL/FR |
| butyl cinnamate | FL/FR |
| prenyl benzoate | FL/FR |
caramellic |
| geranyl crotonate | FR |
chocolate |
iso | amyl phenyl acetate | FL/FR |
iso | butyl phenyl acetate | FL/FR |
| chocolate pyrazine A | FL/FR |
| cocoa hexenal | FL/FR |
| cocoa oleoresin | FL/FR |
2,5- | dimethyl pyrazine | FL/FR |
2,4,5- | trimethyl thiazole | FL/FR |
| popcorn pyrimidine | FL/FR |
earthy |
2- | ethyl-3-methoxypyrazine | FL/FR |
| nutty pyrazine | FL/FR |
floral |
alpha- | amyl cinnamyl acetate | FL/FR |
| amyl salicylate | FL/FR |
| autumn carboxylate | FR |
green |
2-sec- | butyl-3-methoxypyrazine | FL/FR |
| geranium thiazole | FL/FR |
herbal |
| acorn acetate | FR |
| tricyclodecenyl isobutyrate | FR |
honey |
| butyl phenyl acetate | FL/FR |
| phenyl acetic acid | FL/FR |
medicinal |
| quinoline | CS |
musty |
2- | acetyl pyrrole | FL/FR |
3- | acetyl-2,5-dimethyl furan | FL/FR |
| cocoa butenal | FL/FR |
| hazelnut pyrazine | FL/FR |
| menthofuran | FL/FR |
nutty |
3- | acetyl pyridine | FL/FR |
2- | acetyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
2- | acetyl-5-methyl furan | FL/FR |
3,6- | cocoa pyrazine | FL/FR |
4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
2- | ethyl pyrazine | FL/FR |
| filbert pyrazine | FL/FR |
2- | methyl pyrazine | FL/FR |
5- | methyl quinoxaline | FL/FR |
2- | methyl thio-3,5 or 6-methyl pyrazine | FL/FR |
| nutty cyclohexenone | FL/FR |
| nutty quinoxaline | FL/FR |
2,3,5,6- | tetramethyl pyrazine | FL/FR |
2,3,5- | trimethyl pyrazine | FL/FR |
| vinyl sulfurol | FL/FR |
popcorn |
2- | acetyl pyrazine | FL/FR |
2- | acetyl pyridine | FL/FR |
2- | acetyl thiazole | FL/FR |
sulfurous |
| dimethyl sulfide | FL/FR |
truffle |
2- | methyl acetoin | |
vanilla |
| ethyl vanillin isobutyrate | FL/FR |
| vanillin | FL/FR |
| vanillyl isobutyrate | FL/FR |
vegetable |
| mesityl oxide | FL/FR |
| methional | FL/FR |
waxy |
2- | tridecanone | FL/FR |
woody |
4- | hydroxybenzaldehyde | FL/FR |
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For Flavor |
|
No flavor group found for these |
2- | acetyl-5-methyl pyrazine | FL |
2- | acetyl-6-methyl pyrazine | FL |
| amyl phenyl acetate | FL/FR |
| butyl cinnamate | FL/FR |
| chocolate pyrazine A | FL/FR |
| chocolate pyrazine B | FL |
| dimethyl dihydrocyclopentapyrazine | FL |
6,7- | dimethyl dihydrocyclopentapyrazine | FL |
| ethyl dimethyl pyrazine | FL |
2- | ethyl-3-methoxypyrazine | FL/FR |
| green pea pyrazine | FL |
2- | methoxy-3-propyl pyrazine | FL |
| methyl 2-(methyl thio) acetate | FL |
2- | methyl acetoin | |
4-( | methyl thio) butanol | FL |
| prenyl benzoate | FL/FR |
2- | propionyl pyrrole | FL |
alliaceous |
3- | mercapto-2-pentanone | FL |
2- | methyl thioacetaldehyde | FL |
ammoniacal |
2- | methyl piperidine | FL |
aromatic |
| amyl salicylate | FL/FR |
bitter |
| methyl ethoxypyrazine | FL |
| paullinia cupana seed extract | FL |
bready |
2- | propionyl thiazole | FL |
chocolate |
| cocoa oleoresin | FL/FR |
| cocoa propanal | FL |
cocoa |
iso | butyl phenyl acetate | FL/FR |
| butyraldehyde | FL |
| cocoa hexenal | FL/FR |
2- | methyl furan | FL |
coffee |
| difurfuryl ether | FL |
corn |
2- | acetyl pyridine | FL/FR |
2- | acetyl thiazole | FL/FR |
2- | acetyl-2-thiazoline | FL |
| popcorn pyrimidine | FL/FR |
creamy |
4- | hydroxybenzaldehyde | FL/FR |
earthy |
alpha- | amyl cinnamyl acetate | FL/FR |
fatty |
2- | tridecanone | FL/FR |
floral |
iso | amyl phenyl acetate | FL/FR |
| phenyl acetic acid | FL/FR |
green |
| cocoa butenal | FL/FR |
| dihydroxyacetophenone (mixed isomers) | FL |
| geranium thiazole | FL/FR |
2- | methyl-5-isopropyl pyrazine | FL |
| propylene glycol acetone ketal | FL |
honey |
| butyl phenyl acetate | FL/FR |
malty |
| yeast thiazoline | FL |
milky |
dextro,laevo-3-( | methyl thio) butanone | FL |
musty |
2,5- | dimethyl pyrazine | FL/FR |
| hazelnut pyrazine | FL/FR |
| menthofuran | FL/FR |
| propionaldehyde | FL |
2,3,5- | trimethyl pyrazine | FL/FR |
nutty |
3- | acetyl pyridine | FL/FR |
2- | acetyl pyrrole | FL/FR |
3- | acetyl-2,5-dimethyl furan | FL/FR |
2- | acetyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
2- | acetyl-5-methyl furan | FL/FR |
3,6- | cocoa pyrazine | FL/FR |
4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
2- | ethyl pyrazine | FL/FR |
2- | ethyl-6-methyl pyrazine | FL |
| filbert pyrazine | FL/FR |
2- | methyl pyrazine | FL/FR |
5- | methyl quinoxaline | FL/FR |
2- | methyl thio-3,5 or 6-methyl pyrazine | FL/FR |
| nutty cyclohexenone | FL/FR |
| nutty pyrazine | FL/FR |
| nutty quinoxaline | FL/FR |
| nutty thiazole | FL |
| peanut oxazole | FL |
2,3,5,6- | tetramethyl pyrazine | FL/FR |
2,4,5- | trimethyl thiazole | FL/FR |
| vinyl sulfurol | FL/FR |
potato |
| mesityl oxide | FL/FR |
roasted |
2- | acetyl pyrazine | FL/FR |
sulfurous |
| dimethyl sulfide | FL/FR |
| potato butanone | FL |
tomato |
| methional | FL/FR |
vanilla |
| ethyl vanillin isobutyrate | FL/FR |
| vanillin | FL/FR |
| vanillyl isobutyrate | FL/FR |
vegetable |
2-sec- | butyl-3-methoxypyrazine | FL/FR |
| potato butyraldehyde | FL |
winey |
5- | ethyl-2-methyl pyridine | FL |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
2- | acetyl-3-ethyl-1,4-diazine | 2- | acetyl-3-ethylpyrazine | 2 | acetyl-3-ethylpyrazine | 2- | acetyl-3-ethylpyrazine 99% | | chip pyrazine | | ethanone, 1-(3-ethyl-2-pyrazinyl)- | | ethanone, 1-(3-ethylpyrazinyl)- | 1-(3- | ethyl pyrazinyl)ethan-1-one | 3- | ethyl-2-pyrazinyl methyl ketone | 3- | ethyl-2-pyrazinylmethyl ketone | 1-(3- | ethylpyrazin-2-yl)ethanone | 1-(3- | ethylpyrazinyl)ethan-1-one |
Articles:
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