Category: fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | off-white crystals or solid (est) |
Assay: | 97.00 to 100.00 % sum of isomers
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Food Chemicals Codex Listed: | No |
Melting Point: | 37.00 to 58.00 °C. @ 760.00 mm Hg
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Boiling Point: | 393.00 °C. @ 760.00 mm Hg
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Vapor Pressure: | 0.000111 mmHg @ 25.00 °C. (est) |
Flash Point: | > 212.00 °F. TCC ( > 100.00 °C. )
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logP (o/w): | 4.536 (est) |
Soluble in: |
| alcohol | | diethyl phthalate | | most solvents | | paraffin oil | | water, 0.2545 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Stability: |
| acids | | alcohol, good | | alkalis | | bar soap, good | | cream rinse, excellent | | deo pump spray, good | | fabric softener, good | | hand cream, good | | liquid detergent, good | | non-discoloring in most media | | oxidizing agents | | reducing agents |
Organoleptic Properties:
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Odor Type: musk |
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Odor Strength: | medium , recommend smelling in a 10.00 % solution or less |
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Substantivity: | 384 hour(s) at 10.00 % in dipropylene glycol |
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| sweet musk amber powdery dry fruity |
Odor Description: at 10.00 % in dipropylene glycol. | strong sweet musk amber powdery dry fruity Luebke, William tgsc, (1985) |
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Odor and/or flavor descriptions from others (if found). |
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PerfumersWorld |
Fixolide |
Odor Description: | strong sweet fruity musk powdery |
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Indukern F&F |
PHANTOLID |
Odor Description: | MUSK, SWEET, CLEAN |
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Pell Wall Perfumes |
Tonalid |
Odor Description: | Musk, sweet, amber, clean, powdery, dry, fruit. Strong Crystals of this widely used, clean, diffusive musk: one of the few early non-Nitro-musks that has stood the test of time and continues to be used extensively in modern perfumery. According to Scent and Chemistry, “Tonalide/Fixolide gives a very special accord with coumarin that is much desirable in constructing male fougere perfumes.” |
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Cosmetic Information:
Suppliers:
BOC Sciences |
For experimental / research use only. |
5-Acetyl-1,1,2,3,3,6-hexamethylindane
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Ernesto Ventós |
PHANTOLID CRYSTALS PFW
Odor: CLEAN AND SWEET MUSK |
Indukern F&F |
PHANTOLID
Odor: MUSK, SWEET, CLEAN |
Keva |
PHANTOLID CRYSTALS
Odor: has a clean sweet musk odour |
Lluch Essence |
PHANTOLID CRYSTALS ® PFW
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Moellhausen |
PHANTOLID
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PCW France |
Phantolid® crystals
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Steps to a fragranced product |
Pell Wall Perfumes |
Tonalid
Odor: Musk, sweet, amber, clean, powdery, dry, fruit. Strong Use: Crystals of this widely used, clean, diffusive musk: one of the few early non-Nitro-musks that has stood the test of time and continues to be used extensively in modern perfumery. According to Scent and Chemistry, “Tonalide/Fixolide gives a very special accord with coumarin that is much desirable in constructing male fougere perfumes.” |
Penta International |
FIXOLIDE
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Penta International |
PHANTOLIDE
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PerfumersWorld |
Fixolide 10% in DPG
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PerfumersWorld |
Fixolide
Odor: strong sweet fruity musk powdery |
Santa Cruz Biotechnology |
For experimental / research use only. |
Phantolide
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SRS Aromatics |
PHANTOLID
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The John D. Walsh Company |
Phantolid Crystals
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Zanos |
Ganolid
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Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xi - Irritant |
R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | fragrance agents |
RIFM Fragrance Material Safety Assessment: Search |
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
IFRA Critical Effect: | Phototoxicity |
IFRA fragrance material specification: | | The Standard is set due to the phototoxic effects of the material. The limit only applies to applications on skin, excluding rinse-off products.
If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic ingredients, expressed in % of their recommended maximum level in the consumer product shall not exceed 100. |
IFRA: | View Standard |
View IFRA Standards Library for complete information. |
Please review Amendment 49 IFRA documentation for complete information. |
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%): |
Category 1: Products applied to the lips |
2.00 % |
Category 2: Products applied to the axillae |
2.00 % |
Category 3: Products applied to the face/body using fingertips |
2.00 % |
Category 4: Products related to fine fragrance |
2.00 % |
| Category 5: Products applied to the face and body using the hands (palms), primarily leave-on |
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on |
2.00 % |
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on |
2.00 % |
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on |
2.00 % |
Category 5D: Baby Creams, baby Oils and baby talc |
2.00 % |
Category 6: Products with oral and lip exposure |
2.00 % |
| Category 7: Products applied to the hair with some hand contact |
Category 7A: Rinse-off products applied to the hair with some hand contact |
No Restriction % |
Category 7B: Leave-on products applied to the hair with some hand contact |
2.00 % |
Category 8: Products with significant anogenital exposure |
2.00 % |
Category 9: Products with body and hand exposure, primarily rinse off |
No Restriction % |
| Category 10: Household care products with mostly hand contact |
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products) |
No Restriction % |
Category 10B: Household aerosol/spray products |
2.00 % |
| Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate |
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure |
No Restriction % |
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure |
2.00 % |
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin |
No Restriction |
| Notes: |
IFRA FLAVOR REQUIREMENTS: |
Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards. |
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Recommendation for musk indane flavor usage levels up to: |
| not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
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For Odor |
No odor group found for these |
| amber romance fragrance | FR |
(Z)-iso | ambrettolide | FR |
aldehydic |
| dodecanal (aldehyde C-12 lauric) | FL/FR |
amber |
| amber oxepin | FR |
| amber powdery floral fragrance | FR |
| amber spirolene | FR |
| ambergris specialty | FR |
| ambrette seed absolute | FL/FR |
| ambrette seed oil | FL/FR |
| ambrette seed oil CO2 extract | FL/FR |
| ambrette seed oil replacer | FR |
| ambroxan | FL/FR |
| angelica root oil | FL/FR |
| cistus ladaniferus resinoid | FL/FR |
(cis+trans)-6,6a,7,8,9,9a- | hexahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline | FR |
| muscomer | FR |
animal |
| animal carbolactone | FR |
| costus valerolactone | FR |
para- | cresyl phenyl acetate | FL/FR |
| indole | FL/FR |
2- | methyl-4-(camphenyl-8) cyclohexanone | FR |
balsamic |
iso | amyl benzoate | FL/FR |
| amyris wood oil | FL/FR |
siam | benzoin resinoid | FL/FR |
| benzyl salicylate | FL/FR |
iso | butyl cinnamate | FL/FR |
| cinnamyl alcohol | FL/FR |
| clover nitrile | FR |
| ethyl cinnamate | FL/FR |
| fir balsam absolute | FR |
| methyl (E)-cinnamate | FL/FR |
| myrrh oil | FL/FR |
3- | phenyl propyl alcohol | FL/FR |
berry |
| raspberry ketone | FL/FR |
| raspberry ketone acetate | FL/FR |
| raspberry ketone methyl ether | FL/FR |
caramellic |
| ethyl maltol | FL/FR |
coconut |
gamma- | heptalactone | FL/FR |
gamma- | octalactone | FL/FR |
fatty |
| decanol | FL/FR |
floral |
alpha- | amyl cinnamaldehyde | FL/FR |
iso | amyl salicylate | FL/FR |
| bois de rose oil brazil | FL/FR |
| citronellol | FL/FR |
| coriander seed oil | FL/FR |
| cyclamen aldehyde | FL/FR |
9- | decen-1-ol | FL/FR |
| dimethyl benzyl carbinol | FL/FR |
| floral pyranol | FR |
| heliotropin | FL/FR |
| heliotropyl acetone | FL/FR |
| heliotropyl diethyl acetal | FR |
(Z)-3- | hexen-1-yl salicylate | FL/FR |
alpha- | hexyl cinnamaldehyde | FL/FR |
| ho leaf oil | FR |
| hyacinth ether | FR |
| hydroxycitronellal | FL/FR |
laevo- | linalool | FL/FR |
| linalool oxide | FL/FR |
para- | methyl acetophenone | FL/FR |
| methyl dihydrojasmonate | FL/FR |
alpha-iso | methyl ionone (50% min.) | FL/FR |
alpha-iso | methyl ionone (90% min.) | FL/FR |
| muguet carboxaldehyde | FR |
| muguet octadienol | FR |
| nerolidol | FL/FR |
| ocean propanal | FL/FR |
| orris pyridine 25% IPM | FR |
| papaya isobutyrate | FL/FR |
| phenethyl alcohol | FL/FR |
| phenethyl phenyl acetate | FL/FR |
| rhodinol | FL/FR |
fruity |
| acetyl methyl anthranilate | FL/FR |
| allyl amyl glycolate | FR |
gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
| valeriana officinalis root extract | FL/FR |
hay |
| hay absolute | FR |
herbal |
| clary sage oil france | FL/FR |
| daucus carota fruit oil | FL/FR |
marine |
| marine pyridine | FR |
melon |
| watermelon ketone | FR |
mossy |
| oakmoss absolute | FL/FR |
| veramoss (IFF) | FR |
musk |
| musk lactone | FR |
| musk methyl ketone | FR |
| musk tetralin | FL/FR |
6,7,8,9- | tetrahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline | FR |
naphthyl |
beta- | naphthyl ethyl ether | FL/FR |
powdery |
para- | anisyl alcohol | FL/FR |
alpha- | methyl ionone | FL/FR |
(E)-alpha- | methyl ionone (74-80%) | FL/FR |
| midnight passion fragrance | FR |
spicy |
para- | anisyl formate | FL/FR |
| cassia bark oil china | FL/FR |
iso | eugenyl acetate | FL/FR |
alpha- | methyl cinnamaldehyde | FL/FR |
| methyl isoeugenol | FL/FR |
black | pepper oil | FL/FR |
terpenic |
| frankincense oil | FL/FR |
tonka |
| coumarin | FR |
gamma- | hexalactone | FL/FR |
| tonka bean absolute | FR |
vanilla |
| ethyl vanillin | FL/FR |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
| vanillyl acetate | FL/FR |
waxy |
| decyl acetate | FL/FR |
1- | dodecanol | FL/FR |
| ethyl laurate | FL/FR |
1- | undecanol | FL/FR |
woody |
| acetyl cedrene | FR |
| amber carbinol | FR |
| cistus twig/leaf oil | FL/FR |
| guaiacwood oil | FL/FR |
| gurjun balsam oil | FR |
| hydroxyambran | FR |
| methyl cedryl ketone | FL/FR |
| patchouli ethanone | FR |
| patchouli oil | FL/FR |
| santall | FR |
| timber propanol | FR |
| tobacarol (IFF) | FR |
| vetiver oil haiti | FL/FR |
| vetiver specialty | FR |
| woody acetate | FR |
(Z)- | woody amylene | FR |
| woody epoxide | FR |
| woody ether | FR |
| woody propanol | FR |
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For Flavor |
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No flavor group found for these |
| cistus ladaniferus resinoid | FL/FR |
| methyl (E)-cinnamate | FL/FR |
aldehydic |
1- | undecanol | FL/FR |
amber |
| ambrette seed oil | FL/FR |
| ambrette seed oil CO2 extract | FL/FR |
| musk tetralin | FL/FR |
animal |
| indole | FL/FR |
balsamic |
siam | benzoin resinoid | FL/FR |
| benzyl salicylate | FL/FR |
iso | butyl cinnamate | FL/FR |
| ethyl cinnamate | FL/FR |
| myrrh oil | FL/FR |
berry |
| heliotropyl acetone | FL/FR |
| raspberry ketone | FL/FR |
| raspberry ketone acetate | FL/FR |
| raspberry ketone methyl ether | FL/FR |
caramellic |
| ethyl maltol | FL/FR |
cherry |
| heliotropin | FL/FR |
citrus |
laevo- | linalool | FL/FR |
creamy |
gamma- | hexalactone | FL/FR |
para- | methyl acetophenone | FL/FR |
gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
floral |
| bois de rose oil brazil | FL/FR |
| citronellol | FL/FR |
| methyl dihydrojasmonate | FL/FR |
alpha-iso | methyl ionone (50% min.) | FL/FR |
(E)-alpha- | methyl ionone (74-80%) | FL/FR |
alpha-iso | methyl ionone (90% min.) | FL/FR |
| ocean propanal | FL/FR |
| phenethyl alcohol | FL/FR |
| rhodinol | FL/FR |
fruity |
| acetyl methyl anthranilate | FL/FR |
iso | amyl benzoate | FL/FR |
para- | anisyl alcohol | FL/FR |
alpha- | methyl ionone | FL/FR |
| valeriana officinalis root extract | FL/FR |
green |
iso | amyl salicylate | FL/FR |
| angelica root oil | FL/FR |
| cinnamyl alcohol | FL/FR |
| cyclamen aldehyde | FL/FR |
(Z)-3- | hexen-1-yl salicylate | FL/FR |
| linalool oxide | FL/FR |
| nerolidol | FL/FR |
| oakmoss absolute | FL/FR |
| papaya isobutyrate | FL/FR |
herbal |
| clary sage oil france | FL/FR |
| coriander seed oil | FL/FR |
| daucus carota fruit oil | FL/FR |
honey |
| phenethyl phenyl acetate | FL/FR |
lactonic |
gamma- | heptalactone | FL/FR |
gamma- | octalactone | FL/FR |
medicinal |
| dimethyl benzyl carbinol | FL/FR |
phenolic |
para- | cresyl phenyl acetate | FL/FR |
powdery |
beta- | naphthyl ethyl ether | FL/FR |
soapy |
| dodecanal (aldehyde C-12 lauric) | FL/FR |
1- | dodecanol | FL/FR |
spicy |
para- | anisyl formate | FL/FR |
| cassia bark oil china | FL/FR |
iso | eugenyl acetate | FL/FR |
alpha- | methyl cinnamaldehyde | FL/FR |
| methyl isoeugenol | FL/FR |
black | pepper oil | FL/FR |
3- | phenyl propyl alcohol | FL/FR |
tropical |
alpha- | amyl cinnamaldehyde | FL/FR |
vanilla |
| ethyl vanillin | FL/FR |
| vanilla bean absolute (vanilla planifolia) | FL/FR |
| vanillyl acetate | FL/FR |
waxy |
| decanol | FL/FR |
9- | decen-1-ol | FL/FR |
| decyl acetate | FL/FR |
| ethyl laurate | FL/FR |
alpha- | hexyl cinnamaldehyde | FL/FR |
| hydroxycitronellal | FL/FR |
woody |
| ambrette seed absolute | FL/FR |
| ambroxan | FL/FR |
| amyris wood oil | FL/FR |
| cistus twig/leaf oil | FL/FR |
| frankincense oil | FL/FR |
| guaiacwood oil | FL/FR |
| methyl cedryl ketone | FL/FR |
| patchouli oil | FL/FR |
| vetiver oil haiti | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| acetyl hexamethyl indan | 6- | acetyl-1,1,2,3,3,5-hexamethyl indan | 5- | acetyl-1,1,2,3,3,6-hexamethyl indan | 5- | acetyl-1,1,2,3,3,6-hexamethyl-1H-indane | 1-(2,3- | dihydro-1,1,2,3,3,6-hexamethyl-1H-inden-5-yl) ethanone | | fixolide (Givaudan) | | fixolide, kosher | | ganolid (tonalid) | | ganolide | 1-(1,1,2,3,3,6- | hexamethyl-2H-inden-5-yl)ethanone | | INCI acetyl hexamethyl indan | | musk indane | | phantolid (PFW) | | phantolid crystals (PFW) | | tonalid (PFW) |
Articles:
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